Homo sapiens
| Assembly | Physical composition | Protein state | Molecular copy count | Associated components | Data consistency |
|---|---|---|---|---|---|
| 1 | Protein monomer | Monomer | Protein 1 | Nilotinib × 1 asciminib × 1 water × 1 | Consistent with protein count |
| UniProt name | ABL1_HUMAN |
| Isoform | — |
| PDB entities | 1 |
| Chains and sequence ranges | Author chain A； PDBConstruct 7–495； UniProt 27–515 |
The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.
| Entry ID entry_id | 5mo4 |
| Deposition date deposition_date | 2016-12-13 |
| Structure title title | ABL1 kinase (T334I_D382N) in complex with asciminib and nilotinib |
| Keywords keywords | Kinase, drug, inhibitor, transferase; TRANSFERASE |
| Experimental Method method | X-RAY DIFFRACTION |
This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.
Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)
| Rg（Guinier） | 24.69 Å |
| Rg (electron density) | 23.64 Å |
| Total Rg | 24.46 Å |
| Atom count | 3455 |
| Residues | 429 |
| Excluded volume | 61203 ų |
| Maximum q | 0.500 Å⁻¹ |
| Domain ID domain_id | d5mo4a1 |
| Class class | b — All beta proteins |
| Fold Fold fold | b.34 — SH3-like barrel |
| Superfamily Superfamily superfamily | b.34.2 — SH3-domain |
| Family Family family | b.34.2.1 — SH3-domain |
| Domain ID domain_id | d5mo4a2 |
| Class class | d — Alpha and beta proteins (a+b) |
| Fold Fold fold | d.93 — SH2-like |
| Superfamily Superfamily superfamily | d.93.1 — SH2 domain |
| Family Family family | d.93.1.0 — automated matches |
| Domain ID domain_id | d5mo4a3 |
| Class class | d — Alpha and beta proteins (a+b) |
| Fold Fold fold | d.144 — Protein kinase-like (PK-like) |
| Superfamily Superfamily superfamily | d.144.1 — Protein kinase-like (PK-like) |
| Family Family family | d.144.1.7 — Protein kinases, catalytic subunit |