1po6

;Crystal Structure of UP1 Complexed With d(TAGG(6MI)TTAGGG): A Human Telomeric Repeat Containing 6-methyl-8-(2-deoxy-beta-ribofuranosyl)isoxanthopteridine (6MI) ;

Method: X-RAY DIFFRACTION Dmax: 67.0 Å Quality: EXCELLENT

SAXS 散射曲线 SAXS Profile

SAXS profile for 1po6

P(r) 距离分布 P(r) Distribution

P(r) distribution for 1po6
下载 Download

1. 结构基本信息 1. Structure Basics

条目编号 entry_id1po6
沉积日期 deposition_date2003-06-13
结构标题 title;Crystal Structure of UP1 Complexed With d(TAGG(6MI)TTAGGG): A Human Telomeric Repeat Containing 6-methyl-8-(2-deoxy-beta-ribofuranosyl)isoxanthopteridine (6MI) ;
关键词 keywords;protein-DNA complex, UP1, human telomeric repeat, hTR, TR2-6F, RRM, RNA Recognition Motif, 6MI, 6-methyl-8-(2-deoxy-beta-ribofuranosyl)isoxanthopteridine, hnRNP A1, RNA Binding Protein-DNA COMPLEX ;; RNA Binding Protein/DNA
实验方法 methodX-RAY DIFFRACTION

2. SAXS 参数 (CRYSOL 理论计算) 2. SAXS Parameters (CRYSOL)

回转半径 Rg (Guinier) rg_guinier21.30
回转半径 Rg (电子) rg_electron20.09
零角强度 I(0) i013453000.00
分子量 molecular_weight24330.0 kDa
排除体积 excluded_volume29140 ų
包络体积 envelope_volume37228 ų
水化壳体积 shell_volume16577 ų
包络直径 envelope_diameter68.0
壳层 Rg shell_rg25.10
包络 Rg envelope_rg20.45
形状 Rg shape_rg20.05
总 Rg total_rg20.88
总原子数 total_atoms1700
残基数 n_residues193
球谐函数阶数 n_harmonics20
q 范围 q_range— – 0.5000 −1
数据点数 n_points101
壳层类型 shell_typedirectional
溶剂电子密度 solvent_density0.3340 e/ų
壳层衬度 contrast_shell0.0300 e/ų
CRYSOL 版本 crysol_version4.1.3

3. P(r) 距离分布 (GNOM 反演) 3. P(r) Analysis (GNOM)

最大尺寸 Dmax dmax67.0
Rg (实空间) rg_real21.32
Rg 误差 (实空间) rg_real_error0.41
I(0) (实空间) i0_real1.3450e+07
I(0) 误差 (实空间) i0_real_error1.7440e+05
Rg (倒空间) rg_reciprocal21.32
I(0) (倒空间) i0_reciprocal13450000.0000
解质量估计 total_estimate0.9080
解质量评级 solution_quality EXCELLENT a EXCELLENT solution
P(r) 峰数 n_peaks2
主峰位置 r_peak_primary21.7
偏度 Skewness skewness0.319
峰度 Kurtosis kurtosis-0.524
角度范围 angular_range— – 0.3750 −1
当前正则化参数 α current_alpha0.0000
最高正则化参数 α highest_alpha1798000.0000
实空间数据点数 n_real_points69
GNOM 版本 gnom_version4.1.3
质量判据 quality_criteria AN1: 0.000; Oscil: 0.945; Stabil: 1.000; Sysdev: 1.000; Positv: 1.000; Valcen: 0.973; Smooth: 0.993

4. 晶体学与实验 4. Crystallography & Experiment

5. 实体与聚合体信息 (3)

6. 折叠分类 (SCOP + CATH) 4 domains

SCOP 2.08 (2 domains)

结构域编号 domain_idd1po6a1
类 Class classd — Alpha and beta proteins (a+b)
折叠类型 Fold foldd.58 — Ferredoxin-like
超家族 Superfamily superfamilyd.58.7 — RNA-binding domain, RBD, aka RNA recognition motif (RRM)
家族 Family familyd.58.7.1 — Canonical RBD
结构域编号 domain_idd1po6a2
类 Class classd — Alpha and beta proteins (a+b)
折叠类型 Fold foldd.58 — Ferredoxin-like
超家族 Superfamily superfamilyd.58.7 — RNA-binding domain, RBD, aka RNA recognition motif (RRM)
家族 Family familyd.58.7.1 — Canonical RBD

CATH v4.4 (2 domains)

结构域编号 domain_id1po6A01
类 Class class3 — Alpha Beta
架构 Architecture architecture30 — 2-Layer Sandwich
拓扑 Topology topology70 — Alpha-Beta Plaits
同源超家族 H-superfamily homologous superfamily330 — RRM (RNA recognition motif) domain
结构域编号 domain_id1po6A02
类 Class class3 — Alpha Beta
架构 Architecture architecture30 — 2-Layer Sandwich
拓扑 Topology topology70 — Alpha-Beta Plaits
同源超家族 H-superfamily homologous superfamily330 — RRM (RNA recognition motif) domain

7. 引用文献 (1)

8. 文件与曲线 (10)