2h1l

The Structure of the Oncoprotein SV40 Large T Antigen and p53 Tumor Suppressor Complex

Method: X-RAY DIFFRACTION Dmax: 222.0 Å Quality: GOOD

1. 蛋白身份与相关结构 Protein Identity & Related Structures

Large T antigen

Simian virus 40

UniProt Q9DH70

当前结构中的状态

Assembly 聚集状态 构建体 突变与修饰 配体、离子与共同组分 实验方法与环境 结构质量
1 蛋白异源复合物 异源复合物 蛋白 × 12 PDB 声明:dodecameric(12) 与蛋白拷贝数一致 链 A; UniProt 260–627 链 B; UniProt 260–627 链 C; UniProt 260–627 链 D; UniProt 260–627 链 E; UniProt 260–627 链 F; UniProt 260–627 片段:Helicase Domain, residues 260-627 Cellular tumor antigen p53 × 6 (Q9NP68) ZN ZINC ION × 12 X-RAY DIFFRACTION X-ray结晶条件:VAPOR DIFFUSION;pH 6.5;298 K;5.4% PEG 4000, 73mM Mops Buffer, 22mM Lithium Sulfate, pH 6.5, VAPOR DIFFUSION, temperature 298K 分辨率 3.16 Å R-free 0.308
2 蛋白异源复合物 异源复合物 蛋白 × 12 PDB 声明:dodecameric(12) 与蛋白拷贝数一致 链 G; UniProt 260–627 链 H; UniProt 260–627 链 I; UniProt 260–627 链 J; UniProt 260–627 链 K; UniProt 260–627 链 L; UniProt 260–627 片段:Helicase Domain, residues 260-627 Cellular tumor antigen p53 × 6 (Q9NP68) ZN ZINC ION × 12 X-RAY DIFFRACTION X-ray结晶条件:VAPOR DIFFUSION;pH 6.5;298 K;5.4% PEG 4000, 73mM Mops Buffer, 22mM Lithium Sulfate, pH 6.5, VAPOR DIFFUSION, temperature 298K 分辨率 3.16 Å R-free 0.308

数据库中的同蛋白其他状态

以下每一行都是同一 UniProt 蛋白在另一个 PDB 条目中的 biological assembly, “相对当前条目”直接指出证据层面的不同;没有差异标签表示当前已读取字段一致。

共 2 个其他 PDB 条目、4 个 assembly。 打开独立比较页并筛选聚集状态

查看构建体与数据证据
UniProt名称 Q9DH70_SV40
Isoform
PDB实体 1
链与序列区间 作者链 A; PDB构建体 3–370; UniProt 260–627 作者链 B; PDB构建体 3–370; UniProt 260–627 作者链 C; PDB构建体 3–370; UniProt 260–627 作者链 D; PDB构建体 3–370; UniProt 260–627 作者链 E; PDB构建体 3–370; UniProt 260–627 作者链 F; PDB构建体 3–370; UniProt 260–627 作者链 G; PDB构建体 3–370; UniProt 260–627 作者链 H; PDB构建体 3–370; UniProt 260–627 作者链 I; PDB构建体 3–370; UniProt 260–627 作者链 J; PDB构建体 3–370; UniProt 260–627 作者链 K; PDB构建体 3–370; UniProt 260–627 作者链 L; PDB构建体 3–370; UniProt 260–627

Cellular tumor antigen p53

Homo sapiens

UniProt Q9NP68

当前结构中的状态

Assembly 聚集状态 构建体 突变与修饰 配体、离子与共同组分 实验方法与环境 结构质量
1 蛋白异源复合物 异源复合物 蛋白 × 12 PDB 声明:dodecameric(12) 与蛋白拷贝数一致 链 M; UniProt 92–292 链 N; UniProt 92–292 链 O; UniProt 92–292 链 P; UniProt 92–292 链 Q; UniProt 92–292 链 R; UniProt 92–292 片段:DNA Binding Domain, residues 92-292 Large T antigen × 6 (Q9DH70) ZN ZINC ION × 12 X-RAY DIFFRACTION X-ray结晶条件:VAPOR DIFFUSION;pH 6.5;298 K;5.4% PEG 4000, 73mM Mops Buffer, 22mM Lithium Sulfate, pH 6.5, VAPOR DIFFUSION, temperature 298K 分辨率 3.16 Å R-free 0.308
2 蛋白异源复合物 异源复合物 蛋白 × 12 PDB 声明:dodecameric(12) 与蛋白拷贝数一致 链 S; UniProt 92–292 链 T; UniProt 92–292 链 U; UniProt 92–292 链 V; UniProt 92–292 链 W; UniProt 92–292 链 X; UniProt 92–292 片段:DNA Binding Domain, residues 92-292 Large T antigen × 6 (Q9DH70) ZN ZINC ION × 12 X-RAY DIFFRACTION X-ray结晶条件:VAPOR DIFFUSION;pH 6.5;298 K;5.4% PEG 4000, 73mM Mops Buffer, 22mM Lithium Sulfate, pH 6.5, VAPOR DIFFUSION, temperature 298K 分辨率 3.16 Å R-free 0.308

数据库中的同蛋白其他状态

以下每一行都是同一 UniProt 蛋白在另一个 PDB 条目中的 biological assembly, “相对当前条目”直接指出证据层面的不同;没有差异标签表示当前已读取字段一致。

共 5 个其他 PDB 条目、5 个 assembly。 打开独立比较页并筛选聚集状态

查看构建体与数据证据
UniProt名称 P53_HUMAN
Isoform
PDB实体 2
链与序列区间 作者链 M; PDB构建体 3–203; UniProt 92–292 作者链 N; PDB构建体 3–203; UniProt 92–292 作者链 O; PDB构建体 3–203; UniProt 92–292 作者链 P; PDB构建体 3–203; UniProt 92–292 作者链 Q; PDB构建体 3–203; UniProt 92–292 作者链 R; PDB构建体 3–203; UniProt 92–292 作者链 S; PDB构建体 3–203; UniProt 92–292 作者链 T; PDB构建体 3–203; UniProt 92–292 作者链 U; PDB构建体 3–203; UniProt 92–292 作者链 V; PDB构建体 3–203; UniProt 92–292 作者链 W; PDB构建体 3–203; UniProt 92–292 作者链 X; PDB构建体 3–203; UniProt 92–292

页面优先展示蛋白身份、当前 assembly、共同组分、聚集状态和跨 PDB 结构链接。 链映射与序列区间收在“数据证据”中;数据库内部编号、导入时间和 assembly 操作表达式仅用于维护,因此不在读者页面展示。

SAXS 散射曲线 SAXS Profile

SAXS profile for 2h1l

P(r) 距离分布 P(r) Distribution

P(r) distribution for 2h1l
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2. 结构基本信息 2. Structure Basics

条目编号 entry_id2h1l
沉积日期 deposition_date2006-05-16
结构标题 titleThe Structure of the Oncoprotein SV40 Large T Antigen and p53 Tumor Suppressor Complex
关键词 keywordsp53 Loop-3 conformation change, VIRAL PROTEIN; VIRAL PROTEIN
实验方法 methodX-RAY DIFFRACTION

3. SAXS 参数 (CRYSOL 理论计算) 3. SAXS Parameters (CRYSOL)

回转半径 Rg (Guinier) rg_guinier89.67
回转半径 Rg (电子) rg_electron89.16
零角强度 I(0) i08137490000.00
分子量 molecular_weight770560.0 kDa
排除体积 excluded_volume964490 ų
包络体积 envelope_volume1674100 ų
水化壳体积 shell_volume151300 ų
包络直径 envelope_diameter295.1
壳层 Rg shell_rg98.84
包络 Rg envelope_rg84.01
形状 Rg shape_rg89.16
总 Rg total_rg89.22
总原子数 total_atoms53920
残基数 n_residues6736
球谐函数阶数 n_harmonics20
q 范围 q_range— – 0.5000 −1
数据点数 n_points101
壳层类型 shell_typedirectional
溶剂电子密度 solvent_density0.3340 e/ų
壳层衬度 contrast_shell0.0300 e/ų
CRYSOL 版本 crysol_version4.1.3

4. P(r) 距离分布 (GNOM 反演) 4. P(r) Analysis (GNOM)

最大尺寸 Dmax dmax222.0
Rg (实空间) rg_real86.60
Rg 误差 (实空间) rg_real_error0.70
I(0) (实空间) i0_real7.8790e+09
I(0) 误差 (实空间) i0_real_error1.5830e+08
Rg (倒空间) rg_reciprocal88.65
I(0) (倒空间) i0_reciprocal8110000000.0000
解质量估计 total_estimate0.8554
解质量评级 solution_quality GOOD a GOOD solution
P(r) 峰数 n_peaks2
主峰位置 r_peak_primary143.7
偏度 Skewness skewness0.007
峰度 Kurtosis kurtosis-1.050
角度范围 angular_range— – 0.0850 −1
当前正则化参数 α current_alpha0.3106
最高正则化参数 α highest_alpha462100000.0000
实空间数据点数 n_real_points18
GNOM 版本 gnom_version4.1.3
质量判据 quality_criteria AN1: 0.001; Oscil: 0.945; Stabil: 0.977; Sysdev: 1.000; Positv: 1.000; Valcen: 0.566; Smooth: 0.000

5. 晶体学与实验 5. Crystallography & Experiment

6. 实体与聚合物信息 Entities & Polymers (3)

7. 折叠分类 (SCOP + CATH) 84 domains

SCOP 2.08 (36 domains)

结构域编号 domain_idd2h1la_
类 Class classc — Alpha and beta proteins (a/b)
折叠类型 Fold foldc.37 — P-loop containing nucleoside triphosphate hydrolases
超家族 Superfamily superfamilyc.37.1 — P-loop containing nucleoside triphosphate hydrolases
家族 Family familyc.37.1.20 — Extended AAA-ATPase domain
结构域编号 domain_idd2h1lb_
类 Class classc — Alpha and beta proteins (a/b)
折叠类型 Fold foldc.37 — P-loop containing nucleoside triphosphate hydrolases
超家族 Superfamily superfamilyc.37.1 — P-loop containing nucleoside triphosphate hydrolases
家族 Family familyc.37.1.20 — Extended AAA-ATPase domain
结构域编号 domain_idd2h1lc_
类 Class classc — Alpha and beta proteins (a/b)
折叠类型 Fold foldc.37 — P-loop containing nucleoside triphosphate hydrolases
超家族 Superfamily superfamilyc.37.1 — P-loop containing nucleoside triphosphate hydrolases
家族 Family familyc.37.1.20 — Extended AAA-ATPase domain
结构域编号 domain_idd2h1ld_
类 Class classc — Alpha and beta proteins (a/b)
折叠类型 Fold foldc.37 — P-loop containing nucleoside triphosphate hydrolases
超家族 Superfamily superfamilyc.37.1 — P-loop containing nucleoside triphosphate hydrolases
家族 Family familyc.37.1.20 — Extended AAA-ATPase domain
结构域编号 domain_idd2h1le_
类 Class classc — Alpha and beta proteins (a/b)
折叠类型 Fold foldc.37 — P-loop containing nucleoside triphosphate hydrolases
超家族 Superfamily superfamilyc.37.1 — P-loop containing nucleoside triphosphate hydrolases
家族 Family familyc.37.1.20 — Extended AAA-ATPase domain
结构域编号 domain_idd2h1lf_
类 Class classc — Alpha and beta proteins (a/b)
折叠类型 Fold foldc.37 — P-loop containing nucleoside triphosphate hydrolases
超家族 Superfamily superfamilyc.37.1 — P-loop containing nucleoside triphosphate hydrolases
家族 Family familyc.37.1.20 — Extended AAA-ATPase domain
结构域编号 domain_idd2h1lg_
类 Class classc — Alpha and beta proteins (a/b)
折叠类型 Fold foldc.37 — P-loop containing nucleoside triphosphate hydrolases
超家族 Superfamily superfamilyc.37.1 — P-loop containing nucleoside triphosphate hydrolases
家族 Family familyc.37.1.20 — Extended AAA-ATPase domain
结构域编号 domain_idd2h1lh_
类 Class classc — Alpha and beta proteins (a/b)
折叠类型 Fold foldc.37 — P-loop containing nucleoside triphosphate hydrolases
超家族 Superfamily superfamilyc.37.1 — P-loop containing nucleoside triphosphate hydrolases
家族 Family familyc.37.1.20 — Extended AAA-ATPase domain
结构域编号 domain_idd2h1li_
类 Class classc — Alpha and beta proteins (a/b)
折叠类型 Fold foldc.37 — P-loop containing nucleoside triphosphate hydrolases
超家族 Superfamily superfamilyc.37.1 — P-loop containing nucleoside triphosphate hydrolases
家族 Family familyc.37.1.20 — Extended AAA-ATPase domain
结构域编号 domain_idd2h1lj_
类 Class classc — Alpha and beta proteins (a/b)
折叠类型 Fold foldc.37 — P-loop containing nucleoside triphosphate hydrolases
超家族 Superfamily superfamilyc.37.1 — P-loop containing nucleoside triphosphate hydrolases
家族 Family familyc.37.1.20 — Extended AAA-ATPase domain
结构域编号 domain_idd2h1lk_
类 Class classc — Alpha and beta proteins (a/b)
折叠类型 Fold foldc.37 — P-loop containing nucleoside triphosphate hydrolases
超家族 Superfamily superfamilyc.37.1 — P-loop containing nucleoside triphosphate hydrolases
家族 Family familyc.37.1.20 — Extended AAA-ATPase domain
结构域编号 domain_idd2h1ll_
类 Class classc — Alpha and beta proteins (a/b)
折叠类型 Fold foldc.37 — P-loop containing nucleoside triphosphate hydrolases
超家族 Superfamily superfamilyc.37.1 — P-loop containing nucleoside triphosphate hydrolases
家族 Family familyc.37.1.20 — Extended AAA-ATPase domain
结构域编号 domain_idd2h1lm2
类 Class classb — All beta proteins
折叠类型 Fold foldb.2 — Common fold of diphtheria toxin/transcription factors/cytochrome f
超家族 Superfamily superfamilyb.2.5 — p53-like transcription factors
家族 Family familyb.2.5.2 — p53 DNA-binding domain-like
结构域编号 domain_idd2h1lm3
类 Class classl — Artifacts
折叠类型 Fold foldl.1 — Tags
超家族 Superfamily superfamilyl.1.1 — Tags
家族 Family familyl.1.1.1 — Tags
结构域编号 domain_idd2h1ln2
类 Class classb — All beta proteins
折叠类型 Fold foldb.2 — Common fold of diphtheria toxin/transcription factors/cytochrome f
超家族 Superfamily superfamilyb.2.5 — p53-like transcription factors
家族 Family familyb.2.5.2 — p53 DNA-binding domain-like
结构域编号 domain_idd2h1ln3
类 Class classl — Artifacts
折叠类型 Fold foldl.1 — Tags
超家族 Superfamily superfamilyl.1.1 — Tags
家族 Family familyl.1.1.1 — Tags
结构域编号 domain_idd2h1lo2
类 Class classb — All beta proteins
折叠类型 Fold foldb.2 — Common fold of diphtheria toxin/transcription factors/cytochrome f
超家族 Superfamily superfamilyb.2.5 — p53-like transcription factors
家族 Family familyb.2.5.2 — p53 DNA-binding domain-like
结构域编号 domain_idd2h1lo3
类 Class classl — Artifacts
折叠类型 Fold foldl.1 — Tags
超家族 Superfamily superfamilyl.1.1 — Tags
家族 Family familyl.1.1.1 — Tags
结构域编号 domain_idd2h1lp2
类 Class classb — All beta proteins
折叠类型 Fold foldb.2 — Common fold of diphtheria toxin/transcription factors/cytochrome f
超家族 Superfamily superfamilyb.2.5 — p53-like transcription factors
家族 Family familyb.2.5.2 — p53 DNA-binding domain-like
结构域编号 domain_idd2h1lp3
类 Class classl — Artifacts
折叠类型 Fold foldl.1 — Tags
超家族 Superfamily superfamilyl.1.1 — Tags
家族 Family familyl.1.1.1 — Tags
结构域编号 domain_idd2h1lq2
类 Class classb — All beta proteins
折叠类型 Fold foldb.2 — Common fold of diphtheria toxin/transcription factors/cytochrome f
超家族 Superfamily superfamilyb.2.5 — p53-like transcription factors
家族 Family familyb.2.5.2 — p53 DNA-binding domain-like
结构域编号 domain_idd2h1lq3
类 Class classl — Artifacts
折叠类型 Fold foldl.1 — Tags
超家族 Superfamily superfamilyl.1.1 — Tags
家族 Family familyl.1.1.1 — Tags
结构域编号 domain_idd2h1lr2
类 Class classb — All beta proteins
折叠类型 Fold foldb.2 — Common fold of diphtheria toxin/transcription factors/cytochrome f
超家族 Superfamily superfamilyb.2.5 — p53-like transcription factors
家族 Family familyb.2.5.2 — p53 DNA-binding domain-like
结构域编号 domain_idd2h1lr3
类 Class classl — Artifacts
折叠类型 Fold foldl.1 — Tags
超家族 Superfamily superfamilyl.1.1 — Tags
家族 Family familyl.1.1.1 — Tags
结构域编号 domain_idd2h1ls2
类 Class classb — All beta proteins
折叠类型 Fold foldb.2 — Common fold of diphtheria toxin/transcription factors/cytochrome f
超家族 Superfamily superfamilyb.2.5 — p53-like transcription factors
家族 Family familyb.2.5.2 — p53 DNA-binding domain-like
结构域编号 domain_idd2h1ls3
类 Class classl — Artifacts
折叠类型 Fold foldl.1 — Tags
超家族 Superfamily superfamilyl.1.1 — Tags
家族 Family familyl.1.1.1 — Tags
结构域编号 domain_idd2h1lt2
类 Class classb — All beta proteins
折叠类型 Fold foldb.2 — Common fold of diphtheria toxin/transcription factors/cytochrome f
超家族 Superfamily superfamilyb.2.5 — p53-like transcription factors
家族 Family familyb.2.5.2 — p53 DNA-binding domain-like
结构域编号 domain_idd2h1lt3
类 Class classl — Artifacts
折叠类型 Fold foldl.1 — Tags
超家族 Superfamily superfamilyl.1.1 — Tags
家族 Family familyl.1.1.1 — Tags
结构域编号 domain_idd2h1lu2
类 Class classb — All beta proteins
折叠类型 Fold foldb.2 — Common fold of diphtheria toxin/transcription factors/cytochrome f
超家族 Superfamily superfamilyb.2.5 — p53-like transcription factors
家族 Family familyb.2.5.2 — p53 DNA-binding domain-like
结构域编号 domain_idd2h1lu3
类 Class classl — Artifacts
折叠类型 Fold foldl.1 — Tags
超家族 Superfamily superfamilyl.1.1 — Tags
家族 Family familyl.1.1.1 — Tags
结构域编号 domain_idd2h1lv2
类 Class classb — All beta proteins
折叠类型 Fold foldb.2 — Common fold of diphtheria toxin/transcription factors/cytochrome f
超家族 Superfamily superfamilyb.2.5 — p53-like transcription factors
家族 Family familyb.2.5.2 — p53 DNA-binding domain-like
结构域编号 domain_idd2h1lv3
类 Class classl — Artifacts
折叠类型 Fold foldl.1 — Tags
超家族 Superfamily superfamilyl.1.1 — Tags
家族 Family familyl.1.1.1 — Tags
结构域编号 domain_idd2h1lw2
类 Class classb — All beta proteins
折叠类型 Fold foldb.2 — Common fold of diphtheria toxin/transcription factors/cytochrome f
超家族 Superfamily superfamilyb.2.5 — p53-like transcription factors
家族 Family familyb.2.5.2 — p53 DNA-binding domain-like
结构域编号 domain_idd2h1lw3
类 Class classl — Artifacts
折叠类型 Fold foldl.1 — Tags
超家族 Superfamily superfamilyl.1.1 — Tags
家族 Family familyl.1.1.1 — Tags
结构域编号 domain_idd2h1lx2
类 Class classb — All beta proteins
折叠类型 Fold foldb.2 — Common fold of diphtheria toxin/transcription factors/cytochrome f
超家族 Superfamily superfamilyb.2.5 — p53-like transcription factors
家族 Family familyb.2.5.2 — p53 DNA-binding domain-like
结构域编号 domain_idd2h1lx3
类 Class classl — Artifacts
折叠类型 Fold foldl.1 — Tags
超家族 Superfamily superfamilyl.1.1 — Tags
家族 Family familyl.1.1.1 — Tags

CATH v4.4 (48 domains)

结构域编号 domain_id2h1lA01
类 Class class1 — Mainly Alpha
架构 Architecture architecture10 — Orthogonal Bundle
拓扑 Topology topology10 — Arc Repressor Mutant, subunit A
同源超家族 H-superfamily homologous superfamily510 — Zinc finger, large T-antigen D1 domain
结构域编号 domain_id2h1lA02
类 Class class1 — Mainly Alpha
架构 Architecture architecture20 — Up-down Bundle
拓扑 Topology topology1050 — Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2
同源超家族 H-superfamily homologous superfamily70 — Large T antigen, SV40, domain 3
结构域编号 domain_id2h1lA03
类 Class class3 — Alpha Beta
架构 Architecture architecture40 — 3-Layer(aba) Sandwich
拓扑 Topology topology50 — Rossmann fold
同源超家族 H-superfamily homologous superfamily300 — P-loop containing nucleotide triphosphate hydrolases
结构域编号 domain_id2h1lB01
类 Class class1 — Mainly Alpha
架构 Architecture architecture10 — Orthogonal Bundle
拓扑 Topology topology10 — Arc Repressor Mutant, subunit A
同源超家族 H-superfamily homologous superfamily510 — Zinc finger, large T-antigen D1 domain
结构域编号 domain_id2h1lB02
类 Class class1 — Mainly Alpha
架构 Architecture architecture20 — Up-down Bundle
拓扑 Topology topology1050 — Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2
同源超家族 H-superfamily homologous superfamily70 — Large T antigen, SV40, domain 3
结构域编号 domain_id2h1lB03
类 Class class3 — Alpha Beta
架构 Architecture architecture40 — 3-Layer(aba) Sandwich
拓扑 Topology topology50 — Rossmann fold
同源超家族 H-superfamily homologous superfamily300 — P-loop containing nucleotide triphosphate hydrolases
结构域编号 domain_id2h1lC01
类 Class class1 — Mainly Alpha
架构 Architecture architecture10 — Orthogonal Bundle
拓扑 Topology topology10 — Arc Repressor Mutant, subunit A
同源超家族 H-superfamily homologous superfamily510 — Zinc finger, large T-antigen D1 domain
结构域编号 domain_id2h1lC02
类 Class class1 — Mainly Alpha
架构 Architecture architecture20 — Up-down Bundle
拓扑 Topology topology1050 — Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2
同源超家族 H-superfamily homologous superfamily70 — Large T antigen, SV40, domain 3
结构域编号 domain_id2h1lC03
类 Class class3 — Alpha Beta
架构 Architecture architecture40 — 3-Layer(aba) Sandwich
拓扑 Topology topology50 — Rossmann fold
同源超家族 H-superfamily homologous superfamily300 — P-loop containing nucleotide triphosphate hydrolases
结构域编号 domain_id2h1lD01
类 Class class1 — Mainly Alpha
架构 Architecture architecture10 — Orthogonal Bundle
拓扑 Topology topology10 — Arc Repressor Mutant, subunit A
同源超家族 H-superfamily homologous superfamily510 — Zinc finger, large T-antigen D1 domain
结构域编号 domain_id2h1lD02
类 Class class1 — Mainly Alpha
架构 Architecture architecture20 — Up-down Bundle
拓扑 Topology topology1050 — Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2
同源超家族 H-superfamily homologous superfamily70 — Large T antigen, SV40, domain 3
结构域编号 domain_id2h1lD03
类 Class class3 — Alpha Beta
架构 Architecture architecture40 — 3-Layer(aba) Sandwich
拓扑 Topology topology50 — Rossmann fold
同源超家族 H-superfamily homologous superfamily300 — P-loop containing nucleotide triphosphate hydrolases
结构域编号 domain_id2h1lE01
类 Class class1 — Mainly Alpha
架构 Architecture architecture10 — Orthogonal Bundle
拓扑 Topology topology10 — Arc Repressor Mutant, subunit A
同源超家族 H-superfamily homologous superfamily510 — Zinc finger, large T-antigen D1 domain
结构域编号 domain_id2h1lE02
类 Class class1 — Mainly Alpha
架构 Architecture architecture20 — Up-down Bundle
拓扑 Topology topology1050 — Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2
同源超家族 H-superfamily homologous superfamily70 — Large T antigen, SV40, domain 3
结构域编号 domain_id2h1lE03
类 Class class3 — Alpha Beta
架构 Architecture architecture40 — 3-Layer(aba) Sandwich
拓扑 Topology topology50 — Rossmann fold
同源超家族 H-superfamily homologous superfamily300 — P-loop containing nucleotide triphosphate hydrolases
结构域编号 domain_id2h1lF01
类 Class class1 — Mainly Alpha
架构 Architecture architecture10 — Orthogonal Bundle
拓扑 Topology topology10 — Arc Repressor Mutant, subunit A
同源超家族 H-superfamily homologous superfamily510 — Zinc finger, large T-antigen D1 domain
结构域编号 domain_id2h1lF02
类 Class class1 — Mainly Alpha
架构 Architecture architecture20 — Up-down Bundle
拓扑 Topology topology1050 — Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2
同源超家族 H-superfamily homologous superfamily70 — Large T antigen, SV40, domain 3
结构域编号 domain_id2h1lF03
类 Class class3 — Alpha Beta
架构 Architecture architecture40 — 3-Layer(aba) Sandwich
拓扑 Topology topology50 — Rossmann fold
同源超家族 H-superfamily homologous superfamily300 — P-loop containing nucleotide triphosphate hydrolases
结构域编号 domain_id2h1lG01
类 Class class1 — Mainly Alpha
架构 Architecture architecture10 — Orthogonal Bundle
拓扑 Topology topology10 — Arc Repressor Mutant, subunit A
同源超家族 H-superfamily homologous superfamily510 — Zinc finger, large T-antigen D1 domain
结构域编号 domain_id2h1lG02
类 Class class1 — Mainly Alpha
架构 Architecture architecture20 — Up-down Bundle
拓扑 Topology topology1050 — Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2
同源超家族 H-superfamily homologous superfamily70 — Large T antigen, SV40, domain 3
结构域编号 domain_id2h1lG03
类 Class class3 — Alpha Beta
架构 Architecture architecture40 — 3-Layer(aba) Sandwich
拓扑 Topology topology50 — Rossmann fold
同源超家族 H-superfamily homologous superfamily300 — P-loop containing nucleotide triphosphate hydrolases
结构域编号 domain_id2h1lH01
类 Class class1 — Mainly Alpha
架构 Architecture architecture10 — Orthogonal Bundle
拓扑 Topology topology10 — Arc Repressor Mutant, subunit A
同源超家族 H-superfamily homologous superfamily510 — Zinc finger, large T-antigen D1 domain
结构域编号 domain_id2h1lH02
类 Class class1 — Mainly Alpha
架构 Architecture architecture20 — Up-down Bundle
拓扑 Topology topology1050 — Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2
同源超家族 H-superfamily homologous superfamily70 — Large T antigen, SV40, domain 3
结构域编号 domain_id2h1lH03
类 Class class3 — Alpha Beta
架构 Architecture architecture40 — 3-Layer(aba) Sandwich
拓扑 Topology topology50 — Rossmann fold
同源超家族 H-superfamily homologous superfamily300 — P-loop containing nucleotide triphosphate hydrolases
结构域编号 domain_id2h1lI01
类 Class class1 — Mainly Alpha
架构 Architecture architecture10 — Orthogonal Bundle
拓扑 Topology topology10 — Arc Repressor Mutant, subunit A
同源超家族 H-superfamily homologous superfamily510 — Zinc finger, large T-antigen D1 domain
结构域编号 domain_id2h1lI02
类 Class class1 — Mainly Alpha
架构 Architecture architecture20 — Up-down Bundle
拓扑 Topology topology1050 — Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2
同源超家族 H-superfamily homologous superfamily70 — Large T antigen, SV40, domain 3
结构域编号 domain_id2h1lI03
类 Class class3 — Alpha Beta
架构 Architecture architecture40 — 3-Layer(aba) Sandwich
拓扑 Topology topology50 — Rossmann fold
同源超家族 H-superfamily homologous superfamily300 — P-loop containing nucleotide triphosphate hydrolases
结构域编号 domain_id2h1lJ01
类 Class class1 — Mainly Alpha
架构 Architecture architecture10 — Orthogonal Bundle
拓扑 Topology topology10 — Arc Repressor Mutant, subunit A
同源超家族 H-superfamily homologous superfamily510 — Zinc finger, large T-antigen D1 domain
结构域编号 domain_id2h1lJ02
类 Class class1 — Mainly Alpha
架构 Architecture architecture20 — Up-down Bundle
拓扑 Topology topology1050 — Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2
同源超家族 H-superfamily homologous superfamily70 — Large T antigen, SV40, domain 3
结构域编号 domain_id2h1lJ03
类 Class class3 — Alpha Beta
架构 Architecture architecture40 — 3-Layer(aba) Sandwich
拓扑 Topology topology50 — Rossmann fold
同源超家族 H-superfamily homologous superfamily300 — P-loop containing nucleotide triphosphate hydrolases
结构域编号 domain_id2h1lK01
类 Class class1 — Mainly Alpha
架构 Architecture architecture10 — Orthogonal Bundle
拓扑 Topology topology10 — Arc Repressor Mutant, subunit A
同源超家族 H-superfamily homologous superfamily510 — Zinc finger, large T-antigen D1 domain
结构域编号 domain_id2h1lK02
类 Class class1 — Mainly Alpha
架构 Architecture architecture20 — Up-down Bundle
拓扑 Topology topology1050 — Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2
同源超家族 H-superfamily homologous superfamily70 — Large T antigen, SV40, domain 3
结构域编号 domain_id2h1lK03
类 Class class3 — Alpha Beta
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拓扑 Topology topology50 — Rossmann fold
同源超家族 H-superfamily homologous superfamily300 — P-loop containing nucleotide triphosphate hydrolases
结构域编号 domain_id2h1lL01
类 Class class1 — Mainly Alpha
架构 Architecture architecture10 — Orthogonal Bundle
拓扑 Topology topology10 — Arc Repressor Mutant, subunit A
同源超家族 H-superfamily homologous superfamily510 — Zinc finger, large T-antigen D1 domain
结构域编号 domain_id2h1lL02
类 Class class1 — Mainly Alpha
架构 Architecture architecture20 — Up-down Bundle
拓扑 Topology topology1050 — Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2
同源超家族 H-superfamily homologous superfamily70 — Large T antigen, SV40, domain 3
结构域编号 domain_id2h1lL03
类 Class class3 — Alpha Beta
架构 Architecture architecture40 — 3-Layer(aba) Sandwich
拓扑 Topology topology50 — Rossmann fold
同源超家族 H-superfamily homologous superfamily300 — P-loop containing nucleotide triphosphate hydrolases
结构域编号 domain_id2h1lM00
类 Class class2 — Mainly Beta
架构 Architecture architecture60 — Sandwich
拓扑 Topology topology40 — Immunoglobulin-like
同源超家族 H-superfamily homologous superfamily720
结构域编号 domain_id2h1lN00
类 Class class2 — Mainly Beta
架构 Architecture architecture60 — Sandwich
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同源超家族 H-superfamily homologous superfamily720
结构域编号 domain_id2h1lO00
类 Class class2 — Mainly Beta
架构 Architecture architecture60 — Sandwich
拓扑 Topology topology40 — Immunoglobulin-like
同源超家族 H-superfamily homologous superfamily720
结构域编号 domain_id2h1lP00
类 Class class2 — Mainly Beta
架构 Architecture architecture60 — Sandwich
拓扑 Topology topology40 — Immunoglobulin-like
同源超家族 H-superfamily homologous superfamily720
结构域编号 domain_id2h1lQ00
类 Class class2 — Mainly Beta
架构 Architecture architecture60 — Sandwich
拓扑 Topology topology40 — Immunoglobulin-like
同源超家族 H-superfamily homologous superfamily720
结构域编号 domain_id2h1lR00
类 Class class2 — Mainly Beta
架构 Architecture architecture60 — Sandwich
拓扑 Topology topology40 — Immunoglobulin-like
同源超家族 H-superfamily homologous superfamily720
结构域编号 domain_id2h1lS00
类 Class class2 — Mainly Beta
架构 Architecture architecture60 — Sandwich
拓扑 Topology topology40 — Immunoglobulin-like
同源超家族 H-superfamily homologous superfamily720
结构域编号 domain_id2h1lT00
类 Class class2 — Mainly Beta
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同源超家族 H-superfamily homologous superfamily720
结构域编号 domain_id2h1lU00
类 Class class2 — Mainly Beta
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拓扑 Topology topology40 — Immunoglobulin-like
同源超家族 H-superfamily homologous superfamily720
结构域编号 domain_id2h1lV00
类 Class class2 — Mainly Beta
架构 Architecture architecture60 — Sandwich
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同源超家族 H-superfamily homologous superfamily720
结构域编号 domain_id2h1lW00
类 Class class2 — Mainly Beta
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同源超家族 H-superfamily homologous superfamily720
结构域编号 domain_id2h1lX00
类 Class class2 — Mainly Beta
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同源超家族 H-superfamily homologous superfamily720

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