Homo sapiens
| Assembly | Physical composition | Protein state | Molecular copy count | Associated components | Data consistency |
|---|---|---|---|---|---|
| 1 | Protein heterocomplex | Heteromer | Protein 4 | Cullin-3 × 2 （Q13618） | Consistent with protein count |
| UniProt name | KEAP1_HUMAN |
| Isoform | — |
| PDB entities | 1 |
| Chains and sequence ranges | Author chain A； PDBConstruct 1–154； UniProt 51–204 |
Homo sapiens
| Assembly | Physical composition | Protein state | Molecular copy count | Associated components | Data consistency |
|---|---|---|---|---|---|
| 1 | Protein heterocomplex | Heteromer | Protein 4 | Kelch-like ECH-associated protein 1 × 2 （Q14145） | Consistent with protein count |
| UniProt name | CUL3_HUMAN |
| Isoform | — |
| PDB entities | 2 |
| Chains and sequence ranges | Author chain B； PDBConstruct 1–356； UniProt 26–381 |
The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.
| Entry ID entry_id | 5nlb |
| Deposition date deposition_date | 2017-04-04 |
| Structure title title | Crystal structure of human CUL3 N-terminal domain bound to KEAP1 BTB and 3-box |
| Keywords keywords | E3 ubiquitin ligase, ligase; LIGASE |
| Experimental Method method | X-RAY DIFFRACTION |
This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.
Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)
| Rg（Guinier） | 46.08 Å |
| Rg (electron density) | 46.74 Å |
| Total Rg | 46.73 Å |
| Atom count | 7764 |
| Residues | 1004 |
| Excluded volume | 137770 ų |
| Maximum q | 0.500 Å⁻¹ |
| Domain ID domain_id | 5nlbA01 |
| Class class | 3 — Alpha Beta |
| Architecture architecture | 30 — 2-Layer Sandwich |
| Topology topology | 710 — Potassium Channel Kv1.1; Chain A |
| Homologous superfamily homologous superfamily | 10 — Potassium Channel Kv1.1; Chain A |
| Domain ID domain_id | 5nlbB01 |
| Class class | 1 — Mainly Alpha |
| Architecture architecture | 20 — Up-down Bundle |
| Topology topology | 1310 — 5 helical Cullin repeat like |
| Homologous superfamily homologous superfamily | 10 — Cullin Repeats |
| Domain ID domain_id | 5nlbB02 |
| Class class | 1 — Mainly Alpha |
| Architecture architecture | 20 — Up-down Bundle |
| Topology topology | 1310 — 5 helical Cullin repeat like |
| Homologous superfamily homologous superfamily | 10 — Cullin Repeats |
| Domain ID domain_id | 5nlbB03 |
| Class class | 1 — Mainly Alpha |
| Architecture architecture | 20 — Up-down Bundle |
| Topology topology | 1310 — 5 helical Cullin repeat like |
| Homologous superfamily homologous superfamily | 10 — Cullin Repeats |