2jex

Transcription activator structure reveals redox control of a replication initiation reaction

Method: X-RAY DIFFRACTION

1. Protein Identity and Related Structures Protein Identity & Related Structures

REGULATORY PROTEIN E2

BOVINE PAPILLOMAVIRUS TYPE 1

UniProt P03122

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein monomer Monomer Protein 1 water × 1 Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name VE2_BPV1
Isoform
PDB entities 1
Chains and sequence ranges Author chain A; PDBConstruct 1–209; UniProt 1–209

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

2. Structure Basics 2. Structure Basics

Entry ID entry_id2jex
Deposition date deposition_date2007-01-24
Structure title titleTranscription activator structure reveals redox control of a replication initiation reaction
Keywords keywords;NUCLEAR PROTEIN, DNA REPLICATION, PHOSPHORYLATION, TRANSCRIPTION REGULATION, VIRAL TRANSCRIPTION FACTOR, BOVINE PAPILLOMAVIRUS, REPLICATION INITIATION, EARLY PROTEIN, TRANSCRIPTION, REDOX CONTROL, E1, E2, OXIDATION, ACTIVATOR, REPRESSOR, DNA-BINDING ;; TRANSCRIPTION
Experimental Method methodX-RAY DIFFRACTION

3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

2jex__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

2jex__assembly_1__model_1 | I(q)

10-2 10-1 105 106 q (1/Angstrom) I(q)
100 plotted points; both axes use logarithmic scales.

2jex__assembly_1__model_1 | P(r) · Pending

The new assembly/model P(r) has not been calculated yet This placeholder does not display legacy data r (Angstrom) P(r)
P(r) will be calculated and displayed separately for the same assembly/model.
Rg(Guinier)21.47 Å
Rg (electron density)20.63 Å
Total Rg21.44 Å
Atom count1572
Residues197
Excluded volume27606 ų
Maximum q0.500 Å⁻¹
Assembly Model Structure unit Oligomeric description Status CRYSOL Actions
1 1 2jex__assembly_1__model_1 monomeric (1) Success 4.1.3-1-20251215 (887e7ef) View Download

4. Crystallography and Experiment 4. Crystallography & Experiment

5. Entities and Polymers Entities & Polymers (2)

6. Fold Classification (SCOP + CATH) 3 domains

SCOP 2.08 (1 domains)

Domain ID domain_idd2jexa_
Class classb — All beta proteins
Fold Fold foldb.91 — E2 regulatory, transactivation domain
Superfamily Superfamily superfamilyb.91.1 — E2 regulatory, transactivation domain
Family Family familyb.91.1.0 — automated matches

CATH v4.4 (2 domains)

Domain ID domain_id2jexA01
Class class1 — Mainly Alpha
Architecture architecture10 — Orthogonal Bundle
Topology topology287 — Helix Hairpins
Homologous superfamily homologous superfamily30 — E2 (early) protein, N terminal domain, subdomain 1
Domain ID domain_id2jexA02
Class class2 — Mainly Beta
Architecture architecture170 — Beta Complex
Topology topology200 — Regulatory Protein E2; Chain: A; Domain 2
Homologous superfamily homologous superfamily10 — Papillomavirus E2 early protein domain

7. Citations (1)