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2h7e

Solution structure of the talin F3 domain in complex with a chimeric beta3 integrin-PIP kinase peptide- minimized average structure

Method: SOLUTION NMR
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1. Protein Identity and Related Structures Protein Identity & Related Structures

Talin-1

Gallus gallus

UniProt P54939

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Insufficient information Heteromer Protein 2 Chimera of 24-mer peptide from Integrin beta-3 and 10-mer peptide from Phosphatidylinositol-4-phosphate 5-kinase type-1 gamma × 1 （O70161,P05106） Consistent with protein count

Other States of the Same Protein in the Database

Monomer
1mix 2hrj

2 assemblies

Homodimer

None

Homotetramer

None

Other homooligomers

None

Heteromeric or nucleic-acid complex
1miz 1mk7 1mk7 1mk9 1mk9 1mk9 1mk9 1rkc 1zvz 2h7d 2h7e 2k00

13 assemblies; showing the first 12

View Construct and Data Evidence
UniProt name TLN1_CHICK
Isoform —
PDB entities 1
Chains and sequence ranges Author chain A； PDBConstruct 5–101； UniProt 309–405

Chimera of 24-mer peptide from Integrin beta-3 and 10-mer peptide from Phosphatidylinositol-4-phosphate 5-kinase type-1 gamma

OrganismNot specified

UniProt O70161

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Insufficient information Heteromer Protein 2 Talin-1 × 1 （P54939） Consistent with protein count

Other States of the Same Protein in the Database

Monomer

None

Homodimer

None

Homotetramer

None

Other homooligomers

None

Heteromeric or nucleic-acid complex
1y19 1y19 1y19 1y19 1y19 1y19 2h7d 2h7e

8 assemblies

View Construct and Data Evidence
UniProt name PI51C_MOUS
Isoform —
PDB entities 2
Chains and sequence ranges Author chain B； PDBConstruct 25–34； UniProt 643–652

Chimera of 24-mer peptide from Integrin beta-3 and 10-mer peptide from Phosphatidylinositol-4-phosphate 5-kinase type-1 gamma

OrganismNot specified

UniProt P05106

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Insufficient information Heteromer Protein 2 Talin-1 × 1 （P54939） Consistent with protein count

Other States of the Same Protein in the Database

Monomer
1s4x 2kv9 2l91 2ljd 2lje 2ljf 2rmz 2rn0

8 assemblies

Homodimer

None

Homotetramer

None

Other homooligomers

None

Heteromeric or nucleic-acid complex
1kup 1kuz 1l5g 1m1x 1m8o 1miz 1mk7 1mk7 1mk9 1mk9 1mk9 1mk9

169 assemblies; showing the first 12

View Construct and Data Evidence
UniProt name ITB3_HUMAN
Isoform —
PDB entities 2
Chains and sequence ranges Author chain B； PDBConstruct 1–24； UniProt 742–765

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

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2. Structure Basics 2. Structure Basics

Entry ID entry_id2h7e
Deposition date deposition_date2006-06-02
Structure title titleSolution structure of the talin F3 domain in complex with a chimeric beta3 integrin-PIP kinase peptide- minimized average structure
Keywords keywordsProtein-peptide complex, alpha helix, beta sheet, STRUCTURAL PROTEIN; STRUCTURAL PROTEIN
Experimental Method methodSOLUTION NMR
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3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

2h7e__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

2h7e__assembly_1__model_1 | I(q)

10-2 10-1 105 106 q (1/Angstrom) I(q)
100 plotted points; both axes use logarithmic scales.

2h7e__assembly_1__model_1 | P(r) · Pending

The new assembly/model P(r) has not been calculated yet This placeholder does not display legacy data r (Angstrom) P(r)
P(r) will be calculated and displayed separately for the same assembly/model.
Rg（Guinier）17.63 Å
Rg (electron density)16.80 Å
Total Rg18.25 Å
Atom count2255
Residues134
Excluded volume20049 ų
Maximum q0.500 Å⁻¹
Assembly Model Structure unit Oligomeric description Status CRYSOL Actions
1 1 2h7e__assembly_1__model_1 dimeric （2） Success 4.1.3-1-20251215 (887e7ef) View Download
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4. Crystallography and Experiment 4. Crystallography & Experiment

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5. Entities and Polymers Entities & Polymers (2)

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6. Fold Classification (SCOP + CATH) 1 domains

CATH v4.4 (1 domains)

Domain ID domain_id2h7eA00
Class class2 — Mainly Beta
Architecture architecture30 — Roll
Topology topology29 — PH-domain like
Homologous superfamily homologous superfamily30 — Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)
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7. Citations (1)