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2aem

Crystal Structures of the MthK RCK Domain

Method: X-RAY DIFFRACTION
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1. Protein Identity and Related Structures Protein Identity & Related Structures

Calcium-gated potassium channel mthK

Methanothermobacter thermautotrophicus

UniProt O27564

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein homooligomer Homooligomer Protein 2 water × 2 Consistent with protein count

Other States of the Same Protein in the Database

Monomer
4ei2 4ei2 4ei2 4ei2 4ei2 4ei2 4ei2 4ei2 4ei2 4ei2 4ei2 4ei2

16 assemblies; showing the first 12

Homodimer
2aef 2aej 2aem 2ogu 3kxd 3rbx 3rbx 3rbx 4l73 4l74 4l75 4l75

16 assemblies; showing the first 12

Homotetramer
3ldc 3ldd 3lde 3ous 3r65 4hyo 4hyo 4hz3 4hz3 4qe7 4qe9 6u9p

15 assemblies; showing the first 12

Other homooligomers
1lnq 2fy8 2fy8 2ogu 3rbz 4ro0 4ro0 4ro0 4ro0 4ro0 5bki 5bkj

30 assemblies; showing the first 12

Heteromeric or nucleic-acid complex

None

View Construct and Data Evidence
UniProt name MTHK_METTH
Isoform —
PDB entities 1
Chains and sequence ranges Author chain A； PDBConstruct 1–230； UniProt 107–336

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

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2. Structure Basics 2. Structure Basics

Entry ID entry_id2aem
Deposition date deposition_date2005-07-22
Structure title titleCrystal Structures of the MthK RCK Domain
Keywords keywordsRossmann fold, helix-turn-helix, METAL TRANSPORT, MEMBRANE PROTEIN; METAL TRANSPORT, MEMBRANE PROTEIN
Experimental Method methodX-RAY DIFFRACTION
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3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

2aem__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

2aem__assembly_1__model_1 | I(q)

10-2 10-1 105 106 107 q (1/Angstrom) I(q)
100 plotted points; both axes use logarithmic scales.

2aem__assembly_1__model_1 | P(r) · Pending

The new assembly/model P(r) has not been calculated yet This placeholder does not display legacy data r (Angstrom) P(r)
P(r) will be calculated and displayed separately for the same assembly/model.
Rg（Guinier）23.90 Å
Rg (electron density)22.90 Å
Total Rg23.65 Å
Atom count3474
Residues452
Excluded volume61751 ų
Maximum q0.500 Å⁻¹
Assembly Model Structure unit Oligomeric description Status CRYSOL Actions
1 1 2aem__assembly_1__model_1 dimeric （2） Success 4.1.3-1-20251215 (887e7ef) View Download
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4. Crystallography and Experiment 4. Crystallography & Experiment

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5. Entities and Polymers Entities & Polymers (2)

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6. Fold Classification (SCOP + CATH) 6 domains

SCOP 2.08 (3 domains)

Domain ID domain_idd2aema1
Class classc — Alpha and beta proteins (a/b)
Fold Fold foldc.2 — NAD(P)-binding Rossmann-fold domains
Superfamily Superfamily superfamilyc.2.1 — NAD(P)-binding Rossmann-fold domains
Family Family familyc.2.1.9 — Potassium channel NAD-binding domain
Domain ID domain_idd2aema2
Class classd — Alpha and beta proteins (a+b)
Fold Fold foldd.286 — TrkA C-terminal domain-like
Superfamily Superfamily superfamilyd.286.1 — TrkA C-terminal domain-like
Family Family familyd.286.1.1 — TrkA C-terminal domain-like
Domain ID domain_idd2aema3
Class classl — Artifacts
Fold Fold foldl.1 — Tags
Superfamily Superfamily superfamilyl.1.1 — Tags
Family Family familyl.1.1.1 — Tags

CATH v4.4 (3 domains)

Domain ID domain_id2aemA01
Class class3 — Alpha Beta
Architecture architecture40 — 3-Layer(aba) Sandwich
Topology topology50 — Rossmann fold
Homologous superfamily homologous superfamily720 — NAD(P)-binding Rossmann-like Domain
Domain ID domain_id2aemA02
Class class1 — Mainly Alpha
Architecture architecture20 — Up-down Bundle
Topology topology5 — Single alpha-helices involved in coiled-coils or other helix-helix interfaces
Homologous superfamily homologous superfamily870 — Voltage-gated potassium channel
Domain ID domain_id2aemA03
Class class3 — Alpha Beta
Architecture architecture30 — 2-Layer Sandwich
Topology topology70 — Alpha-Beta Plaits
Homologous superfamily homologous superfamily1450 — Regulator of K+ conductance, C-terminal domain
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7. Citations (2)