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3jso

Classic Protein With a New Twist: crystal structure of a LexA repressor DNA complex

Method: X-RAY DIFFRACTION
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1. Protein Identity and Related Structures Protein Identity & Related Structures

LexA repressor

Escherichia coli K-12

UniProt P0A7C2

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–DNA Homooligomer Protein 2 DNA 2 ;DNA (5'-D(*TP*AP*TP*AP*CP*TP*GP*TP*AP*TP*AP*TP*AP*TP*AP*TP*AP*CP*AP*GP*TP*A)-3') ; × 2 water × 4 Consistent with all polymers

Other States of the Same Protein in the Database

Monomer
1lea 1leb

2 assemblies

Homodimer
1jhc 1jhe 1jhf 1jhh

4 assemblies

Homotetramer

None

Other homooligomers

None

Heteromeric or nucleic-acid complex
3jso 3jsp 3k3r 7b5g 7b5g 7b5g 7b5g 8trg

8 assemblies

View Construct and Data Evidence
UniProt name LEXA_ECOLI
Isoform —
PDB entities 1
Chains and sequence ranges Author chain A； PDBConstruct 1–202； UniProt 1–202 Author chain B； PDBConstruct 1–202； UniProt 1–202

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

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2. Structure Basics 2. Structure Basics

Entry ID entry_id3jso
Deposition date deposition_date2009-09-10
Structure title titleClassic Protein With a New Twist: crystal structure of a LexA repressor DNA complex
Keywords keywords;protein-DNA complex, winged helix-turn-helix, double helix, repressor, LexA, SOS system, Autocatalytic cleavage, DNA damage, DNA repair, DNA replication, DNA-binding, Hydrolase, SOS response, Transcription, Transcription regulation, Hydrolase-DNA COMPLEX ;; Hydrolase/DNA
Experimental Method methodX-RAY DIFFRACTION
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3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

3jso__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

3jso__assembly_1__model_1 | I(q)

10-2 10-1 106 107 q (1/Angstrom) I(q)
100 plotted points; both axes use logarithmic scales.

3jso__assembly_1__model_1 | P(r) · Pending

The new assembly/model P(r) has not been calculated yet This placeholder does not display legacy data r (Angstrom) P(r)
P(r) will be calculated and displayed separately for the same assembly/model.
Rg（Guinier）32.27 Å
Rg (electron density)31.17 Å
Total Rg31.86 Å
Atom count3798
Residues421
Excluded volume65083 ų
Maximum q0.500 Å⁻¹
Assembly Model Structure unit Oligomeric description Status CRYSOL Actions
1 1 3jso__assembly_1__model_1 tetrameric （4） Success 4.1.3-1-20251215 (887e7ef) View Download
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4. Crystallography and Experiment 4. Crystallography & Experiment

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5. Entities and Polymers Entities & Polymers (3)

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6. Fold Classification (SCOP + CATH) 8 domains

SCOP 2.08 (4 domains)

Domain ID domain_idd3jsoa1
Class classa — All alpha proteins
Fold Fold folda.4 — DNA/RNA-binding 3-helical bundle
Superfamily Superfamily superfamilya.4.5 — 'Winged helix' DNA-binding domain
Family Family familya.4.5.0 — automated matches
Domain ID domain_idd3jsoa2
Class classb — All beta proteins
Fold Fold foldb.87 — LexA/Signal peptidase
Superfamily Superfamily superfamilyb.87.1 — LexA/Signal peptidase
Family Family familyb.87.1.1 — LexA-related
Domain ID domain_idd3jsob1
Class classa — All alpha proteins
Fold Fold folda.4 — DNA/RNA-binding 3-helical bundle
Superfamily Superfamily superfamilya.4.5 — 'Winged helix' DNA-binding domain
Family Family familya.4.5.0 — automated matches
Domain ID domain_idd3jsob2
Class classb — All beta proteins
Fold Fold foldb.87 — LexA/Signal peptidase
Superfamily Superfamily superfamilyb.87.1 — LexA/Signal peptidase
Family Family familyb.87.1.1 — LexA-related

CATH v4.4 (4 domains)

Domain ID domain_id3jsoA01
Class class1 — Mainly Alpha
Architecture architecture10 — Orthogonal Bundle
Topology topology10 — Arc Repressor Mutant, subunit A
Homologous superfamily homologous superfamily10 — Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain
Domain ID domain_id3jsoA02
Class class2 — Mainly Beta
Architecture architecture10 — Ribbon
Topology topology109 — Umud Fragment, subunit A
Homologous superfamily homologous superfamily10 — Umud Fragment, subunit A
Domain ID domain_id3jsoB01
Class class1 — Mainly Alpha
Architecture architecture10 — Orthogonal Bundle
Topology topology10 — Arc Repressor Mutant, subunit A
Homologous superfamily homologous superfamily10 — Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain
Domain ID domain_id3jsoB02
Class class2 — Mainly Beta
Architecture architecture10 — Ribbon
Topology topology109 — Umud Fragment, subunit A
Homologous superfamily homologous superfamily10 — Umud Fragment, subunit A
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7. Citations (1)