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7a0d

The Crystal Structure of Bovine Thrombin in complex with Hirudin (C16U/C28U) at 1.6 Angstroms Resolution

Method: X-RAY DIFFRACTION
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1. Protein Identity and Related Structures Protein Identity & Related Structures

Prothrombin

OrganismNot specified

UniProt P00735

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Other combination Heteromer Protein 3 其他Polymer 1 Hirudin variant-1 × 1 （P01050） 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose × 1 SODIUM ION × 1 water × 3 Consistent with protein count

Other States of the Same Protein in the Database

Monomer
1mkw 1mkx 1mkx 2pf1 2pf2 2spt

6 assemblies

Homodimer
1etr 1ets 1ett 1mkw 1mkx 1mkx 1uvt 1uvu 3pmb 3pmb

10 assemblies

Homotetramer
1mkx

1 assemblies

Other homooligomers
1mkx

1 assemblies

Heteromeric or nucleic-acid complex
1a0h 1avg 1bbr 1bbr 1bbr 1bbr 1hrt 1id5 1nl1 1nl2 1tbq 1tbq

38 assemblies; showing the first 12

View Construct and Data Evidence
UniProt name THRB_BOVIN
Isoform —
PDB entities 1, 3
Chains and sequence ranges Author chain HHH； PDBConstruct 1–259； UniProt 367–625 Author chain LLL； PDBConstruct 1–49； UniProt 318–366

Hirudin variant-1

OrganismNot specified

UniProt P01050

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Other combination Heteromer Protein 3 其他Polymer 1 Prothrombin × 1 （P00735） Prothrombin × 1 （P00735） 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose × 1 SODIUM ION × 1 water × 3 Consistent with protein count

Other States of the Same Protein in the Database

Monomer
1hic 2hir 2joo 4hir 5hir 6hir

6 assemblies

Homodimer

None

Homotetramer

None

Other homooligomers

None

Heteromeric or nucleic-acid complex
1ad8 1ay6 1bcu 1h8d 1h8i 1hrt 1hxe 1hxf 2pw8 2v3o 2zc9 2zda

43 assemblies; showing the first 12

View Construct and Data Evidence
UniProt name HIRV1_HIRME
Isoform —
PDB entities 2
Chains and sequence ranges Author chain III； PDBConstruct 1–65； UniProt 1–65

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

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2. Structure Basics 2. Structure Basics

Entry ID entry_id7a0d
Deposition date deposition_date2020-08-07
Structure title titleThe Crystal Structure of Bovine Thrombin in complex with Hirudin (C16U/C28U) at 1.6 Angstroms Resolution
Keywords keywordsHydrolase, Inhibitor, Hirudin, Thrombin, Selenocysteine, Derivative; HYDROLASE
Experimental Method methodX-RAY DIFFRACTION
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3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

7a0d__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

7a0d__assembly_1__model_1 | I(q)

10-2 10-1 105 106 107 q (1/Angstrom) I(q)
100 plotted points; both axes use logarithmic scales.

7a0d__assembly_1__model_1 | P(r) · Pending

The new assembly/model P(r) has not been calculated yet This placeholder does not display legacy data r (Angstrom) P(r)
P(r) will be calculated and displayed separately for the same assembly/model.
Rg（Guinier）20.95 Å
Rg (electron density)19.73 Å
Total Rg20.80 Å
Atom count2830
Residues356
Excluded volume50214 ų
Maximum q0.500 Å⁻¹
Assembly Model Structure unit Oligomeric description Status CRYSOL Actions
1 1 7a0d__assembly_1__model_1 trimeric （3） Success 4.1.3-1-20251215 (887e7ef) View Download
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4. Crystallography and Experiment 4. Crystallography & Experiment

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5. Entities and Polymers Entities & Polymers (6)

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7. Citations (1)