1t5e

The structure of MexA

Method: X-RAY DIFFRACTION Dmax: 231.8 Å Quality: GOOD

SAXS 散射曲线 SAXS Profile

SAXS profile for 1t5e

P(r) 距离分布 P(r) Distribution

P(r) distribution for 1t5e
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1. 结构基本信息 1. Structure Basics

条目编号 entry_id1t5e
沉积日期 deposition_date2004-05-04
结构标题 titleThe structure of MexA
关键词 keywordsMexA, antibiotic efflux pump, periplasmic adaptor protein, TRANSPORT PROTEIN; TRANSPORT PROTEIN
实验方法 methodX-RAY DIFFRACTION

2. SAXS 参数 (CRYSOL 理论计算) 2. SAXS Parameters (CRYSOL)

回转半径 Rg (Guinier) rg_guinier66.67
回转半径 Rg (电子) rg_electron67.60
零角强度 I(0) i01603010000.00
分子量 molecular_weight327890.0 kDa
排除体积 excluded_volume408300 ų
包络体积 envelope_volume663320 ų
水化壳体积 shell_volume91415 ų
包络直径 envelope_diameter228.0
壳层 Rg shell_rg55.98
包络 Rg envelope_rg65.27
形状 Rg shape_rg67.58
总 Rg total_rg67.37
总原子数 total_atoms23101
残基数 n_residues3003
球谐函数阶数 n_harmonics20
q 范围 q_range— – 0.5000 −1
数据点数 n_points101
壳层类型 shell_typedirectional
溶剂电子密度 solvent_density0.3340 e/ų
壳层衬度 contrast_shell0.0300 e/ų
CRYSOL 版本 crysol_version4.1.3

3. P(r) 距离分布 (GNOM 反演) 3. P(r) Analysis (GNOM)

最大尺寸 Dmax dmax231.8
Rg (实空间) rg_real67.19
Rg 误差 (实空间) rg_real_error3.40
I(0) (实空间) i0_real1.6030e+09
I(0) 误差 (实空间) i0_real_error3.4740e+07
Rg (倒空间) rg_reciprocal66.14
I(0) (倒空间) i0_reciprocal1600000000.0000
解质量估计 total_estimate0.8334
解质量评级 solution_quality GOOD a GOOD solution
P(r) 峰数 n_peaks1
主峰位置 r_peak_primary70.5
偏度 Skewness skewness0.409
峰度 Kurtosis kurtosis-0.524
角度范围 angular_range— – 0.1150 −1
当前正则化参数 α current_alpha0.0000
最高正则化参数 α highest_alpha69400000.0000
实空间数据点数 n_real_points24
GNOM 版本 gnom_version4.1.3
质量判据 quality_criteria AN1: 0.000; Oscil: 0.733; Stabil: 1.000; Sysdev: 1.000; Positv: 1.000; Valcen: 0.970; Smooth: 0.662

4. 晶体学与实验 4. Crystallography & Experiment

5. 实体与聚合体信息 (3)

6. 折叠分类 (SCOP + CATH) 52 domains

SCOP 2.08 (13 domains)

结构域编号 domain_idd1t5ea_
类 Class classf — Membrane and cell surface proteins and peptides
折叠类型 Fold foldf.46 — HlyD-like secretion proteins
超家族 Superfamily superfamilyf.46.1 — HlyD-like secretion proteins
家族 Family familyf.46.1.1 — HlyD-like secretion proteins
结构域编号 domain_idd1t5eb_
类 Class classf — Membrane and cell surface proteins and peptides
折叠类型 Fold foldf.46 — HlyD-like secretion proteins
超家族 Superfamily superfamilyf.46.1 — HlyD-like secretion proteins
家族 Family familyf.46.1.1 — HlyD-like secretion proteins
结构域编号 domain_idd1t5ec_
类 Class classf — Membrane and cell surface proteins and peptides
折叠类型 Fold foldf.46 — HlyD-like secretion proteins
超家族 Superfamily superfamilyf.46.1 — HlyD-like secretion proteins
家族 Family familyf.46.1.1 — HlyD-like secretion proteins
结构域编号 domain_idd1t5ed_
类 Class classf — Membrane and cell surface proteins and peptides
折叠类型 Fold foldf.46 — HlyD-like secretion proteins
超家族 Superfamily superfamilyf.46.1 — HlyD-like secretion proteins
家族 Family familyf.46.1.1 — HlyD-like secretion proteins
结构域编号 domain_idd1t5ee_
类 Class classf — Membrane and cell surface proteins and peptides
折叠类型 Fold foldf.46 — HlyD-like secretion proteins
超家族 Superfamily superfamilyf.46.1 — HlyD-like secretion proteins
家族 Family familyf.46.1.1 — HlyD-like secretion proteins
结构域编号 domain_idd1t5ef_
类 Class classf — Membrane and cell surface proteins and peptides
折叠类型 Fold foldf.46 — HlyD-like secretion proteins
超家族 Superfamily superfamilyf.46.1 — HlyD-like secretion proteins
家族 Family familyf.46.1.1 — HlyD-like secretion proteins
结构域编号 domain_idd1t5eg_
类 Class classf — Membrane and cell surface proteins and peptides
折叠类型 Fold foldf.46 — HlyD-like secretion proteins
超家族 Superfamily superfamilyf.46.1 — HlyD-like secretion proteins
家族 Family familyf.46.1.1 — HlyD-like secretion proteins
结构域编号 domain_idd1t5eh_
类 Class classf — Membrane and cell surface proteins and peptides
折叠类型 Fold foldf.46 — HlyD-like secretion proteins
超家族 Superfamily superfamilyf.46.1 — HlyD-like secretion proteins
家族 Family familyf.46.1.1 — HlyD-like secretion proteins
结构域编号 domain_idd1t5ei_
类 Class classf — Membrane and cell surface proteins and peptides
折叠类型 Fold foldf.46 — HlyD-like secretion proteins
超家族 Superfamily superfamilyf.46.1 — HlyD-like secretion proteins
家族 Family familyf.46.1.1 — HlyD-like secretion proteins
结构域编号 domain_idd1t5ej_
类 Class classf — Membrane and cell surface proteins and peptides
折叠类型 Fold foldf.46 — HlyD-like secretion proteins
超家族 Superfamily superfamilyf.46.1 — HlyD-like secretion proteins
家族 Family familyf.46.1.1 — HlyD-like secretion proteins
结构域编号 domain_idd1t5ek_
类 Class classf — Membrane and cell surface proteins and peptides
折叠类型 Fold foldf.46 — HlyD-like secretion proteins
超家族 Superfamily superfamilyf.46.1 — HlyD-like secretion proteins
家族 Family familyf.46.1.1 — HlyD-like secretion proteins
结构域编号 domain_idd1t5el_
类 Class classf — Membrane and cell surface proteins and peptides
折叠类型 Fold foldf.46 — HlyD-like secretion proteins
超家族 Superfamily superfamilyf.46.1 — HlyD-like secretion proteins
家族 Family familyf.46.1.1 — HlyD-like secretion proteins
结构域编号 domain_idd1t5em_
类 Class classf — Membrane and cell surface proteins and peptides
折叠类型 Fold foldf.46 — HlyD-like secretion proteins
超家族 Superfamily superfamilyf.46.1 — HlyD-like secretion proteins
家族 Family familyf.46.1.1 — HlyD-like secretion proteins

CATH v4.4 (39 domains)

结构域编号 domain_id1t5eA01
类 Class class2 — Mainly Beta
架构 Architecture architecture40 — Beta Barrel
拓扑 Topology topology30 — Elongation Factor Tu (Ef-tu); domain 3
同源超家族 H-superfamily homologous superfamily170 — Efflux pump adaptor protein, beta barrel domain
结构域编号 domain_id1t5eA02
类 Class class2 — Mainly Beta
架构 Architecture architecture40 — Beta Barrel
拓扑 Topology topology50 — OB fold (Dihydrolipoamide Acetyltransferase, E2P)
同源超家族 H-superfamily homologous superfamily100 — RNA polymerase II/Efflux pump adaptor protein, barrel-sandwich hybrid domain
结构域编号 domain_id1t5eA03
类 Class class1 — Mainly Alpha
架构 Architecture architecture10 — Orthogonal Bundle
拓扑 Topology topology287 — Helix Hairpins
同源超家族 H-superfamily homologous superfamily470 — Helix hairpin bin
结构域编号 domain_id1t5eB01
类 Class class2 — Mainly Beta
架构 Architecture architecture40 — Beta Barrel
拓扑 Topology topology30 — Elongation Factor Tu (Ef-tu); domain 3
同源超家族 H-superfamily homologous superfamily170 — Efflux pump adaptor protein, beta barrel domain
结构域编号 domain_id1t5eB02
类 Class class2 — Mainly Beta
架构 Architecture architecture40 — Beta Barrel
拓扑 Topology topology50 — OB fold (Dihydrolipoamide Acetyltransferase, E2P)
同源超家族 H-superfamily homologous superfamily100 — RNA polymerase II/Efflux pump adaptor protein, barrel-sandwich hybrid domain
结构域编号 domain_id1t5eB03
类 Class class1 — Mainly Alpha
架构 Architecture architecture10 — Orthogonal Bundle
拓扑 Topology topology287 — Helix Hairpins
同源超家族 H-superfamily homologous superfamily470 — Helix hairpin bin
结构域编号 domain_id1t5eC01
类 Class class2 — Mainly Beta
架构 Architecture architecture40 — Beta Barrel
拓扑 Topology topology30 — Elongation Factor Tu (Ef-tu); domain 3
同源超家族 H-superfamily homologous superfamily170 — Efflux pump adaptor protein, beta barrel domain
结构域编号 domain_id1t5eC02
类 Class class2 — Mainly Beta
架构 Architecture architecture40 — Beta Barrel
拓扑 Topology topology50 — OB fold (Dihydrolipoamide Acetyltransferase, E2P)
同源超家族 H-superfamily homologous superfamily100 — RNA polymerase II/Efflux pump adaptor protein, barrel-sandwich hybrid domain
结构域编号 domain_id1t5eC03
类 Class class1 — Mainly Alpha
架构 Architecture architecture10 — Orthogonal Bundle
拓扑 Topology topology287 — Helix Hairpins
同源超家族 H-superfamily homologous superfamily470 — Helix hairpin bin
结构域编号 domain_id1t5eD01
类 Class class2 — Mainly Beta
架构 Architecture architecture40 — Beta Barrel
拓扑 Topology topology30 — Elongation Factor Tu (Ef-tu); domain 3
同源超家族 H-superfamily homologous superfamily170 — Efflux pump adaptor protein, beta barrel domain
结构域编号 domain_id1t5eD02
类 Class class2 — Mainly Beta
架构 Architecture architecture40 — Beta Barrel
拓扑 Topology topology50 — OB fold (Dihydrolipoamide Acetyltransferase, E2P)
同源超家族 H-superfamily homologous superfamily100 — RNA polymerase II/Efflux pump adaptor protein, barrel-sandwich hybrid domain
结构域编号 domain_id1t5eD03
类 Class class1 — Mainly Alpha
架构 Architecture architecture10 — Orthogonal Bundle
拓扑 Topology topology287 — Helix Hairpins
同源超家族 H-superfamily homologous superfamily470 — Helix hairpin bin
结构域编号 domain_id1t5eE01
类 Class class2 — Mainly Beta
架构 Architecture architecture40 — Beta Barrel
拓扑 Topology topology30 — Elongation Factor Tu (Ef-tu); domain 3
同源超家族 H-superfamily homologous superfamily170 — Efflux pump adaptor protein, beta barrel domain
结构域编号 domain_id1t5eE02
类 Class class2 — Mainly Beta
架构 Architecture architecture40 — Beta Barrel
拓扑 Topology topology50 — OB fold (Dihydrolipoamide Acetyltransferase, E2P)
同源超家族 H-superfamily homologous superfamily100 — RNA polymerase II/Efflux pump adaptor protein, barrel-sandwich hybrid domain
结构域编号 domain_id1t5eE03
类 Class class1 — Mainly Alpha
架构 Architecture architecture10 — Orthogonal Bundle
拓扑 Topology topology287 — Helix Hairpins
同源超家族 H-superfamily homologous superfamily470 — Helix hairpin bin
结构域编号 domain_id1t5eF01
类 Class class2 — Mainly Beta
架构 Architecture architecture40 — Beta Barrel
拓扑 Topology topology30 — Elongation Factor Tu (Ef-tu); domain 3
同源超家族 H-superfamily homologous superfamily170 — Efflux pump adaptor protein, beta barrel domain
结构域编号 domain_id1t5eF02
类 Class class2 — Mainly Beta
架构 Architecture architecture40 — Beta Barrel
拓扑 Topology topology50 — OB fold (Dihydrolipoamide Acetyltransferase, E2P)
同源超家族 H-superfamily homologous superfamily100 — RNA polymerase II/Efflux pump adaptor protein, barrel-sandwich hybrid domain
结构域编号 domain_id1t5eF03
类 Class class1 — Mainly Alpha
架构 Architecture architecture10 — Orthogonal Bundle
拓扑 Topology topology287 — Helix Hairpins
同源超家族 H-superfamily homologous superfamily470 — Helix hairpin bin
结构域编号 domain_id1t5eG01
类 Class class2 — Mainly Beta
架构 Architecture architecture40 — Beta Barrel
拓扑 Topology topology30 — Elongation Factor Tu (Ef-tu); domain 3
同源超家族 H-superfamily homologous superfamily170 — Efflux pump adaptor protein, beta barrel domain
结构域编号 domain_id1t5eG02
类 Class class2 — Mainly Beta
架构 Architecture architecture40 — Beta Barrel
拓扑 Topology topology50 — OB fold (Dihydrolipoamide Acetyltransferase, E2P)
同源超家族 H-superfamily homologous superfamily100 — RNA polymerase II/Efflux pump adaptor protein, barrel-sandwich hybrid domain
结构域编号 domain_id1t5eG03
类 Class class1 — Mainly Alpha
架构 Architecture architecture10 — Orthogonal Bundle
拓扑 Topology topology287 — Helix Hairpins
同源超家族 H-superfamily homologous superfamily470 — Helix hairpin bin
结构域编号 domain_id1t5eH01
类 Class class2 — Mainly Beta
架构 Architecture architecture40 — Beta Barrel
拓扑 Topology topology30 — Elongation Factor Tu (Ef-tu); domain 3
同源超家族 H-superfamily homologous superfamily170 — Efflux pump adaptor protein, beta barrel domain
结构域编号 domain_id1t5eH02
类 Class class2 — Mainly Beta
架构 Architecture architecture40 — Beta Barrel
拓扑 Topology topology50 — OB fold (Dihydrolipoamide Acetyltransferase, E2P)
同源超家族 H-superfamily homologous superfamily100 — RNA polymerase II/Efflux pump adaptor protein, barrel-sandwich hybrid domain
结构域编号 domain_id1t5eH03
类 Class class1 — Mainly Alpha
架构 Architecture architecture10 — Orthogonal Bundle
拓扑 Topology topology287 — Helix Hairpins
同源超家族 H-superfamily homologous superfamily470 — Helix hairpin bin
结构域编号 domain_id1t5eI01
类 Class class2 — Mainly Beta
架构 Architecture architecture40 — Beta Barrel
拓扑 Topology topology30 — Elongation Factor Tu (Ef-tu); domain 3
同源超家族 H-superfamily homologous superfamily170 — Efflux pump adaptor protein, beta barrel domain
结构域编号 domain_id1t5eI02
类 Class class2 — Mainly Beta
架构 Architecture architecture40 — Beta Barrel
拓扑 Topology topology50 — OB fold (Dihydrolipoamide Acetyltransferase, E2P)
同源超家族 H-superfamily homologous superfamily100 — RNA polymerase II/Efflux pump adaptor protein, barrel-sandwich hybrid domain
结构域编号 domain_id1t5eI03
类 Class class1 — Mainly Alpha
架构 Architecture architecture10 — Orthogonal Bundle
拓扑 Topology topology287 — Helix Hairpins
同源超家族 H-superfamily homologous superfamily470 — Helix hairpin bin
结构域编号 domain_id1t5eJ01
类 Class class2 — Mainly Beta
架构 Architecture architecture40 — Beta Barrel
拓扑 Topology topology30 — Elongation Factor Tu (Ef-tu); domain 3
同源超家族 H-superfamily homologous superfamily170 — Efflux pump adaptor protein, beta barrel domain
结构域编号 domain_id1t5eJ02
类 Class class2 — Mainly Beta
架构 Architecture architecture40 — Beta Barrel
拓扑 Topology topology50 — OB fold (Dihydrolipoamide Acetyltransferase, E2P)
同源超家族 H-superfamily homologous superfamily100 — RNA polymerase II/Efflux pump adaptor protein, barrel-sandwich hybrid domain
结构域编号 domain_id1t5eJ03
类 Class class1 — Mainly Alpha
架构 Architecture architecture10 — Orthogonal Bundle
拓扑 Topology topology287 — Helix Hairpins
同源超家族 H-superfamily homologous superfamily470 — Helix hairpin bin
结构域编号 domain_id1t5eK01
类 Class class2 — Mainly Beta
架构 Architecture architecture40 — Beta Barrel
拓扑 Topology topology30 — Elongation Factor Tu (Ef-tu); domain 3
同源超家族 H-superfamily homologous superfamily170 — Efflux pump adaptor protein, beta barrel domain
结构域编号 domain_id1t5eK02
类 Class class2 — Mainly Beta
架构 Architecture architecture40 — Beta Barrel
拓扑 Topology topology50 — OB fold (Dihydrolipoamide Acetyltransferase, E2P)
同源超家族 H-superfamily homologous superfamily100 — RNA polymerase II/Efflux pump adaptor protein, barrel-sandwich hybrid domain
结构域编号 domain_id1t5eK03
类 Class class1 — Mainly Alpha
架构 Architecture architecture10 — Orthogonal Bundle
拓扑 Topology topology287 — Helix Hairpins
同源超家族 H-superfamily homologous superfamily470 — Helix hairpin bin
结构域编号 domain_id1t5eL01
类 Class class2 — Mainly Beta
架构 Architecture architecture40 — Beta Barrel
拓扑 Topology topology30 — Elongation Factor Tu (Ef-tu); domain 3
同源超家族 H-superfamily homologous superfamily170 — Efflux pump adaptor protein, beta barrel domain
结构域编号 domain_id1t5eL02
类 Class class2 — Mainly Beta
架构 Architecture architecture40 — Beta Barrel
拓扑 Topology topology50 — OB fold (Dihydrolipoamide Acetyltransferase, E2P)
同源超家族 H-superfamily homologous superfamily100 — RNA polymerase II/Efflux pump adaptor protein, barrel-sandwich hybrid domain
结构域编号 domain_id1t5eL03
类 Class class1 — Mainly Alpha
架构 Architecture architecture10 — Orthogonal Bundle
拓扑 Topology topology287 — Helix Hairpins
同源超家族 H-superfamily homologous superfamily470 — Helix hairpin bin
结构域编号 domain_id1t5eM01
类 Class class2 — Mainly Beta
架构 Architecture architecture40 — Beta Barrel
拓扑 Topology topology30 — Elongation Factor Tu (Ef-tu); domain 3
同源超家族 H-superfamily homologous superfamily170 — Efflux pump adaptor protein, beta barrel domain
结构域编号 domain_id1t5eM02
类 Class class2 — Mainly Beta
架构 Architecture architecture40 — Beta Barrel
拓扑 Topology topology50 — OB fold (Dihydrolipoamide Acetyltransferase, E2P)
同源超家族 H-superfamily homologous superfamily100 — RNA polymerase II/Efflux pump adaptor protein, barrel-sandwich hybrid domain
结构域编号 domain_id1t5eM03
类 Class class1 — Mainly Alpha
架构 Architecture architecture10 — Orthogonal Bundle
拓扑 Topology topology287 — Helix Hairpins
同源超家族 H-superfamily homologous superfamily470 — Helix hairpin bin

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