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7bx7

Cryo-EM structure of amyloid fibril formed by hnRNPA1 low complexity domain

Method: ELECTRON MICROSCOPY
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1. Protein Identity and Related Structures Protein Identity & Related Structures

Heterogeneous nuclear ribonucleoprotein A1

Homo sapiens

UniProt P09651

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein homooligomer Homooligomer Protein 6 No other associated polymer Consistent with protein count

Other States of the Same Protein in the Database

Monomer
1ha1 1l3k 1up1 2lyv 5zgl 5zgl 9f1s 9f4d 9f4g 9f4h 9f4j 9f4k

44 assemblies; showing the first 12

Homodimer

None

Homotetramer

None

Other homooligomers
7bx7 7zj2 9gkf

3 assemblies

Heteromeric or nucleic-acid complex
1pgz 1po6 1u1k 1u1l 1u1m 1u1n 1u1o 1u1p 1u1q 1u1r 2h4m 2up1

21 assemblies; showing the first 12

View Construct and Data Evidence
UniProt name ROA1_HUMAN
Isoform P09651-2
PDB entities 1
Chains and sequence ranges Author chain A； PDBConstruct 1–135； UniProt 186–320 Author chain B； PDBConstruct 1–135； UniProt 186–320 Author chain C； PDBConstruct 1–135； UniProt 186–320 Author chain D； PDBConstruct 1–135； UniProt 186–320 Author chain E； PDBConstruct 1–135； UniProt 186–320 Author chain F； PDBConstruct 1–135； UniProt 186–320

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

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2. Structure Basics 2. Structure Basics

Entry ID entry_id7bx7
Deposition date deposition_date2020-04-17
Structure title titleCryo-EM structure of amyloid fibril formed by hnRNPA1 low complexity domain
Keywords keywordsamyloid fibril, PROTEIN FIBRIL; PROTEIN FIBRIL
Experimental Method methodELECTRON MICROSCOPY
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3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

7bx7__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

7bx7__assembly_1__model_1 | I(q)

10-2 10-1 105 106 107 q (1/Angstrom) I(q)
100 plotted points; both axes use logarithmic scales.

7bx7__assembly_1__model_1 | P(r) · Pending

The new assembly/model P(r) has not been calculated yet This placeholder does not display legacy data r (Angstrom) P(r)
P(r) will be calculated and displayed separately for the same assembly/model.
Rg（Guinier）20.81 Å
Rg (electron density)20.65 Å
Total Rg21.31 Å
Atom count1896
Residues270
Excluded volume31540 ų
Maximum q0.500 Å⁻¹
Assembly Model Structure unit Oligomeric description Status CRYSOL Actions
1 1 7bx7__assembly_1__model_1 hexameric （6） Success 4.1.3-1-20251215 (887e7ef) View Download
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4. Crystallography and Experiment 4. Crystallography & Experiment

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5. Entities and Polymers Entities & Polymers (1)

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7. Citations (1)