Mus musculus
| Assembly | 物理组成 | 蛋白状态 | 分子拷贝数 | 共同组分 | 数据核对 |
|---|---|---|---|---|---|
| 1 | 蛋白–DNA | 同源多聚体 | 蛋白 6 DNA 8 | DNA (37-MER) × 4 DNA (36-MER) × 4 ZINC ION × 6 | 与全部聚合物一致 |
| UniProt名称 | CGAS_MOUSE |
| Isoform | — |
| PDB实体 | 1 |
| 链与序列区间 | 作者链 A； PDB构建体 2–370； UniProt 139–507 作者链 B； PDB构建体 2–370； UniProt 139–507 作者链 C； PDB构建体 2–370； UniProt 139–507 作者链 D； PDB构建体 2–370； UniProt 139–507 作者链 E； PDB构建体 2–370； UniProt 139–507 作者链 F； PDB构建体 2–370； UniProt 139–507 |
页面优先展示蛋白身份、当前 assembly、共同组分、聚集状态和跨 PDB 结构链接。 链映射与序列区间收在“数据证据”中；数据库内部编号、导入时间和 assembly 操作表达式仅用于维护，因此不在读者页面展示。
| 条目编号 entry_id | 5n6i |
| 沉积日期 deposition_date | 2017-02-15 |
| 结构标题 title | Crystal structure of mouse cGAS in complex with 39 bp DNA |
| 关键词 keywords | ;nucleotidyltransferase, cyclic GMP-AMP synthase, cGAS, DNA-binding, activator DNA, pattern recognition receptor, innate immune response, viral DNA recognition, TRANSFERASE ;; TRANSFERASE |
| 实验方法 method | X-RAY DIFFRACTION |
页面只读取最新 assembly 计算结果。每一条曲线都对应明确的 PDB、official biological assembly 和 coordinate model。
Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)
| Rg（Guinier） | 56.96 Å |
| Rg（电子密度） | 57.78 Å |
| 总 Rg | 57.66 Å |
| 原子数 | 22083 |
| 残基数 | 2354 |
| 排除体积 | 382680 ų |
| 最大 q | 0.500 Å⁻¹ |
| 结构域编号 domain_id | 5n6iA01 |
| 类 Class class | 1 — Mainly Alpha |
| 架构 Architecture architecture | 10 — Orthogonal Bundle |
| 拓扑 Topology topology | 1410 — Poly(a)-polymerase, middle domain |
| 同源超家族 H-superfamily homologous superfamily | 40 — |
| 结构域编号 domain_id | 5n6iA02 |
| 类 Class class | 3 — Alpha Beta |
| 架构 Architecture architecture | 30 — 2-Layer Sandwich |
| 拓扑 Topology topology | 460 — Beta Polymerase; domain 2 |
| 同源超家族 H-superfamily homologous superfamily | 90 — |
| 结构域编号 domain_id | 5n6iB01 |
| 类 Class class | 1 — Mainly Alpha |
| 架构 Architecture architecture | 10 — Orthogonal Bundle |
| 拓扑 Topology topology | 1410 — Poly(a)-polymerase, middle domain |
| 同源超家族 H-superfamily homologous superfamily | 40 — |
| 结构域编号 domain_id | 5n6iB02 |
| 类 Class class | 3 — Alpha Beta |
| 架构 Architecture architecture | 30 — 2-Layer Sandwich |
| 拓扑 Topology topology | 460 — Beta Polymerase; domain 2 |
| 同源超家族 H-superfamily homologous superfamily | 90 — |
| 结构域编号 domain_id | 5n6iC01 |
| 类 Class class | 1 — Mainly Alpha |
| 架构 Architecture architecture | 10 — Orthogonal Bundle |
| 拓扑 Topology topology | 1410 — Poly(a)-polymerase, middle domain |
| 同源超家族 H-superfamily homologous superfamily | 40 — |
| 结构域编号 domain_id | 5n6iC02 |
| 类 Class class | 3 — Alpha Beta |
| 架构 Architecture architecture | 30 — 2-Layer Sandwich |
| 拓扑 Topology topology | 460 — Beta Polymerase; domain 2 |
| 同源超家族 H-superfamily homologous superfamily | 90 — |
| 结构域编号 domain_id | 5n6iD01 |
| 类 Class class | 1 — Mainly Alpha |
| 架构 Architecture architecture | 10 — Orthogonal Bundle |
| 拓扑 Topology topology | 1410 — Poly(a)-polymerase, middle domain |
| 同源超家族 H-superfamily homologous superfamily | 40 — |
| 结构域编号 domain_id | 5n6iD02 |
| 类 Class class | 3 — Alpha Beta |
| 架构 Architecture architecture | 30 — 2-Layer Sandwich |
| 拓扑 Topology topology | 460 — Beta Polymerase; domain 2 |
| 同源超家族 H-superfamily homologous superfamily | 90 — |
| 结构域编号 domain_id | 5n6iE01 |
| 类 Class class | 1 — Mainly Alpha |
| 架构 Architecture architecture | 10 — Orthogonal Bundle |
| 拓扑 Topology topology | 1410 — Poly(a)-polymerase, middle domain |
| 同源超家族 H-superfamily homologous superfamily | 40 — |
| 结构域编号 domain_id | 5n6iE02 |
| 类 Class class | 3 — Alpha Beta |
| 架构 Architecture architecture | 30 — 2-Layer Sandwich |
| 拓扑 Topology topology | 460 — Beta Polymerase; domain 2 |
| 同源超家族 H-superfamily homologous superfamily | 90 — |
| 结构域编号 domain_id | 5n6iF01 |
| 类 Class class | 1 — Mainly Alpha |
| 架构 Architecture architecture | 10 — Orthogonal Bundle |
| 拓扑 Topology topology | 1410 — Poly(a)-polymerase, middle domain |
| 同源超家族 H-superfamily homologous superfamily | 40 — |
| 结构域编号 domain_id | 5n6iF02 |
| 类 Class class | 3 — Alpha Beta |
| 架构 Architecture architecture | 30 — 2-Layer Sandwich |
| 拓扑 Topology topology | 460 — Beta Polymerase; domain 2 |
| 同源超家族 H-superfamily homologous superfamily | 90 — |