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4gp4

Structure of Recombinant Cytochrome ba3 Oxidase mutant Y133F from Thermus thermophilus

Method: X-RAY DIFFRACTION Dmax: 89.5 Å Quality: GOOD
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1. 蛋白身份与相关结构 Protein Identity & Related Structures

Cytochrome c oxidase subunit 1

Thermus thermophilus

UniProt Q5SJ79

当前结构中的状态

Assembly 聚集状态 构建体 突变与修饰 配体、离子与共同组分 实验方法与环境 结构质量
1 蛋白异源复合物 异源复合物 蛋白 × 3 PDB 声明：trimeric（3） 与蛋白拷贝数一致 链 A； UniProt 2–562 突变：Y133F Cytochrome c oxidase subunit 2 × 1 （Q5SJ80） Cytochrome c oxidase polypeptide 2A × 1 （P82543） CU COPPER (II) ION × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 PER PEROXIDE ION × 1 OLC (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate × 16 CUA DINUCLEAR COPPER ION × 1 X-RAY DIFFRACTION X-ray结晶条件：LIPIDIC CUBIC PHASE；pH 6.5；293 K；50mM Sodium Cacodylate, 1.6M NaCl, 40% PEG400, pH 6.5, Lipidic Cubic Phase, temperature 293K 分辨率 2.80 Å R-free 0.227

数据库中的同蛋白其他状态

以下每一行都是同一 UniProt 蛋白在另一个 PDB 条目中的 biological assembly， “相对当前条目”直接指出证据层面的不同；没有差异标签表示当前已读取字段一致。

其他 PDB 相对当前条目 4GP4 Assembly / 聚集状态 构建体 突变与修饰 配体、离子与非聚合物 实验方法与环境 结构质量
1EHK CRYSTAL STRUCTURE OF THE ABERRANT BA3-CYTOCHROME-C OXIDASE FROM THERMUS THERMOPHILUS 提交 2000-02-21 构建体不同 突变/修饰不同 配体/离子不同 实验环境不同 结构质量不同 Assembly 1 蛋白异源复合物 异源复合物；蛋白 × 3 PDB 声明：trimeric
链 A 1–562（562 aa） 片段：SUBUNIT I
未记录 BNG nonyl beta-D-glucopyranoside × 3 CU COPPER (II) ION × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 CUA DINUCLEAR COPPER ION × 1 X-RAY DIFFRACTION
X-ray结晶条件 VAPOR DIFFUSION, SITTING DROP；pH 7；293 K；PEG 2000, Bis-Tris buffer, nonyl-beta-D-glucoside, pH 7.0, VAPOR DIFFUSION, SITTING DROP, temperature 293K
分辨率 2.40 Å R-free 0.264
2QPD An unexpected outcome of surface-engineering an integral membrane protein: Improved crystallization of cytochrome ba3 oxidase from Thermus thermophilus 提交 2007-07-23 突变/修饰不同 配体/离子不同 实验环境不同 结构质量不同 Assembly 1 蛋白异源复合物 异源复合物；蛋白 × 3 PDB 声明：trimeric
链 A 2–562（561 aa）
突变：K258R CU1 COPPER (I) ION × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 CUA DINUCLEAR COPPER ION × 1 X-RAY DIFFRACTION
X-ray结晶条件 VAPOR DIFFUSION, SITTING DROP；pH 7；291 K；7% PEK 2K, 50 mM KCl, 20 mM Bis-Tris pH 7.0, 6.5 mM n-nonyl-beta-D-glucopyranoside, VAPOR DIFFUSION, SITTING DROP, temperature 291K
分辨率 3.25 Å R-free 0.307
2QPE An unexpected outcome of surface-engineering an integral membrane protein: Improved crystallization of cytochrome ba3 oxidase from Thermus thermophilus 提交 2007-07-23 突变/修饰不同 配体/离子不同 实验环境不同 结构质量不同 Assembly 1 蛋白异源复合物 异源复合物；蛋白 × 3 PDB 声明：trimeric
链 A 2–562（561 aa）
突变：K258R CU1 COPPER (I) ION × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 CUA DINUCLEAR COPPER ION × 1 X-RAY DIFFRACTION
X-ray结晶条件 VAPOR DIFFUSION, SITTING DROP；pH 7；291 K；7% PEK 2K, 50 mM KCl, 20 mM Bis-Tris, pH 7.0, 6.5 mM n-nonyl-beta-D-glucopyranoside, VAPOR DIFFUSION, SITTING DROP, temperature 291K
分辨率 2.90 Å R-free 0.302
3BVD Structure of Surface-engineered Cytochrome ba3 Oxidase from Thermus thermophilus under Xenon Pressure, 100psi 5min 提交 2008-01-07 突变/修饰不同 配体/离子不同 实验环境不同 结构质量不同 Assembly 1 蛋白异源复合物 异源复合物；蛋白 × 3 PDB 声明：trimeric
链 A 2–562（561 aa）
突变：K258R CU COPPER (II) ION × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 XE XENON × 7 CUA DINUCLEAR COPPER ION × 1 X-RAY DIFFRACTION
X-ray结晶条件 VAPOR DIFFUSION；pH 7；297 K；6-9% PEG 2000, 50mM KCl, 7.5-30mM bis-Tris pH 7.0, 6.5mM nonyl-B-D-glucopyranoside , VAPOR DIFFUSION, temperature 297K
分辨率 3.37 Å R-free 0.336
3EH3 Structure of the reduced form of cytochrome ba3 oxidase from Thermus thermophilus 提交 2008-09-11 构建体不同 突变/修饰不同 配体/离子不同 实验环境不同 结构质量不同 Assembly 1 蛋白异源复合物 异源复合物；蛋白 × 3 PDB 声明：trimeric
链 A 2–562（561 aa） 片段：UNP residues 6-562
突变：K258R CU1 COPPER (I) ION × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 CUA DINUCLEAR COPPER ION × 1 X-RAY DIFFRACTION
X-ray结晶条件 VAPOR DIFFUSION, SITTING DROP；pH 7；297 K；Peg 2000, Bis-tris, pH 7.0, VAPOR DIFFUSION, SITTING DROP, temperature 297K
分辨率 3.10 Å R-free 0.300
3EH3 Structure of the reduced form of cytochrome ba3 oxidase from Thermus thermophilus 提交 2008-09-11 构建体不同 突变/修饰不同 聚集状态不同 配体/离子不同 实验环境不同 结构质量不同 Assembly 2 蛋白单体 单体；蛋白 × 1 PDB 声明：monomeric
链 A 2–562（561 aa） 片段：UNP residues 6-562
突变：K258R CU1 COPPER (I) ION × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 X-RAY DIFFRACTION
X-ray结晶条件 VAPOR DIFFUSION, SITTING DROP；pH 7；297 K；Peg 2000, Bis-tris, pH 7.0, VAPOR DIFFUSION, SITTING DROP, temperature 297K
分辨率 3.10 Å R-free 0.300
3EH4 Structure of the reduced form of cytochrome ba3 oxidase from Thermus thermophilus 提交 2008-09-11 构建体不同 突变/修饰不同 配体/离子不同 实验环境不同 结构质量不同 Assembly 1 蛋白异源复合物 异源复合物；蛋白 × 3 PDB 声明：trimeric
链 A 2–562（561 aa） 片段：UNP residues 2-562
突变：K258R CU1 COPPER (I) ION × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 CUA DINUCLEAR COPPER ION × 1 BNG nonyl beta-D-glucopyranoside × 1 X-RAY DIFFRACTION
X-ray结晶条件 VAPOR DIFFUSION, SITTING DROP；pH 7；297 K；Peg 2000, Bis-tris, pH 7.0, VAPOR DIFFUSION, SITTING DROP, temperature 297K
分辨率 2.90 Å R-free 0.268
3EH4 Structure of the reduced form of cytochrome ba3 oxidase from Thermus thermophilus 提交 2008-09-11 构建体不同 突变/修饰不同 聚集状态不同 配体/离子不同 实验环境不同 结构质量不同 Assembly 2 蛋白单体 单体；蛋白 × 1 PDB 声明：monomeric
链 A 2–562（561 aa） 片段：UNP residues 2-562
突变：K258R CU1 COPPER (I) ION × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 X-RAY DIFFRACTION
X-ray结晶条件 VAPOR DIFFUSION, SITTING DROP；pH 7；297 K；Peg 2000, Bis-tris, pH 7.0, VAPOR DIFFUSION, SITTING DROP, temperature 297K
分辨率 2.90 Å R-free 0.268
3EH5 Structure of the reduced form of cytochrome ba3 oxidase from Thermus thermophilus 提交 2008-09-11 构建体不同 突变/修饰不同 配体/离子不同 实验环境不同 结构质量不同 Assembly 1 蛋白异源复合物 异源复合物；蛋白 × 3 PDB 声明：trimeric
链 A 2–562（561 aa） 片段：UNP residues 2-562
突变：K258R CU1 COPPER (I) ION × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 BNG nonyl beta-D-glucopyranoside × 4 CUA DINUCLEAR COPPER ION × 1 X-RAY DIFFRACTION
X-ray结晶条件 VAPOR DIFFUSION, SITTING DROP；pH 7；297 K；Peg 2000, Bis-tris, pH 7.0, VAPOR DIFFUSION, SITTING DROP, temperature 297K
分辨率 2.80 Å R-free 0.257
3EH5 Structure of the reduced form of cytochrome ba3 oxidase from Thermus thermophilus 提交 2008-09-11 构建体不同 突变/修饰不同 聚集状态不同 配体/离子不同 实验环境不同 结构质量不同 Assembly 2 蛋白单体 单体；蛋白 × 1 PDB 声明：monomeric
链 A 2–562（561 aa） 片段：UNP residues 2-562
突变：K258R CU1 COPPER (I) ION × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 BNG nonyl beta-D-glucopyranoside × 3 X-RAY DIFFRACTION
X-ray结晶条件 VAPOR DIFFUSION, SITTING DROP；pH 7；297 K；Peg 2000, Bis-tris, pH 7.0, VAPOR DIFFUSION, SITTING DROP, temperature 297K
分辨率 2.80 Å R-free 0.257
3QJQ The structure of and photolytic induced changes of carbon monoxide binding to the cytochrome ba3-oxidase from Thermus thermophilus 提交 2011-01-30 突变/修饰不同 配体/离子不同 实验环境不同 结构质量不同 Assembly 1 蛋白异源复合物 异源复合物；蛋白 × 3 PDB 声明：trimeric
链 A 2–562（561 aa）
未记录 CU1 COPPER (I) ION × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 CMO CARBON MONOXIDE × 1 CUA DINUCLEAR COPPER ION × 1 X-RAY DIFFRACTION
X-ray结晶条件 VAPOR DIFFUSION, SITTING DROP；pH 7；297 K；7% PEK 2K, 50 mM KCl, 20 mM Bis-Tris pH 7.0, 6.5 mM n-nonyl-beta-D glucopyranoside, VAPOR DIFFUSION, SITTING DROP, temperature 297K
分辨率 2.90 Å R-free 0.284
3QJR The structure of and photolytic induced changes of carbon monoxide binding to the cytochrome ba3-oxidase from Thermus thermophilus 提交 2011-01-30 突变/修饰不同 配体/离子不同 实验环境不同 结构质量不同 Assembly 1 蛋白异源复合物 异源复合物；蛋白 × 3 PDB 声明：trimeric
链 A 2–562（561 aa）
未记录 CU1 COPPER (I) ION × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 CMO CARBON MONOXIDE × 1 CUA DINUCLEAR COPPER ION × 1 X-RAY DIFFRACTION
X-ray结晶条件 VAPOR DIFFUSION, SITTING DROP；pH 7；297 K；7% PEK 2K, 50 mM KCl, 20 mM Bis-Tris pH 7.0, 6.5 mM n-nonyl-beta-D-glucopyranoside , VAPOR DIFFUSION, SITTING DROP, temperature 297K
分辨率 3.20 Å R-free 0.367
3QJS The structure of and photolytic induced changes of carbon monoxide binding to the cytochrome ba3-oxidase from Thermus thermophilus 提交 2011-01-30 突变/修饰不同 配体/离子不同 实验环境不同 结构质量不同 Assembly 1 蛋白异源复合物 异源复合物；蛋白 × 3 PDB 声明：trimeric
链 A 2–562（561 aa）
未记录 CU1 COPPER (I) ION × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 CMO CARBON MONOXIDE × 1 CUA DINUCLEAR COPPER ION × 1 X-RAY DIFFRACTION
X-ray结晶条件 VAPOR DIFFUSION, SITTING DROP；pH 7；297 K；7% PEK 2K, 50 mM KCl, 20 mM Bis-Tris pH 7.0, 6.5 mM n-nonyl-beta-D-glucopyranoside , VAPOR DIFFUSION, SITTING DROP, temperature 297K
分辨率 2.80 Å R-free 0.265
3QJT The structure of and photolytic induced changes of carbon monoxide binding to the cytochrome ba3-oxidase from Thermus thermophilus 提交 2011-01-30 突变/修饰不同 配体/离子不同 实验环境不同 结构质量不同 Assembly 1 蛋白异源复合物 异源复合物；蛋白 × 3 PDB 声明：trimeric
链 A 2–562（561 aa）
未记录 CU1 COPPER (I) ION × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 CMO CARBON MONOXIDE × 1 CUA DINUCLEAR COPPER ION × 1 X-RAY DIFFRACTION
X-ray结晶条件 VAPOR DIFFUSION, SITTING DROP；pH 7；297 K；7% PEK 2K, 50 mM KCl, 20 mM Bis-Tris pH 7.0, 6.5 mM n-nonyl-beta-D-glucopyranoside , VAPOR DIFFUSION, SITTING DROP, temperature 297K
分辨率 2.95 Å R-free 0.323
3QJU The structure of and photolytic induced changes of carbon monoxide binding to the cytochrome ba3-oxidase from Thermus thermophilus 提交 2011-01-30 突变/修饰不同 配体/离子不同 实验环境不同 结构质量不同 Assembly 1 蛋白异源复合物 异源复合物；蛋白 × 3 PDB 声明：trimeric
链 A 2–562（561 aa）
未记录 CU1 COPPER (I) ION × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 CMO CARBON MONOXIDE × 1 CUA DINUCLEAR COPPER ION × 1 X-RAY DIFFRACTION
X-ray结晶条件 VAPOR DIFFUSION, SITTING DROP；pH 7；297 K；7% PEK 2K, 50 mM KCl, 20 mM Bis-Tris pH 7.0, 6.5 mM n-nonyl-beta-D-glucopyranoside, VAPOR DIFFUSION, SITTING DROP, temperature 297K
分辨率 2.90 Å R-free 0.329
3QJV The structure of and photolytic induced changes of carbon monoxide binding to the cytochrome ba3-oxidase from Thermus thermophilus 提交 2011-01-30 突变/修饰不同 配体/离子不同 实验环境不同 结构质量不同 Assembly 1 蛋白异源复合物 异源复合物；蛋白 × 3 PDB 声明：trimeric
链 A 2–562（561 aa）
未记录 CU1 COPPER (I) ION × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 CMO CARBON MONOXIDE × 1 CUA DINUCLEAR COPPER ION × 1 X-RAY DIFFRACTION
X-ray结晶条件 VAPOR DIFFUSION, SITTING DROP；pH 7；297 K；7% PEK 2K, 50 mM KCl, 20 mM Bis-Tris pH 7.0, 6.5 mM n-nonyl-beta-D-glucopyranoside, VAPOR DIFFUSION, SITTING DROP, temperature 297K
分辨率 2.80 Å R-free 0.274
3S33 Structure of Thermus thermophilus cytochrome ba3 oxidase 10s after Xe depressurization 提交 2011-05-17 突变/修饰不同 配体/离子不同 实验环境不同 结构质量不同 Assembly 1 蛋白异源复合物 异源复合物；蛋白 × 3 PDB 声明：trimeric
链 A 2–562（561 aa）
未记录 CU COPPER (II) ION × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 XE XENON × 5 CUA DINUCLEAR COPPER ION × 1 X-RAY DIFFRACTION
X-ray结晶条件 VAPOR DIFFUSION, HANGING DROP；pH 7；297 K；12-17% PEG 2000, 0-200mM KCl, 15-60mM bis-Tris pH 7.0, 6.5mM nonyl-B-D-glucopyranoside, vapor diffusion, hanging drop, temperature 297K
分辨率 4.45 Å R-free 0.350
3S38 Structure of Thermus thermophilus cytochrome ba3 oxidase 30s after Xe depressurization 提交 2011-05-17 突变/修饰不同 配体/离子不同 实验环境不同 结构质量不同 Assembly 1 蛋白异源复合物 异源复合物；蛋白 × 3 PDB 声明：trimeric
链 A 2–562（561 aa）
未记录 CU COPPER (II) ION × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 XE XENON × 4 CUA DINUCLEAR COPPER ION × 1 X-RAY DIFFRACTION
X-ray结晶条件 VAPOR DIFFUSION, HANGING DROP；pH 7；297 K；12-17% PEG 2000, 0-200mM KCl, 15-60mM bis-Tris pH 7.0, 6.5mM nonyl-B-D-glucopyranoside, vapor diffusion, hanging drop, temperature 297K
分辨率 4.20 Å R-free 0.325
3S39 Structure of Thermus thermophilus cytochrome ba3 oxidase 60s after Xe depressurization 提交 2011-05-17 突变/修饰不同 配体/离子不同 实验环境不同 结构质量不同 Assembly 1 蛋白异源复合物 异源复合物；蛋白 × 3 PDB 声明：trimeric
链 A 2–562（561 aa）
未记录 CU COPPER (II) ION × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 XE XENON × 4 CUA DINUCLEAR COPPER ION × 1 X-RAY DIFFRACTION
X-ray结晶条件 VAPOR DIFFUSION, HANGING DROP；pH 7；297 K；12-17% PEG 2000, 0-200mM KCl, 15-60mM bis-Tris pH 7.0, 6.5mM nonyl-B-D-glucopyranoside, vapor diffusion, hanging drop, temperature 297K
分辨率 4.80 Å R-free 0.341
3S3A Structure of Thermus thermophilus cytochrome ba3 oxidase 120s after Xe depressurization 提交 2011-05-18 突变/修饰不同 配体/离子不同 实验环境不同 结构质量不同 Assembly 1 蛋白异源复合物 异源复合物；蛋白 × 3 PDB 声明：trimeric
链 A 2–562（561 aa）
未记录 CU COPPER (II) ION × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 XE XENON × 4 CUA DINUCLEAR COPPER ION × 1 X-RAY DIFFRACTION
X-ray结晶条件 VAPOR DIFFUSION, HANGING DROP；pH 7；297 K；12-17% PEG 2000, 0-200mM KCl, 15-60mM bis-Tris pH 7.0, 6.5mM nonyl-B-D-glucopyranoside, vapor diffusion, hanging drop, temperature 297K
分辨率 4.25 Å R-free 0.330
3S3B Structure of Thermus thermophilus cytochrome ba3 oxidase 240s after Xe depressurization 提交 2011-05-18 突变/修饰不同 配体/离子不同 实验环境不同 结构质量不同 Assembly 1 蛋白异源复合物 异源复合物；蛋白 × 3 PDB 声明：trimeric
链 A 2–562（561 aa）
未记录 CU COPPER (II) ION × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 XE XENON × 3 CUA DINUCLEAR COPPER ION × 1 X-RAY DIFFRACTION
X-ray结晶条件 VAPOR DIFFUSION, HANGING DROP；pH 7；297 K；12-17% PEG 2000, 0-200mM KCl, 15-60mM bis-Tris pH 7.0, 6.5mM nonyl-B-D-glucopyranoside, vapor diffusion, hanging drop, temperature 297K
分辨率 3.30 Å R-free 0.299
3S3C Structure of Thermus thermophilus cytochrome ba3 oxidase 360s after Xe depressurization 提交 2011-05-18 突变/修饰不同 配体/离子不同 实验环境不同 结构质量不同 Assembly 1 蛋白异源复合物 异源复合物；蛋白 × 3 PDB 声明：trimeric
链 A 2–562（561 aa）
未记录 CU COPPER (II) ION × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 XE XENON × 3 CUA DINUCLEAR COPPER ION × 1 X-RAY DIFFRACTION
X-ray结晶条件 pH 7；297 K；12-17% PEG 2000, 0-200mM KCl, 15-60mM bis-Tris pH 7.0, 6.5mM nonyl-B-D-glucopyranoside, vapor diffusion, hanging drop, temperature 297K
分辨率 4.00 Å R-free 0.373
3S3D Structure of Thermus thermophilus cytochrome ba3 oxidase 480s after Xe depressurization 提交 2011-05-18 突变/修饰不同 配体/离子不同 实验环境不同 结构质量不同 Assembly 1 蛋白异源复合物 异源复合物；蛋白 × 3 PDB 声明：trimeric
链 A 2–562（561 aa）
未记录 CU COPPER (II) ION × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 XE XENON × 3 CUA DINUCLEAR COPPER ION × 1 X-RAY DIFFRACTION
X-ray结晶条件 pH 7；297 K；12-17% PEG 2000, 0-200mM KCl, 15-60mM bis-Tris pH 7.0, 6.5mM nonyl-B-D-glucopyranoside, vapor diffusion, hanging drop, temperature 297K
分辨率 3.75 Å R-free 0.293
3S8F 1.8 A structure of ba3 cytochrome c oxidase from Thermus thermophilus in lipid environment 提交 2011-05-27 突变/修饰不同 实验环境不同 结构质量不同 Assembly 1 蛋白异源复合物 异源复合物；蛋白 × 3 PDB 声明：trimeric
链 A 2–562（561 aa）
未记录 CU COPPER (II) ION × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 PER PEROXIDE ION × 1 OLC (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate × 16 CUA DINUCLEAR COPPER ION × 1 X-RAY DIFFRACTION
X-ray结晶条件 LIPIDIC CUBIC PHASE；pH 6；293 K；40-45% PEG 400, 1.0-1.6M NaCl, 100mM sodium cacodylate trihydrate pH 5.5-6.5, lipidic cubic phase with monolein, temperature 293K
分辨率 1.80 Å R-free 0.215
3S8G 1.8 A structure of ba3 cytochrome c oxidase mutant (A120F) from Thermus thermophilus in lipid environment 提交 2011-05-27 突变/修饰不同 配体/离子不同 实验环境不同 结构质量不同 Assembly 1 蛋白异源复合物 异源复合物；蛋白 × 3 PDB 声明：trimeric
链 A 2–562（561 aa）
未记录 HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 CU COPPER (II) ION × 1 PER PEROXIDE ION × 1 OLC (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate × 20 CUA DINUCLEAR COPPER ION × 1 X-RAY DIFFRACTION
X-ray结晶条件 LIPIDIC CUBIC PHASE；293 K；40-45% PEG 400, 1.0-1.6M NaCl, 100mM sodium cacodylate trihydrate pH 5.5-6.5, lipidic cubic phase with monolein, temperature 293K
分辨率 1.80 Å R-free 0.196
4FA7 Structure of Recombinant Cytochrome ba3 Oxidase mutant A204F from Thermus thermophilus 提交 2012-05-21 突变/修饰不同 配体/离子不同 结构质量不同 Assembly 1 蛋白异源复合物 异源复合物；蛋白 × 3 PDB 声明：trimeric
链 A 2–562（561 aa）
突变：A204F CU COPPER (II) ION × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 PEO HYDROGEN PEROXIDE × 1 OLC (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate × 16 CUA DINUCLEAR COPPER ION × 1 X-RAY DIFFRACTION
X-ray结晶条件 LIPIDIC CUBIC PHASE；pH 6.5；293 K；50mM Sodium Cacodylate, 1.6M NaCl, 40% PEG400, pH 6.5, Lipidic Cubic Phase, temperature 293K
分辨率 2.50 Å R-free 0.220
4FAA Structure of Recombinant Cytochrome ba3 Oxidase mutant A120F+A204F from Thermus thermophilus 提交 2012-05-21 突变/修饰不同 配体/离子不同 结构质量不同 Assembly 1 蛋白异源复合物 异源复合物；蛋白 × 3 PDB 声明：trimeric
链 A 2–562（561 aa）
突变：Y120F,204F CU COPPER (II) ION × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 PEO HYDROGEN PEROXIDE × 1 OLC (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate × 16 CUA DINUCLEAR COPPER ION × 1 X-RAY DIFFRACTION
X-ray结晶条件 LIPIDIC CUBIC PHASE；pH 6.5；293 K；50mM Sodium Cacodylate, 1.6M NaCl, 40% PEG400, pH 6.5, Lipidic Cubic Phase, temperature 293K
分辨率 2.80 Å R-free 0.254
4G70 Structure of Recombinant Cytochrome ba3 Oxidase mutant V236T from Thermus thermophilus 提交 2012-07-19 突变/修饰不同 实验环境不同 结构质量不同 Assembly 1 蛋白异源复合物 异源复合物；蛋白 × 3 PDB 声明：trimeric
链 A 2–562（561 aa）
突变：A120F, V236T HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 CU COPPER (II) ION × 1 PER PEROXIDE ION × 1 OLC (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate × 16 CUA DINUCLEAR COPPER ION × 1 X-RAY DIFFRACTION
X-ray结晶条件 LIPIDIC CUBIC PHASE；pH 6.5；293 K；50mM Sodium Cacodylate PH 6.5, 1.6M NaCl, 40% PEG400 , Lipidic Cubic Phase, temperature 293K
分辨率 2.60 Å R-free 0.252
4G71 Structure of Recombinant Cytochrome ba3 Oxidase mutant V236N from Thermus thermophilus 提交 2012-07-19 突变/修饰不同 配体/离子不同 实验环境不同 结构质量不同 Assembly 1 蛋白异源复合物 异源复合物；蛋白 × 3 PDB 声明：trimeric
链 A 2–562（561 aa）
突变：A120F, V236N CUB CU(I)-S-MO(IV)(=O)O-NBIC CLUSTER × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 PER PEROXIDE ION × 1 OLC (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate × 16 CUA DINUCLEAR COPPER ION × 1 X-RAY DIFFRACTION
X-ray结晶条件 LIPIDIC CUBIC PHASE；pH 6.5；293 K；50mM Sodium Cacodylate PH 6.5, 1.6M NaCl, 40% PEG400 , Lipidic Cubic Phase, temperature 293K
分辨率 2.90 Å R-free 0.224
4G72 Structure of Recombinant Cytochrome ba3 Oxidase mutant V236M from Thermus thermophilus 提交 2012-07-19 突变/修饰不同 实验环境不同 结构质量不同 Assembly 1 蛋白异源复合物 异源复合物；蛋白 × 3 PDB 声明：trimeric
链 A 2–562（561 aa）
突变：A120F, V236M CU COPPER (II) ION × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 PER PEROXIDE ION × 1 OLC (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate × 16 CUA DINUCLEAR COPPER ION × 1 X-RAY DIFFRACTION
X-ray结晶条件 LIPIDIC CUBIC PHASE；pH 6.5；293 K；50mM Sodium Cacodylate PH 6.5, 1.6M NaCl, 40% PEG400 , Lipidic Cubic Phase, temperature 293K
分辨率 3.19 Å R-free 0.223
4G7Q Structure of Recombinant Cytochrome ba3 Oxidase mutant V236L from Thermus thermophilus 提交 2012-07-20 突变/修饰不同 实验环境不同 结构质量不同 Assembly 1 蛋白异源复合物 异源复合物；蛋白 × 3 PDB 声明：trimeric
链 A 2–562（561 aa）
突变：A120F, V236L CU COPPER (II) ION × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 PER PEROXIDE ION × 1 OLC (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate × 16 CUA DINUCLEAR COPPER ION × 1 X-RAY DIFFRACTION
X-ray结晶条件 LIPIDIC CUBIC PHASE；pH 6.5；293 K；50mM Sodium Cacodylate PH 6.5, 1.6M NaCl, 40% PEG400 , Lipidic Cubic Phase, temperature 293K
分辨率 2.60 Å R-free 0.232
4G7R Structure of Recombinant Cytochrome ba3 Oxidase mutant V236A from Thermus thermophilus 提交 2012-07-20 突变/修饰不同 配体/离子不同 实验环境不同 结构质量不同 Assembly 1 蛋白异源复合物 异源复合物；蛋白 × 3 PDB 声明：trimeric
链 A 2–562（561 aa）
突变：A120F, V236A CU COPPER (II) ION × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 PER PEROXIDE ION × 1 OLC (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate × 15 CUA DINUCLEAR COPPER ION × 1 X-RAY DIFFRACTION mmCIF 未提供已读取条件 分辨率 3.05 Å R-free 0.231
4G7S Structure of Recombinant Cytochrome ba3 Oxidase mutant V236I from Thermus thermophilus 提交 2012-07-20 突变/修饰不同 配体/离子不同 实验环境不同 结构质量不同 Assembly 1 蛋白异源复合物 异源复合物；蛋白 × 3 PDB 声明：trimeric
链 A 2–562（561 aa）
突变：A120F, V236I CU COPPER (II) ION × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 PER PEROXIDE ION × 1 OLC (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate × 15 CUA DINUCLEAR COPPER ION × 1 X-RAY DIFFRACTION
X-ray结晶条件 LIPIDIC CUBIC PHASE；pH 6.5；293 K；50mM Sodium Cacodylate PH 6.5, 1.6M NaCl, 40% PEG400 , Lipidic Cubic Phase, temperature 293K
分辨率 2.00 Å R-free 0.207
4GP5 Structure of Recombinant Cytochrome ba3 Oxidase mutant Y133W from Thermus thermophilus 提交 2012-08-20 突变/修饰不同 结构质量不同 Assembly 1 蛋白异源复合物 异源复合物；蛋白 × 3 PDB 声明：trimeric
链 A 2–562（561 aa）
突变：Y133W CU COPPER (II) ION × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 PER PEROXIDE ION × 1 OLC (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate × 16 CUA DINUCLEAR COPPER ION × 1 X-RAY DIFFRACTION
X-ray结晶条件 LIPIDIC CUBIC PHASE；pH 6.5；293 K；50mM Sodium Cacodylate, 1.6M NaCl, 40% PEG400, pH 6.5, Lipidic Cubic Phase, temperature 293K
分辨率 2.70 Å R-free 0.230
4GP8 Structure of Recombinant Cytochrome ba3 Oxidase mutant Y133W+T231F from Thermus thermophilus 提交 2012-08-20 突变/修饰不同 结构质量不同 Assembly 1 蛋白异源复合物 异源复合物；蛋白 × 3 PDB 声明：trimeric
链 A 2–562（561 aa）
突变：Y133W, T231F CU COPPER (II) ION × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 PER PEROXIDE ION × 1 OLC (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate × 16 CUA DINUCLEAR COPPER ION × 1 X-RAY DIFFRACTION
X-ray结晶条件 LIPIDIC CUBIC PHASE；pH 6.5；293 K；50mM Sodium Cacodylate, 1.6M NaCl, 40% PEG400, pH 6.5, Lipidic Cubic Phase, temperature 293K
分辨率 2.80 Å R-free 0.227
4N4Y Structure of Recombinant Cytochrome ba3 Oxidase mutant G232V from Thermus thermophilus 提交 2013-10-08 突变/修饰不同 配体/离子不同 实验环境不同 结构质量不同 Assembly 1 蛋白异源复合物 异源复合物；蛋白 × 3 PDB 声明：trimeric
链 A 2–562（561 aa）
突变：G232V CU COPPER (II) ION × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 PEO HYDROGEN PEROXIDE × 1 OLC (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate × 16 CUA DINUCLEAR COPPER ION × 1 X-RAY DIFFRACTION
X-ray结晶条件 LIPIDIC CUBIC PHASE；pH 6.5；293 K；50 mM sodium cacodylate, pH 6.5, 1.6 M sodium chloride, 40% PEG400, LIPIDIC CUBIC PHASE, temperature 293K
分辨率 2.90 Å R-free 0.225
5NDC Structure of ba3-type cytochrome c oxidase from Thermus thermophilus by serial femtosecond crystallography 提交 2017-03-08 突变/修饰不同 配体/离子不同 实验环境不同 结构质量不同 Assembly 1 蛋白异源复合物 异源复合物；蛋白 × 3 PDB 声明：trimeric
链 A 2–562（561 aa）
未记录 CU COPPER (II) ION × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 OLC (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate × 15 CUA DINUCLEAR COPPER ION × 1 X-RAY DIFFRACTION
X-ray结晶条件 LIPIDIC CUBIC PHASE；pH 5.3；293 K；100mM sodium cacodylate trihydrate pH 5.3, 37% PEG400, 1.4M NaCl Room temperature for 2-3 days
分辨率 2.30 Å R-free 0.197
8AJZ Serial femtosecond crystallography structure of CO bound ba3- type cytochrome c oxidase at 2 milliseconds after irradiation by a 532 nm laser 提交 2022-07-29 突变/修饰不同 配体/离子不同 实验环境不同 结构质量不同 Assembly 1 蛋白异源复合物 异源复合物；蛋白 × 3 PDB 声明：trimeric
链 A 2–562（561 aa）
未记录 CU COPPER (II) ION × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 OLC (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate × 15 CMO CARBON MONOXIDE × 1 CUA DINUCLEAR COPPER ION × 1 X-RAY DIFFRACTION
X-ray结晶条件 LIPIDIC CUBIC PHASE；pH 5.3；298 K；100 mM 2-Morpholinoethanesulfonic acid, 34-38 % PEG 400 (v/v), 1.4 M NaCl, pH 5.3
分辨率 2.00 Å R-free 0.210
8HUA Serial synchrotron crystallography structure of ba3-type cytochrome c oxidase from Thermus thermophilus using a goniometer compatible flow-cell 提交 2022-12-22 突变/修饰不同 配体/离子不同 实验环境不同 结构质量不同 Assembly 1 蛋白异源复合物 异源复合物；蛋白 × 3 PDB 声明：trimeric
链 A 2–562（561 aa）
未记录 CU COPPER (II) ION × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 OLC (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate × 15 CUA DINUCLEAR COPPER ION × 1 X-RAY DIFFRACTION
X-ray结晶条件 LIPIDIC CUBIC PHASE；pH 5.3；298 K；1.4 M NaCl, 100 mM MES pH 5.3 with 36 % to 39 % (v/v) PEG 400
分辨率 2.12 Å R-free 0.184
8K65 Serial femtosecond crystallography structure of CO bound ba3- type cytochrome c oxidase without pump laser irradiation 提交 2023-07-25 突变/修饰不同 配体/离子不同 实验环境不同 结构质量不同 Assembly 1 蛋白异源复合物 异源复合物；蛋白 × 3 PDB 声明：trimeric
链 A 2–562（561 aa）
未记录 CU COPPER (II) ION × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 OLC (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate × 15 CMO CARBON MONOXIDE × 1 CUA DINUCLEAR COPPER ION × 1 X-RAY DIFFRACTION
X-ray结晶条件 LIPIDIC CUBIC PHASE；pH 5.3；293 K；34-38 % PEG 400 (v/v), 1.4 M NaCl, pH 5.3
分辨率 2.00 Å R-free 0.196
8K6Y Serial femtosecond crystallography structure of photo dissociated CO from ba3- type cytochrome c oxidase determined by extrapolation method 提交 2023-07-25 突变/修饰不同 配体/离子不同 实验环境不同 结构质量不同 Assembly 1 蛋白异源复合物 异源复合物；蛋白 × 3 PDB 声明：trimeric
链 A 2–562（561 aa）
未记录 CU COPPER (II) ION × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 OLC (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate × 15 CMO CARBON MONOXIDE × 1 CUA DINUCLEAR COPPER ION × 1 X-RAY DIFFRACTION
X-ray结晶条件 LIPIDIC CUBIC PHASE；pH 5.3；293 K；34-38 % PEG 400 (v/v), 1.4 M NaCl, pH 5.3
分辨率 2.00 Å R-free 0.435
9GDF Chloride bound structure of oxidized ba3-type cytochrome c oxidase confirmed by single-wavelength anomalous diffraction 提交 2024-08-05 突变/修饰不同 配体/离子不同 实验环境不同 结构质量不同 Assembly 1 蛋白异源复合物 异源复合物；蛋白 × 3 PDB 声明：trimeric
链 A 2–562（561 aa）
未记录 CU COPPER (II) ION × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 OLC (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate × 15 CL CHLORIDE ION × 2 CUA DINUCLEAR COPPER ION × 1 X-RAY DIFFRACTION
X-ray结晶条件 LIPIDIC CUBIC PHASE；pH 5.3；298 K；1.4 M NaCl, 100 mM MES. 40-43 % (v/v) PEG 400
分辨率 2.28 Å R-free 0.197
9VDJ Serial synchrotron crystallography structure of a ba3-type cytochrome c oxidase using a goniometer-compatible chip-based platform 提交 2025-06-08 突变/修饰不同 配体/离子不同 实验环境不同 结构质量不同 Assembly 1 蛋白异源复合物 异源复合物；蛋白 × 3 PDB 声明：trimeric
链 A 2–562（561 aa）
未记录 CU COPPER (II) ION × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 OLC (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate × 15 CUA DINUCLEAR COPPER ION × 1 X-RAY DIFFRACTION
X-ray结晶条件 LIPIDIC CUBIC PHASE；293 K；0.1M MES (pH 5.3), 1.4M NaCl, 39-41% PEG 400
分辨率 2.30 Å R-free 0.264

共 40 个其他 PDB 条目、43 个 assembly。 打开独立比较页并筛选聚集状态

查看构建体与数据证据
UniProt名称 COX1_THET8
Isoform —
PDB实体 1
链与序列区间 作者链 A； PDB构建体 8–568； UniProt 2–562

Cytochrome c oxidase subunit 2

Thermus thermophilus

UniProt Q5SJ80

当前结构中的状态

Assembly 聚集状态 构建体 突变与修饰 配体、离子与共同组分 实验方法与环境 结构质量
1 蛋白异源复合物 异源复合物 蛋白 × 3 PDB 声明：trimeric（3） 与蛋白拷贝数一致 链 B； UniProt 1–168 未记录 Cytochrome c oxidase subunit 1 × 1 （Q5SJ79） Cytochrome c oxidase polypeptide 2A × 1 （P82543） CU COPPER (II) ION × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 PER PEROXIDE ION × 1 OLC (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate × 16 CUA DINUCLEAR COPPER ION × 1 X-RAY DIFFRACTION X-ray结晶条件：LIPIDIC CUBIC PHASE；pH 6.5；293 K；50mM Sodium Cacodylate, 1.6M NaCl, 40% PEG400, pH 6.5, Lipidic Cubic Phase, temperature 293K 分辨率 2.80 Å R-free 0.227

数据库中的同蛋白其他状态

以下每一行都是同一 UniProt 蛋白在另一个 PDB 条目中的 biological assembly， “相对当前条目”直接指出证据层面的不同；没有差异标签表示当前已读取字段一致。

其他 PDB 相对当前条目 4GP4 Assembly / 聚集状态 构建体 突变与修饰 配体、离子与非聚合物 实验方法与环境 结构质量
1EHK CRYSTAL STRUCTURE OF THE ABERRANT BA3-CYTOCHROME-C OXIDASE FROM THERMUS THERMOPHILUS 提交 2000-02-21 构建体不同 配体/离子不同 实验环境不同 结构质量不同 Assembly 1 蛋白异源复合物 异源复合物；蛋白 × 3 PDB 声明：trimeric
链 B 1–168（168 aa） 片段：SUBUNIT II
未记录 BNG nonyl beta-D-glucopyranoside × 3 CU COPPER (II) ION × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 CUA DINUCLEAR COPPER ION × 1 X-RAY DIFFRACTION
X-ray结晶条件 VAPOR DIFFUSION, SITTING DROP；pH 7；293 K；PEG 2000, Bis-Tris buffer, nonyl-beta-D-glucoside, pH 7.0, VAPOR DIFFUSION, SITTING DROP, temperature 293K
分辨率 2.40 Å R-free 0.264
2QPD An unexpected outcome of surface-engineering an integral membrane protein: Improved crystallization of cytochrome ba3 oxidase from Thermus thermophilus 提交 2007-07-23 配体/离子不同 实验环境不同 结构质量不同 Assembly 1 蛋白异源复合物 异源复合物；蛋白 × 3 PDB 声明：trimeric
链 B 1–168（168 aa）
未记录 CU1 COPPER (I) ION × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 CUA DINUCLEAR COPPER ION × 1 X-RAY DIFFRACTION
X-ray结晶条件 VAPOR DIFFUSION, SITTING DROP；pH 7；291 K；7% PEK 2K, 50 mM KCl, 20 mM Bis-Tris pH 7.0, 6.5 mM n-nonyl-beta-D-glucopyranoside, VAPOR DIFFUSION, SITTING DROP, temperature 291K
分辨率 3.25 Å R-free 0.307
2QPE An unexpected outcome of surface-engineering an integral membrane protein: Improved crystallization of cytochrome ba3 oxidase from Thermus thermophilus 提交 2007-07-23 突变/修饰不同 配体/离子不同 实验环境不同 结构质量不同 Assembly 1 蛋白异源复合物 异源复合物；蛋白 × 3 PDB 声明：trimeric
链 B 1–168（168 aa）
突变：E4Q CU1 COPPER (I) ION × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 CUA DINUCLEAR COPPER ION × 1 X-RAY DIFFRACTION
X-ray结晶条件 VAPOR DIFFUSION, SITTING DROP；pH 7；291 K；7% PEK 2K, 50 mM KCl, 20 mM Bis-Tris, pH 7.0, 6.5 mM n-nonyl-beta-D-glucopyranoside, VAPOR DIFFUSION, SITTING DROP, temperature 291K
分辨率 2.90 Å R-free 0.302
3BVD Structure of Surface-engineered Cytochrome ba3 Oxidase from Thermus thermophilus under Xenon Pressure, 100psi 5min 提交 2008-01-07 突变/修饰不同 配体/离子不同 实验环境不同 结构质量不同 Assembly 1 蛋白异源复合物 异源复合物；蛋白 × 3 PDB 声明：trimeric
链 B 1–168（168 aa）
突变：E4Q CU COPPER (II) ION × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 XE XENON × 7 CUA DINUCLEAR COPPER ION × 1 X-RAY DIFFRACTION
X-ray结晶条件 VAPOR DIFFUSION；pH 7；297 K；6-9% PEG 2000, 50mM KCl, 7.5-30mM bis-Tris pH 7.0, 6.5mM nonyl-B-D-glucopyranoside , VAPOR DIFFUSION, temperature 297K
分辨率 3.37 Å R-free 0.336
3EH3 Structure of the reduced form of cytochrome ba3 oxidase from Thermus thermophilus 提交 2008-09-11 构建体不同 突变/修饰不同 配体/离子不同 实验环境不同 结构质量不同 Assembly 1 蛋白异源复合物 异源复合物；蛋白 × 3 PDB 声明：trimeric
链 B 3–168（166 aa） 片段：UNP residues 3-168
突变：E4Q CU1 COPPER (I) ION × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 CUA DINUCLEAR COPPER ION × 1 X-RAY DIFFRACTION
X-ray结晶条件 VAPOR DIFFUSION, SITTING DROP；pH 7；297 K；Peg 2000, Bis-tris, pH 7.0, VAPOR DIFFUSION, SITTING DROP, temperature 297K
分辨率 3.10 Å R-free 0.300
3EH3 Structure of the reduced form of cytochrome ba3 oxidase from Thermus thermophilus 提交 2008-09-11 构建体不同 突变/修饰不同 聚集状态不同 配体/离子不同 实验环境不同 结构质量不同 Assembly 3 蛋白单体 单体；蛋白 × 1 PDB 声明：monomeric
链 B 3–168（166 aa） 片段：UNP residues 3-168
突变：E4Q CUA DINUCLEAR COPPER ION × 1 X-RAY DIFFRACTION
X-ray结晶条件 VAPOR DIFFUSION, SITTING DROP；pH 7；297 K；Peg 2000, Bis-tris, pH 7.0, VAPOR DIFFUSION, SITTING DROP, temperature 297K
分辨率 3.10 Å R-free 0.300
3EH4 Structure of the reduced form of cytochrome ba3 oxidase from Thermus thermophilus 提交 2008-09-11 构建体不同 突变/修饰不同 配体/离子不同 实验环境不同 结构质量不同 Assembly 1 蛋白异源复合物 异源复合物；蛋白 × 3 PDB 声明：trimeric
链 B 3–168（166 aa） 片段：UNP residues 3-168
突变：E4Q CU1 COPPER (I) ION × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 CUA DINUCLEAR COPPER ION × 1 BNG nonyl beta-D-glucopyranoside × 1 X-RAY DIFFRACTION
X-ray结晶条件 VAPOR DIFFUSION, SITTING DROP；pH 7；297 K；Peg 2000, Bis-tris, pH 7.0, VAPOR DIFFUSION, SITTING DROP, temperature 297K
分辨率 2.90 Å R-free 0.268
3EH4 Structure of the reduced form of cytochrome ba3 oxidase from Thermus thermophilus 提交 2008-09-11 构建体不同 突变/修饰不同 聚集状态不同 配体/离子不同 实验环境不同 结构质量不同 Assembly 3 蛋白单体 单体；蛋白 × 1 PDB 声明：monomeric
链 B 3–168（166 aa） 片段：UNP residues 3-168
突变：E4Q CUA DINUCLEAR COPPER ION × 1 X-RAY DIFFRACTION
X-ray结晶条件 VAPOR DIFFUSION, SITTING DROP；pH 7；297 K；Peg 2000, Bis-tris, pH 7.0, VAPOR DIFFUSION, SITTING DROP, temperature 297K
分辨率 2.90 Å R-free 0.268
3EH5 Structure of the reduced form of cytochrome ba3 oxidase from Thermus thermophilus 提交 2008-09-11 构建体不同 突变/修饰不同 配体/离子不同 实验环境不同 结构质量不同 Assembly 1 蛋白异源复合物 异源复合物；蛋白 × 3 PDB 声明：trimeric
链 B 3–168（166 aa） 片段：UNP residues 3-168
突变：E4Q CU1 COPPER (I) ION × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 BNG nonyl beta-D-glucopyranoside × 4 CUA DINUCLEAR COPPER ION × 1 X-RAY DIFFRACTION
X-ray结晶条件 VAPOR DIFFUSION, SITTING DROP；pH 7；297 K；Peg 2000, Bis-tris, pH 7.0, VAPOR DIFFUSION, SITTING DROP, temperature 297K
分辨率 2.80 Å R-free 0.257
3EH5 Structure of the reduced form of cytochrome ba3 oxidase from Thermus thermophilus 提交 2008-09-11 构建体不同 突变/修饰不同 聚集状态不同 配体/离子不同 实验环境不同 结构质量不同 Assembly 3 蛋白单体 单体；蛋白 × 1 PDB 声明：monomeric
链 B 3–168（166 aa） 片段：UNP residues 3-168
突变：E4Q CUA DINUCLEAR COPPER ION × 1 X-RAY DIFFRACTION
X-ray结晶条件 VAPOR DIFFUSION, SITTING DROP；pH 7；297 K；Peg 2000, Bis-tris, pH 7.0, VAPOR DIFFUSION, SITTING DROP, temperature 297K
分辨率 2.80 Å R-free 0.257
3QJQ The structure of and photolytic induced changes of carbon monoxide binding to the cytochrome ba3-oxidase from Thermus thermophilus 提交 2011-01-30 配体/离子不同 实验环境不同 结构质量不同 Assembly 1 蛋白异源复合物 异源复合物；蛋白 × 3 PDB 声明：trimeric
链 B 1–168（168 aa）
未记录 CU1 COPPER (I) ION × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 CMO CARBON MONOXIDE × 1 CUA DINUCLEAR COPPER ION × 1 X-RAY DIFFRACTION
X-ray结晶条件 VAPOR DIFFUSION, SITTING DROP；pH 7；297 K；7% PEK 2K, 50 mM KCl, 20 mM Bis-Tris pH 7.0, 6.5 mM n-nonyl-beta-D glucopyranoside, VAPOR DIFFUSION, SITTING DROP, temperature 297K
分辨率 2.90 Å R-free 0.284
3QJR The structure of and photolytic induced changes of carbon monoxide binding to the cytochrome ba3-oxidase from Thermus thermophilus 提交 2011-01-30 配体/离子不同 实验环境不同 结构质量不同 Assembly 1 蛋白异源复合物 异源复合物；蛋白 × 3 PDB 声明：trimeric
链 B 1–168（168 aa）
未记录 CU1 COPPER (I) ION × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 CMO CARBON MONOXIDE × 1 CUA DINUCLEAR COPPER ION × 1 X-RAY DIFFRACTION
X-ray结晶条件 VAPOR DIFFUSION, SITTING DROP；pH 7；297 K；7% PEK 2K, 50 mM KCl, 20 mM Bis-Tris pH 7.0, 6.5 mM n-nonyl-beta-D-glucopyranoside , VAPOR DIFFUSION, SITTING DROP, temperature 297K
分辨率 3.20 Å R-free 0.367
3QJS The structure of and photolytic induced changes of carbon monoxide binding to the cytochrome ba3-oxidase from Thermus thermophilus 提交 2011-01-30 配体/离子不同 实验环境不同 结构质量不同 Assembly 1 蛋白异源复合物 异源复合物；蛋白 × 3 PDB 声明：trimeric
链 B 1–168（168 aa）
未记录 CU1 COPPER (I) ION × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 CMO CARBON MONOXIDE × 1 CUA DINUCLEAR COPPER ION × 1 X-RAY DIFFRACTION
X-ray结晶条件 VAPOR DIFFUSION, SITTING DROP；pH 7；297 K；7% PEK 2K, 50 mM KCl, 20 mM Bis-Tris pH 7.0, 6.5 mM n-nonyl-beta-D-glucopyranoside , VAPOR DIFFUSION, SITTING DROP, temperature 297K
分辨率 2.80 Å R-free 0.265
3QJT The structure of and photolytic induced changes of carbon monoxide binding to the cytochrome ba3-oxidase from Thermus thermophilus 提交 2011-01-30 配体/离子不同 实验环境不同 结构质量不同 Assembly 1 蛋白异源复合物 异源复合物；蛋白 × 3 PDB 声明：trimeric
链 B 1–168（168 aa）
未记录 CU1 COPPER (I) ION × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 CMO CARBON MONOXIDE × 1 CUA DINUCLEAR COPPER ION × 1 X-RAY DIFFRACTION
X-ray结晶条件 VAPOR DIFFUSION, SITTING DROP；pH 7；297 K；7% PEK 2K, 50 mM KCl, 20 mM Bis-Tris pH 7.0, 6.5 mM n-nonyl-beta-D-glucopyranoside , VAPOR DIFFUSION, SITTING DROP, temperature 297K
分辨率 2.95 Å R-free 0.323
3QJU The structure of and photolytic induced changes of carbon monoxide binding to the cytochrome ba3-oxidase from Thermus thermophilus 提交 2011-01-30 配体/离子不同 实验环境不同 结构质量不同 Assembly 1 蛋白异源复合物 异源复合物；蛋白 × 3 PDB 声明：trimeric
链 B 1–168（168 aa）
未记录 CU1 COPPER (I) ION × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 CMO CARBON MONOXIDE × 1 CUA DINUCLEAR COPPER ION × 1 X-RAY DIFFRACTION
X-ray结晶条件 VAPOR DIFFUSION, SITTING DROP；pH 7；297 K；7% PEK 2K, 50 mM KCl, 20 mM Bis-Tris pH 7.0, 6.5 mM n-nonyl-beta-D-glucopyranoside, VAPOR DIFFUSION, SITTING DROP, temperature 297K
分辨率 2.90 Å R-free 0.329
3QJV The structure of and photolytic induced changes of carbon monoxide binding to the cytochrome ba3-oxidase from Thermus thermophilus 提交 2011-01-30 配体/离子不同 实验环境不同 结构质量不同 Assembly 1 蛋白异源复合物 异源复合物；蛋白 × 3 PDB 声明：trimeric
链 B 1–168（168 aa）
未记录 CU1 COPPER (I) ION × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 CMO CARBON MONOXIDE × 1 CUA DINUCLEAR COPPER ION × 1 X-RAY DIFFRACTION
X-ray结晶条件 VAPOR DIFFUSION, SITTING DROP；pH 7；297 K；7% PEK 2K, 50 mM KCl, 20 mM Bis-Tris pH 7.0, 6.5 mM n-nonyl-beta-D-glucopyranoside, VAPOR DIFFUSION, SITTING DROP, temperature 297K
分辨率 2.80 Å R-free 0.274
3S33 Structure of Thermus thermophilus cytochrome ba3 oxidase 10s after Xe depressurization 提交 2011-05-17 构建体不同 配体/离子不同 实验环境不同 结构质量不同 Assembly 1 蛋白异源复合物 异源复合物；蛋白 × 3 PDB 声明：trimeric
链 B 3–168（166 aa）
未记录 CU COPPER (II) ION × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 XE XENON × 5 CUA DINUCLEAR COPPER ION × 1 X-RAY DIFFRACTION
X-ray结晶条件 VAPOR DIFFUSION, HANGING DROP；pH 7；297 K；12-17% PEG 2000, 0-200mM KCl, 15-60mM bis-Tris pH 7.0, 6.5mM nonyl-B-D-glucopyranoside, vapor diffusion, hanging drop, temperature 297K
分辨率 4.45 Å R-free 0.350
3S38 Structure of Thermus thermophilus cytochrome ba3 oxidase 30s after Xe depressurization 提交 2011-05-17 构建体不同 配体/离子不同 实验环境不同 结构质量不同 Assembly 1 蛋白异源复合物 异源复合物；蛋白 × 3 PDB 声明：trimeric
链 B 3–168（166 aa）
未记录 CU COPPER (II) ION × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 XE XENON × 4 CUA DINUCLEAR COPPER ION × 1 X-RAY DIFFRACTION
X-ray结晶条件 VAPOR DIFFUSION, HANGING DROP；pH 7；297 K；12-17% PEG 2000, 0-200mM KCl, 15-60mM bis-Tris pH 7.0, 6.5mM nonyl-B-D-glucopyranoside, vapor diffusion, hanging drop, temperature 297K
分辨率 4.20 Å R-free 0.325
3S39 Structure of Thermus thermophilus cytochrome ba3 oxidase 60s after Xe depressurization 提交 2011-05-17 构建体不同 配体/离子不同 实验环境不同 结构质量不同 Assembly 1 蛋白异源复合物 异源复合物；蛋白 × 3 PDB 声明：trimeric
链 B 3–168（166 aa）
未记录 CU COPPER (II) ION × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 XE XENON × 4 CUA DINUCLEAR COPPER ION × 1 X-RAY DIFFRACTION
X-ray结晶条件 VAPOR DIFFUSION, HANGING DROP；pH 7；297 K；12-17% PEG 2000, 0-200mM KCl, 15-60mM bis-Tris pH 7.0, 6.5mM nonyl-B-D-glucopyranoside, vapor diffusion, hanging drop, temperature 297K
分辨率 4.80 Å R-free 0.341
3S3A Structure of Thermus thermophilus cytochrome ba3 oxidase 120s after Xe depressurization 提交 2011-05-18 构建体不同 配体/离子不同 实验环境不同 结构质量不同 Assembly 1 蛋白异源复合物 异源复合物；蛋白 × 3 PDB 声明：trimeric
链 B 3–168（166 aa）
未记录 CU COPPER (II) ION × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 XE XENON × 4 CUA DINUCLEAR COPPER ION × 1 X-RAY DIFFRACTION
X-ray结晶条件 VAPOR DIFFUSION, HANGING DROP；pH 7；297 K；12-17% PEG 2000, 0-200mM KCl, 15-60mM bis-Tris pH 7.0, 6.5mM nonyl-B-D-glucopyranoside, vapor diffusion, hanging drop, temperature 297K
分辨率 4.25 Å R-free 0.330
3S3B Structure of Thermus thermophilus cytochrome ba3 oxidase 240s after Xe depressurization 提交 2011-05-18 构建体不同 配体/离子不同 实验环境不同 结构质量不同 Assembly 1 蛋白异源复合物 异源复合物；蛋白 × 3 PDB 声明：trimeric
链 B 3–168（166 aa）
未记录 CU COPPER (II) ION × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 XE XENON × 3 CUA DINUCLEAR COPPER ION × 1 X-RAY DIFFRACTION
X-ray结晶条件 VAPOR DIFFUSION, HANGING DROP；pH 7；297 K；12-17% PEG 2000, 0-200mM KCl, 15-60mM bis-Tris pH 7.0, 6.5mM nonyl-B-D-glucopyranoside, vapor diffusion, hanging drop, temperature 297K
分辨率 3.30 Å R-free 0.299
3S3C Structure of Thermus thermophilus cytochrome ba3 oxidase 360s after Xe depressurization 提交 2011-05-18 构建体不同 配体/离子不同 实验环境不同 结构质量不同 Assembly 1 蛋白异源复合物 异源复合物；蛋白 × 3 PDB 声明：trimeric
链 B 3–168（166 aa）
未记录 CU COPPER (II) ION × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 XE XENON × 3 CUA DINUCLEAR COPPER ION × 1 X-RAY DIFFRACTION
X-ray结晶条件 pH 7；297 K；12-17% PEG 2000, 0-200mM KCl, 15-60mM bis-Tris pH 7.0, 6.5mM nonyl-B-D-glucopyranoside, vapor diffusion, hanging drop, temperature 297K
分辨率 4.00 Å R-free 0.373
3S3D Structure of Thermus thermophilus cytochrome ba3 oxidase 480s after Xe depressurization 提交 2011-05-18 构建体不同 配体/离子不同 实验环境不同 结构质量不同 Assembly 1 蛋白异源复合物 异源复合物；蛋白 × 3 PDB 声明：trimeric
链 B 3–168（166 aa）
未记录 CU COPPER (II) ION × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 XE XENON × 3 CUA DINUCLEAR COPPER ION × 1 X-RAY DIFFRACTION
X-ray结晶条件 pH 7；297 K；12-17% PEG 2000, 0-200mM KCl, 15-60mM bis-Tris pH 7.0, 6.5mM nonyl-B-D-glucopyranoside, vapor diffusion, hanging drop, temperature 297K
分辨率 3.75 Å R-free 0.293
3S8F 1.8 A structure of ba3 cytochrome c oxidase from Thermus thermophilus in lipid environment 提交 2011-05-27 实验环境不同 结构质量不同 Assembly 1 蛋白异源复合物 异源复合物；蛋白 × 3 PDB 声明：trimeric
链 B 1–168（168 aa）
未记录 CU COPPER (II) ION × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 PER PEROXIDE ION × 1 OLC (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate × 16 CUA DINUCLEAR COPPER ION × 1 X-RAY DIFFRACTION
X-ray结晶条件 LIPIDIC CUBIC PHASE；pH 6；293 K；40-45% PEG 400, 1.0-1.6M NaCl, 100mM sodium cacodylate trihydrate pH 5.5-6.5, lipidic cubic phase with monolein, temperature 293K
分辨率 1.80 Å R-free 0.215
3S8G 1.8 A structure of ba3 cytochrome c oxidase mutant (A120F) from Thermus thermophilus in lipid environment 提交 2011-05-27 配体/离子不同 实验环境不同 结构质量不同 Assembly 1 蛋白异源复合物 异源复合物；蛋白 × 3 PDB 声明：trimeric
链 B 1–168（168 aa）
未记录 HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 CU COPPER (II) ION × 1 PER PEROXIDE ION × 1 OLC (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate × 20 CUA DINUCLEAR COPPER ION × 1 X-RAY DIFFRACTION
X-ray结晶条件 LIPIDIC CUBIC PHASE；293 K；40-45% PEG 400, 1.0-1.6M NaCl, 100mM sodium cacodylate trihydrate pH 5.5-6.5, lipidic cubic phase with monolein, temperature 293K
分辨率 1.80 Å R-free 0.196
4FA7 Structure of Recombinant Cytochrome ba3 Oxidase mutant A204F from Thermus thermophilus 提交 2012-05-21 配体/离子不同 结构质量不同 Assembly 1 蛋白异源复合物 异源复合物；蛋白 × 3 PDB 声明：trimeric
链 B 1–168（168 aa）
未记录 CU COPPER (II) ION × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 PEO HYDROGEN PEROXIDE × 1 OLC (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate × 16 CUA DINUCLEAR COPPER ION × 1 X-RAY DIFFRACTION
X-ray结晶条件 LIPIDIC CUBIC PHASE；pH 6.5；293 K；50mM Sodium Cacodylate, 1.6M NaCl, 40% PEG400, pH 6.5, Lipidic Cubic Phase, temperature 293K
分辨率 2.50 Å R-free 0.220
4FAA Structure of Recombinant Cytochrome ba3 Oxidase mutant A120F+A204F from Thermus thermophilus 提交 2012-05-21 配体/离子不同 结构质量不同 Assembly 1 蛋白异源复合物 异源复合物；蛋白 × 3 PDB 声明：trimeric
链 B 1–168（168 aa）
未记录 CU COPPER (II) ION × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 PEO HYDROGEN PEROXIDE × 1 OLC (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate × 16 CUA DINUCLEAR COPPER ION × 1 X-RAY DIFFRACTION
X-ray结晶条件 LIPIDIC CUBIC PHASE；pH 6.5；293 K；50mM Sodium Cacodylate, 1.6M NaCl, 40% PEG400, pH 6.5, Lipidic Cubic Phase, temperature 293K
分辨率 2.80 Å R-free 0.254
4G70 Structure of Recombinant Cytochrome ba3 Oxidase mutant V236T from Thermus thermophilus 提交 2012-07-19 实验环境不同 结构质量不同 Assembly 1 蛋白异源复合物 异源复合物；蛋白 × 3 PDB 声明：trimeric
链 B 1–168（168 aa）
未记录 HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 CU COPPER (II) ION × 1 PER PEROXIDE ION × 1 OLC (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate × 16 CUA DINUCLEAR COPPER ION × 1 X-RAY DIFFRACTION
X-ray结晶条件 LIPIDIC CUBIC PHASE；pH 6.5；293 K；50mM Sodium Cacodylate PH 6.5, 1.6M NaCl, 40% PEG400 , Lipidic Cubic Phase, temperature 293K
分辨率 2.60 Å R-free 0.252
4G71 Structure of Recombinant Cytochrome ba3 Oxidase mutant V236N from Thermus thermophilus 提交 2012-07-19 配体/离子不同 实验环境不同 结构质量不同 Assembly 1 蛋白异源复合物 异源复合物；蛋白 × 3 PDB 声明：trimeric
链 B 1–168（168 aa）
未记录 CUB CU(I)-S-MO(IV)(=O)O-NBIC CLUSTER × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 PER PEROXIDE ION × 1 OLC (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate × 16 CUA DINUCLEAR COPPER ION × 1 X-RAY DIFFRACTION
X-ray结晶条件 LIPIDIC CUBIC PHASE；pH 6.5；293 K；50mM Sodium Cacodylate PH 6.5, 1.6M NaCl, 40% PEG400 , Lipidic Cubic Phase, temperature 293K
分辨率 2.90 Å R-free 0.224
4G72 Structure of Recombinant Cytochrome ba3 Oxidase mutant V236M from Thermus thermophilus 提交 2012-07-19 实验环境不同 结构质量不同 Assembly 1 蛋白异源复合物 异源复合物；蛋白 × 3 PDB 声明：trimeric
链 B 1–168（168 aa）
未记录 CU COPPER (II) ION × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 PER PEROXIDE ION × 1 OLC (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate × 16 CUA DINUCLEAR COPPER ION × 1 X-RAY DIFFRACTION
X-ray结晶条件 LIPIDIC CUBIC PHASE；pH 6.5；293 K；50mM Sodium Cacodylate PH 6.5, 1.6M NaCl, 40% PEG400 , Lipidic Cubic Phase, temperature 293K
分辨率 3.19 Å R-free 0.223
4G7Q Structure of Recombinant Cytochrome ba3 Oxidase mutant V236L from Thermus thermophilus 提交 2012-07-20 实验环境不同 结构质量不同 Assembly 1 蛋白异源复合物 异源复合物；蛋白 × 3 PDB 声明：trimeric
链 B 1–168（168 aa）
未记录 CU COPPER (II) ION × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 PER PEROXIDE ION × 1 OLC (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate × 16 CUA DINUCLEAR COPPER ION × 1 X-RAY DIFFRACTION
X-ray结晶条件 LIPIDIC CUBIC PHASE；pH 6.5；293 K；50mM Sodium Cacodylate PH 6.5, 1.6M NaCl, 40% PEG400 , Lipidic Cubic Phase, temperature 293K
分辨率 2.60 Å R-free 0.232
4G7R Structure of Recombinant Cytochrome ba3 Oxidase mutant V236A from Thermus thermophilus 提交 2012-07-20 配体/离子不同 实验环境不同 结构质量不同 Assembly 1 蛋白异源复合物 异源复合物；蛋白 × 3 PDB 声明：trimeric
链 B 1–168（168 aa）
未记录 CU COPPER (II) ION × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 PER PEROXIDE ION × 1 OLC (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate × 15 CUA DINUCLEAR COPPER ION × 1 X-RAY DIFFRACTION mmCIF 未提供已读取条件 分辨率 3.05 Å R-free 0.231
4G7S Structure of Recombinant Cytochrome ba3 Oxidase mutant V236I from Thermus thermophilus 提交 2012-07-20 配体/离子不同 实验环境不同 结构质量不同 Assembly 1 蛋白异源复合物 异源复合物；蛋白 × 3 PDB 声明：trimeric
链 B 1–168（168 aa）
未记录 CU COPPER (II) ION × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 PER PEROXIDE ION × 1 OLC (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate × 15 CUA DINUCLEAR COPPER ION × 1 X-RAY DIFFRACTION
X-ray结晶条件 LIPIDIC CUBIC PHASE；pH 6.5；293 K；50mM Sodium Cacodylate PH 6.5, 1.6M NaCl, 40% PEG400 , Lipidic Cubic Phase, temperature 293K
分辨率 2.00 Å R-free 0.207
4GP5 Structure of Recombinant Cytochrome ba3 Oxidase mutant Y133W from Thermus thermophilus 提交 2012-08-20 结构质量不同 Assembly 1 蛋白异源复合物 异源复合物；蛋白 × 3 PDB 声明：trimeric
链 B 1–168（168 aa）
未记录 CU COPPER (II) ION × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 PER PEROXIDE ION × 1 OLC (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate × 16 CUA DINUCLEAR COPPER ION × 1 X-RAY DIFFRACTION
X-ray结晶条件 LIPIDIC CUBIC PHASE；pH 6.5；293 K；50mM Sodium Cacodylate, 1.6M NaCl, 40% PEG400, pH 6.5, Lipidic Cubic Phase, temperature 293K
分辨率 2.70 Å R-free 0.230
4GP8 Structure of Recombinant Cytochrome ba3 Oxidase mutant Y133W+T231F from Thermus thermophilus 提交 2012-08-20 结构质量不同 Assembly 1 蛋白异源复合物 异源复合物；蛋白 × 3 PDB 声明：trimeric
链 B 1–168（168 aa）
未记录 CU COPPER (II) ION × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 PER PEROXIDE ION × 1 OLC (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate × 16 CUA DINUCLEAR COPPER ION × 1 X-RAY DIFFRACTION
X-ray结晶条件 LIPIDIC CUBIC PHASE；pH 6.5；293 K；50mM Sodium Cacodylate, 1.6M NaCl, 40% PEG400, pH 6.5, Lipidic Cubic Phase, temperature 293K
分辨率 2.80 Å R-free 0.227
4N4Y Structure of Recombinant Cytochrome ba3 Oxidase mutant G232V from Thermus thermophilus 提交 2013-10-08 配体/离子不同 实验环境不同 结构质量不同 Assembly 1 蛋白异源复合物 异源复合物；蛋白 × 3 PDB 声明：trimeric
链 B 1–168（168 aa）
未记录 CU COPPER (II) ION × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 PEO HYDROGEN PEROXIDE × 1 OLC (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate × 16 CUA DINUCLEAR COPPER ION × 1 X-RAY DIFFRACTION
X-ray结晶条件 LIPIDIC CUBIC PHASE；pH 6.5；293 K；50 mM sodium cacodylate, pH 6.5, 1.6 M sodium chloride, 40% PEG400, LIPIDIC CUBIC PHASE, temperature 293K
分辨率 2.90 Å R-free 0.225
5NDC Structure of ba3-type cytochrome c oxidase from Thermus thermophilus by serial femtosecond crystallography 提交 2017-03-08 配体/离子不同 实验环境不同 结构质量不同 Assembly 1 蛋白异源复合物 异源复合物；蛋白 × 3 PDB 声明：trimeric
链 B 1–168（168 aa）
未记录 CU COPPER (II) ION × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 OLC (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate × 15 CUA DINUCLEAR COPPER ION × 1 X-RAY DIFFRACTION
X-ray结晶条件 LIPIDIC CUBIC PHASE；pH 5.3；293 K；100mM sodium cacodylate trihydrate pH 5.3, 37% PEG400, 1.4M NaCl Room temperature for 2-3 days
分辨率 2.30 Å R-free 0.197
8AJZ Serial femtosecond crystallography structure of CO bound ba3- type cytochrome c oxidase at 2 milliseconds after irradiation by a 532 nm laser 提交 2022-07-29 配体/离子不同 实验环境不同 结构质量不同 Assembly 1 蛋白异源复合物 异源复合物；蛋白 × 3 PDB 声明：trimeric
链 B 1–168（168 aa）
未记录 CU COPPER (II) ION × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 OLC (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate × 15 CMO CARBON MONOXIDE × 1 CUA DINUCLEAR COPPER ION × 1 X-RAY DIFFRACTION
X-ray结晶条件 LIPIDIC CUBIC PHASE；pH 5.3；298 K；100 mM 2-Morpholinoethanesulfonic acid, 34-38 % PEG 400 (v/v), 1.4 M NaCl, pH 5.3
分辨率 2.00 Å R-free 0.210
8HUA Serial synchrotron crystallography structure of ba3-type cytochrome c oxidase from Thermus thermophilus using a goniometer compatible flow-cell 提交 2022-12-22 配体/离子不同 实验环境不同 结构质量不同 Assembly 1 蛋白异源复合物 异源复合物；蛋白 × 3 PDB 声明：trimeric
链 B 1–168（168 aa）
未记录 CU COPPER (II) ION × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 OLC (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate × 15 CUA DINUCLEAR COPPER ION × 1 X-RAY DIFFRACTION
X-ray结晶条件 LIPIDIC CUBIC PHASE；pH 5.3；298 K；1.4 M NaCl, 100 mM MES pH 5.3 with 36 % to 39 % (v/v) PEG 400
分辨率 2.12 Å R-free 0.184
8K65 Serial femtosecond crystallography structure of CO bound ba3- type cytochrome c oxidase without pump laser irradiation 提交 2023-07-25 配体/离子不同 实验环境不同 结构质量不同 Assembly 1 蛋白异源复合物 异源复合物；蛋白 × 3 PDB 声明：trimeric
链 B 1–168（168 aa）
未记录 CU COPPER (II) ION × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 OLC (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate × 15 CMO CARBON MONOXIDE × 1 CUA DINUCLEAR COPPER ION × 1 X-RAY DIFFRACTION
X-ray结晶条件 LIPIDIC CUBIC PHASE；pH 5.3；293 K；34-38 % PEG 400 (v/v), 1.4 M NaCl, pH 5.3
分辨率 2.00 Å R-free 0.196
8K6Y Serial femtosecond crystallography structure of photo dissociated CO from ba3- type cytochrome c oxidase determined by extrapolation method 提交 2023-07-25 配体/离子不同 实验环境不同 结构质量不同 Assembly 1 蛋白异源复合物 异源复合物；蛋白 × 3 PDB 声明：trimeric
链 B 1–168（168 aa）
未记录 CU COPPER (II) ION × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 OLC (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate × 15 CMO CARBON MONOXIDE × 1 CUA DINUCLEAR COPPER ION × 1 X-RAY DIFFRACTION
X-ray结晶条件 LIPIDIC CUBIC PHASE；pH 5.3；293 K；34-38 % PEG 400 (v/v), 1.4 M NaCl, pH 5.3
分辨率 2.00 Å R-free 0.435
9GDF Chloride bound structure of oxidized ba3-type cytochrome c oxidase confirmed by single-wavelength anomalous diffraction 提交 2024-08-05 配体/离子不同 实验环境不同 结构质量不同 Assembly 1 蛋白异源复合物 异源复合物；蛋白 × 3 PDB 声明：trimeric
链 B 1–168（168 aa）
未记录 CU COPPER (II) ION × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 OLC (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate × 15 CL CHLORIDE ION × 2 CUA DINUCLEAR COPPER ION × 1 X-RAY DIFFRACTION
X-ray结晶条件 LIPIDIC CUBIC PHASE；pH 5.3；298 K；1.4 M NaCl, 100 mM MES. 40-43 % (v/v) PEG 400
分辨率 2.28 Å R-free 0.197
9VDJ Serial synchrotron crystallography structure of a ba3-type cytochrome c oxidase using a goniometer-compatible chip-based platform 提交 2025-06-08 配体/离子不同 实验环境不同 结构质量不同 Assembly 1 蛋白异源复合物 异源复合物；蛋白 × 3 PDB 声明：trimeric
链 B 1–168（168 aa）
未记录 CU COPPER (II) ION × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 OLC (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate × 15 CUA DINUCLEAR COPPER ION × 1 X-RAY DIFFRACTION
X-ray结晶条件 LIPIDIC CUBIC PHASE；293 K；0.1M MES (pH 5.3), 1.4M NaCl, 39-41% PEG 400
分辨率 2.30 Å R-free 0.264

共 40 个其他 PDB 条目、43 个 assembly。 打开独立比较页并筛选聚集状态

查看构建体与数据证据
UniProt名称 COX2_THET8
Isoform —
PDB实体 2
链与序列区间 作者链 B； PDB构建体 1–168； UniProt 1–168

Cytochrome c oxidase polypeptide 2A

Thermus thermophilus

UniProt P82543

当前结构中的状态

Assembly 聚集状态 构建体 突变与修饰 配体、离子与共同组分 实验方法与环境 结构质量
1 蛋白异源复合物 异源复合物 蛋白 × 3 PDB 声明：trimeric（3） 与蛋白拷贝数一致 链 C； UniProt 1–34 未记录 Cytochrome c oxidase subunit 1 × 1 （Q5SJ79） Cytochrome c oxidase subunit 2 × 1 （Q5SJ80） CU COPPER (II) ION × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 PER PEROXIDE ION × 1 OLC (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate × 16 CUA DINUCLEAR COPPER ION × 1 X-RAY DIFFRACTION X-ray结晶条件：LIPIDIC CUBIC PHASE；pH 6.5；293 K；50mM Sodium Cacodylate, 1.6M NaCl, 40% PEG400, pH 6.5, Lipidic Cubic Phase, temperature 293K 分辨率 2.80 Å R-free 0.227

数据库中的同蛋白其他状态

以下每一行都是同一 UniProt 蛋白在另一个 PDB 条目中的 biological assembly， “相对当前条目”直接指出证据层面的不同；没有差异标签表示当前已读取字段一致。

其他 PDB 相对当前条目 4GP4 Assembly / 聚集状态 构建体 突变与修饰 配体、离子与非聚合物 实验方法与环境 结构质量
1EHK CRYSTAL STRUCTURE OF THE ABERRANT BA3-CYTOCHROME-C OXIDASE FROM THERMUS THERMOPHILUS 提交 2000-02-21 构建体不同 配体/离子不同 实验环境不同 结构质量不同 Assembly 1 蛋白异源复合物 异源复合物；蛋白 × 3 PDB 声明：trimeric
链 C 2–34（33 aa） 片段：SUBUNIT IIA
未记录 BNG nonyl beta-D-glucopyranoside × 3 CU COPPER (II) ION × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 CUA DINUCLEAR COPPER ION × 1 X-RAY DIFFRACTION
X-ray结晶条件 VAPOR DIFFUSION, SITTING DROP；pH 7；293 K；PEG 2000, Bis-Tris buffer, nonyl-beta-D-glucoside, pH 7.0, VAPOR DIFFUSION, SITTING DROP, temperature 293K
分辨率 2.40 Å R-free 0.264
1XME Structure of Recombinant Cytochrome ba3 Oxidase from Thermus thermophilus 提交 2004-10-01 配体/离子不同 实验环境不同 结构质量不同 Assembly 1 蛋白异源复合物 异源复合物；蛋白 × 3 PDB 声明：trimeric
链 C 1–34（34 aa）
未记录 BNG nonyl beta-D-glucopyranoside × 1 CU COPPER (II) ION × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 GOL GLYCEROL × 1 CUA DINUCLEAR COPPER ION × 1 X-RAY DIFFRACTION
X-ray结晶条件 VAPOR DIFFUSION, SITTING DROP；pH 7；297 K；Peg 2000, Bis-tris, pH 7.0, VAPOR DIFFUSION, SITTING DROP, temperature 297K
分辨率 2.30 Å R-free 0.236
2QPD An unexpected outcome of surface-engineering an integral membrane protein: Improved crystallization of cytochrome ba3 oxidase from Thermus thermophilus 提交 2007-07-23 配体/离子不同 实验环境不同 结构质量不同 Assembly 1 蛋白异源复合物 异源复合物；蛋白 × 3 PDB 声明：trimeric
链 C 1–34（34 aa）
未记录 CU1 COPPER (I) ION × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 CUA DINUCLEAR COPPER ION × 1 X-RAY DIFFRACTION
X-ray结晶条件 VAPOR DIFFUSION, SITTING DROP；pH 7；291 K；7% PEK 2K, 50 mM KCl, 20 mM Bis-Tris pH 7.0, 6.5 mM n-nonyl-beta-D-glucopyranoside, VAPOR DIFFUSION, SITTING DROP, temperature 291K
分辨率 3.25 Å R-free 0.307
2QPE An unexpected outcome of surface-engineering an integral membrane protein: Improved crystallization of cytochrome ba3 oxidase from Thermus thermophilus 提交 2007-07-23 配体/离子不同 实验环境不同 结构质量不同 Assembly 1 蛋白异源复合物 异源复合物；蛋白 × 3 PDB 声明：trimeric
链 C 1–34（34 aa）
未记录 CU1 COPPER (I) ION × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 CUA DINUCLEAR COPPER ION × 1 X-RAY DIFFRACTION
X-ray结晶条件 VAPOR DIFFUSION, SITTING DROP；pH 7；291 K；7% PEK 2K, 50 mM KCl, 20 mM Bis-Tris, pH 7.0, 6.5 mM n-nonyl-beta-D-glucopyranoside, VAPOR DIFFUSION, SITTING DROP, temperature 291K
分辨率 2.90 Å R-free 0.302
3BVD Structure of Surface-engineered Cytochrome ba3 Oxidase from Thermus thermophilus under Xenon Pressure, 100psi 5min 提交 2008-01-07 配体/离子不同 实验环境不同 结构质量不同 Assembly 1 蛋白异源复合物 异源复合物；蛋白 × 3 PDB 声明：trimeric
链 C 1–34（34 aa）
未记录 CU COPPER (II) ION × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 XE XENON × 7 CUA DINUCLEAR COPPER ION × 1 X-RAY DIFFRACTION
X-ray结晶条件 VAPOR DIFFUSION；pH 7；297 K；6-9% PEG 2000, 50mM KCl, 7.5-30mM bis-Tris pH 7.0, 6.5mM nonyl-B-D-glucopyranoside , VAPOR DIFFUSION, temperature 297K
分辨率 3.37 Å R-free 0.336
3EH3 Structure of the reduced form of cytochrome ba3 oxidase from Thermus thermophilus 提交 2008-09-11 构建体不同 配体/离子不同 实验环境不同 结构质量不同 Assembly 1 蛋白异源复合物 异源复合物；蛋白 × 3 PDB 声明：trimeric
链 C 2–34（33 aa） 片段：UNP residues 2-34
未记录 CU1 COPPER (I) ION × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 CUA DINUCLEAR COPPER ION × 1 X-RAY DIFFRACTION
X-ray结晶条件 VAPOR DIFFUSION, SITTING DROP；pH 7；297 K；Peg 2000, Bis-tris, pH 7.0, VAPOR DIFFUSION, SITTING DROP, temperature 297K
分辨率 3.10 Å R-free 0.300
3EH3 Structure of the reduced form of cytochrome ba3 oxidase from Thermus thermophilus 提交 2008-09-11 构建体不同 聚集状态不同 配体/离子不同 实验环境不同 结构质量不同 Assembly 4 蛋白单体 单体；蛋白 × 1 PDB 声明：monomeric
链 C 2–34（33 aa） 片段：UNP residues 2-34
未记录 未记录非水小分子 X-RAY DIFFRACTION
X-ray结晶条件 VAPOR DIFFUSION, SITTING DROP；pH 7；297 K；Peg 2000, Bis-tris, pH 7.0, VAPOR DIFFUSION, SITTING DROP, temperature 297K
分辨率 3.10 Å R-free 0.300
3EH4 Structure of the reduced form of cytochrome ba3 oxidase from Thermus thermophilus 提交 2008-09-11 构建体不同 配体/离子不同 实验环境不同 结构质量不同 Assembly 1 蛋白异源复合物 异源复合物；蛋白 × 3 PDB 声明：trimeric
链 C 2–34（33 aa） 片段：UNP residues 2-34
未记录 CU1 COPPER (I) ION × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 CUA DINUCLEAR COPPER ION × 1 BNG nonyl beta-D-glucopyranoside × 1 X-RAY DIFFRACTION
X-ray结晶条件 VAPOR DIFFUSION, SITTING DROP；pH 7；297 K；Peg 2000, Bis-tris, pH 7.0, VAPOR DIFFUSION, SITTING DROP, temperature 297K
分辨率 2.90 Å R-free 0.268
3EH4 Structure of the reduced form of cytochrome ba3 oxidase from Thermus thermophilus 提交 2008-09-11 构建体不同 聚集状态不同 配体/离子不同 实验环境不同 结构质量不同 Assembly 4 蛋白单体 单体；蛋白 × 1 PDB 声明：monomeric
链 C 2–34（33 aa） 片段：UNP residues 2-34
未记录 BNG nonyl beta-D-glucopyranoside × 1 X-RAY DIFFRACTION
X-ray结晶条件 VAPOR DIFFUSION, SITTING DROP；pH 7；297 K；Peg 2000, Bis-tris, pH 7.0, VAPOR DIFFUSION, SITTING DROP, temperature 297K
分辨率 2.90 Å R-free 0.268
3EH5 Structure of the reduced form of cytochrome ba3 oxidase from Thermus thermophilus 提交 2008-09-11 构建体不同 配体/离子不同 实验环境不同 结构质量不同 Assembly 1 蛋白异源复合物 异源复合物；蛋白 × 3 PDB 声明：trimeric
链 C 2–34（33 aa） 片段：UNP residues 2-34
未记录 CU1 COPPER (I) ION × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 BNG nonyl beta-D-glucopyranoside × 4 CUA DINUCLEAR COPPER ION × 1 X-RAY DIFFRACTION
X-ray结晶条件 VAPOR DIFFUSION, SITTING DROP；pH 7；297 K；Peg 2000, Bis-tris, pH 7.0, VAPOR DIFFUSION, SITTING DROP, temperature 297K
分辨率 2.80 Å R-free 0.257
3EH5 Structure of the reduced form of cytochrome ba3 oxidase from Thermus thermophilus 提交 2008-09-11 构建体不同 聚集状态不同 配体/离子不同 实验环境不同 结构质量不同 Assembly 4 蛋白单体 单体；蛋白 × 1 PDB 声明：monomeric
链 C 2–34（33 aa） 片段：UNP residues 2-34
未记录 BNG nonyl beta-D-glucopyranoside × 1 X-RAY DIFFRACTION
X-ray结晶条件 VAPOR DIFFUSION, SITTING DROP；pH 7；297 K；Peg 2000, Bis-tris, pH 7.0, VAPOR DIFFUSION, SITTING DROP, temperature 297K
分辨率 2.80 Å R-free 0.257
3QJQ The structure of and photolytic induced changes of carbon monoxide binding to the cytochrome ba3-oxidase from Thermus thermophilus 提交 2011-01-30 配体/离子不同 实验环境不同 结构质量不同 Assembly 1 蛋白异源复合物 异源复合物；蛋白 × 3 PDB 声明：trimeric
链 C 1–34（34 aa）
未记录 CU1 COPPER (I) ION × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 CMO CARBON MONOXIDE × 1 CUA DINUCLEAR COPPER ION × 1 X-RAY DIFFRACTION
X-ray结晶条件 VAPOR DIFFUSION, SITTING DROP；pH 7；297 K；7% PEK 2K, 50 mM KCl, 20 mM Bis-Tris pH 7.0, 6.5 mM n-nonyl-beta-D glucopyranoside, VAPOR DIFFUSION, SITTING DROP, temperature 297K
分辨率 2.90 Å R-free 0.284
3QJR The structure of and photolytic induced changes of carbon monoxide binding to the cytochrome ba3-oxidase from Thermus thermophilus 提交 2011-01-30 配体/离子不同 实验环境不同 结构质量不同 Assembly 1 蛋白异源复合物 异源复合物；蛋白 × 3 PDB 声明：trimeric
链 C 1–34（34 aa）
未记录 CU1 COPPER (I) ION × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 CMO CARBON MONOXIDE × 1 CUA DINUCLEAR COPPER ION × 1 X-RAY DIFFRACTION
X-ray结晶条件 VAPOR DIFFUSION, SITTING DROP；pH 7；297 K；7% PEK 2K, 50 mM KCl, 20 mM Bis-Tris pH 7.0, 6.5 mM n-nonyl-beta-D-glucopyranoside , VAPOR DIFFUSION, SITTING DROP, temperature 297K
分辨率 3.20 Å R-free 0.367
3QJS The structure of and photolytic induced changes of carbon monoxide binding to the cytochrome ba3-oxidase from Thermus thermophilus 提交 2011-01-30 配体/离子不同 实验环境不同 结构质量不同 Assembly 1 蛋白异源复合物 异源复合物；蛋白 × 3 PDB 声明：trimeric
链 C 1–34（34 aa）
未记录 CU1 COPPER (I) ION × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 CMO CARBON MONOXIDE × 1 CUA DINUCLEAR COPPER ION × 1 X-RAY DIFFRACTION
X-ray结晶条件 VAPOR DIFFUSION, SITTING DROP；pH 7；297 K；7% PEK 2K, 50 mM KCl, 20 mM Bis-Tris pH 7.0, 6.5 mM n-nonyl-beta-D-glucopyranoside , VAPOR DIFFUSION, SITTING DROP, temperature 297K
分辨率 2.80 Å R-free 0.265
3QJT The structure of and photolytic induced changes of carbon monoxide binding to the cytochrome ba3-oxidase from Thermus thermophilus 提交 2011-01-30 配体/离子不同 实验环境不同 结构质量不同 Assembly 1 蛋白异源复合物 异源复合物；蛋白 × 3 PDB 声明：trimeric
链 C 1–34（34 aa）
未记录 CU1 COPPER (I) ION × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 CMO CARBON MONOXIDE × 1 CUA DINUCLEAR COPPER ION × 1 X-RAY DIFFRACTION
X-ray结晶条件 VAPOR DIFFUSION, SITTING DROP；pH 7；297 K；7% PEK 2K, 50 mM KCl, 20 mM Bis-Tris pH 7.0, 6.5 mM n-nonyl-beta-D-glucopyranoside , VAPOR DIFFUSION, SITTING DROP, temperature 297K
分辨率 2.95 Å R-free 0.323
3QJU The structure of and photolytic induced changes of carbon monoxide binding to the cytochrome ba3-oxidase from Thermus thermophilus 提交 2011-01-30 配体/离子不同 实验环境不同 结构质量不同 Assembly 1 蛋白异源复合物 异源复合物；蛋白 × 3 PDB 声明：trimeric
链 C 1–34（34 aa）
未记录 CU1 COPPER (I) ION × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 CMO CARBON MONOXIDE × 1 CUA DINUCLEAR COPPER ION × 1 X-RAY DIFFRACTION
X-ray结晶条件 VAPOR DIFFUSION, SITTING DROP；pH 7；297 K；7% PEK 2K, 50 mM KCl, 20 mM Bis-Tris pH 7.0, 6.5 mM n-nonyl-beta-D-glucopyranoside, VAPOR DIFFUSION, SITTING DROP, temperature 297K
分辨率 2.90 Å R-free 0.329
3QJV The structure of and photolytic induced changes of carbon monoxide binding to the cytochrome ba3-oxidase from Thermus thermophilus 提交 2011-01-30 配体/离子不同 实验环境不同 结构质量不同 Assembly 1 蛋白异源复合物 异源复合物；蛋白 × 3 PDB 声明：trimeric
链 C 1–34（34 aa）
未记录 CU1 COPPER (I) ION × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 CMO CARBON MONOXIDE × 1 CUA DINUCLEAR COPPER ION × 1 X-RAY DIFFRACTION
X-ray结晶条件 VAPOR DIFFUSION, SITTING DROP；pH 7；297 K；7% PEK 2K, 50 mM KCl, 20 mM Bis-Tris pH 7.0, 6.5 mM n-nonyl-beta-D-glucopyranoside, VAPOR DIFFUSION, SITTING DROP, temperature 297K
分辨率 2.80 Å R-free 0.274
3S33 Structure of Thermus thermophilus cytochrome ba3 oxidase 10s after Xe depressurization 提交 2011-05-17 构建体不同 配体/离子不同 实验环境不同 结构质量不同 Assembly 1 蛋白异源复合物 异源复合物；蛋白 × 3 PDB 声明：trimeric
链 C 2–34（33 aa）
未记录 CU COPPER (II) ION × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 XE XENON × 5 CUA DINUCLEAR COPPER ION × 1 X-RAY DIFFRACTION
X-ray结晶条件 VAPOR DIFFUSION, HANGING DROP；pH 7；297 K；12-17% PEG 2000, 0-200mM KCl, 15-60mM bis-Tris pH 7.0, 6.5mM nonyl-B-D-glucopyranoside, vapor diffusion, hanging drop, temperature 297K
分辨率 4.45 Å R-free 0.350
3S38 Structure of Thermus thermophilus cytochrome ba3 oxidase 30s after Xe depressurization 提交 2011-05-17 构建体不同 配体/离子不同 实验环境不同 结构质量不同 Assembly 1 蛋白异源复合物 异源复合物；蛋白 × 3 PDB 声明：trimeric
链 C 2–34（33 aa）
未记录 CU COPPER (II) ION × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 XE XENON × 4 CUA DINUCLEAR COPPER ION × 1 X-RAY DIFFRACTION
X-ray结晶条件 VAPOR DIFFUSION, HANGING DROP；pH 7；297 K；12-17% PEG 2000, 0-200mM KCl, 15-60mM bis-Tris pH 7.0, 6.5mM nonyl-B-D-glucopyranoside, vapor diffusion, hanging drop, temperature 297K
分辨率 4.20 Å R-free 0.325
3S39 Structure of Thermus thermophilus cytochrome ba3 oxidase 60s after Xe depressurization 提交 2011-05-17 构建体不同 配体/离子不同 实验环境不同 结构质量不同 Assembly 1 蛋白异源复合物 异源复合物；蛋白 × 3 PDB 声明：trimeric
链 C 2–34（33 aa）
未记录 CU COPPER (II) ION × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 XE XENON × 4 CUA DINUCLEAR COPPER ION × 1 X-RAY DIFFRACTION
X-ray结晶条件 VAPOR DIFFUSION, HANGING DROP；pH 7；297 K；12-17% PEG 2000, 0-200mM KCl, 15-60mM bis-Tris pH 7.0, 6.5mM nonyl-B-D-glucopyranoside, vapor diffusion, hanging drop, temperature 297K
分辨率 4.80 Å R-free 0.341
3S3A Structure of Thermus thermophilus cytochrome ba3 oxidase 120s after Xe depressurization 提交 2011-05-18 构建体不同 配体/离子不同 实验环境不同 结构质量不同 Assembly 1 蛋白异源复合物 异源复合物；蛋白 × 3 PDB 声明：trimeric
链 C 2–34（33 aa）
未记录 CU COPPER (II) ION × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 XE XENON × 4 CUA DINUCLEAR COPPER ION × 1 X-RAY DIFFRACTION
X-ray结晶条件 VAPOR DIFFUSION, HANGING DROP；pH 7；297 K；12-17% PEG 2000, 0-200mM KCl, 15-60mM bis-Tris pH 7.0, 6.5mM nonyl-B-D-glucopyranoside, vapor diffusion, hanging drop, temperature 297K
分辨率 4.25 Å R-free 0.330
3S3B Structure of Thermus thermophilus cytochrome ba3 oxidase 240s after Xe depressurization 提交 2011-05-18 构建体不同 配体/离子不同 实验环境不同 结构质量不同 Assembly 1 蛋白异源复合物 异源复合物；蛋白 × 3 PDB 声明：trimeric
链 C 2–34（33 aa）
未记录 CU COPPER (II) ION × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 XE XENON × 3 CUA DINUCLEAR COPPER ION × 1 X-RAY DIFFRACTION
X-ray结晶条件 VAPOR DIFFUSION, HANGING DROP；pH 7；297 K；12-17% PEG 2000, 0-200mM KCl, 15-60mM bis-Tris pH 7.0, 6.5mM nonyl-B-D-glucopyranoside, vapor diffusion, hanging drop, temperature 297K
分辨率 3.30 Å R-free 0.299
3S3C Structure of Thermus thermophilus cytochrome ba3 oxidase 360s after Xe depressurization 提交 2011-05-18 构建体不同 配体/离子不同 实验环境不同 结构质量不同 Assembly 1 蛋白异源复合物 异源复合物；蛋白 × 3 PDB 声明：trimeric
链 C 2–34（33 aa）
未记录 CU COPPER (II) ION × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 XE XENON × 3 CUA DINUCLEAR COPPER ION × 1 X-RAY DIFFRACTION
X-ray结晶条件 pH 7；297 K；12-17% PEG 2000, 0-200mM KCl, 15-60mM bis-Tris pH 7.0, 6.5mM nonyl-B-D-glucopyranoside, vapor diffusion, hanging drop, temperature 297K
分辨率 4.00 Å R-free 0.373
3S3D Structure of Thermus thermophilus cytochrome ba3 oxidase 480s after Xe depressurization 提交 2011-05-18 构建体不同 配体/离子不同 实验环境不同 结构质量不同 Assembly 1 蛋白异源复合物 异源复合物；蛋白 × 3 PDB 声明：trimeric
链 C 2–34（33 aa）
未记录 CU COPPER (II) ION × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 XE XENON × 3 CUA DINUCLEAR COPPER ION × 1 X-RAY DIFFRACTION
X-ray结晶条件 pH 7；297 K；12-17% PEG 2000, 0-200mM KCl, 15-60mM bis-Tris pH 7.0, 6.5mM nonyl-B-D-glucopyranoside, vapor diffusion, hanging drop, temperature 297K
分辨率 3.75 Å R-free 0.293
3S8F 1.8 A structure of ba3 cytochrome c oxidase from Thermus thermophilus in lipid environment 提交 2011-05-27 实验环境不同 结构质量不同 Assembly 1 蛋白异源复合物 异源复合物；蛋白 × 3 PDB 声明：trimeric
链 C 1–34（34 aa）
未记录 CU COPPER (II) ION × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 PER PEROXIDE ION × 1 OLC (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate × 16 CUA DINUCLEAR COPPER ION × 1 X-RAY DIFFRACTION
X-ray结晶条件 LIPIDIC CUBIC PHASE；pH 6；293 K；40-45% PEG 400, 1.0-1.6M NaCl, 100mM sodium cacodylate trihydrate pH 5.5-6.5, lipidic cubic phase with monolein, temperature 293K
分辨率 1.80 Å R-free 0.215
3S8G 1.8 A structure of ba3 cytochrome c oxidase mutant (A120F) from Thermus thermophilus in lipid environment 提交 2011-05-27 配体/离子不同 实验环境不同 结构质量不同 Assembly 1 蛋白异源复合物 异源复合物；蛋白 × 3 PDB 声明：trimeric
链 C 1–34（34 aa）
未记录 HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 CU COPPER (II) ION × 1 PER PEROXIDE ION × 1 OLC (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate × 20 CUA DINUCLEAR COPPER ION × 1 X-RAY DIFFRACTION
X-ray结晶条件 LIPIDIC CUBIC PHASE；293 K；40-45% PEG 400, 1.0-1.6M NaCl, 100mM sodium cacodylate trihydrate pH 5.5-6.5, lipidic cubic phase with monolein, temperature 293K
分辨率 1.80 Å R-free 0.196
4FA7 Structure of Recombinant Cytochrome ba3 Oxidase mutant A204F from Thermus thermophilus 提交 2012-05-21 配体/离子不同 结构质量不同 Assembly 1 蛋白异源复合物 异源复合物；蛋白 × 3 PDB 声明：trimeric
链 C 1–34（34 aa）
未记录 CU COPPER (II) ION × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 PEO HYDROGEN PEROXIDE × 1 OLC (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate × 16 CUA DINUCLEAR COPPER ION × 1 X-RAY DIFFRACTION
X-ray结晶条件 LIPIDIC CUBIC PHASE；pH 6.5；293 K；50mM Sodium Cacodylate, 1.6M NaCl, 40% PEG400, pH 6.5, Lipidic Cubic Phase, temperature 293K
分辨率 2.50 Å R-free 0.220
4FAA Structure of Recombinant Cytochrome ba3 Oxidase mutant A120F+A204F from Thermus thermophilus 提交 2012-05-21 配体/离子不同 结构质量不同 Assembly 1 蛋白异源复合物 异源复合物；蛋白 × 3 PDB 声明：trimeric
链 C 1–34（34 aa）
未记录 CU COPPER (II) ION × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 PEO HYDROGEN PEROXIDE × 1 OLC (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate × 16 CUA DINUCLEAR COPPER ION × 1 X-RAY DIFFRACTION
X-ray结晶条件 LIPIDIC CUBIC PHASE；pH 6.5；293 K；50mM Sodium Cacodylate, 1.6M NaCl, 40% PEG400, pH 6.5, Lipidic Cubic Phase, temperature 293K
分辨率 2.80 Å R-free 0.254
4G70 Structure of Recombinant Cytochrome ba3 Oxidase mutant V236T from Thermus thermophilus 提交 2012-07-19 实验环境不同 结构质量不同 Assembly 1 蛋白异源复合物 异源复合物；蛋白 × 3 PDB 声明：trimeric
链 C 1–34（34 aa）
未记录 HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 CU COPPER (II) ION × 1 PER PEROXIDE ION × 1 OLC (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate × 16 CUA DINUCLEAR COPPER ION × 1 X-RAY DIFFRACTION
X-ray结晶条件 LIPIDIC CUBIC PHASE；pH 6.5；293 K；50mM Sodium Cacodylate PH 6.5, 1.6M NaCl, 40% PEG400 , Lipidic Cubic Phase, temperature 293K
分辨率 2.60 Å R-free 0.252
4G71 Structure of Recombinant Cytochrome ba3 Oxidase mutant V236N from Thermus thermophilus 提交 2012-07-19 配体/离子不同 实验环境不同 结构质量不同 Assembly 1 蛋白异源复合物 异源复合物；蛋白 × 3 PDB 声明：trimeric
链 C 1–34（34 aa）
未记录 CUB CU(I)-S-MO(IV)(=O)O-NBIC CLUSTER × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 PER PEROXIDE ION × 1 OLC (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate × 16 CUA DINUCLEAR COPPER ION × 1 X-RAY DIFFRACTION
X-ray结晶条件 LIPIDIC CUBIC PHASE；pH 6.5；293 K；50mM Sodium Cacodylate PH 6.5, 1.6M NaCl, 40% PEG400 , Lipidic Cubic Phase, temperature 293K
分辨率 2.90 Å R-free 0.224
4G72 Structure of Recombinant Cytochrome ba3 Oxidase mutant V236M from Thermus thermophilus 提交 2012-07-19 实验环境不同 结构质量不同 Assembly 1 蛋白异源复合物 异源复合物；蛋白 × 3 PDB 声明：trimeric
链 C 1–34（34 aa）
未记录 CU COPPER (II) ION × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 PER PEROXIDE ION × 1 OLC (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate × 16 CUA DINUCLEAR COPPER ION × 1 X-RAY DIFFRACTION
X-ray结晶条件 LIPIDIC CUBIC PHASE；pH 6.5；293 K；50mM Sodium Cacodylate PH 6.5, 1.6M NaCl, 40% PEG400 , Lipidic Cubic Phase, temperature 293K
分辨率 3.19 Å R-free 0.223
4G7Q Structure of Recombinant Cytochrome ba3 Oxidase mutant V236L from Thermus thermophilus 提交 2012-07-20 实验环境不同 结构质量不同 Assembly 1 蛋白异源复合物 异源复合物；蛋白 × 3 PDB 声明：trimeric
链 C 1–34（34 aa）
未记录 CU COPPER (II) ION × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 PER PEROXIDE ION × 1 OLC (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate × 16 CUA DINUCLEAR COPPER ION × 1 X-RAY DIFFRACTION
X-ray结晶条件 LIPIDIC CUBIC PHASE；pH 6.5；293 K；50mM Sodium Cacodylate PH 6.5, 1.6M NaCl, 40% PEG400 , Lipidic Cubic Phase, temperature 293K
分辨率 2.60 Å R-free 0.232
4G7R Structure of Recombinant Cytochrome ba3 Oxidase mutant V236A from Thermus thermophilus 提交 2012-07-20 配体/离子不同 实验环境不同 结构质量不同 Assembly 1 蛋白异源复合物 异源复合物；蛋白 × 3 PDB 声明：trimeric
链 C 1–34（34 aa）
未记录 CU COPPER (II) ION × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 PER PEROXIDE ION × 1 OLC (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate × 15 CUA DINUCLEAR COPPER ION × 1 X-RAY DIFFRACTION mmCIF 未提供已读取条件 分辨率 3.05 Å R-free 0.231
4G7S Structure of Recombinant Cytochrome ba3 Oxidase mutant V236I from Thermus thermophilus 提交 2012-07-20 配体/离子不同 实验环境不同 结构质量不同 Assembly 1 蛋白异源复合物 异源复合物；蛋白 × 3 PDB 声明：trimeric
链 C 1–34（34 aa）
未记录 CU COPPER (II) ION × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 PER PEROXIDE ION × 1 OLC (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate × 15 CUA DINUCLEAR COPPER ION × 1 X-RAY DIFFRACTION
X-ray结晶条件 LIPIDIC CUBIC PHASE；pH 6.5；293 K；50mM Sodium Cacodylate PH 6.5, 1.6M NaCl, 40% PEG400 , Lipidic Cubic Phase, temperature 293K
分辨率 2.00 Å R-free 0.207
4GP5 Structure of Recombinant Cytochrome ba3 Oxidase mutant Y133W from Thermus thermophilus 提交 2012-08-20 结构质量不同 Assembly 1 蛋白异源复合物 异源复合物；蛋白 × 3 PDB 声明：trimeric
链 C 1–34（34 aa）
未记录 CU COPPER (II) ION × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 PER PEROXIDE ION × 1 OLC (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate × 16 CUA DINUCLEAR COPPER ION × 1 X-RAY DIFFRACTION
X-ray结晶条件 LIPIDIC CUBIC PHASE；pH 6.5；293 K；50mM Sodium Cacodylate, 1.6M NaCl, 40% PEG400, pH 6.5, Lipidic Cubic Phase, temperature 293K
分辨率 2.70 Å R-free 0.230
4GP8 Structure of Recombinant Cytochrome ba3 Oxidase mutant Y133W+T231F from Thermus thermophilus 提交 2012-08-20 结构质量不同 Assembly 1 蛋白异源复合物 异源复合物；蛋白 × 3 PDB 声明：trimeric
链 C 1–34（34 aa）
未记录 CU COPPER (II) ION × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 PER PEROXIDE ION × 1 OLC (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate × 16 CUA DINUCLEAR COPPER ION × 1 X-RAY DIFFRACTION
X-ray结晶条件 LIPIDIC CUBIC PHASE；pH 6.5；293 K；50mM Sodium Cacodylate, 1.6M NaCl, 40% PEG400, pH 6.5, Lipidic Cubic Phase, temperature 293K
分辨率 2.80 Å R-free 0.227
4N4Y Structure of Recombinant Cytochrome ba3 Oxidase mutant G232V from Thermus thermophilus 提交 2013-10-08 配体/离子不同 实验环境不同 结构质量不同 Assembly 1 蛋白异源复合物 异源复合物；蛋白 × 3 PDB 声明：trimeric
链 C 1–34（34 aa）
未记录 CU COPPER (II) ION × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 PEO HYDROGEN PEROXIDE × 1 OLC (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate × 16 CUA DINUCLEAR COPPER ION × 1 X-RAY DIFFRACTION
X-ray结晶条件 LIPIDIC CUBIC PHASE；pH 6.5；293 K；50 mM sodium cacodylate, pH 6.5, 1.6 M sodium chloride, 40% PEG400, LIPIDIC CUBIC PHASE, temperature 293K
分辨率 2.90 Å R-free 0.225
8HUA Serial synchrotron crystallography structure of ba3-type cytochrome c oxidase from Thermus thermophilus using a goniometer compatible flow-cell 提交 2022-12-22 配体/离子不同 实验环境不同 结构质量不同 Assembly 1 蛋白异源复合物 异源复合物；蛋白 × 3 PDB 声明：trimeric
链 C 1–34（34 aa）
未记录 CU COPPER (II) ION × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 OLC (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate × 15 CUA DINUCLEAR COPPER ION × 1 X-RAY DIFFRACTION
X-ray结晶条件 LIPIDIC CUBIC PHASE；pH 5.3；298 K；1.4 M NaCl, 100 mM MES pH 5.3 with 36 % to 39 % (v/v) PEG 400
分辨率 2.12 Å R-free 0.184
8K65 Serial femtosecond crystallography structure of CO bound ba3- type cytochrome c oxidase without pump laser irradiation 提交 2023-07-25 配体/离子不同 实验环境不同 结构质量不同 Assembly 1 蛋白异源复合物 异源复合物；蛋白 × 3 PDB 声明：trimeric
链 C 1–34（34 aa）
未记录 CU COPPER (II) ION × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 OLC (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate × 15 CMO CARBON MONOXIDE × 1 CUA DINUCLEAR COPPER ION × 1 X-RAY DIFFRACTION
X-ray结晶条件 LIPIDIC CUBIC PHASE；pH 5.3；293 K；34-38 % PEG 400 (v/v), 1.4 M NaCl, pH 5.3
分辨率 2.00 Å R-free 0.196
8K6Y Serial femtosecond crystallography structure of photo dissociated CO from ba3- type cytochrome c oxidase determined by extrapolation method 提交 2023-07-25 配体/离子不同 实验环境不同 结构质量不同 Assembly 1 蛋白异源复合物 异源复合物；蛋白 × 3 PDB 声明：trimeric
链 C 1–34（34 aa）
未记录 CU COPPER (II) ION × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 OLC (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate × 15 CMO CARBON MONOXIDE × 1 CUA DINUCLEAR COPPER ION × 1 X-RAY DIFFRACTION
X-ray结晶条件 LIPIDIC CUBIC PHASE；pH 5.3；293 K；34-38 % PEG 400 (v/v), 1.4 M NaCl, pH 5.3
分辨率 2.00 Å R-free 0.435
9GDF Chloride bound structure of oxidized ba3-type cytochrome c oxidase confirmed by single-wavelength anomalous diffraction 提交 2024-08-05 配体/离子不同 实验环境不同 结构质量不同 Assembly 1 蛋白异源复合物 异源复合物；蛋白 × 3 PDB 声明：trimeric
链 C 1–34（34 aa）
未记录 CU COPPER (II) ION × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 OLC (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate × 15 CL CHLORIDE ION × 2 CUA DINUCLEAR COPPER ION × 1 X-RAY DIFFRACTION
X-ray结晶条件 LIPIDIC CUBIC PHASE；pH 5.3；298 K；1.4 M NaCl, 100 mM MES. 40-43 % (v/v) PEG 400
分辨率 2.28 Å R-free 0.197
9VDJ Serial synchrotron crystallography structure of a ba3-type cytochrome c oxidase using a goniometer-compatible chip-based platform 提交 2025-06-08 配体/离子不同 实验环境不同 结构质量不同 Assembly 1 蛋白异源复合物 异源复合物；蛋白 × 3 PDB 声明：trimeric
链 C 1–34（34 aa）
未记录 CU COPPER (II) ION × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 OLC (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate × 15 CUA DINUCLEAR COPPER ION × 1 X-RAY DIFFRACTION
X-ray结晶条件 LIPIDIC CUBIC PHASE；293 K；0.1M MES (pH 5.3), 1.4M NaCl, 39-41% PEG 400
分辨率 2.30 Å R-free 0.264

共 39 个其他 PDB 条目、42 个 assembly。 打开独立比较页并筛选聚集状态

查看构建体与数据证据
UniProt名称 COXA_THET8
Isoform —
PDB实体 3
链与序列区间 作者链 C； PDB构建体 1–34； UniProt 1–34

页面优先展示蛋白身份、当前 assembly、共同组分、聚集状态和跨 PDB 结构链接。 链映射与序列区间收在“数据证据”中；数据库内部编号、导入时间和 assembly 操作表达式仅用于维护，因此不在读者页面展示。

SAXS 散射曲线 SAXS Profile

SAXS profile for 4gp4

P(r) 距离分布 P(r) Distribution

P(r) distribution for 4gp4
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2. 结构基本信息 2. Structure Basics

条目编号 entry_id4gp4
沉积日期 deposition_date2012-08-20
结构标题 titleStructure of Recombinant Cytochrome ba3 Oxidase mutant Y133F from Thermus thermophilus
关键词 keywordsOXIDOREDUCTASE, Proton Pump; OXIDOREDUCTASE
实验方法 methodX-RAY DIFFRACTION
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3. SAXS 参数 (CRYSOL 理论计算) 3. SAXS Parameters (CRYSOL)

回转半径 Rg (Guinier) rg_guinier27.11 Å
回转半径 Rg (电子) rg_electron25.79 Å
零角强度 I(0) i091109700.00
分子量 molecular_weight89527.0 kDa
排除体积 excluded_volume117860 ų
包络体积 envelope_volume128270 ų
水化壳体积 shell_volume39220 ų
包络直径 envelope_diameter89.6 Å
壳层 Rg shell_rg35.01 Å
包络 Rg envelope_rg26.28 Å
形状 Rg shape_rg25.77 Å
总 Rg total_rg26.89 Å
总原子数 total_atoms6343
残基数 n_residues751
球谐函数阶数 n_harmonics20
q 范围 q_range— – 0.5000 Å−1
数据点数 n_points101
壳层类型 shell_typedirectional
溶剂电子密度 solvent_density0.3340 e/ų
壳层衬度 contrast_shell0.0300 e/ų
CRYSOL 版本 crysol_version4.1.3
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4. P(r) 距离分布 (GNOM 反演) 4. P(r) Analysis (GNOM)

最大尺寸 Dmax dmax89.5 Å
Rg (实空间) rg_real27.03 Å
Rg 误差 (实空间) rg_real_error0.63 Å
I(0) (实空间) i0_real9.1110e+07
I(0) 误差 (实空间) i0_real_error1.3140e+06
Rg (倒空间) rg_reciprocal27.06 Å
I(0) (倒空间) i0_reciprocal91110000.0000
解质量估计 total_estimate0.8825
解质量评级 solution_quality GOOD a GOOD solution
P(r) 峰数 n_peaks2
主峰位置 r_peak_primary31.9 Å
偏度 Skewness skewness0.312
峰度 Kurtosis kurtosis-0.317
角度范围 angular_range— – 0.2950 Å−1
当前正则化参数 α current_alpha0.0000
最高正则化参数 α highest_alpha24500000.0000
实空间数据点数 n_real_points60
GNOM 版本 gnom_version4.1.3
质量判据 quality_criteria AN1: 0.000; Oscil: 0.835; Stabil: 1.000; Sysdev: 1.000; Positv: 1.000; Valcen: 0.996; Smooth: 0.967
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5. 晶体学与实验 5. Crystallography & Experiment

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6. 实体与聚合物信息 Entities & Polymers (10)

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7. 折叠分类 (SCOP + CATH) 7 domains

SCOP 2.08 (4 domains)

结构域编号 domain_idd4gp4a_
类 Class classf — Membrane and cell surface proteins and peptides
折叠类型 Fold foldf.24 — Cytochrome c oxidase subunit I-like
超家族 Superfamily superfamilyf.24.1 — Cytochrome c oxidase subunit I-like
家族 Family familyf.24.1.1 — Cytochrome c oxidase subunit I-like
结构域编号 domain_idd4gp4b1
类 Class classf — Membrane and cell surface proteins and peptides
折叠类型 Fold foldf.17 — Transmembrane helix hairpin
超家族 Superfamily superfamilyf.17.2 — Cytochrome c oxidase subunit II-like, transmembrane region
家族 Family familyf.17.2.1 — Cytochrome c oxidase subunit II-like, transmembrane region
结构域编号 domain_idd4gp4b2
类 Class classb — All beta proteins
折叠类型 Fold foldb.6 — Cupredoxin-like
超家族 Superfamily superfamilyb.6.1 — Cupredoxins
家族 Family familyb.6.1.2 — Periplasmic domain of cytochrome c oxidase subunit II
结构域编号 domain_idd4gp4c_
类 Class classf — Membrane and cell surface proteins and peptides
折叠类型 Fold foldf.23 — Single transmembrane helix
超家族 Superfamily superfamilyf.23.9 — Bacterial ba3 type cytochrome c oxidase subunit IIa
家族 Family familyf.23.9.1 — Bacterial ba3 type cytochrome c oxidase subunit IIa

CATH v4.4 (3 domains)

结构域编号 domain_id4gp4A00
类 Class class1 — Mainly Alpha
架构 Architecture architecture20 — Up-down Bundle
拓扑 Topology topology210 — Cytochrome C Oxidase; Chain A
同源超家族 H-superfamily homologous superfamily10 — Cytochrome c oxidase-like, subunit I domain
结构域编号 domain_id4gp4B01
类 Class class1 — Mainly Alpha
架构 Architecture architecture20 — Up-down Bundle
拓扑 Topology topology1070 — Rhopdopsin 7-helix transmembrane proteins
同源超家族 H-superfamily homologous superfamily10 — Rhodopsin 7-helix transmembrane proteins
结构域编号 domain_id4gp4B02
类 Class class2 — Mainly Beta
架构 Architecture architecture60 — Sandwich
拓扑 Topology topology40 — Immunoglobulin-like
同源超家族 H-superfamily homologous superfamily420 — Cupredoxins - blue copper proteins
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8. 引用文献 (1)

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9. 文件与曲线 (10)