4ei2

Crystal Structures of MthK RCK gating ring bound to Barium

Method: X-RAY DIFFRACTION

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1. Protein Identity and Related Structures Protein Identity & Related Structures

Calcium-gated potassium channel mthK

Methanothermobacter thermautotrophicus

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein monomer	Monomer	Protein 1	BARIUM ION × 5 water × 1	Consistent with protein count
10	Protein monomer	Monomer	Protein 1	BARIUM ION × 2 water × 1	Consistent with protein count
11	Protein monomer	Monomer	Protein 1	BARIUM ION × 4	Consistent with protein count
12	Protein monomer	Monomer	Protein 1	BARIUM ION × 2	Consistent with protein count
13	Protein monomer	Monomer	Protein 1	BARIUM ION × 4 water × 1	Consistent with protein count
14	Protein monomer	Monomer	Protein 1	BARIUM ION × 3	Consistent with protein count
15	Protein monomer	Monomer	Protein 1	BARIUM ION × 3 water × 1	Consistent with protein count
16	Protein monomer	Monomer	Protein 1	BARIUM ION × 3 water × 1	Consistent with protein count
2	Protein monomer	Monomer	Protein 1	BARIUM ION × 4 water × 1	Consistent with protein count
3	Protein monomer	Monomer	Protein 1	BARIUM ION × 3 water × 1	Consistent with protein count
4	Protein monomer	Monomer	Protein 1	BARIUM ION × 5 water × 1	Consistent with protein count
5	Protein monomer	Monomer	Protein 1	BARIUM ION × 6 water × 1	Consistent with protein count
6	Protein monomer	Monomer	Protein 1	BARIUM ION × 4 water × 1	Consistent with protein count
7	Protein monomer	Monomer	Protein 1	BARIUM ION × 4 water × 1	Consistent with protein count
8	Protein monomer	Monomer	Protein 1	BARIUM ION × 2 water × 1	Consistent with protein count
9	Protein monomer	Monomer	Protein 1	BARIUM ION × 3	Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	MTHK_METTH
Isoform	—
PDB entities	1
Chains and sequence ranges	Author chain A； PDBConstruct 1–230； UniProt 107–336 Author chain B； PDBConstruct 1–230； UniProt 107–336 Author chain C； PDBConstruct 1–230； UniProt 107–336 Author chain D； PDBConstruct 1–230； UniProt 107–336 Author chain E； PDBConstruct 1–230； UniProt 107–336 Author chain F； PDBConstruct 1–230； UniProt 107–336 Author chain G； PDBConstruct 1–230； UniProt 107–336 Author chain H； PDBConstruct 1–230； UniProt 107–336 Author chain I； PDBConstruct 1–230； UniProt 107–336 Author chain J； PDBConstruct 1–230； UniProt 107–336 Author chain K； PDBConstruct 1–230； UniProt 107–336 Author chain L； PDBConstruct 1–230； UniProt 107–336 Author chain M； PDBConstruct 1–230； UniProt 107–336 Author chain N； PDBConstruct 1–230； UniProt 107–336 Author chain O； PDBConstruct 1–230； UniProt 107–336 Author chain P； PDBConstruct 1–230； UniProt 107–336

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

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2. Structure Basics 2. Structure Basics

Entry ID entry_id	4ei2
Deposition date deposition_date	2012-04-04
Structure title title	Crystal Structures of MthK RCK gating ring bound to Barium
Keywords keywords	K+ CHANNEL, MEMBRANE PROTEIN, RCK DOMAIN, Ba2+ BINDING, ROSSMANN-FOLD, TRANSPORT PROTEIN; TRANSPORT PROTEIN
Experimental Method method	X-RAY DIFFRACTION

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3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

4ei2__assembly_11__model_1

Assembly 11 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

4ei2__assembly_11__model_1 | I(q)

100 plotted points; both axes use logarithmic scales.

4ei2__assembly_11__model_1 | P(r) · Pending

P(r) will be calculated and displayed separately for the same assembly/model.

Rg（Guinier）	21.64 Å
Rg (electron density)	20.57 Å
Total Rg	21.52 Å
Atom count	1743
Residues	224
Excluded volume	31199 Å³
Maximum q	0.500 Å⁻¹

Assembly	Model	Structure unit	Oligomeric description	Status	CRYSOL	Actions
1	1	`4ei2__assembly_1__model_1`	monomeric （1）	Success	4.1.3-1-20251215 (887e7ef)	View Download
2	1	`4ei2__assembly_2__model_1`	monomeric （1）	Success	4.1.3-1-20251215 (887e7ef)	View Download
3	1	`4ei2__assembly_3__model_1`	monomeric （1）	Success	4.1.3-1-20251215 (887e7ef)	View Download
4	1	`4ei2__assembly_4__model_1`	monomeric （1）	Success	4.1.3-1-20251215 (887e7ef)	View Download
5	1	`4ei2__assembly_5__model_1`	monomeric （1）	Success	4.1.3-1-20251215 (887e7ef)	View Download
6	1	`4ei2__assembly_6__model_1`	monomeric （1）	Success	4.1.3-1-20251215 (887e7ef)	View Download
7	1	`4ei2__assembly_7__model_1`	monomeric （1）	Success	4.1.3-1-20251215 (887e7ef)	View Download
8	1	`4ei2__assembly_8__model_1`	monomeric （1）	Success	4.1.3-1-20251215 (887e7ef)	View Download
9	1	`4ei2__assembly_9__model_1`	monomeric （1）	Success	4.1.3-1-20251215 (887e7ef)	View Download
10	1	`4ei2__assembly_10__model_1`	monomeric （1）	Success	4.1.3-1-20251215 (887e7ef)	View Download
11	1	`4ei2__assembly_11__model_1`	monomeric （1）	Success	4.1.3-1-20251215 (887e7ef)	View Download
12	1	`4ei2__assembly_12__model_1`	monomeric （1）	Success	4.1.3-1-20251215 (887e7ef)	View Download
13	1	`4ei2__assembly_13__model_1`	monomeric （1）	Success	4.1.3-1-20251215 (887e7ef)	View Download
14	1	`4ei2__assembly_14__model_1`	monomeric （1）	Success	4.1.3-1-20251215 (887e7ef)	View Download
15	1	`4ei2__assembly_15__model_1`	monomeric （1）	Success	4.1.3-1-20251215 (887e7ef)	View Download
16	1	`4ei2__assembly_16__model_1`	monomeric （1）	Success	4.1.3-1-20251215 (887e7ef)	View Download

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4. Crystallography and Experiment 4. Crystallography & Experiment

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5. Entities and Polymers Entities & Polymers (3)

Entity 1 Entity 1 polymer

Description description	Calcium-gated potassium channel mthK
Molecular weight formula_weight	26887.6 kDa
Source method src_method	man
Copy count entity_count	16

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	A,B,C,D,E,F,G,H,I,J,K,L,M,N,O,P
Atom count atom_count	27805

MGLIDVAKSRHVVICGWSESTLECLRELRGSEVFVLAEDENVRKKVLRSGANFVHGDPTRVSDLEKANVRGARAVIVDLESDSETIHCILGIRKIDESVRIIAEAERYENIEQLRMAGADQVISPFVISGRLMSRSIDDGYEAMFVQDVLAEESTRRMVEVPIPEGSKLEGVSVLDADIHDVTGVIIIGVGRGDELIIDPPRDYSFRAGDIILGIGKPEEIERLKNYISALVPRGSHHHHHH

Source Source

Source organism organism	Methanothermobacter thermautotrophicus
NCBI taxonomy ID ncbi_taxonomy_id	187420
Host organism host_organism	Escherichia coli

Entity 2 Entity 2 non-polymer

Description description	BARIUM ION
Molecular weight formula_weight	137.3 kDa
Source method src_method	syn
Copy count entity_count	57

Entity 3 Entity 3 water

Description description	water
Molecular weight formula_weight	18.0 kDa
Source method src_method	nat
Copy count entity_count	32

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6. Fold Classification (SCOP + CATH) 91 domains

SCOP 2.08 (43 domains)

Domain ID domain_id	d4ei2a1
Class class	c — Alpha and beta proteins (a/b)
Fold Fold fold	c.2 — NAD(P)-binding Rossmann-fold domains
Superfamily Superfamily superfamily	c.2.1 — NAD(P)-binding Rossmann-fold domains
Family Family family	c.2.1.9 — Potassium channel NAD-binding domain

Domain ID domain_id	d4ei2a2
Class class	d — Alpha and beta proteins (a+b)
Fold Fold fold	d.286 — TrkA C-terminal domain-like
Superfamily Superfamily superfamily	d.286.1 — TrkA C-terminal domain-like
Family Family family	d.286.1.0 — automated matches

Domain ID domain_id	d4ei2a3
Class class	l — Artifacts
Fold Fold fold	l.1 — Tags
Superfamily Superfamily superfamily	l.1.1 — Tags
Family Family family	l.1.1.1 — Tags

Domain ID domain_id	d4ei2b1
Class class	c — Alpha and beta proteins (a/b)
Fold Fold fold	c.2 — NAD(P)-binding Rossmann-fold domains
Superfamily Superfamily superfamily	c.2.1 — NAD(P)-binding Rossmann-fold domains
Family Family family	c.2.1.9 — Potassium channel NAD-binding domain

Domain ID domain_id	d4ei2b2
Class class	d — Alpha and beta proteins (a+b)
Fold Fold fold	d.286 — TrkA C-terminal domain-like
Superfamily Superfamily superfamily	d.286.1 — TrkA C-terminal domain-like
Family Family family	d.286.1.0 — automated matches

Domain ID domain_id	d4ei2c1
Class class	c — Alpha and beta proteins (a/b)
Fold Fold fold	c.2 — NAD(P)-binding Rossmann-fold domains
Superfamily Superfamily superfamily	c.2.1 — NAD(P)-binding Rossmann-fold domains
Family Family family	c.2.1.9 — Potassium channel NAD-binding domain

Domain ID domain_id	d4ei2c2
Class class	d — Alpha and beta proteins (a+b)
Fold Fold fold	d.286 — TrkA C-terminal domain-like
Superfamily Superfamily superfamily	d.286.1 — TrkA C-terminal domain-like
Family Family family	d.286.1.0 — automated matches

Domain ID domain_id	d4ei2c3
Class class	l — Artifacts
Fold Fold fold	l.1 — Tags
Superfamily Superfamily superfamily	l.1.1 — Tags
Family Family family	l.1.1.1 — Tags

Domain ID domain_id	d4ei2d1
Class class	c — Alpha and beta proteins (a/b)
Fold Fold fold	c.2 — NAD(P)-binding Rossmann-fold domains
Superfamily Superfamily superfamily	c.2.1 — NAD(P)-binding Rossmann-fold domains
Family Family family	c.2.1.9 — Potassium channel NAD-binding domain

Domain ID domain_id	d4ei2d2
Class class	d — Alpha and beta proteins (a+b)
Fold Fold fold	d.286 — TrkA C-terminal domain-like
Superfamily Superfamily superfamily	d.286.1 — TrkA C-terminal domain-like
Family Family family	d.286.1.0 — automated matches

Domain ID domain_id	d4ei2d3
Class class	l — Artifacts
Fold Fold fold	l.1 — Tags
Superfamily Superfamily superfamily	l.1.1 — Tags
Family Family family	l.1.1.1 — Tags

Domain ID domain_id	d4ei2e1
Class class	c — Alpha and beta proteins (a/b)
Fold Fold fold	c.2 — NAD(P)-binding Rossmann-fold domains
Superfamily Superfamily superfamily	c.2.1 — NAD(P)-binding Rossmann-fold domains
Family Family family	c.2.1.9 — Potassium channel NAD-binding domain

Domain ID domain_id	d4ei2e2
Class class	d — Alpha and beta proteins (a+b)
Fold Fold fold	d.286 — TrkA C-terminal domain-like
Superfamily Superfamily superfamily	d.286.1 — TrkA C-terminal domain-like
Family Family family	d.286.1.0 — automated matches

Domain ID domain_id	d4ei2e3
Class class	l — Artifacts
Fold Fold fold	l.1 — Tags
Superfamily Superfamily superfamily	l.1.1 — Tags
Family Family family	l.1.1.1 — Tags

Domain ID domain_id	d4ei2f1
Class class	c — Alpha and beta proteins (a/b)
Fold Fold fold	c.2 — NAD(P)-binding Rossmann-fold domains
Superfamily Superfamily superfamily	c.2.1 — NAD(P)-binding Rossmann-fold domains
Family Family family	c.2.1.9 — Potassium channel NAD-binding domain

Domain ID domain_id	d4ei2f2
Class class	d — Alpha and beta proteins (a+b)
Fold Fold fold	d.286 — TrkA C-terminal domain-like
Superfamily Superfamily superfamily	d.286.1 — TrkA C-terminal domain-like
Family Family family	d.286.1.0 — automated matches

Domain ID domain_id	d4ei2f3
Class class	l — Artifacts
Fold Fold fold	l.1 — Tags
Superfamily Superfamily superfamily	l.1.1 — Tags
Family Family family	l.1.1.1 — Tags

Domain ID domain_id	d4ei2g1
Class class	c — Alpha and beta proteins (a/b)
Fold Fold fold	c.2 — NAD(P)-binding Rossmann-fold domains
Superfamily Superfamily superfamily	c.2.1 — NAD(P)-binding Rossmann-fold domains
Family Family family	c.2.1.9 — Potassium channel NAD-binding domain

Domain ID domain_id	d4ei2g2
Class class	d — Alpha and beta proteins (a+b)
Fold Fold fold	d.286 — TrkA C-terminal domain-like
Superfamily Superfamily superfamily	d.286.1 — TrkA C-terminal domain-like
Family Family family	d.286.1.0 — automated matches

Domain ID domain_id	d4ei2g3
Class class	l — Artifacts
Fold Fold fold	l.1 — Tags
Superfamily Superfamily superfamily	l.1.1 — Tags
Family Family family	l.1.1.1 — Tags

Domain ID domain_id	d4ei2h1
Class class	c — Alpha and beta proteins (a/b)
Fold Fold fold	c.2 — NAD(P)-binding Rossmann-fold domains
Superfamily Superfamily superfamily	c.2.1 — NAD(P)-binding Rossmann-fold domains
Family Family family	c.2.1.9 — Potassium channel NAD-binding domain

Domain ID domain_id	d4ei2h2
Class class	d — Alpha and beta proteins (a+b)
Fold Fold fold	d.286 — TrkA C-terminal domain-like
Superfamily Superfamily superfamily	d.286.1 — TrkA C-terminal domain-like
Family Family family	d.286.1.0 — automated matches

Domain ID domain_id	d4ei2h3
Class class	l — Artifacts
Fold Fold fold	l.1 — Tags
Superfamily Superfamily superfamily	l.1.1 — Tags
Family Family family	l.1.1.1 — Tags

Domain ID domain_id	d4ei2i1
Class class	c — Alpha and beta proteins (a/b)
Fold Fold fold	c.2 — NAD(P)-binding Rossmann-fold domains
Superfamily Superfamily superfamily	c.2.1 — NAD(P)-binding Rossmann-fold domains
Family Family family	c.2.1.9 — Potassium channel NAD-binding domain

Domain ID domain_id	d4ei2i2
Class class	d — Alpha and beta proteins (a+b)
Fold Fold fold	d.286 — TrkA C-terminal domain-like
Superfamily Superfamily superfamily	d.286.1 — TrkA C-terminal domain-like
Family Family family	d.286.1.0 — automated matches

Domain ID domain_id	d4ei2j1
Class class	c — Alpha and beta proteins (a/b)
Fold Fold fold	c.2 — NAD(P)-binding Rossmann-fold domains
Superfamily Superfamily superfamily	c.2.1 — NAD(P)-binding Rossmann-fold domains
Family Family family	c.2.1.9 — Potassium channel NAD-binding domain

Domain ID domain_id	d4ei2j2
Class class	d — Alpha and beta proteins (a+b)
Fold Fold fold	d.286 — TrkA C-terminal domain-like
Superfamily Superfamily superfamily	d.286.1 — TrkA C-terminal domain-like
Family Family family	d.286.1.0 — automated matches

Domain ID domain_id	d4ei2j3
Class class	l — Artifacts
Fold Fold fold	l.1 — Tags
Superfamily Superfamily superfamily	l.1.1 — Tags
Family Family family	l.1.1.1 — Tags

Domain ID domain_id	d4ei2k1
Class class	c — Alpha and beta proteins (a/b)
Fold Fold fold	c.2 — NAD(P)-binding Rossmann-fold domains
Superfamily Superfamily superfamily	c.2.1 — NAD(P)-binding Rossmann-fold domains
Family Family family	c.2.1.9 — Potassium channel NAD-binding domain

Domain ID domain_id	d4ei2k2
Class class	d — Alpha and beta proteins (a+b)
Fold Fold fold	d.286 — TrkA C-terminal domain-like
Superfamily Superfamily superfamily	d.286.1 — TrkA C-terminal domain-like
Family Family family	d.286.1.0 — automated matches

Domain ID domain_id	d4ei2k3
Class class	l — Artifacts
Fold Fold fold	l.1 — Tags
Superfamily Superfamily superfamily	l.1.1 — Tags
Family Family family	l.1.1.1 — Tags

Domain ID domain_id	d4ei2l1
Class class	c — Alpha and beta proteins (a/b)
Fold Fold fold	c.2 — NAD(P)-binding Rossmann-fold domains
Superfamily Superfamily superfamily	c.2.1 — NAD(P)-binding Rossmann-fold domains
Family Family family	c.2.1.9 — Potassium channel NAD-binding domain

Domain ID domain_id	d4ei2l2
Class class	d — Alpha and beta proteins (a+b)
Fold Fold fold	d.286 — TrkA C-terminal domain-like
Superfamily Superfamily superfamily	d.286.1 — TrkA C-terminal domain-like
Family Family family	d.286.1.0 — automated matches

Domain ID domain_id	d4ei2m1
Class class	c — Alpha and beta proteins (a/b)
Fold Fold fold	c.2 — NAD(P)-binding Rossmann-fold domains
Superfamily Superfamily superfamily	c.2.1 — NAD(P)-binding Rossmann-fold domains
Family Family family	c.2.1.9 — Potassium channel NAD-binding domain

Domain ID domain_id	d4ei2m2
Class class	d — Alpha and beta proteins (a+b)
Fold Fold fold	d.286 — TrkA C-terminal domain-like
Superfamily Superfamily superfamily	d.286.1 — TrkA C-terminal domain-like
Family Family family	d.286.1.0 — automated matches

Domain ID domain_id	d4ei2m3
Class class	l — Artifacts
Fold Fold fold	l.1 — Tags
Superfamily Superfamily superfamily	l.1.1 — Tags
Family Family family	l.1.1.1 — Tags

Domain ID domain_id	d4ei2n1
Class class	c — Alpha and beta proteins (a/b)
Fold Fold fold	c.2 — NAD(P)-binding Rossmann-fold domains
Superfamily Superfamily superfamily	c.2.1 — NAD(P)-binding Rossmann-fold domains
Family Family family	c.2.1.9 — Potassium channel NAD-binding domain

Domain ID domain_id	d4ei2n2
Class class	d — Alpha and beta proteins (a+b)
Fold Fold fold	d.286 — TrkA C-terminal domain-like
Superfamily Superfamily superfamily	d.286.1 — TrkA C-terminal domain-like
Family Family family	d.286.1.0 — automated matches

Domain ID domain_id	d4ei2n3
Class class	l — Artifacts
Fold Fold fold	l.1 — Tags
Superfamily Superfamily superfamily	l.1.1 — Tags
Family Family family	l.1.1.1 — Tags

Domain ID domain_id	d4ei2o1
Class class	c — Alpha and beta proteins (a/b)
Fold Fold fold	c.2 — NAD(P)-binding Rossmann-fold domains
Superfamily Superfamily superfamily	c.2.1 — NAD(P)-binding Rossmann-fold domains
Family Family family	c.2.1.9 — Potassium channel NAD-binding domain

Domain ID domain_id	d4ei2o2
Class class	d — Alpha and beta proteins (a+b)
Fold Fold fold	d.286 — TrkA C-terminal domain-like
Superfamily Superfamily superfamily	d.286.1 — TrkA C-terminal domain-like
Family Family family	d.286.1.0 — automated matches

Domain ID domain_id	d4ei2p1
Class class	c — Alpha and beta proteins (a/b)
Fold Fold fold	c.2 — NAD(P)-binding Rossmann-fold domains
Superfamily Superfamily superfamily	c.2.1 — NAD(P)-binding Rossmann-fold domains
Family Family family	c.2.1.9 — Potassium channel NAD-binding domain

Domain ID domain_id	d4ei2p2
Class class	d — Alpha and beta proteins (a+b)
Fold Fold fold	d.286 — TrkA C-terminal domain-like
Superfamily Superfamily superfamily	d.286.1 — TrkA C-terminal domain-like
Family Family family	d.286.1.0 — automated matches

CATH v4.4 (48 domains)

Domain ID domain_id	4ei2A01
Class class	3 — Alpha Beta
Architecture architecture	40 — 3-Layer(aba) Sandwich
Topology topology	50 — Rossmann fold
Homologous superfamily homologous superfamily	720 — NAD(P)-binding Rossmann-like Domain

Domain ID domain_id	4ei2A02
Class class	1 — Mainly Alpha
Architecture architecture	20 — Up-down Bundle
Topology topology	5 — Single alpha-helices involved in coiled-coils or other helix-helix interfaces
Homologous superfamily homologous superfamily	870 — Voltage-gated potassium channel

Domain ID domain_id	4ei2A03
Class class	3 — Alpha Beta
Architecture architecture	30 — 2-Layer Sandwich
Topology topology	70 — Alpha-Beta Plaits
Homologous superfamily homologous superfamily	1450 — Regulator of K+ conductance, C-terminal domain

Domain ID domain_id	4ei2B01
Class class	3 — Alpha Beta
Architecture architecture	40 — 3-Layer(aba) Sandwich
Topology topology	50 — Rossmann fold
Homologous superfamily homologous superfamily	720 — NAD(P)-binding Rossmann-like Domain

Domain ID domain_id	4ei2B02
Class class	1 — Mainly Alpha
Architecture architecture	20 — Up-down Bundle
Topology topology	5 — Single alpha-helices involved in coiled-coils or other helix-helix interfaces
Homologous superfamily homologous superfamily	870 — Voltage-gated potassium channel

Domain ID domain_id	4ei2B03
Class class	3 — Alpha Beta
Architecture architecture	30 — 2-Layer Sandwich
Topology topology	70 — Alpha-Beta Plaits
Homologous superfamily homologous superfamily	1450 — Regulator of K+ conductance, C-terminal domain

Domain ID domain_id	4ei2C01
Class class	3 — Alpha Beta
Architecture architecture	40 — 3-Layer(aba) Sandwich
Topology topology	50 — Rossmann fold
Homologous superfamily homologous superfamily	720 — NAD(P)-binding Rossmann-like Domain

Domain ID domain_id	4ei2C02
Class class	1 — Mainly Alpha
Architecture architecture	20 — Up-down Bundle
Topology topology	5 — Single alpha-helices involved in coiled-coils or other helix-helix interfaces
Homologous superfamily homologous superfamily	870 — Voltage-gated potassium channel

Domain ID domain_id	4ei2C03
Class class	3 — Alpha Beta
Architecture architecture	30 — 2-Layer Sandwich
Topology topology	70 — Alpha-Beta Plaits
Homologous superfamily homologous superfamily	1450 — Regulator of K+ conductance, C-terminal domain

Domain ID domain_id	4ei2D01
Class class	3 — Alpha Beta
Architecture architecture	40 — 3-Layer(aba) Sandwich
Topology topology	50 — Rossmann fold
Homologous superfamily homologous superfamily	720 — NAD(P)-binding Rossmann-like Domain

Domain ID domain_id	4ei2D02
Class class	1 — Mainly Alpha
Architecture architecture	20 — Up-down Bundle
Topology topology	5 — Single alpha-helices involved in coiled-coils or other helix-helix interfaces
Homologous superfamily homologous superfamily	870 — Voltage-gated potassium channel

Domain ID domain_id	4ei2D03
Class class	3 — Alpha Beta
Architecture architecture	30 — 2-Layer Sandwich
Topology topology	70 — Alpha-Beta Plaits
Homologous superfamily homologous superfamily	1450 — Regulator of K+ conductance, C-terminal domain

Domain ID domain_id	4ei2E01
Class class	3 — Alpha Beta
Architecture architecture	40 — 3-Layer(aba) Sandwich
Topology topology	50 — Rossmann fold
Homologous superfamily homologous superfamily	720 — NAD(P)-binding Rossmann-like Domain

Domain ID domain_id	4ei2E02
Class class	1 — Mainly Alpha
Architecture architecture	20 — Up-down Bundle
Topology topology	5 — Single alpha-helices involved in coiled-coils or other helix-helix interfaces
Homologous superfamily homologous superfamily	870 — Voltage-gated potassium channel

Domain ID domain_id	4ei2E03
Class class	3 — Alpha Beta
Architecture architecture	30 — 2-Layer Sandwich
Topology topology	70 — Alpha-Beta Plaits
Homologous superfamily homologous superfamily	1450 — Regulator of K+ conductance, C-terminal domain

Domain ID domain_id	4ei2F01
Class class	3 — Alpha Beta
Architecture architecture	40 — 3-Layer(aba) Sandwich
Topology topology	50 — Rossmann fold
Homologous superfamily homologous superfamily	720 — NAD(P)-binding Rossmann-like Domain

Domain ID domain_id	4ei2F02
Class class	1 — Mainly Alpha
Architecture architecture	20 — Up-down Bundle
Topology topology	5 — Single alpha-helices involved in coiled-coils or other helix-helix interfaces
Homologous superfamily homologous superfamily	870 — Voltage-gated potassium channel

Domain ID domain_id	4ei2F03
Class class	3 — Alpha Beta
Architecture architecture	30 — 2-Layer Sandwich
Topology topology	70 — Alpha-Beta Plaits
Homologous superfamily homologous superfamily	1450 — Regulator of K+ conductance, C-terminal domain

Domain ID domain_id	4ei2G01
Class class	3 — Alpha Beta
Architecture architecture	40 — 3-Layer(aba) Sandwich
Topology topology	50 — Rossmann fold
Homologous superfamily homologous superfamily	720 — NAD(P)-binding Rossmann-like Domain

Domain ID domain_id	4ei2G02
Class class	1 — Mainly Alpha
Architecture architecture	20 — Up-down Bundle
Topology topology	5 — Single alpha-helices involved in coiled-coils or other helix-helix interfaces
Homologous superfamily homologous superfamily	870 — Voltage-gated potassium channel

Domain ID domain_id	4ei2G03
Class class	3 — Alpha Beta
Architecture architecture	30 — 2-Layer Sandwich
Topology topology	70 — Alpha-Beta Plaits
Homologous superfamily homologous superfamily	1450 — Regulator of K+ conductance, C-terminal domain

Domain ID domain_id	4ei2H01
Class class	3 — Alpha Beta
Architecture architecture	40 — 3-Layer(aba) Sandwich
Topology topology	50 — Rossmann fold
Homologous superfamily homologous superfamily	720 — NAD(P)-binding Rossmann-like Domain

Domain ID domain_id	4ei2H02
Class class	1 — Mainly Alpha
Architecture architecture	20 — Up-down Bundle
Topology topology	5 — Single alpha-helices involved in coiled-coils or other helix-helix interfaces
Homologous superfamily homologous superfamily	870 — Voltage-gated potassium channel

Domain ID domain_id	4ei2H03
Class class	3 — Alpha Beta
Architecture architecture	30 — 2-Layer Sandwich
Topology topology	70 — Alpha-Beta Plaits
Homologous superfamily homologous superfamily	1450 — Regulator of K+ conductance, C-terminal domain

Domain ID domain_id	4ei2I01
Class class	3 — Alpha Beta
Architecture architecture	40 — 3-Layer(aba) Sandwich
Topology topology	50 — Rossmann fold
Homologous superfamily homologous superfamily	720 — NAD(P)-binding Rossmann-like Domain

Domain ID domain_id	4ei2I02
Class class	1 — Mainly Alpha
Architecture architecture	20 — Up-down Bundle
Topology topology	5 — Single alpha-helices involved in coiled-coils or other helix-helix interfaces
Homologous superfamily homologous superfamily	870 — Voltage-gated potassium channel

Domain ID domain_id	4ei2I03
Class class	3 — Alpha Beta
Architecture architecture	30 — 2-Layer Sandwich
Topology topology	70 — Alpha-Beta Plaits
Homologous superfamily homologous superfamily	1450 — Regulator of K+ conductance, C-terminal domain

Domain ID domain_id	4ei2J01
Class class	3 — Alpha Beta
Architecture architecture	40 — 3-Layer(aba) Sandwich
Topology topology	50 — Rossmann fold
Homologous superfamily homologous superfamily	720 — NAD(P)-binding Rossmann-like Domain

Domain ID domain_id	4ei2J02
Class class	1 — Mainly Alpha
Architecture architecture	20 — Up-down Bundle
Topology topology	5 — Single alpha-helices involved in coiled-coils or other helix-helix interfaces
Homologous superfamily homologous superfamily	870 — Voltage-gated potassium channel

Domain ID domain_id	4ei2J03
Class class	3 — Alpha Beta
Architecture architecture	30 — 2-Layer Sandwich
Topology topology	70 — Alpha-Beta Plaits
Homologous superfamily homologous superfamily	1450 — Regulator of K+ conductance, C-terminal domain

Domain ID domain_id	4ei2K01
Class class	3 — Alpha Beta
Architecture architecture	40 — 3-Layer(aba) Sandwich
Topology topology	50 — Rossmann fold
Homologous superfamily homologous superfamily	720 — NAD(P)-binding Rossmann-like Domain

Domain ID domain_id	4ei2K02
Class class	1 — Mainly Alpha
Architecture architecture	20 — Up-down Bundle
Topology topology	5 — Single alpha-helices involved in coiled-coils or other helix-helix interfaces
Homologous superfamily homologous superfamily	870 — Voltage-gated potassium channel

Domain ID domain_id	4ei2K03
Class class	3 — Alpha Beta
Architecture architecture	30 — 2-Layer Sandwich
Topology topology	70 — Alpha-Beta Plaits
Homologous superfamily homologous superfamily	1450 — Regulator of K+ conductance, C-terminal domain

Domain ID domain_id	4ei2L01
Class class	3 — Alpha Beta
Architecture architecture	40 — 3-Layer(aba) Sandwich
Topology topology	50 — Rossmann fold
Homologous superfamily homologous superfamily	720 — NAD(P)-binding Rossmann-like Domain

Domain ID domain_id	4ei2L02
Class class	1 — Mainly Alpha
Architecture architecture	20 — Up-down Bundle
Topology topology	5 — Single alpha-helices involved in coiled-coils or other helix-helix interfaces
Homologous superfamily homologous superfamily	870 — Voltage-gated potassium channel

Domain ID domain_id	4ei2L03
Class class	3 — Alpha Beta
Architecture architecture	30 — 2-Layer Sandwich
Topology topology	70 — Alpha-Beta Plaits
Homologous superfamily homologous superfamily	1450 — Regulator of K+ conductance, C-terminal domain

Domain ID domain_id	4ei2M01
Class class	3 — Alpha Beta
Architecture architecture	40 — 3-Layer(aba) Sandwich
Topology topology	50 — Rossmann fold
Homologous superfamily homologous superfamily	720 — NAD(P)-binding Rossmann-like Domain

Domain ID domain_id	4ei2M02
Class class	1 — Mainly Alpha
Architecture architecture	20 — Up-down Bundle
Topology topology	5 — Single alpha-helices involved in coiled-coils or other helix-helix interfaces
Homologous superfamily homologous superfamily	870 — Voltage-gated potassium channel

Domain ID domain_id	4ei2M03
Class class	3 — Alpha Beta
Architecture architecture	30 — 2-Layer Sandwich
Topology topology	70 — Alpha-Beta Plaits
Homologous superfamily homologous superfamily	1450 — Regulator of K+ conductance, C-terminal domain

Domain ID domain_id	4ei2N01
Class class	3 — Alpha Beta
Architecture architecture	40 — 3-Layer(aba) Sandwich
Topology topology	50 — Rossmann fold
Homologous superfamily homologous superfamily	720 — NAD(P)-binding Rossmann-like Domain

Domain ID domain_id	4ei2N02
Class class	1 — Mainly Alpha
Architecture architecture	20 — Up-down Bundle
Topology topology	5 — Single alpha-helices involved in coiled-coils or other helix-helix interfaces
Homologous superfamily homologous superfamily	870 — Voltage-gated potassium channel

Domain ID domain_id	4ei2N03
Class class	3 — Alpha Beta
Architecture architecture	30 — 2-Layer Sandwich
Topology topology	70 — Alpha-Beta Plaits
Homologous superfamily homologous superfamily	1450 — Regulator of K+ conductance, C-terminal domain

Domain ID domain_id	4ei2O01
Class class	3 — Alpha Beta
Architecture architecture	40 — 3-Layer(aba) Sandwich
Topology topology	50 — Rossmann fold
Homologous superfamily homologous superfamily	720 — NAD(P)-binding Rossmann-like Domain

Domain ID domain_id	4ei2O02
Class class	1 — Mainly Alpha
Architecture architecture	20 — Up-down Bundle
Topology topology	5 — Single alpha-helices involved in coiled-coils or other helix-helix interfaces
Homologous superfamily homologous superfamily	870 — Voltage-gated potassium channel

Domain ID domain_id	4ei2O03
Class class	3 — Alpha Beta
Architecture architecture	30 — 2-Layer Sandwich
Topology topology	70 — Alpha-Beta Plaits
Homologous superfamily homologous superfamily	1450 — Regulator of K+ conductance, C-terminal domain

Domain ID domain_id	4ei2P01
Class class	3 — Alpha Beta
Architecture architecture	40 — 3-Layer(aba) Sandwich
Topology topology	50 — Rossmann fold
Homologous superfamily homologous superfamily	720 — NAD(P)-binding Rossmann-like Domain

Domain ID domain_id	4ei2P02
Class class	1 — Mainly Alpha
Architecture architecture	20 — Up-down Bundle
Topology topology	5 — Single alpha-helices involved in coiled-coils or other helix-helix interfaces
Homologous superfamily homologous superfamily	870 — Voltage-gated potassium channel

Domain ID domain_id	4ei2P03
Class class	3 — Alpha Beta
Architecture architecture	30 — 2-Layer Sandwich
Topology topology	70 — Alpha-Beta Plaits
Homologous superfamily homologous superfamily	1450 — Regulator of K+ conductance, C-terminal domain

▶

Unit-cell length a length_a	110.045 Å
Unit-cell length b length_b	136.419 Å
Unit-cell length c length_c	498.427 Å
Unit-cell angle α angle_alpha	90.00 °
Unit-cell angle β angle_beta	90.00 °
Unit-cell angle γ angle_gamma	90.00 °
Molecules per unit cell Z z_pdb	64

Space group space_group	P 21 21 21
Space-group number int_tables_number	19
Crystal system crystal_system	—

Resolution resolution	3.108 Å
Low-resolution limit resolution_low	30.000 Å
R factor r_factor	0.2094
R_work r_work	0.2089
R_free r_free	0.2425

Crystal Structures of MthK RCK gating ring bound to Barium

1. Protein Identity and Related Structures Protein Identity & Related Structures

Calcium-gated potassium channel mthK

State in the Current Structure

Other States of the Same Protein in the Database

2. Structure Basics 2. Structure Basics

3. Official assembly/model SAXS Official SAXS Profiles

4ei2__assembly_11__model_1

4ei2__assembly_11__model_1 | I(q)

4ei2__assembly_11__model_1 | P(r) · Pending

4. Crystallography and Experiment 4. Crystallography & Experiment

Unit cell Unit Cell

Symmetry Symmetry

Refinement Refinement

Diffraction experiment Diffraction

5. Entities and Polymers Entities & Polymers (3)

Entity 1 Entity 1 polymer

Polymer Polymer

Source Source

Entity 2 Entity 2 non-polymer

Entity 3 Entity 3 water

6. Fold Classification (SCOP + CATH) 91 domains

SCOP 2.08 (43 domains)

CATH v4.4 (48 domains)

7. Citations (1)

Crystal Structures of MthK RCK gating ring bound to Barium

1. Protein Identity and Related Structures Protein Identity & Related Structures

Calcium-gated potassium channel mthK

State in the Current Structure

Other States of the Same Protein in the Database

Monomer

Homodimer

Homotetramer

Other homooligomers

Heteromeric or nucleic-acid complex

2. Structure Basics 2. Structure Basics

3. Official assembly/model SAXS Official SAXS Profiles

4ei2__assembly_11__model_1

4ei2__assembly_11__model_1 | I(q)

4ei2__assembly_11__model_1 | P(r) · Pending

4. Crystallography and Experiment 4. Crystallography & Experiment

Unit cell Unit Cell

Symmetry Symmetry

Refinement Refinement

Diffraction experiment Diffraction

5. Entities and Polymers Entities & Polymers (3)

Entity 1 Entity 1 polymer

Polymer Polymer

Source Source

Entity 2 Entity 2 non-polymer

Entity 3 Entity 3 water

6. Fold Classification (SCOP + CATH) 91 domains

SCOP 2.08 (43 domains)

CATH v4.4 (48 domains)

7. Citations (1)