1vf7

Crystal structure of the membrane fusion protein, MexA of the multidrug transporter

Method: X-RAY DIFFRACTION Dmax: 236.6 Å Quality: GOOD

SAXS 散射曲线 SAXS Profile

SAXS profile for 1vf7

P(r) 距离分布 P(r) Distribution

P(r) distribution for 1vf7
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1. 结构基本信息 1. Structure Basics

条目编号 entry_id1vf7
沉积日期 deposition_date2004-04-09
结构标题 titleCrystal structure of the membrane fusion protein, MexA of the multidrug transporter
关键词 keywordsalpha hairpin, beta barrel, MEMBRANE PROTEIN; MEMBRANE PROTEIN
实验方法 methodX-RAY DIFFRACTION

2. SAXS 参数 (CRYSOL 理论计算) 2. SAXS Parameters (CRYSOL)

回转半径 Rg (Guinier) rg_guinier68.05
回转半径 Rg (电子) rg_electron68.68
零角强度 I(0) i01679630000.00
分子量 molecular_weight335710.0 kDa
排除体积 excluded_volume417960 ų
包络体积 envelope_volume683790 ų
水化壳体积 shell_volume92414 ų
包络直径 envelope_diameter236.9
壳层 Rg shell_rg56.49
包络 Rg envelope_rg66.96
形状 Rg shape_rg68.66
总 Rg total_rg68.47
总原子数 total_atoms23655
残基数 n_residues3085
球谐函数阶数 n_harmonics20
q 范围 q_range— – 0.5000 −1
数据点数 n_points101
壳层类型 shell_typedirectional
溶剂电子密度 solvent_density0.3340 e/ų
壳层衬度 contrast_shell0.0300 e/ų
CRYSOL 版本 crysol_version4.1.3

3. P(r) 距离分布 (GNOM 反演) 3. P(r) Analysis (GNOM)

最大尺寸 Dmax dmax236.6
Rg (实空间) rg_real68.29
Rg 误差 (实空间) rg_real_error2.77
I(0) (实空间) i0_real1.6800e+09
I(0) 误差 (实空间) i0_real_error3.9090e+07
Rg (倒空间) rg_reciprocal67.08
I(0) (倒空间) i0_reciprocal1676000000.0000
解质量估计 total_estimate0.8261
解质量评级 solution_quality GOOD a GOOD solution
P(r) 峰数 n_peaks1
主峰位置 r_peak_primary72.0
偏度 Skewness skewness0.424
峰度 Kurtosis kurtosis-0.518
角度范围 angular_range— – 0.1150 −1
当前正则化参数 α current_alpha0.0002
最高正则化参数 α highest_alpha75080000.0000
实空间数据点数 n_real_points24
GNOM 版本 gnom_version4.1.3
质量判据 quality_criteria AN1: 0.000; Oscil: 0.723; Stabil: 1.000; Sysdev: 1.000; Positv: 1.000; Valcen: 0.957; Smooth: 0.609

4. 晶体学与实验 4. Crystallography & Experiment

5. 实体与聚合体信息 (1)

6. 折叠分类 (SCOP + CATH) 52 domains

SCOP 2.08 (13 domains)

结构域编号 domain_idd1vf7a_
类 Class classf — Membrane and cell surface proteins and peptides
折叠类型 Fold foldf.46 — HlyD-like secretion proteins
超家族 Superfamily superfamilyf.46.1 — HlyD-like secretion proteins
家族 Family familyf.46.1.1 — HlyD-like secretion proteins
结构域编号 domain_idd1vf7b_
类 Class classf — Membrane and cell surface proteins and peptides
折叠类型 Fold foldf.46 — HlyD-like secretion proteins
超家族 Superfamily superfamilyf.46.1 — HlyD-like secretion proteins
家族 Family familyf.46.1.1 — HlyD-like secretion proteins
结构域编号 domain_idd1vf7c_
类 Class classf — Membrane and cell surface proteins and peptides
折叠类型 Fold foldf.46 — HlyD-like secretion proteins
超家族 Superfamily superfamilyf.46.1 — HlyD-like secretion proteins
家族 Family familyf.46.1.1 — HlyD-like secretion proteins
结构域编号 domain_idd1vf7d_
类 Class classf — Membrane and cell surface proteins and peptides
折叠类型 Fold foldf.46 — HlyD-like secretion proteins
超家族 Superfamily superfamilyf.46.1 — HlyD-like secretion proteins
家族 Family familyf.46.1.1 — HlyD-like secretion proteins
结构域编号 domain_idd1vf7e_
类 Class classf — Membrane and cell surface proteins and peptides
折叠类型 Fold foldf.46 — HlyD-like secretion proteins
超家族 Superfamily superfamilyf.46.1 — HlyD-like secretion proteins
家族 Family familyf.46.1.1 — HlyD-like secretion proteins
结构域编号 domain_idd1vf7f_
类 Class classf — Membrane and cell surface proteins and peptides
折叠类型 Fold foldf.46 — HlyD-like secretion proteins
超家族 Superfamily superfamilyf.46.1 — HlyD-like secretion proteins
家族 Family familyf.46.1.1 — HlyD-like secretion proteins
结构域编号 domain_idd1vf7g_
类 Class classf — Membrane and cell surface proteins and peptides
折叠类型 Fold foldf.46 — HlyD-like secretion proteins
超家族 Superfamily superfamilyf.46.1 — HlyD-like secretion proteins
家族 Family familyf.46.1.1 — HlyD-like secretion proteins
结构域编号 domain_idd1vf7h_
类 Class classf — Membrane and cell surface proteins and peptides
折叠类型 Fold foldf.46 — HlyD-like secretion proteins
超家族 Superfamily superfamilyf.46.1 — HlyD-like secretion proteins
家族 Family familyf.46.1.1 — HlyD-like secretion proteins
结构域编号 domain_idd1vf7i_
类 Class classf — Membrane and cell surface proteins and peptides
折叠类型 Fold foldf.46 — HlyD-like secretion proteins
超家族 Superfamily superfamilyf.46.1 — HlyD-like secretion proteins
家族 Family familyf.46.1.1 — HlyD-like secretion proteins
结构域编号 domain_idd1vf7j_
类 Class classf — Membrane and cell surface proteins and peptides
折叠类型 Fold foldf.46 — HlyD-like secretion proteins
超家族 Superfamily superfamilyf.46.1 — HlyD-like secretion proteins
家族 Family familyf.46.1.1 — HlyD-like secretion proteins
结构域编号 domain_idd1vf7k_
类 Class classf — Membrane and cell surface proteins and peptides
折叠类型 Fold foldf.46 — HlyD-like secretion proteins
超家族 Superfamily superfamilyf.46.1 — HlyD-like secretion proteins
家族 Family familyf.46.1.1 — HlyD-like secretion proteins
结构域编号 domain_idd1vf7l_
类 Class classf — Membrane and cell surface proteins and peptides
折叠类型 Fold foldf.46 — HlyD-like secretion proteins
超家族 Superfamily superfamilyf.46.1 — HlyD-like secretion proteins
家族 Family familyf.46.1.1 — HlyD-like secretion proteins
结构域编号 domain_idd1vf7m_
类 Class classf — Membrane and cell surface proteins and peptides
折叠类型 Fold foldf.46 — HlyD-like secretion proteins
超家族 Superfamily superfamilyf.46.1 — HlyD-like secretion proteins
家族 Family familyf.46.1.1 — HlyD-like secretion proteins

CATH v4.4 (39 domains)

结构域编号 domain_id1vf7A01
类 Class class2 — Mainly Beta
架构 Architecture architecture40 — Beta Barrel
拓扑 Topology topology30 — Elongation Factor Tu (Ef-tu); domain 3
同源超家族 H-superfamily homologous superfamily170 — Efflux pump adaptor protein, beta barrel domain
结构域编号 domain_id1vf7A02
类 Class class2 — Mainly Beta
架构 Architecture architecture40 — Beta Barrel
拓扑 Topology topology50 — OB fold (Dihydrolipoamide Acetyltransferase, E2P)
同源超家族 H-superfamily homologous superfamily100 — RNA polymerase II/Efflux pump adaptor protein, barrel-sandwich hybrid domain
结构域编号 domain_id1vf7A03
类 Class class1 — Mainly Alpha
架构 Architecture architecture10 — Orthogonal Bundle
拓扑 Topology topology287 — Helix Hairpins
同源超家族 H-superfamily homologous superfamily470 — Helix hairpin bin
结构域编号 domain_id1vf7B01
类 Class class2 — Mainly Beta
架构 Architecture architecture40 — Beta Barrel
拓扑 Topology topology30 — Elongation Factor Tu (Ef-tu); domain 3
同源超家族 H-superfamily homologous superfamily170 — Efflux pump adaptor protein, beta barrel domain
结构域编号 domain_id1vf7B02
类 Class class2 — Mainly Beta
架构 Architecture architecture40 — Beta Barrel
拓扑 Topology topology50 — OB fold (Dihydrolipoamide Acetyltransferase, E2P)
同源超家族 H-superfamily homologous superfamily100 — RNA polymerase II/Efflux pump adaptor protein, barrel-sandwich hybrid domain
结构域编号 domain_id1vf7B03
类 Class class1 — Mainly Alpha
架构 Architecture architecture10 — Orthogonal Bundle
拓扑 Topology topology287 — Helix Hairpins
同源超家族 H-superfamily homologous superfamily470 — Helix hairpin bin
结构域编号 domain_id1vf7C01
类 Class class2 — Mainly Beta
架构 Architecture architecture40 — Beta Barrel
拓扑 Topology topology30 — Elongation Factor Tu (Ef-tu); domain 3
同源超家族 H-superfamily homologous superfamily170 — Efflux pump adaptor protein, beta barrel domain
结构域编号 domain_id1vf7C02
类 Class class2 — Mainly Beta
架构 Architecture architecture40 — Beta Barrel
拓扑 Topology topology50 — OB fold (Dihydrolipoamide Acetyltransferase, E2P)
同源超家族 H-superfamily homologous superfamily100 — RNA polymerase II/Efflux pump adaptor protein, barrel-sandwich hybrid domain
结构域编号 domain_id1vf7C03
类 Class class1 — Mainly Alpha
架构 Architecture architecture10 — Orthogonal Bundle
拓扑 Topology topology287 — Helix Hairpins
同源超家族 H-superfamily homologous superfamily470 — Helix hairpin bin
结构域编号 domain_id1vf7D01
类 Class class2 — Mainly Beta
架构 Architecture architecture40 — Beta Barrel
拓扑 Topology topology30 — Elongation Factor Tu (Ef-tu); domain 3
同源超家族 H-superfamily homologous superfamily170 — Efflux pump adaptor protein, beta barrel domain
结构域编号 domain_id1vf7D02
类 Class class2 — Mainly Beta
架构 Architecture architecture40 — Beta Barrel
拓扑 Topology topology50 — OB fold (Dihydrolipoamide Acetyltransferase, E2P)
同源超家族 H-superfamily homologous superfamily100 — RNA polymerase II/Efflux pump adaptor protein, barrel-sandwich hybrid domain
结构域编号 domain_id1vf7D03
类 Class class1 — Mainly Alpha
架构 Architecture architecture10 — Orthogonal Bundle
拓扑 Topology topology287 — Helix Hairpins
同源超家族 H-superfamily homologous superfamily470 — Helix hairpin bin
结构域编号 domain_id1vf7E01
类 Class class2 — Mainly Beta
架构 Architecture architecture40 — Beta Barrel
拓扑 Topology topology30 — Elongation Factor Tu (Ef-tu); domain 3
同源超家族 H-superfamily homologous superfamily170 — Efflux pump adaptor protein, beta barrel domain
结构域编号 domain_id1vf7E02
类 Class class2 — Mainly Beta
架构 Architecture architecture40 — Beta Barrel
拓扑 Topology topology50 — OB fold (Dihydrolipoamide Acetyltransferase, E2P)
同源超家族 H-superfamily homologous superfamily100 — RNA polymerase II/Efflux pump adaptor protein, barrel-sandwich hybrid domain
结构域编号 domain_id1vf7E03
类 Class class1 — Mainly Alpha
架构 Architecture architecture10 — Orthogonal Bundle
拓扑 Topology topology287 — Helix Hairpins
同源超家族 H-superfamily homologous superfamily470 — Helix hairpin bin
结构域编号 domain_id1vf7F01
类 Class class2 — Mainly Beta
架构 Architecture architecture40 — Beta Barrel
拓扑 Topology topology30 — Elongation Factor Tu (Ef-tu); domain 3
同源超家族 H-superfamily homologous superfamily170 — Efflux pump adaptor protein, beta barrel domain
结构域编号 domain_id1vf7F02
类 Class class2 — Mainly Beta
架构 Architecture architecture40 — Beta Barrel
拓扑 Topology topology50 — OB fold (Dihydrolipoamide Acetyltransferase, E2P)
同源超家族 H-superfamily homologous superfamily100 — RNA polymerase II/Efflux pump adaptor protein, barrel-sandwich hybrid domain
结构域编号 domain_id1vf7F03
类 Class class1 — Mainly Alpha
架构 Architecture architecture10 — Orthogonal Bundle
拓扑 Topology topology287 — Helix Hairpins
同源超家族 H-superfamily homologous superfamily470 — Helix hairpin bin
结构域编号 domain_id1vf7G01
类 Class class2 — Mainly Beta
架构 Architecture architecture40 — Beta Barrel
拓扑 Topology topology30 — Elongation Factor Tu (Ef-tu); domain 3
同源超家族 H-superfamily homologous superfamily170 — Efflux pump adaptor protein, beta barrel domain
结构域编号 domain_id1vf7G02
类 Class class2 — Mainly Beta
架构 Architecture architecture40 — Beta Barrel
拓扑 Topology topology50 — OB fold (Dihydrolipoamide Acetyltransferase, E2P)
同源超家族 H-superfamily homologous superfamily100 — RNA polymerase II/Efflux pump adaptor protein, barrel-sandwich hybrid domain
结构域编号 domain_id1vf7G03
类 Class class1 — Mainly Alpha
架构 Architecture architecture10 — Orthogonal Bundle
拓扑 Topology topology287 — Helix Hairpins
同源超家族 H-superfamily homologous superfamily470 — Helix hairpin bin
结构域编号 domain_id1vf7H01
类 Class class2 — Mainly Beta
架构 Architecture architecture40 — Beta Barrel
拓扑 Topology topology30 — Elongation Factor Tu (Ef-tu); domain 3
同源超家族 H-superfamily homologous superfamily170 — Efflux pump adaptor protein, beta barrel domain
结构域编号 domain_id1vf7H02
类 Class class2 — Mainly Beta
架构 Architecture architecture40 — Beta Barrel
拓扑 Topology topology50 — OB fold (Dihydrolipoamide Acetyltransferase, E2P)
同源超家族 H-superfamily homologous superfamily100 — RNA polymerase II/Efflux pump adaptor protein, barrel-sandwich hybrid domain
结构域编号 domain_id1vf7H03
类 Class class1 — Mainly Alpha
架构 Architecture architecture10 — Orthogonal Bundle
拓扑 Topology topology287 — Helix Hairpins
同源超家族 H-superfamily homologous superfamily470 — Helix hairpin bin
结构域编号 domain_id1vf7I01
类 Class class2 — Mainly Beta
架构 Architecture architecture40 — Beta Barrel
拓扑 Topology topology30 — Elongation Factor Tu (Ef-tu); domain 3
同源超家族 H-superfamily homologous superfamily170 — Efflux pump adaptor protein, beta barrel domain
结构域编号 domain_id1vf7I02
类 Class class2 — Mainly Beta
架构 Architecture architecture40 — Beta Barrel
拓扑 Topology topology50 — OB fold (Dihydrolipoamide Acetyltransferase, E2P)
同源超家族 H-superfamily homologous superfamily100 — RNA polymerase II/Efflux pump adaptor protein, barrel-sandwich hybrid domain
结构域编号 domain_id1vf7I03
类 Class class1 — Mainly Alpha
架构 Architecture architecture10 — Orthogonal Bundle
拓扑 Topology topology287 — Helix Hairpins
同源超家族 H-superfamily homologous superfamily470 — Helix hairpin bin
结构域编号 domain_id1vf7J01
类 Class class2 — Mainly Beta
架构 Architecture architecture40 — Beta Barrel
拓扑 Topology topology30 — Elongation Factor Tu (Ef-tu); domain 3
同源超家族 H-superfamily homologous superfamily170 — Efflux pump adaptor protein, beta barrel domain
结构域编号 domain_id1vf7J02
类 Class class2 — Mainly Beta
架构 Architecture architecture40 — Beta Barrel
拓扑 Topology topology50 — OB fold (Dihydrolipoamide Acetyltransferase, E2P)
同源超家族 H-superfamily homologous superfamily100 — RNA polymerase II/Efflux pump adaptor protein, barrel-sandwich hybrid domain
结构域编号 domain_id1vf7J03
类 Class class1 — Mainly Alpha
架构 Architecture architecture10 — Orthogonal Bundle
拓扑 Topology topology287 — Helix Hairpins
同源超家族 H-superfamily homologous superfamily470 — Helix hairpin bin
结构域编号 domain_id1vf7K01
类 Class class2 — Mainly Beta
架构 Architecture architecture40 — Beta Barrel
拓扑 Topology topology30 — Elongation Factor Tu (Ef-tu); domain 3
同源超家族 H-superfamily homologous superfamily170 — Efflux pump adaptor protein, beta barrel domain
结构域编号 domain_id1vf7K02
类 Class class2 — Mainly Beta
架构 Architecture architecture40 — Beta Barrel
拓扑 Topology topology50 — OB fold (Dihydrolipoamide Acetyltransferase, E2P)
同源超家族 H-superfamily homologous superfamily100 — RNA polymerase II/Efflux pump adaptor protein, barrel-sandwich hybrid domain
结构域编号 domain_id1vf7K03
类 Class class1 — Mainly Alpha
架构 Architecture architecture10 — Orthogonal Bundle
拓扑 Topology topology287 — Helix Hairpins
同源超家族 H-superfamily homologous superfamily470 — Helix hairpin bin
结构域编号 domain_id1vf7L01
类 Class class2 — Mainly Beta
架构 Architecture architecture40 — Beta Barrel
拓扑 Topology topology30 — Elongation Factor Tu (Ef-tu); domain 3
同源超家族 H-superfamily homologous superfamily170 — Efflux pump adaptor protein, beta barrel domain
结构域编号 domain_id1vf7L02
类 Class class2 — Mainly Beta
架构 Architecture architecture40 — Beta Barrel
拓扑 Topology topology50 — OB fold (Dihydrolipoamide Acetyltransferase, E2P)
同源超家族 H-superfamily homologous superfamily100 — RNA polymerase II/Efflux pump adaptor protein, barrel-sandwich hybrid domain
结构域编号 domain_id1vf7L03
类 Class class1 — Mainly Alpha
架构 Architecture architecture10 — Orthogonal Bundle
拓扑 Topology topology287 — Helix Hairpins
同源超家族 H-superfamily homologous superfamily470 — Helix hairpin bin
结构域编号 domain_id1vf7M01
类 Class class2 — Mainly Beta
架构 Architecture architecture40 — Beta Barrel
拓扑 Topology topology30 — Elongation Factor Tu (Ef-tu); domain 3
同源超家族 H-superfamily homologous superfamily170 — Efflux pump adaptor protein, beta barrel domain
结构域编号 domain_id1vf7M02
类 Class class2 — Mainly Beta
架构 Architecture architecture40 — Beta Barrel
拓扑 Topology topology50 — OB fold (Dihydrolipoamide Acetyltransferase, E2P)
同源超家族 H-superfamily homologous superfamily100 — RNA polymerase II/Efflux pump adaptor protein, barrel-sandwich hybrid domain
结构域编号 domain_id1vf7M03
类 Class class1 — Mainly Alpha
架构 Architecture architecture10 — Orthogonal Bundle
拓扑 Topology topology287 — Helix Hairpins
同源超家族 H-superfamily homologous superfamily470 — Helix hairpin bin

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