Mus musculus
| Assembly | Physical composition | Protein state | Molecular copy count | Associated components | Data consistency |
|---|---|---|---|---|---|
| 1 | Protein homooligomer | Homooligomer | Protein 2 | GOLD ION × 4 | Consistent with protein count |
| UniProt name | BTK_MOUSE |
| Isoform | — |
| PDB entities | 1 |
| Chains and sequence ranges | Author chain A； PDBConstruct 1–446； UniProt 214–659 |
The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.
| Entry ID entry_id | 4xi2 |
| Deposition date deposition_date | 2015-01-06 |
| Structure title title | Crystal Structure of an auto-inhibited form of Bruton's Tryrosine Kinase |
| Keywords keywords | Kinase, Phosphorylation, Auto-inhibited, B-Cell development, X-linked agammaglobulinemia, TRANSFERASE; TRANSFERASE |
| Experimental Method method | X-RAY DIFFRACTION |
This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.
Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)
| Rg（Guinier） | 45.27 Å |
| Rg (electron density) | 45.28 Å |
| Total Rg | 45.72 Å |
| Atom count | 13670 |
| Residues | 842 |
| Excluded volume | 123460 ų |
| Maximum q | 0.500 Å⁻¹ |
| Domain ID domain_id | d4xi2a1 |
| Class class | b — All beta proteins |
| Fold Fold fold | b.34 — SH3-like barrel |
| Superfamily Superfamily superfamily | b.34.2 — SH3-domain |
| Family Family family | b.34.2.0 — automated matches |
| Domain ID domain_id | d4xi2a2 |
| Class class | d — Alpha and beta proteins (a+b) |
| Fold Fold fold | d.144 — Protein kinase-like (PK-like) |
| Superfamily Superfamily superfamily | d.144.1 — Protein kinase-like (PK-like) |
| Family Family family | d.144.1.0 — automated matches |
| Domain ID domain_id | 4xi2A01 |
| Class class | 2 — Mainly Beta |
| Architecture architecture | 30 — Roll |
| Topology topology | 30 — SH3 type barrels. |
| Homologous superfamily homologous superfamily | 40 — SH3 Domains |
| Domain ID domain_id | 4xi2A02 |
| Class class | 3 — Alpha Beta |
| Architecture architecture | 30 — 2-Layer Sandwich |
| Topology topology | 200 — Phosphorylase Kinase; domain 1 |
| Homologous superfamily homologous superfamily | 20 — Phosphorylase Kinase; domain 1 |
| Domain ID domain_id | 4xi2A03 |
| Class class | 1 — Mainly Alpha |
| Architecture architecture | 10 — Orthogonal Bundle |
| Topology topology | 510 — Transferase(Phosphotransferase); domain 1 |
| Homologous superfamily homologous superfamily | 10 — Transferase(Phosphotransferase) domain 1 |