← Back to search
1mk9

CRYSTAL STRUCTURE OF AN INTEGRIN BETA3-TALIN CHIMERA

Method: X-RAY DIFFRACTION
▼

1. Protein Identity and Related Structures Protein Identity & Related Structures

Integrin Beta3

Homo sapiens

UniProt P05106

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein heterocomplex Heteromer Protein 2 TALIN × 1 （P54939） water × 1 Consistent with protein count
2 Protein heterocomplex Heteromer Protein 2 TALIN × 1 （P54939） water × 2 Consistent with protein count
3 Protein heterocomplex Heteromer Protein 2 TALIN × 1 （P54939） water × 1 Consistent with protein count
4 Protein heterocomplex Heteromer Protein 2 TALIN × 1 （P54939） water × 2 Consistent with protein count

Other States of the Same Protein in the Database

Monomer
1s4x 2kv9 2l91 2ljd 2lje 2ljf 2rmz 2rn0

8 assemblies

Homodimer

None

Homotetramer

None

Other homooligomers

None

Heteromeric or nucleic-acid complex
1kup 1kuz 1l5g 1m1x 1m8o 1miz 1mk7 1mk7 1mk9 1mk9 1mk9 1mk9

169 assemblies; showing the first 12

View Construct and Data Evidence
UniProt name ITB3_HUMAN
Isoform —
PDB entities 1
Chains and sequence ranges Author chain A； PDBConstruct 5–16； UniProt 765–776 Author chain C； PDBConstruct 5–16； UniProt 765–776 Author chain E； PDBConstruct 5–16； UniProt 765–776 Author chain G； PDBConstruct 5–16； UniProt 765–776

TALIN

Gallus gallus

UniProt P54939

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein heterocomplex Heteromer Protein 2 Integrin Beta3 × 1 （P05106） water × 1 Consistent with protein count
2 Protein heterocomplex Heteromer Protein 2 Integrin Beta3 × 1 （P05106） water × 2 Consistent with protein count
3 Protein heterocomplex Heteromer Protein 2 Integrin Beta3 × 1 （P05106） water × 1 Consistent with protein count
4 Protein heterocomplex Heteromer Protein 2 Integrin Beta3 × 1 （P05106） water × 2 Consistent with protein count

Other States of the Same Protein in the Database

Monomer
1mix 2hrj

2 assemblies

Homodimer

None

Homotetramer

None

Other homooligomers

None

Heteromeric or nucleic-acid complex
1miz 1mk7 1mk7 1mk9 1mk9 1mk9 1mk9 1rkc 1zvz 2h7d 2h7e 2k00

13 assemblies; showing the first 12

View Construct and Data Evidence
UniProt name TLN1_CHICK
Isoform —
PDB entities 2
Chains and sequence ranges Author chain B； PDBConstruct 1–192； UniProt 209–400 Author chain D； PDBConstruct 1–192； UniProt 209–400 Author chain F； PDBConstruct 1–192； UniProt 209–400 Author chain H； PDBConstruct 1–192； UniProt 209–400

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

▼

2. Structure Basics 2. Structure Basics

Entry ID entry_id1mk9
Deposition date deposition_date2002-08-28
Structure title titleCRYSTAL STRUCTURE OF AN INTEGRIN BETA3-TALIN CHIMERA
Keywords keywordsFOCAL ADHESION, INTEGRIN BINDING, FERM DOMAIN, CYTOSKELETON NPXY MOTIF, PTB DOMAIN, structural protein; STRUCTURAL PROTEIN
Experimental Method methodX-RAY DIFFRACTION
▼

3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

1mk9__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

1mk9__assembly_1__model_1 | I(q)

10-2 10-1 105 106 q (1/Angstrom) I(q)
100 plotted points; both axes use logarithmic scales.

1mk9__assembly_1__model_1 | P(r) · Pending

The new assembly/model P(r) has not been calculated yet This placeholder does not display legacy data r (Angstrom) P(r)
P(r) will be calculated and displayed separately for the same assembly/model.
Rg（Guinier）21.40 Å
Rg (electron density)20.66 Å
Total Rg21.43 Å
Atom count1665
Residues205
Excluded volume29933 ų
Maximum q0.500 Å⁻¹
Assembly Model Structure unit Oligomeric description Status CRYSOL Actions
1 1 1mk9__assembly_1__model_1 dimeric （2） Success 4.1.3-1-20251215 (887e7ef) View Download
2 1 1mk9__assembly_2__model_1 dimeric （2） Success 4.1.3-1-20251215 (887e7ef) View Download
3 1 1mk9__assembly_3__model_1 dimeric （2） Success 4.1.3-1-20251215 (887e7ef) View Download
4 1 1mk9__assembly_4__model_1 dimeric （2） Success 4.1.3-1-20251215 (887e7ef) View Download
▶

4. Crystallography and Experiment 4. Crystallography & Experiment

▶

5. Entities and Polymers Entities & Polymers (3)

▼

6. Fold Classification (SCOP + CATH) 16 domains

SCOP 2.08 (8 domains)

Domain ID domain_idd1mk9b1
Class classa — All alpha proteins
Fold Fold folda.11 — Acyl-CoA binding protein-like
Superfamily Superfamily superfamilya.11.2 — Second domain of FERM
Family Family familya.11.2.1 — Second domain of FERM
Domain ID domain_idd1mk9b2
Class classb — All beta proteins
Fold Fold foldb.55 — PH domain-like barrel
Superfamily Superfamily superfamilyb.55.1 — PH domain-like
Family Family familyb.55.1.5 — Third domain of FERM
Domain ID domain_idd1mk9d1
Class classa — All alpha proteins
Fold Fold folda.11 — Acyl-CoA binding protein-like
Superfamily Superfamily superfamilya.11.2 — Second domain of FERM
Family Family familya.11.2.1 — Second domain of FERM
Domain ID domain_idd1mk9d2
Class classb — All beta proteins
Fold Fold foldb.55 — PH domain-like barrel
Superfamily Superfamily superfamilyb.55.1 — PH domain-like
Family Family familyb.55.1.5 — Third domain of FERM
Domain ID domain_idd1mk9f1
Class classa — All alpha proteins
Fold Fold folda.11 — Acyl-CoA binding protein-like
Superfamily Superfamily superfamilya.11.2 — Second domain of FERM
Family Family familya.11.2.1 — Second domain of FERM
Domain ID domain_idd1mk9f2
Class classb — All beta proteins
Fold Fold foldb.55 — PH domain-like barrel
Superfamily Superfamily superfamilyb.55.1 — PH domain-like
Family Family familyb.55.1.5 — Third domain of FERM
Domain ID domain_idd1mk9h1
Class classa — All alpha proteins
Fold Fold folda.11 — Acyl-CoA binding protein-like
Superfamily Superfamily superfamilya.11.2 — Second domain of FERM
Family Family familya.11.2.1 — Second domain of FERM
Domain ID domain_idd1mk9h2
Class classb — All beta proteins
Fold Fold foldb.55 — PH domain-like barrel
Superfamily Superfamily superfamilyb.55.1 — PH domain-like
Family Family familyb.55.1.5 — Third domain of FERM

CATH v4.4 (8 domains)

Domain ID domain_id1mk9B01
Class class1 — Mainly Alpha
Architecture architecture20 — Up-down Bundle
Topology topology80 — Acyl-CoA Binding Protein
Homologous superfamily homologous superfamily10 —
Domain ID domain_id1mk9B02
Class class2 — Mainly Beta
Architecture architecture30 — Roll
Topology topology29 — PH-domain like
Homologous superfamily homologous superfamily30 — Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)
Domain ID domain_id1mk9D01
Class class1 — Mainly Alpha
Architecture architecture20 — Up-down Bundle
Topology topology80 — Acyl-CoA Binding Protein
Homologous superfamily homologous superfamily10 —
Domain ID domain_id1mk9D02
Class class2 — Mainly Beta
Architecture architecture30 — Roll
Topology topology29 — PH-domain like
Homologous superfamily homologous superfamily30 — Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)
Domain ID domain_id1mk9F01
Class class1 — Mainly Alpha
Architecture architecture20 — Up-down Bundle
Topology topology80 — Acyl-CoA Binding Protein
Homologous superfamily homologous superfamily10 —
Domain ID domain_id1mk9F02
Class class2 — Mainly Beta
Architecture architecture30 — Roll
Topology topology29 — PH-domain like
Homologous superfamily homologous superfamily30 — Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)
Domain ID domain_id1mk9H01
Class class1 — Mainly Alpha
Architecture architecture20 — Up-down Bundle
Topology topology80 — Acyl-CoA Binding Protein
Homologous superfamily homologous superfamily10 —
Domain ID domain_id1mk9H02
Class class2 — Mainly Beta
Architecture architecture30 — Roll
Topology topology29 — PH-domain like
Homologous superfamily homologous superfamily30 — Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)
▶

7. Citations (1)