Guanylate-binding protein 1
Homo sapiens
当前结构中的状态
| Assembly | 物理组成 | 蛋白状态 | 分子拷贝数 | 共同组分 | 数据核对 |
|---|---|---|---|---|---|
| 1 | 蛋白单体 | 单体 | 蛋白 1 | FARNESYL × 1 water × 1 | 与蛋白数一致 |
数据库中的同蛋白其他状态
查看构建体与数据证据
| UniProt名称 | GBP1_HUMAN |
| Isoform | — |
| PDB实体 | 1 |
| 链与序列区间 | 作者链 A； PDB构建体 3–594； UniProt 1–592 |
6k1z
Crystal structure of farnesylated hGBP1
1. 蛋白身份与相关结构 Protein Identity & Related Structures
页面优先展示蛋白身份、当前 assembly、共同组分、聚集状态和跨 PDB 结构链接。 链映射与序列区间收在“数据证据”中；数据库内部编号、导入时间和 assembly 操作表达式仅用于维护，因此不在读者页面展示。
2. 结构基本信息 2. Structure Basics
| 条目编号 entry_id | 6k1z |
| 沉积日期 deposition_date | 2019-05-13 |
| 结构标题 title | Crystal structure of farnesylated hGBP1 |
| 关键词 keywords | GBP farnesylation, HYDROLASE; HYDROLASE |
| 实验方法 method | X-RAY DIFFRACTION |
3. Official assembly/model 理论 SAXS Official SAXS Profiles
页面只读取最新 assembly 计算结果。每一条曲线都对应明确的 PDB、official biological assembly 和 coordinate model。
6k1z__assembly_1__model_1
Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)
6k1z__assembly_1__model_1 | I(q)
6k1z__assembly_1__model_1 | P(r) · Pending
| Rg（Guinier） | 37.19 Å |
| Rg（电子密度） | 38.34 Å |
| 总 Rg | 38.15 Å |
| 原子数 | 4403 |
| 残基数 | 544 |
| 排除体积 | 78919 ų |
| 最大 q | 0.500 Å⁻¹ |
4. 晶体学与实验 4. Crystallography & Experiment
5. 实体与聚合物信息 Entities & Polymers (3)
6. 折叠分类 (SCOP + CATH) 4 domains
SCOP 2.08 (2 domains)
| 结构域编号 domain_id | d6k1za1 |
| 类 Class class | c — Alpha and beta proteins (a/b) |
| 折叠类型 Fold fold | c.37 — P-loop containing nucleoside triphosphate hydrolases |
| 超家族 Superfamily superfamily | c.37.1 — P-loop containing nucleoside triphosphate hydrolases |
| 家族 Family family | c.37.1.8 — G proteins |
| 结构域编号 domain_id | d6k1za2 |
| 类 Class class | a — All alpha proteins |
| 折叠类型 Fold fold | a.114 — Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain |
| 超家族 Superfamily superfamily | a.114.1 — Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain |
| 家族 Family family | a.114.1.1 — Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain |
CATH v4.4 (2 domains)
| 结构域编号 domain_id | 6k1zA01 |
| 类 Class class | 3 — Alpha Beta |
| 架构 Architecture architecture | 40 — 3-Layer(aba) Sandwich |
| 拓扑 Topology topology | 50 — Rossmann fold |
| 同源超家族 H-superfamily homologous superfamily | 300 — P-loop containing nucleotide triphosphate hydrolases |
| 结构域编号 domain_id | 6k1zA02 |
| 类 Class class | 1 — Mainly Alpha |
| 架构 Architecture architecture | 20 — Up-down Bundle |
| 拓扑 Topology topology | 1000 — Signaling Protein - Interferon-induced Guanylate-binding Protein 1; Chain A, domain 1 |
| 同源超家族 H-superfamily homologous superfamily | 10 — Guanylate-binding protein, C-terminal domain |