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2bez

Structure of a proteolitically resistant core from the severe acute respiratory syndrome coronavirus S2 fusion protein

Method: X-RAY DIFFRACTION
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1. Protein Identity and Related Structures Protein Identity & Related Structures

Spike glycoprotein

Human SARS coronavirus

UniProt P59594

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein homooligomer Homooligomer Protein 6 GLYCEROL × 3 water × 6 Consistent with protein count

Other States of the Same Protein in the Database

Monomer
1wyy 2rum 2run 2ruo 5xjk

5 assemblies

Homodimer
1zva 2ghv

2 assemblies

Homotetramer
1zv7

1 assemblies

Other homooligomers
1wnc 1wnc 1wnc 1wyy 1wyy 1zv8 1zv8 1zvb 2beq 2bez 2fxp 5wrg

22 assemblies; showing the first 12

Heteromeric or nucleic-acid complex
2ajf 2ajf 2dd8 2dd8 2ghw 2ghw 3bgf 3bgf 3d0g 3d0h 3d0h 3d0h

69 assemblies; showing the first 12

View Construct and Data Evidence
UniProt name SPIKE_CVHSA
Isoform —
PDB entities 1, 2
Chains and sequence ranges Author chain C； PDBConstruct 1–77； UniProt 896–972 Author chain F； PDBConstruct 1–42； UniProt 1142–1183

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

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2. Structure Basics 2. Structure Basics

Entry ID entry_id2bez
Deposition date deposition_date2004-12-02
Structure title titleStructure of a proteolitically resistant core from the severe acute respiratory syndrome coronavirus S2 fusion protein
Keywords keywordsCOILED COIL, MEMBRANE FUSION, SEVERE ACUTE RESPIRATORY SYNDROME, VIRAL PROTEIN; VIRAL PROTEIN
Experimental Method methodX-RAY DIFFRACTION
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3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

2bez__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

2bez__assembly_1__model_1 | I(q)

10-2 10-1 105 106 107 q (1/Angstrom) I(q)
100 plotted points; both axes use logarithmic scales.

2bez__assembly_1__model_1 | P(r) · Pending

The new assembly/model P(r) has not been calculated yet This placeholder does not display legacy data r (Angstrom) P(r)
P(r) will be calculated and displayed separately for the same assembly/model.
Rg（Guinier）30.65 Å
Rg (electron density)31.21 Å
Total Rg31.02 Å
Atom count2565
Residues357
Excluded volume45141 ų
Maximum q0.500 Å⁻¹
Assembly Model Structure unit Oligomeric description Status CRYSOL Actions
1 1 2bez__assembly_1__model_1 hexameric （6） Success 4.1.3-1-20251215 (887e7ef) View Download
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4. Crystallography and Experiment 4. Crystallography & Experiment

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5. Entities and Polymers Entities & Polymers (4)

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6. Fold Classification (SCOP + CATH) 3 domains

SCOP 2.08 (1 domains)

Domain ID domain_idd2bez.1
Class classh — Coiled coil proteins
Fold Fold foldh.3 — Stalk segment of viral fusion proteins
Superfamily Superfamily superfamilyh.3.3 — Coronavirus S2 glycoprotein
Family Family familyh.3.3.1 — Coronavirus spike glycoprotein S2 fragments

CATH v4.4 (2 domains)

Domain ID domain_id2bezC00
Class class1 — Mainly Alpha
Architecture architecture20 — Up-down Bundle
Topology topology5 — Single alpha-helices involved in coiled-coils or other helix-helix interfaces
Homologous superfamily homologous superfamily300 —
Domain ID domain_id2bezF00
Class class1 — Mainly Alpha
Architecture architecture20 — Up-down Bundle
Topology topology5 — Single alpha-helices involved in coiled-coils or other helix-helix interfaces
Homologous superfamily homologous superfamily790 — Single helix bin
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7. Citations (1)