Homo sapiens
| Assembly | Physical composition | Protein state | Molecular copy count | Associated components | Data consistency |
|---|---|---|---|---|---|
| 1 | Protein heterocomplex | Heteromer | Protein 2 | RING-box protein 1 × 1 （P62877） ZINC ION × 3 water × 2 | Consistent with protein count |
| UniProt name | CUL5_HUMAN |
| Isoform | — |
| PDB entities | 1 |
| Chains and sequence ranges | Author chain C； PDBConstruct 3–382； UniProt 401–780 |
Homo sapiens
| Assembly | Physical composition | Protein state | Molecular copy count | Associated components | Data consistency |
|---|---|---|---|---|---|
| 1 | Protein heterocomplex | Heteromer | Protein 2 | Cullin-5 × 1 （Q93034） ZINC ION × 3 water × 2 | Consistent with protein count |
| UniProt name | RBX1_HUMAN |
| Isoform | — |
| PDB entities | 2 |
| Chains and sequence ranges | Author chain R； PDBConstruct 3–106； UniProt 5–108 |
The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.
| Entry ID entry_id | 3dpl |
| Deposition date deposition_date | 2008-07-08 |
| Structure title title | Structural Insights into NEDD8 Activation of Cullin-RING Ligases: Conformational Control of Conjugation. |
| Keywords keywords | ;ubiquitin, NEDD8, cullin, Host-virus interaction, Receptor, Ubl conjugation, Ubl conjugation pathway, Acetylation, Cytoplasm, DNA damage, DNA repair, Metal-binding, Nucleus, Zinc, Zinc-finger, LIGASE ;; LIGASE |
| Experimental Method method | X-RAY DIFFRACTION |
This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.
Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)
| Rg（Guinier） | 26.69 Å |
| Rg (electron density) | 26.08 Å |
| Total Rg | 26.87 Å |
| Atom count | 3859 |
| Residues | 465 |
| Excluded volume | 69237 ų |
| Maximum q | 0.500 Å⁻¹ |
| Domain ID domain_id | d3dplr_ |
| Class class | g — Small proteins |
| Fold Fold fold | g.44 — RING/U-box |
| Superfamily Superfamily superfamily | g.44.1 — RING/U-box |
| Family Family family | g.44.1.1 — RING finger domain, C3HC4 |
| Domain ID domain_id | 3dplC01 |
| Class class | 1 — Mainly Alpha |
| Architecture architecture | 20 — Up-down Bundle |
| Topology topology | 1310 — 5 helical Cullin repeat like |
| Homologous superfamily homologous superfamily | 10 — Cullin Repeats |
| Domain ID domain_id | 3dplC02 |
| Class class | 3 — Alpha Beta |
| Architecture architecture | 30 — 2-Layer Sandwich |
| Topology topology | 230 — Ribosomal Protein S5; domain 2 |
| Homologous superfamily homologous superfamily | 130 — Cullin; Chain C, Domain 2 |
| Domain ID domain_id | 3dplC03 |
| Class class | 1 — Mainly Alpha |
| Architecture architecture | 10 — Orthogonal Bundle |
| Topology topology | 10 — Arc Repressor Mutant, subunit A |
| Homologous superfamily homologous superfamily | 10 — Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain |
| Domain ID domain_id | 3dplR00 |
| Class class | 3 — Alpha Beta |
| Architecture architecture | 30 — 2-Layer Sandwich |
| Topology topology | 40 — Herpes Virus-1 |
| Homologous superfamily homologous superfamily | 10 — Zinc/RING finger domain, C3HC4 (zinc finger) |