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6m3d

X-ray crystal structure of tandemly connected engrailed homeodomains (EHD) with R53A mutations and DNA complex

Method: X-RAY DIFFRACTION
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1. Protein Identity and Related Structures Protein Identity & Related Structures

Segmentation polarity homeobox protein engrailed,Segmentation polarity homeobox protein engrailed

Drosophila melanogaster

UniProt P02836

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–DNA Monomer Protein 1 DNA 2 ;DNA (5'-D(*TP*AP*AP*TP*CP*CP*TP*AP*AP*TP*CP*C)-3') ; × 1 ;DNA (5'-D(*GP*GP*AP*TP*TP*AP*GP*GP*AP*TP*TP*A)-3') ; × 1 SODIUM ION × 1 water × 3 Consistent with all polymers

Other States of the Same Protein in the Database

Monomer
1enh 1p7i 1p7i 1p7i 1p7i 1p7j 1p7j 1p7j 1p7j 1ztr 2jwt 2p81

13 assemblies; showing the first 12

Homodimer

None

Homotetramer

None

Other homooligomers

None

Heteromeric or nucleic-acid complex
1du0 1hdd 2hdd 2hos 2hot 3hdd 6m3d 9yzq

8 assemblies

View Construct and Data Evidence
UniProt name HMEN_DROME
Isoform —
PDB entities 3
Chains and sequence ranges Author chain C； PDBConstruct 22–81； UniProt 453–512 Author chain C； PDBConstruct 87–146； UniProt 453–512

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

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2. Structure Basics 2. Structure Basics

Entry ID entry_id6m3d
Deposition date deposition_date2020-03-03
Structure title titleX-ray crystal structure of tandemly connected engrailed homeodomains (EHD) with R53A mutations and DNA complex
Keywords keywordsHOMEODOMAIN FOLD, PROTEIN-DNA COMPLEX, GENOME EDITING, DNA BINDING PROTEIN-DNA complex; DNA BINDING PROTEIN/DNA
Experimental Method methodX-RAY DIFFRACTION
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3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

6m3d__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

6m3d__assembly_1__model_1 | I(q)

10-2 10-1 105 106 107 q (1/Angstrom) I(q)
100 plotted points; both axes use logarithmic scales.

6m3d__assembly_1__model_1 | P(r) · Pending

The new assembly/model P(r) has not been calculated yet This placeholder does not display legacy data r (Angstrom) P(r)
P(r) will be calculated and displayed separately for the same assembly/model.
Rg（Guinier）18.92 Å
Rg (electron density)18.40 Å
Total Rg19.17 Å
Atom count1400
Residues132
Excluded volume23322 ų
Maximum q0.500 Å⁻¹
Assembly Model Structure unit Oligomeric description Status CRYSOL Actions
1 1 6m3d__assembly_1__model_1 trimeric （3） Success 4.1.3-1-20251215 (887e7ef) View Download
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4. Crystallography and Experiment 4. Crystallography & Experiment

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5. Entities and Polymers Entities & Polymers (5)

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7. Citations (1)