2cfq

Sugar Free Lactose Permease at neutral pH

Method: X-RAY DIFFRACTION
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1. Protein Identity and Related Structures Protein Identity & Related Structures

LACTOSE PERMEASE

ESCHERICHIA COLI

UniProt P02920

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein monomer Monomer Protein 1 MERCURY (II) ION × 5 Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name LACY_ECOLI
Isoform —
PDB entities 1
Chains and sequence ranges Author chain A; PDBConstruct 1–417; UniProt 1–417

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

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2. Structure Basics 2. Structure Basics

Entry ID entry_id2cfq
Deposition date deposition_date2006-02-22
Structure title titleSugar Free Lactose Permease at neutral pH
Keywords keywordsTRANSPORT, LACTOSE PERMEASE, TRANSPORT MECHANISM, LACTOSE/H+ SYMPORT, SUGAR TRANSPORT, TRANSMEMBRANE, FORMYLATION; TRANSPORT
Experimental Method methodX-RAY DIFFRACTION
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3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

2cfq__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

2cfq__assembly_1__model_1 | I(q)

10-2 10-1 105 106 107 q (1/Angstrom) I(q)
100 plotted points; both axes use logarithmic scales.

2cfq__assembly_1__model_1 | P(r) · Pending

The new assembly/model P(r) has not been calculated yet This placeholder does not display legacy data r (Angstrom) P(r)
P(r) will be calculated and displayed separately for the same assembly/model.
Rg(Guinier)22.25 Å
Rg (electron density)21.59 Å
Total Rg22.32 Å
Atom count3295
Residues417
Excluded volume60627 ų
Maximum q0.500 Å⁻¹
Assembly Model Structure unit Oligomeric description Status CRYSOL Actions
1 1 2cfq__assembly_1__model_1 monomeric (1) Success 4.1.3-1-20251215 (887e7ef) View Download
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4. Crystallography and Experiment 4. Crystallography & Experiment

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5. Entities and Polymers Entities & Polymers (2)

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6. Fold Classification (SCOP + CATH) 3 domains

SCOP 2.08 (1 domains)

Domain ID domain_idd2cfqa_
Class classf — Membrane and cell surface proteins and peptides
Fold Fold foldf.38 — MFS general substrate transporter
Superfamily Superfamily superfamilyf.38.1 — MFS general substrate transporter
Family Family familyf.38.1.2 — LacY-like proton/sugar symporter

CATH v4.4 (2 domains)

Domain ID domain_id2cfqA01
Class class1 — Mainly Alpha
Architecture architecture20 — Up-down Bundle
Topology topology1250 — Growth Hormone; Chain: A;
Homologous superfamily homologous superfamily20 — MFS general substrate transporter like domains
Domain ID domain_id2cfqA02
Class class1 — Mainly Alpha
Architecture architecture20 — Up-down Bundle
Topology topology1250 — Growth Hormone; Chain: A;
Homologous superfamily homologous superfamily20 — MFS general substrate transporter like domains
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7. Citations (1)