4a3k

RNA Polymerase II initial transcribing complex with a 7nt DNA-RNA hybrid

Method: X-RAY DIFFRACTION

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1. Protein Identity and Related Structures Protein Identity & Related Structures

DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1

OrganismNot specified

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Other combination	Heteromer	Protein 12 DNA 2 RNA 1	DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB2 × 1 （P08518） DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB3 × 1 （P16370） DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB4 × 1 （P20433） DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC 1 × 1 （P20434） DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC 2 × 1 （P20435） RPB7, DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB7 × 1 （P34087） DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC 3 × 1 （P20436） DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB9 × 1 （P27999） DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC 5 × 1 （P22139） DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB11 × 1 （P38902） DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC 4 × 1 （P40422） 5'-D(TPAPAPGPTPAPCPTPTPGPAP)-3' × 1 5'-R(APCPCPAPGPGPAP)-3' × 1 ;5'-D(APGPCPTPCPAPAPGPTPAPCPTPTPDTP TPTPCPCPBRUGPGPTPCPAPTPT)-3' ; × 1 ZINC ION × 8 MAGNESIUM ION × 1	Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	RPB1_YEAST
Isoform	—
PDB entities	1
Chains and sequence ranges	Author chain A； PDBConstruct 1–1732； UniProt 1–1732

DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB2

OrganismNot specified

UniProt P08518

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Other combination	Heteromer	Protein 12 DNA 2 RNA 1	DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1 × 1 （P04050） DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB3 × 1 （P16370） DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB4 × 1 （P20433） DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC 1 × 1 （P20434） DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC 2 × 1 （P20435） RPB7, DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB7 × 1 （P34087） DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC 3 × 1 （P20436） DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB9 × 1 （P27999） DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC 5 × 1 （P22139） DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB11 × 1 （P38902） DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC 4 × 1 （P40422） 5'-D(TPAPAPGPTPAPCPTPTPGPAP)-3' × 1 5'-R(APCPCPAPGPGPAP)-3' × 1 ;5'-D(APGPCPTPCPAPAPGPTPAPCPTPTPDTP TPTPCPCPBRUGPGPTPCPAPTPT)-3' ; × 1 ZINC ION × 8 MAGNESIUM ION × 1	Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	RPB2_YEAST
Isoform	—
PDB entities	2
Chains and sequence ranges	Author chain B； PDBConstruct 1–1224； UniProt 1–1224

DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB3

OrganismNot specified

UniProt P16370

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Other combination	Heteromer	Protein 12 DNA 2 RNA 1	DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1 × 1 （P04050） DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB2 × 1 （P08518） DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB4 × 1 （P20433） DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC 1 × 1 （P20434） DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC 2 × 1 （P20435） RPB7, DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB7 × 1 （P34087） DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC 3 × 1 （P20436） DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB9 × 1 （P27999） DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC 5 × 1 （P22139） DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB11 × 1 （P38902） DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC 4 × 1 （P40422） 5'-D(TPAPAPGPTPAPCPTPTPGPAP)-3' × 1 5'-R(APCPCPAPGPGPAP)-3' × 1 ;5'-D(APGPCPTPCPAPAPGPTPAPCPTPTPDTP TPTPCPCPBRUGPGPTPCPAPTPT)-3' ; × 1 ZINC ION × 8 MAGNESIUM ION × 1	Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	RPB3_YEAST
Isoform	—
PDB entities	3
Chains and sequence ranges	Author chain C； PDBConstruct 1–318； UniProt 1–318

DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB4

OrganismNot specified

UniProt P20433

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Other combination	Heteromer	Protein 12 DNA 2 RNA 1	DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1 × 1 （P04050） DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB2 × 1 （P08518） DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB3 × 1 （P16370） DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC 1 × 1 （P20434） DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC 2 × 1 （P20435） RPB7, DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB7 × 1 （P34087） DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC 3 × 1 （P20436） DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB9 × 1 （P27999） DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC 5 × 1 （P22139） DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB11 × 1 （P38902） DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC 4 × 1 （P40422） 5'-D(TPAPAPGPTPAPCPTPTPGPAP)-3' × 1 5'-R(APCPCPAPGPGPAP)-3' × 1 ;5'-D(APGPCPTPCPAPAPGPTPAPCPTPTPDTP TPTPCPCPBRUGPGPTPCPAPTPT)-3' ; × 1 ZINC ION × 8 MAGNESIUM ION × 1	Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	RPB4_YEAST
Isoform	—
PDB entities	4
Chains and sequence ranges	Author chain D； PDBConstruct 1–221； UniProt 1–221

DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC 1

OrganismNot specified

UniProt P20434

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Other combination	Heteromer	Protein 12 DNA 2 RNA 1	DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1 × 1 （P04050） DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB2 × 1 （P08518） DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB3 × 1 （P16370） DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB4 × 1 （P20433） DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC 2 × 1 （P20435） RPB7, DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB7 × 1 （P34087） DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC 3 × 1 （P20436） DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB9 × 1 （P27999） DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC 5 × 1 （P22139） DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB11 × 1 （P38902） DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC 4 × 1 （P40422） 5'-D(TPAPAPGPTPAPCPTPTPGPAP)-3' × 1 5'-R(APCPCPAPGPGPAP)-3' × 1 ;5'-D(APGPCPTPCPAPAPGPTPAPCPTPTPDTP TPTPCPCPBRUGPGPTPCPAPTPT)-3' ; × 1 ZINC ION × 8 MAGNESIUM ION × 1	Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	RPAB1_YEAST
Isoform	—
PDB entities	5
Chains and sequence ranges	Author chain E； PDBConstruct 1–215； UniProt 1–215

DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC 2

OrganismNot specified

UniProt P20435

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Other combination	Heteromer	Protein 12 DNA 2 RNA 1	DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1 × 1 （P04050） DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB2 × 1 （P08518） DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB3 × 1 （P16370） DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB4 × 1 （P20433） DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC 1 × 1 （P20434） RPB7, DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB7 × 1 （P34087） DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC 3 × 1 （P20436） DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB9 × 1 （P27999） DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC 5 × 1 （P22139） DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB11 × 1 （P38902） DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC 4 × 1 （P40422） 5'-D(TPAPAPGPTPAPCPTPTPGPAP)-3' × 1 5'-R(APCPCPAPGPGPAP)-3' × 1 ;5'-D(APGPCPTPCPAPAPGPTPAPCPTPTPDTP TPTPCPCPBRUGPGPTPCPAPTPT)-3' ; × 1 ZINC ION × 8 MAGNESIUM ION × 1	Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	RPAB2_YEAST
Isoform	—
PDB entities	6
Chains and sequence ranges	Author chain F； PDBConstruct 1–155； UniProt 1–155

RPB7, DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB7

OrganismNot specified

UniProt P34087

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Other combination	Heteromer	Protein 12 DNA 2 RNA 1	DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1 × 1 （P04050） DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB2 × 1 （P08518） DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB3 × 1 （P16370） DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB4 × 1 （P20433） DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC 1 × 1 （P20434） DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC 2 × 1 （P20435） DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC 3 × 1 （P20436） DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB9 × 1 （P27999） DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC 5 × 1 （P22139） DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB11 × 1 （P38902） DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC 4 × 1 （P40422） 5'-D(TPAPAPGPTPAPCPTPTPGPAP)-3' × 1 5'-R(APCPCPAPGPGPAP)-3' × 1 ;5'-D(APGPCPTPCPAPAPGPTPAPCPTPTPDTP TPTPCPCPBRUGPGPTPCPAPTPT)-3' ; × 1 ZINC ION × 8 MAGNESIUM ION × 1	Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	RPB7_YEAST
Isoform	—
PDB entities	7
Chains and sequence ranges	Author chain G； PDBConstruct 1–171； UniProt 1–171

DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC 3

OrganismNot specified

UniProt P20436

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Other combination	Heteromer	Protein 12 DNA 2 RNA 1	DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1 × 1 （P04050） DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB2 × 1 （P08518） DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB3 × 1 （P16370） DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB4 × 1 （P20433） DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC 1 × 1 （P20434） DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC 2 × 1 （P20435） RPB7, DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB7 × 1 （P34087） DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB9 × 1 （P27999） DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC 5 × 1 （P22139） DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB11 × 1 （P38902） DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC 4 × 1 （P40422） 5'-D(TPAPAPGPTPAPCPTPTPGPAP)-3' × 1 5'-R(APCPCPAPGPGPAP)-3' × 1 ;5'-D(APGPCPTPCPAPAPGPTPAPCPTPTPDTP TPTPCPCPBRUGPGPTPCPAPTPT)-3' ; × 1 ZINC ION × 8 MAGNESIUM ION × 1	Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	RPAB3_YEAST
Isoform	—
PDB entities	8
Chains and sequence ranges	Author chain H； PDBConstruct 1–146； UniProt 1–146

DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB9

OrganismNot specified

UniProt P27999

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Other combination	Heteromer	Protein 12 DNA 2 RNA 1	DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1 × 1 （P04050） DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB2 × 1 （P08518） DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB3 × 1 （P16370） DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB4 × 1 （P20433） DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC 1 × 1 （P20434） DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC 2 × 1 （P20435） RPB7, DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB7 × 1 （P34087） DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC 3 × 1 （P20436） DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC 5 × 1 （P22139） DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB11 × 1 （P38902） DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC 4 × 1 （P40422） 5'-D(TPAPAPGPTPAPCPTPTPGPAP)-3' × 1 5'-R(APCPCPAPGPGPAP)-3' × 1 ;5'-D(APGPCPTPCPAPAPGPTPAPCPTPTPDTP TPTPCPCPBRUGPGPTPCPAPTPT)-3' ; × 1 ZINC ION × 8 MAGNESIUM ION × 1	Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	RPB9_YEAST
Isoform	—
PDB entities	9
Chains and sequence ranges	Author chain I； PDBConstruct 1–122； UniProt 1–122

DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC 5

OrganismNot specified

UniProt P22139

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Other combination	Heteromer	Protein 12 DNA 2 RNA 1	DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1 × 1 （P04050） DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB2 × 1 （P08518） DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB3 × 1 （P16370） DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB4 × 1 （P20433） DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC 1 × 1 （P20434） DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC 2 × 1 （P20435） RPB7, DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB7 × 1 （P34087） DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC 3 × 1 （P20436） DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB9 × 1 （P27999） DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB11 × 1 （P38902） DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC 4 × 1 （P40422） 5'-D(TPAPAPGPTPAPCPTPTPGPAP)-3' × 1 5'-R(APCPCPAPGPGPAP)-3' × 1 ;5'-D(APGPCPTPCPAPAPGPTPAPCPTPTPDTP TPTPCPCPBRUGPGPTPCPAPTPT)-3' ; × 1 ZINC ION × 8 MAGNESIUM ION × 1	Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	RPAB5_YEAST
Isoform	—
PDB entities	10
Chains and sequence ranges	Author chain J； PDBConstruct 1–70； UniProt 1–70

DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB11

OrganismNot specified

UniProt P38902

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Other combination	Heteromer	Protein 12 DNA 2 RNA 1	DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1 × 1 （P04050） DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB2 × 1 （P08518） DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB3 × 1 （P16370） DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB4 × 1 （P20433） DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC 1 × 1 （P20434） DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC 2 × 1 （P20435） RPB7, DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB7 × 1 （P34087） DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC 3 × 1 （P20436） DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB9 × 1 （P27999） DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC 5 × 1 （P22139） DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC 4 × 1 （P40422） 5'-D(TPAPAPGPTPAPCPTPTPGPAP)-3' × 1 5'-R(APCPCPAPGPGPAP)-3' × 1 ;5'-D(APGPCPTPCPAPAPGPTPAPCPTPTPDTP TPTPCPCPBRUGPGPTPCPAPTPT)-3' ; × 1 ZINC ION × 8 MAGNESIUM ION × 1	Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	RPB11_YEAST
Isoform	—
PDB entities	11
Chains and sequence ranges	Author chain K； PDBConstruct 1–120； UniProt 1–120

DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC 4

OrganismNot specified

UniProt P40422

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Other combination	Heteromer	Protein 12 DNA 2 RNA 1	DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1 × 1 （P04050） DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB2 × 1 （P08518） DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB3 × 1 （P16370） DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB4 × 1 （P20433） DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC 1 × 1 （P20434） DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC 2 × 1 （P20435） RPB7, DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB7 × 1 （P34087） DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC 3 × 1 （P20436） DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB9 × 1 （P27999） DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC 5 × 1 （P22139） DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB11 × 1 （P38902） 5'-D(TPAPAPGPTPAPCPTPTPGPAP)-3' × 1 5'-R(APCPCPAPGPGPAP)-3' × 1 ;5'-D(APGPCPTPCPAPAPGPTPAPCPTPTPDTP TPTPCPCPBRUGPGPTPCPAPTPT)-3' ; × 1 ZINC ION × 8 MAGNESIUM ION × 1	Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	RPAB4_YEAST
Isoform	—
PDB entities	12
Chains and sequence ranges	Author chain L； PDBConstruct 1–70； UniProt 1–70

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

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2. Structure Basics 2. Structure Basics

Entry ID entry_id	4a3k
Deposition date deposition_date	2011-09-30
Structure title title	RNA Polymerase II initial transcribing complex with a 7nt DNA-RNA hybrid
Keywords keywords	TRANSCRIPTION, TRANSCRIPTION INITIATION; TRANSCRIPTION
Experimental Method method	X-RAY DIFFRACTION

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3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

4a3k__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

4a3k__assembly_1__model_1 | I(q)

100 plotted points; both axes use logarithmic scales.

4a3k__assembly_1__model_1 | P(r) · Pending

P(r) will be calculated and displayed separately for the same assembly/model.

Rg（Guinier）	50.69 Å
Rg (electron density)	50.48 Å
Total Rg	50.65 Å
Atom count	31940
Residues	3963
Excluded volume	567460 Å³
Maximum q	0.500 Å⁻¹

Assembly	Model	Structure unit	Oligomeric description	Status	CRYSOL	Actions
1	1	`4a3k__assembly_1__model_1`	pentadecameric （15）	Success	4.1.3-1-20251215 (887e7ef)	View Download

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4. Crystallography and Experiment 4. Crystallography & Experiment

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5. Entities and Polymers Entities & Polymers (17)

Entity 1 Entity 1 polymer

Description description	DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1
Molecular weight formula_weight	191664.4 kDa
EC 编号 ec_number	2.7.7.6
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	A
Atom count atom_count	31940

MVGQQYSSAPLRTVKEVQFGLFSPEEVRAISVAKIRFPETMDETQTRAKIGGLNDPRLGSIDRNLKCQTCQEGMNECPGHFGHIDLAKPVFHVGFIAKIKKVCECVCMHCGKLLLDEHNELMRQALAIKDSKKRFAAIWTLCKTKMVCETDVPSEDDPTQLVSRGGCGNTQPTIRKDGLKLVGSWKKDRATGDADEPELRVLSTEEILNIFKHISVKDFTSLGFNEVFSRPEWMILTCLPVPPPPVRPSISFNESQRGEDDLTFKLADILKANISLETLEHNGAPHHAIEEAESLLQFHVATYMDNDIAGQPQALQKSGRPVKSIRARLKGKEGRIRGNLMGKRVDFSARTVISGDPNLELDQVGVPKSIAKTLTYPEVVTPYNIDRLTQLVRNGPNEHPGAKYVIRDSGDRIDLRYSKRAGDIQLQYGWKVERHIMDNDPVLFNRQPSLHKMSMMAHRVKVIPYSTFRLNLSVTSPYNADFDGDEMNLHVPQSEETRAELSQLCAVPLQIVSPQSNKPCMGIVQDTLCGIRKLTLRDTFIELDQVLNMLYWVPDWDGVIPTPAIIKPKPLWSGKQILSVAIPNGIHLQRFDEGTTLLSPKDNGMLIIDGQIIFGVVEKKTVGSSNGGLIHVVTREKGPQVCAKLFGNIQKVVNFWLLHNGFSTGIGDTIADGPTMREITETIAEAKKKVLDVTKEAQANLLTAKHGMTLRESFEDNVVRFLNEARDKAGRLAEVNLKDLNNVKQMVMAGSKGSFINIAQMSACVGQQSVEGKRIAFGFVDRTLPHFSKDDYSPESKGFVENSYLRGLTPQEFFFHAMGGREGLIDTAVKTAETGYIQRRLVKALEDIMVHYDNTTRNSLGNVIQFIYGEDGMDAAHIEKQSLDTIGGSDAAFEKRYRVDLLNTDHTLDPSLLESGSEILGDLKLQVLLDEEYKQLVKDRKFLREVFVDGEANWPLPVNIRRIIQNAQQTFHIDHTKPSDLTIKDIVLGVKDLQENLLVLRGKNEIIQNAQRDAVTLFCCLLRSRLATRRVLQEYRLTKQAFDWVLSNIEAQFLRSVVHPGEMVGVLAAQSIGEPATQMTLNTFHFAGVASKKVTSGVPRLKEILNVAKNMKTPSLTVYLEPGHAADQEQAKLIRSAIEHTTLKSVTIASEIYYDPDPRSTVIPEDEEIIQLHFSLLDEEAEQSFDQQSPWLLRLELDRAAMNDKDLTMGQVGERIKQTFKNDLFVIWSEDNDEKLIIRCRVVRPKSLDAETEAEEDHMLKKIENTMLENITLRGVENIERVVMMKYDRKVPSPTGEYVKEPEWVLETDGVNLSEVMTVPGIDPTRIYTNSFIDIMEVLGIEAGRAALYKEVYNVIASDGSYVNYRHMALLVDVMTTQGGLTSVTRHGFNRSNTGALMRCSFEETVEILFEAGASAELDDCRGVSENVILGQMAPIGTGAFDVMIDEESLVKYMPEQKITEIEDGQDGGVTPYSNESGLVNADLDVKDELMFSPLVDSGSNDAMAGGFTAYGGADYGEATSPFGAYGEAPTSPGFGVSSPGFSPTSPTYSPTSPAYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPAYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPNYSPTSPSYSPTSPGYSPGSPAYSPKQDEQKHNENENS

Entity 2 Entity 2 polymer

Description description	DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB2
Molecular weight formula_weight	138937.3 kDa
EC 编号 ec_number	2.7.7.6
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	B

MSDLANSEKYYDEDPYGFEDESAPITAEDSWAVISAFFREKGLVSQQLDSFNQFVDYTLQDIICEDSTLILEQLAQHTTESDNISRKYEISFGKIYVTKPMVNESDGVTHALYPQEARLRNLTYSSGLFVDVKKRTYEAIDVPGRELKYELIAEESEDDSESGKVFIGRLPIMLRSKNCYLSEATESDLYKLKECPFDMGGYFIINGSEKVLIAQERSAGNIVQVFKKAAPSPISHVAEIRSALEKGSRFISTLQVKLYGREGSSARTIKATLPYIKQDIPIVIIFRALGIIPDGEILEHICYDVNDWQMLEMLKPCVEDGFVIQDRETALDFIGRRGTALGIKKEKRIQYAKDILQKEFLPHITQLEGFESRKAFFLGYMINRLLLCALDRKDQDDRDHFGKKRLDLAGPLLAQLFKTLFKKLTKDIFRYMQRTVEEAHDFNMKLAINAKTITSGLKYALATGNWGEQKKAMSSRAGVSQVLNRYTYSSTLSHLRRTNTPIGRDGKLAKPRQLHNTHWGLVCPAETPEGQACGLVKNLSLMSCISVGTDPMPIITFLSEWGMEPLEDYVPHQSPDATRVFVNGVWHGVHRNPARLMETLRTLRRKGDINPEVSMIRDIREKELKIFTDAGRVYRPLFIVEDDESLGHKELKVRKGHIAKLMATEYQDIEGGFEDVEEYTWSSLLNEGLVEYIDAEEEESILIAMQPEDLEPAEANEENDLDVDPAKRIRVSHHATTFTHCEIHPSMILGVAASIIPFPDHNQSPRNTYQSAMGKQAMGVFLTNYNVRMDTMANILYYPQKPLGTTRAMEYLKFRELPAGQNAIVAIACYSGYNQEDSMIMNQSSIDRGLFRSLFFRSYMDQEKKYGMSITETFEKPQRTNTLRMKHGTYDKLDDDGLIAPGVRVSGEDVIIGKTTPISPDEEELGQRTAYHSKRDASTPLRSTENGIVDQVLVTTNQDGLKFVKVRVRTTKIPQIGDKFASRHGQKGTIGITYRREDMPFTAEGIVPDLIINPHAIPSRMTVAHLIECLLSKVAALSGNEGDASPFTDITVEGISKLLREHGYQSRGFEVMYNGHTGKKLMAQIFFGPTYYQRLRHMVDDKIHARARGPMQVLTRQPVEGRSRDGGLRFGEMERDCMIAHGAASFLKERLMEASDAFRVHICGICGLMTVIAKLNHNQFECKGCDNKIDIYQIHIPYAAKLLFQELMAMNITPRLYTDRSRDF

Entity 3 Entity 3 polymer

Description description	DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB3
Molecular weight formula_weight	35330.5 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	C

MSEEGPQVKIREASKDNVDFILSNVDLAMANSLRRVMIAEIPTLAIDSVEVETNTTVLADEFIAHRLGLIPLQSMDIEQLEYSRDCFCEDHCDKCSVVLTLQAFGESESTTNVYSKDLVIVSNLMGRNIGHPIIQDKEGNGVLICKLRKGQELKLTCVAKKGIAKEHAKWGPAAAIEFEYDPWNKLKHTDYWYEQDSAKEWPQSKNCEYEDPPNEGDPFDYKAQADTFYMNVESVGSIPVDQVVVRGIDTLQKKVASILLALTQMDQDKVNFASGDNNTASNMLGSNEDVMMTGAEQDPYSNASQMGNTGSGGYDNAW

Entity 4 Entity 4 polymer

Description description	DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB4
Molecular weight formula_weight	25451.2 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	D

MNVSTSTFQTRRRRLKKVEEEENAATLQLGQEFQLKQINHQGEEEELIALNLSEARLVIKEALVERRRAFKRSQKKHKKKHLKHENANDETTAVEDEDDDLDEDDVNADDDDFMHSETREKELESIDVLLEQTTGGNNKDLKNTMQYLTNFSRFRDQETVGAVIQLLKSTGLHPFEVAQLGSLACDTADEAKTLIPSLNNKISDDELERILKELSNLETLY

Entity 5 Entity 5 polymer

Description description	DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC 1
Molecular weight formula_weight	25117.1 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	E

MDQENERNISRLWRAFRTVKEMVKDRGYFITQEEVELPLEDFKAKYCDSMGRPQRKMMSFQANPTEESISKFPDMGSLWVEFCDEPSVGVKTMKTFVIHIQEKNFQTGIFVYQNNITPSAMKLVPSIPPATIETFNEAALVVNITHHELVPKHIRLSSDEKRELLKRYRLKESQLPRIQRADPVALYLGLKRGEVVKIIRKSETSGRYASYRICM

Entity 6 Entity 6 polymer

Description description	DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC 2
Molecular weight formula_weight	17931.8 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	F

MSDYEEAFNDGNENFEDFDVEHFSDEETYEEKPQFKDGETTDANGKTIVTGGNGPEDFQQHEQIRRKTLKEKAIPKDQRATTPYMTKYERARILGTRALQISMNAPVFVDLEGETDPLRIAMKELAEKKIPLVIRRYLPDGSFEDWSVEELIVDL

Entity 7 Entity 7 polymer

Description description	RPB7, DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB7
Molecular weight formula_weight	19081.1 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	G

MFFIKDLSLNITLHPSFFGPRMKQYLKTKLLEEVEGSCTGKFGYILCVLDYDNIDIQRGRILPTDGSAEFNVKYRAVVFKPFKGEVVDGTVVSCSQHGFEVQVGPMKVFVTKHLMPQDLTFNAGSNPPSYQSSEDVITIKSRIRVKIEGCISQVSSIHAIGSIKEDYLGAI

Entity 8 Entity 8 polymer

Description description	DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC 3
Molecular weight formula_weight	16525.4 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	H

MSNTLFDDIFQVSEVDPGRYNKVCRIEAASTTQDQCKLTLDINVELFPVAAQDSLTVTIASSLNLEDTPANDSSATRSWRPPQAGDRSLADDYDYVMYGTAYKFEEVSKDLIAVYYSFGGLLMRLEGNYRNLNNLKQENAYLLIRR

Entity 9 Entity 9 polymer

Description description	DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB9
Molecular weight formula_weight	14308.2 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	I

MTTFRFCRDCNNMLYPREDKENNRLLFECRTCSYVEEAGSPLVYRHELITNIGETAGVVQDIGSDPTLPRSDRECPKCHSRENVFFQSQQRRKDTSMVLFFVCLSCSHIFTSDQKNKRTQFS

Entity 10 Entity 10 polymer

Description description	DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC 5
Molecular weight formula_weight	8290.7 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	J

MIVPVRCFSCGKVVGDKWESYLNLLQEDELDEGTALSRLGLKRYCCRRMILTHVDLIEKFLRYNPLEKRD

Entity 11 Entity 11 polymer

Description description	DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB11
Molecular weight formula_weight	13633.5 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	K

MNAPDRFELFLLGEGESKLKIDPDTKAPNAVVITFEKEDHTLGNLIRAELLNDRKVLFAAYKVEHPFFARFKLRIQTTEGYDPKDALKNACNSIINKLGALKTNFETEWNLQTLAADDAF

Entity 12 Entity 12 polymer

Description description	DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC 4
Molecular weight formula_weight	7730.0 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	L

MSREGFQIPTNLDAAAAGTSQARTATLKYICAECSSKLSLSRTDAVRCKDCGHRILLKARTKRLVQFEAR

Entity 13 Entity 13 polymer

Description description	5'-D(TPAPAPGPTPAPCPTPTPGP*AP)-3'
Molecular weight formula_weight	3372.2 kDa
Source method src_method	syn
Copy count entity_count	1

Polymer Polymer

Polymer type type	polydeoxyribonucleotide
Chain IDs strand_id	N

TAAGTACTTGA

Entity 14 Entity 14 polymer

Description description	5'-R(APCPCPAPGPGP*AP)-3'
Molecular weight formula_weight	2243.4 kDa
Source method src_method	syn
Copy count entity_count	1

Polymer Polymer

Polymer type type	polyribonucleotide
Chain IDs strand_id	P

ACCAGGA

Entity 15 Entity 15 polymer

Description description	;5'-D(APGPCPTPCPAPAPGPTPAPCPTPTPDTP TPTPCPCPBRUGPGPTPCPAPTPT)-3' ;
Molecular weight formula_weight	7984.0 kDa
Source method src_method	syn
Copy count entity_count	1

Polymer Polymer

Polymer type type	polydeoxyribonucleotide
Chain IDs strand_id	T

AGCTCAAGTACTTTTTCCUGGTCATT

Entity 16 Entity 16 non-polymer

Description description	ZINC ION
Molecular weight formula_weight	65.4 kDa
Source method src_method	syn
Copy count entity_count	8

Entity 17 Entity 17 non-polymer

Description description	MAGNESIUM ION
Molecular weight formula_weight	24.3 kDa
Source method src_method	syn
Copy count entity_count	1

▼

6. Fold Classification (SCOP + CATH) 21 domains

CATH v4.4 (21 domains)

Domain ID domain_id	4a3kA01
Class class	1 — Mainly Alpha
Architecture architecture	10 — Orthogonal Bundle
Topology topology	274 — Enzyme I; Chain A, domain 2
Homologous superfamily homologous superfamily	100 — RNA polymerase Rpb1, domain 3

Domain ID domain_id	4a3kA02
Class class	3 — Alpha Beta
Architecture architecture	30 — 2-Layer Sandwich
Topology topology	1360 — Gyrase A; domain 2
Homologous superfamily homologous superfamily	140 —

Domain ID domain_id	4a3kB04
Class class	3 — Alpha Beta
Architecture architecture	90 — Alpha-Beta Complex
Topology topology	1110 — Dna-directed Rna Polymerase Ii 140kd Polypeptide; Chain: B; domain 3
Homologous superfamily homologous superfamily	10 — RNA polymerase Rpb2, domain 2

Domain ID domain_id	4a3kB05
Class class	3 — Alpha Beta
Architecture architecture	90 — Alpha-Beta Complex
Topology topology	1070 — Hypothetical Protein Ta0175; Chain: A, domain 2
Homologous superfamily homologous superfamily	20 —

Domain ID domain_id	4a3kB06
Class class	2 — Mainly Beta
Architecture architecture	40 — Beta Barrel
Topology topology	270 — Dna-directed Rna Polymerase Ii 140kd Polypeptide; Chain: B; Domain 6
Homologous superfamily homologous superfamily	10 — DNA-directed RNA polymerase, subunit 2, domain 6

Domain ID domain_id	4a3kB07
Class class	2 — Mainly Beta
Architecture architecture	40 — Beta Barrel
Topology topology	50 — OB fold (Dihydrolipoamide Acetyltransferase, E2P)
Homologous superfamily homologous superfamily	150 — RNA polymerase II, Rpb2 subunit, wall domain

Domain ID domain_id	4a3kB08
Class class	3 — Alpha Beta
Architecture architecture	90 — Alpha-Beta Complex
Topology topology	1800 — DCoH-like
Homologous superfamily homologous superfamily	10 — RNA polymerase alpha subunit dimerisation domain

Domain ID domain_id	4a3kC01
Class class	3 — Alpha Beta
Architecture architecture	30 — 2-Layer Sandwich
Topology topology	1360 — Gyrase A; domain 2
Homologous superfamily homologous superfamily	10 — RNA polymerase, RBP11-like subunit

Domain ID domain_id	4a3kC02
Class class	2 — Mainly Beta
Architecture architecture	170 — Beta Complex
Topology topology	120 — RNA Polymerase Alpha Subunit; Chain A, domain 2
Homologous superfamily homologous superfamily	12 — DNA-directed RNA polymerase, insert domain

Domain ID domain_id	4a3kD02
Class class	1 — Mainly Alpha
Architecture architecture	20 — Up-down Bundle
Topology topology	1250 — Growth Hormone; Chain: A;
Homologous superfamily homologous superfamily	40 — RNA Polymerase II, Rpb4 subunit

Domain ID domain_id	4a3kE01
Class class	3 — Alpha Beta
Architecture architecture	40 — 3-Layer(aba) Sandwich
Topology topology	1340 — Dna-directed Rna Polymerases I, Ii, And Iii 27 Kd Polypeptide; Chain: A; domain 1
Homologous superfamily homologous superfamily	10 — RNA polymerase, Rpb5, N-terminal domain

Domain ID domain_id	4a3kE02
Class class	3 — Alpha Beta
Architecture architecture	90 — Alpha-Beta Complex
Topology topology	940 — Eukaryotic RPB6 RNA polymerase subunit
Homologous superfamily homologous superfamily	20 — RPB5-like RNA polymerase subunit

Domain ID domain_id	4a3kF00
Class class	3 — Alpha Beta
Architecture architecture	90 — Alpha-Beta Complex
Topology topology	940 — Eukaryotic RPB6 RNA polymerase subunit
Homologous superfamily homologous superfamily	10 — RNA polymerase subunit, RPB6/omega

Domain ID domain_id	4a3kG01
Class class	3 — Alpha Beta
Architecture architecture	30 — 2-Layer Sandwich
Topology topology	1490 — Dna Ligase; domain 1
Homologous superfamily homologous superfamily	120 — RNA polymerase Rpb7-like, N-terminal domain

Domain ID domain_id	4a3kG02
Class class	2 — Mainly Beta
Architecture architecture	40 — Beta Barrel
Topology topology	50 — OB fold (Dihydrolipoamide Acetyltransferase, E2P)
Homologous superfamily homologous superfamily	140 — Nucleic acid-binding proteins

Domain ID domain_id	4a3kH00
Class class	2 — Mainly Beta
Architecture architecture	40 — Beta Barrel
Topology topology	50 — OB fold (Dihydrolipoamide Acetyltransferase, E2P)
Homologous superfamily homologous superfamily	140 — Nucleic acid-binding proteins

Domain ID domain_id	4a3kI01
Class class	2 — Mainly Beta
Architecture architecture	20 — Single Sheet
Topology topology	25 — N-terminal domain of TfIIb
Homologous superfamily homologous superfamily	10 —

Domain ID domain_id	4a3kI02
Class class	2 — Mainly Beta
Architecture architecture	20 — Single Sheet
Topology topology	25 — N-terminal domain of TfIIb
Homologous superfamily homologous superfamily	10 —

Domain ID domain_id	4a3kJ00
Class class	1 — Mainly Alpha
Architecture architecture	10 — Orthogonal Bundle
Topology topology	10 — Arc Repressor Mutant, subunit A
Homologous superfamily homologous superfamily	60 — Homeodomain-like

Domain ID domain_id	4a3kK00
Class class	3 — Alpha Beta
Architecture architecture	30 — 2-Layer Sandwich
Topology topology	1360 — Gyrase A; domain 2
Homologous superfamily homologous superfamily	10 — RNA polymerase, RBP11-like subunit

Domain ID domain_id	4a3kL00
Class class	2 — Mainly Beta
Architecture architecture	20 — Single Sheet
Topology topology	28 — Rubrerythrin, domain 2
Homologous superfamily homologous superfamily	30 — RNA polymerase ii, chain L

▶

Unit-cell length a length_a	221.910 Å
Unit-cell length b length_b	391.360 Å
Unit-cell length c length_c	283.920 Å
Unit-cell angle α angle_alpha	90.00 °
Unit-cell angle β angle_beta	90.00 °
Unit-cell angle γ angle_gamma	90.00 °
Molecules per unit cell Z z_pdb	8

Space group space_group	C 2 2 21
Space-group number int_tables_number	20
Crystal system crystal_system	—

Resolution resolution	3.500 Å
Low-resolution limit resolution_low	48.950 Å
R factor r_factor	0.1588
R_work r_work	0.1583
R_free r_free	0.1849

RNA Polymerase II initial transcribing complex with a 7nt DNA-RNA hybrid

1. Protein Identity and Related Structures Protein Identity & Related Structures

DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1

State in the Current Structure

Other States of the Same Protein in the Database

Monomer

Homodimer

Homotetramer

Other homooligomers

Heteromeric or nucleic-acid complex

DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB2

State in the Current Structure

Other States of the Same Protein in the Database

Monomer

Homodimer

Homotetramer

Other homooligomers

Heteromeric or nucleic-acid complex

DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB3

State in the Current Structure

Other States of the Same Protein in the Database

Monomer

Homodimer

Homotetramer

Other homooligomers

Heteromeric or nucleic-acid complex

DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB4

State in the Current Structure

Other States of the Same Protein in the Database

Monomer

Homodimer

Homotetramer

Other homooligomers

Heteromeric or nucleic-acid complex

DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC 1

State in the Current Structure

Other States of the Same Protein in the Database

Monomer

Homodimer

Homotetramer

Other homooligomers

Heteromeric or nucleic-acid complex

DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC 2

State in the Current Structure

Other States of the Same Protein in the Database

Monomer

Homodimer

Homotetramer

Other homooligomers

Heteromeric or nucleic-acid complex

RPB7, DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB7

State in the Current Structure

Other States of the Same Protein in the Database

Monomer

Homodimer

Homotetramer

Other homooligomers

Heteromeric or nucleic-acid complex

DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC 3

State in the Current Structure

Other States of the Same Protein in the Database

Monomer

Homodimer

Homotetramer

Other homooligomers

Heteromeric or nucleic-acid complex

DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB9

State in the Current Structure

Other States of the Same Protein in the Database

Monomer

Homodimer

Homotetramer

Other homooligomers

Heteromeric or nucleic-acid complex

DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC 5

State in the Current Structure

Other States of the Same Protein in the Database

Monomer

Homodimer

Homotetramer