6qnu

Human Adenovirus type 3 fiber knob in complex with two copies of Desmoglein-2

Method: ELECTRON MICROSCOPY
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1. Protein Identity and Related Structures Protein Identity & Related Structures

Fiber protein

Human adenovirus B serotype 3

UniProt P04501

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein heterocomplex Heteromer Protein 5 Desmoglein-2 × 2 (Q14126) Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name SPIKE_ADE03
Isoform —
PDB entities 1
Chains and sequence ranges Author chain A; PDBConstruct 1–189; UniProt 130–318 Author chain B; PDBConstruct 1–189; UniProt 130–318 Author chain C; PDBConstruct 1–189; UniProt 130–318

Desmoglein-2

Homo sapiens

UniProt Q14126

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein heterocomplex Heteromer Protein 5 Fiber protein × 3 (P04501) Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name DSG2_HUMAN
Isoform —
PDB entities 2
Chains and sequence ranges Author chain D; PDBConstruct 1–224; UniProt 157–380 Author chain E; PDBConstruct 1–224; UniProt 157–380

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

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2. Structure Basics 2. Structure Basics

Entry ID entry_id6qnu
Deposition date deposition_date2019-02-12
Structure title titleHuman Adenovirus type 3 fiber knob in complex with two copies of Desmoglein-2
Keywords keywordsvirus receptor, adenovirus, vector, VIRAL PROTEIN; VIRAL PROTEIN
Experimental Method methodELECTRON MICROSCOPY
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3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

6qnu__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

6qnu__assembly_1__model_1 | I(q)

10-2 10-1 106 107 108 q (1/Angstrom) I(q)
100 plotted points; both axes use logarithmic scales.

6qnu__assembly_1__model_1 | P(r) · Pending

The new assembly/model P(r) has not been calculated yet This placeholder does not display legacy data r (Angstrom) P(r)
P(r) will be calculated and displayed separately for the same assembly/model.
Rg(Guinier)32.27 Å
Rg (electron density)31.24 Å
Total Rg32.02 Å
Atom count7250
Residues920
Excluded volume129860 ų
Maximum q0.500 Å⁻¹
Assembly Model Structure unit Oligomeric description Status CRYSOL Actions
1 1 6qnu__assembly_1__model_1 pentameric (5) Success 4.1.3-1-20251215 (887e7ef) View Download
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4. Crystallography and Experiment 4. Crystallography & Experiment

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5. Entities and Polymers Entities & Polymers (2)

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6. Fold Classification (SCOP + CATH) 3 domains

CATH v4.4 (3 domains)

Domain ID domain_id6qnuA00
Class class2 — Mainly Beta
Architecture architecture60 — Sandwich
Topology topology90 — Adenovirus Type 5 Fiber Protein (Receptor Binding Domain)
Homologous superfamily homologous superfamily10 — Adenovirus pIV-related, attachment domain
Domain ID domain_id6qnuB00
Class class2 — Mainly Beta
Architecture architecture60 — Sandwich
Topology topology90 — Adenovirus Type 5 Fiber Protein (Receptor Binding Domain)
Homologous superfamily homologous superfamily10 — Adenovirus pIV-related, attachment domain
Domain ID domain_id6qnuC00
Class class2 — Mainly Beta
Architecture architecture60 — Sandwich
Topology topology90 — Adenovirus Type 5 Fiber Protein (Receptor Binding Domain)
Homologous superfamily homologous superfamily10 — Adenovirus pIV-related, attachment domain
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7. Citations (1)