1qdw

N-TERMINAL DOMAIN, VOLTAGE-GATED POTASSIUM CHANNEL KV1.2 RESIDUES 33-119

Method: X-RAY DIFFRACTION D_max: 112.7 Å Quality: GOOD

SAXS 散射曲线 SAXS Profile

P(r) 距离分布 P(r) Distribution

下载 Download SAXS (.dat) P(r) (.pr.out) CIF

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1. 结构基本信息 1. Structure Basics

条目编号 entry_id	1qdw
沉积日期 deposition_date	1999-07-10
结构标题 title	N-TERMINAL DOMAIN, VOLTAGE-GATED POTASSIUM CHANNEL KV1.2 RESIDUES 33-119
关键词 keywords	VOLTAGE-GATED POTASSIUM CHANNEL, TETRAMERIZATION DOMAIN, INTRACELLULAR GATE, TETRAMER, SIGNALING PROTEIN; SIGNALING PROTEIN
实验方法 method	X-RAY DIFFRACTION

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2. SAXS 参数 (CRYSOL 理论计算) 2. SAXS Parameters (CRYSOL)

回转半径 Rg (Guinier) rg_guinier	34.11 Å
回转半径 Rg (电子) rg_electron	34.05 Å
零角强度 I(0) i0	103001000.00
分子量 molecular_weight	83888.0 kDa
排除体积 excluded_volume	106120 Å³
包络体积 envelope_volume	132760 Å³
水化壳体积 shell_volume	34161 Å³
包络直径 envelope_diameter	121.0 Å
壳层 Rg shell_rg	38.45 Å
包络 Rg envelope_rg	33.81 Å
形状 Rg shape_rg	34.02 Å
总 Rg total_rg	34.50 Å
总原子数 total_atoms	5952
残基数 n_residues	696
球谐函数阶数 n_harmonics	20
q 范围 q_range	— – 0.5000 Å⁻¹
数据点数 n_points	101
壳层类型 shell_type	directional
溶剂电子密度 solvent_density	0.3340 e/Å³
壳层衬度 contrast_shell	0.0300 e/Å³
CRYSOL 版本 crysol_version	4.1.3

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3. P(r) 距离分布 (GNOM 反演) 3. P(r) Analysis (GNOM)

最大尺寸 Dmax dmax	112.7 Å
Rg (实空间) rg_real	34.36 Å
Rg 误差 (实空间) rg_real_error	0.89 Å
I(0) (实空间) i0_real	1.0300e+08
I(0) 误差 (实空间) i0_real_error	1.8470e+06
Rg (倒空间) rg_reciprocal	34.21 Å
I(0) (倒空间) i0_reciprocal	103000000.0000
解质量估计 total_estimate	0.8153
解质量评级 solution_quality	GOOD a GOOD solution
P(r) 峰数 n_peaks	1
主峰位置 r_peak_primary	29.4 Å
偏度 Skewness skewness	0.478
峰度 Kurtosis kurtosis	-0.591
角度范围 angular_range	— – 0.2300 Å⁻¹
当前正则化参数 α current_alpha	0.0000
最高正则化参数 α highest_alpha	35630000.0000
实空间数据点数 n_real_points	47
GNOM 版本 gnom_version	4.1.3
质量判据 quality_criteria	AN1: 0.000; Oscil: 0.682; Stabil: 1.000; Sysdev: 1.000; Positv: 1.000; Valcen: 0.828; Smooth: 0.719

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4. 晶体学与实验 4. Crystallography & Experiment

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5. 实体与聚合体信息 (2)

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6. 折叠分类 (SCOP + CATH) 16 domains

SCOP 2.08 (8 domains)

结构域编号 domain_id	d1qdwa_
类 Class class	d — Alpha and beta proteins (a+b)
折叠类型 Fold fold	d.42 — POZ domain
超家族 Superfamily superfamily	d.42.1 — POZ domain
家族 Family family	d.42.1.2 — Tetramerization domain of potassium channels

结构域编号 domain_id	d1qdwb_
类 Class class	d — Alpha and beta proteins (a+b)
折叠类型 Fold fold	d.42 — POZ domain
超家族 Superfamily superfamily	d.42.1 — POZ domain
家族 Family family	d.42.1.2 — Tetramerization domain of potassium channels

结构域编号 domain_id	d1qdwc_
类 Class class	d — Alpha and beta proteins (a+b)
折叠类型 Fold fold	d.42 — POZ domain
超家族 Superfamily superfamily	d.42.1 — POZ domain
家族 Family family	d.42.1.2 — Tetramerization domain of potassium channels

结构域编号 domain_id	d1qdwd_
类 Class class	d — Alpha and beta proteins (a+b)
折叠类型 Fold fold	d.42 — POZ domain
超家族 Superfamily superfamily	d.42.1 — POZ domain
家族 Family family	d.42.1.2 — Tetramerization domain of potassium channels

结构域编号 domain_id	d1qdwe_
类 Class class	d — Alpha and beta proteins (a+b)
折叠类型 Fold fold	d.42 — POZ domain
超家族 Superfamily superfamily	d.42.1 — POZ domain
家族 Family family	d.42.1.2 — Tetramerization domain of potassium channels

结构域编号 domain_id	d1qdwf_
类 Class class	d — Alpha and beta proteins (a+b)
折叠类型 Fold fold	d.42 — POZ domain
超家族 Superfamily superfamily	d.42.1 — POZ domain
家族 Family family	d.42.1.2 — Tetramerization domain of potassium channels

结构域编号 domain_id	d1qdwg_
类 Class class	d — Alpha and beta proteins (a+b)
折叠类型 Fold fold	d.42 — POZ domain
超家族 Superfamily superfamily	d.42.1 — POZ domain
家族 Family family	d.42.1.2 — Tetramerization domain of potassium channels

结构域编号 domain_id	d1qdwh_
类 Class class	d — Alpha and beta proteins (a+b)
折叠类型 Fold fold	d.42 — POZ domain
超家族 Superfamily superfamily	d.42.1 — POZ domain
家族 Family family	d.42.1.2 — Tetramerization domain of potassium channels

CATH v4.4 (8 domains)

结构域编号 domain_id	1qdwA00
类 Class class	3 — Alpha Beta
架构 Architecture architecture	30 — 2-Layer Sandwich
拓扑 Topology topology	710 — Potassium Channel Kv1.1; Chain A
同源超家族 H-superfamily homologous superfamily	10 — Potassium Channel Kv1.1; Chain A

结构域编号 domain_id	1qdwB00
类 Class class	3 — Alpha Beta
架构 Architecture architecture	30 — 2-Layer Sandwich
拓扑 Topology topology	710 — Potassium Channel Kv1.1; Chain A
同源超家族 H-superfamily homologous superfamily	10 — Potassium Channel Kv1.1; Chain A

结构域编号 domain_id	1qdwC00
类 Class class	3 — Alpha Beta
架构 Architecture architecture	30 — 2-Layer Sandwich
拓扑 Topology topology	710 — Potassium Channel Kv1.1; Chain A
同源超家族 H-superfamily homologous superfamily	10 — Potassium Channel Kv1.1; Chain A

结构域编号 domain_id	1qdwD00
类 Class class	3 — Alpha Beta
架构 Architecture architecture	30 — 2-Layer Sandwich
拓扑 Topology topology	710 — Potassium Channel Kv1.1; Chain A
同源超家族 H-superfamily homologous superfamily	10 — Potassium Channel Kv1.1; Chain A

结构域编号 domain_id	1qdwE00
类 Class class	3 — Alpha Beta
架构 Architecture architecture	30 — 2-Layer Sandwich
拓扑 Topology topology	710 — Potassium Channel Kv1.1; Chain A
同源超家族 H-superfamily homologous superfamily	10 — Potassium Channel Kv1.1; Chain A

结构域编号 domain_id	1qdwF00
类 Class class	3 — Alpha Beta
架构 Architecture architecture	30 — 2-Layer Sandwich
拓扑 Topology topology	710 — Potassium Channel Kv1.1; Chain A
同源超家族 H-superfamily homologous superfamily	10 — Potassium Channel Kv1.1; Chain A

结构域编号 domain_id	1qdwG00
类 Class class	3 — Alpha Beta
架构 Architecture architecture	30 — 2-Layer Sandwich
拓扑 Topology topology	710 — Potassium Channel Kv1.1; Chain A
同源超家族 H-superfamily homologous superfamily	10 — Potassium Channel Kv1.1; Chain A

结构域编号 domain_id	1qdwH00
类 Class class	3 — Alpha Beta
架构 Architecture architecture	30 — 2-Layer Sandwich
拓扑 Topology topology	710 — Potassium Channel Kv1.1; Chain A
同源超家族 H-superfamily homologous superfamily	10 — Potassium Channel Kv1.1; Chain A

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7. 引用文献 (1)

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晶胞边长 a length_a	76.260 Å
晶胞边长 b length_b	78.740 Å
晶胞边长 c length_c	125.320 Å
晶胞夹角 α angle_alpha	90.00 °
晶胞夹角 β angle_beta	90.00 °
晶胞夹角 γ angle_gamma	90.00 °
晶胞分子数 Z z_pdb	32

空间群 space_group	P 21 21 21
空间群编号 int_tables_number	19
晶系 crystal_system	—

分辨率 resolution	2.100 Å
最低分辨率 resolution_low	20.000 Å
R 因子 r_factor	0.2230
R_work r_work	0.2230
R_free r_free	0.2660

描述 description	KV1.2 VOLTAGE-GATED POTASSIUM CHANNEL
分子量 formula_weight	10498.0 kDa
来源方法 src_method	man
拷贝数 entity_count	8

聚合体类型 type	polypeptide(L)
链编号 strand_id	A,B,C,D,E,F,G,H
原子数 atom_count	6491

N-TERMINAL DOMAIN, VOLTAGE-GATED POTASSIUM CHANNEL KV1.2 RESIDUES 33-119

SAXS 散射曲线 SAXS Profile

P(r) 距离分布 P(r) Distribution

1. 结构基本信息 1. Structure Basics

2. SAXS 参数 (CRYSOL 理论计算) 2. SAXS Parameters (CRYSOL)

3. P(r) 距离分布 (GNOM 反演) 3. P(r) Analysis (GNOM)

4. 晶体学与实验 4. Crystallography & Experiment

晶胞参数 Unit Cell

对称性 Symmetry

精修参数 Refinement

衍射实验 Diffraction

5. 实体与聚合体信息 (2)

Entity 1 polymer

聚合体 Polymer

来源 Source

Entity 2 water

6. 折叠分类 (SCOP + CATH) 16 domains

SCOP 2.08 (8 domains)

CATH v4.4 (8 domains)

7. 引用文献 (1)

8. 文件与曲线 (10)

Files (7)

Curves (3)

来源生物 organism	Rattus norvegicus
通用名 common_name	Norway rat
NCBI 分类编号 ncbi_taxonomy_id	10116
宿主生物 host_organism	Escherichia coli

描述 description	water
分子量 formula_weight	18.0 kDa
来源方法 src_method	nat
拷贝数 entity_count	539

fit	/app/data/saxs_computation/qd/1qdw/1qdw.fit
pddf	/app/data/pr_computation/qd/1qdw/1qdw.pr.out
profile	/app/data/saxs_computation/qd/1qdw/1qdw.dat