7ndq

Gag:02 TCR in complex with HLA-E.

Method: X-RAY DIFFRACTION

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1. Protein Identity and Related Structures Protein Identity & Related Structures

HLA class I histocompatibility antigen, alpha chain E

Homo sapiens

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Insufficient information	Heteromer	Protein 5	Beta-2-microglobulin × 1 （P61769） Gag6V × 1 （B6S6I4） TCR Gag:02-alpha,TCR Gag:02-alpha,TCR Gag:02-alpha × 1 （A0A075B6U7,A0A0B4J268,P0DSE1） ;T cell receptor beta variable 7-9,M1-specific T cell receptor beta chain,T cell receptor beta variable 7-9,M1-specific T cell receptor beta chain,T cell receptor beta variable 7-9,M1-specific T cell receptor beta chain ; × 1 （A0A0J9YX06,K7N5M4,P04435） water × 4	Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	HLAE_HUMAN
Isoform	—
PDB entities	1
Chains and sequence ranges	Author chain AAA； PDBConstruct 2–277； UniProt 22–297

Beta-2-microglobulin

Homo sapiens

UniProt P61769

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Insufficient information	Heteromer	Protein 5	HLA class I histocompatibility antigen, alpha chain E × 1 （P13747） Gag6V × 1 （B6S6I4） TCR Gag:02-alpha,TCR Gag:02-alpha,TCR Gag:02-alpha × 1 （A0A075B6U7,A0A0B4J268,P0DSE1） ;T cell receptor beta variable 7-9,M1-specific T cell receptor beta chain,T cell receptor beta variable 7-9,M1-specific T cell receptor beta chain,T cell receptor beta variable 7-9,M1-specific T cell receptor beta chain ; × 1 （A0A0J9YX06,K7N5M4,P04435） water × 4	Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	B2MG_HUMAN
Isoform	—
PDB entities	2
Chains and sequence ranges	Author chain BBB； PDBConstruct 2–100； UniProt 21–119

Gag6V

OrganismNot specified

UniProt B6S6I4

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Insufficient information	Heteromer	Protein 5	HLA class I histocompatibility antigen, alpha chain E × 1 （P13747） Beta-2-microglobulin × 1 （P61769） TCR Gag:02-alpha,TCR Gag:02-alpha,TCR Gag:02-alpha × 1 （A0A075B6U7,A0A0B4J268,P0DSE1） ;T cell receptor beta variable 7-9,M1-specific T cell receptor beta chain,T cell receptor beta variable 7-9,M1-specific T cell receptor beta chain,T cell receptor beta variable 7-9,M1-specific T cell receptor beta chain ; × 1 （A0A0J9YX06,K7N5M4,P04435） water × 4	Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	B6S6I4_9HIV1
Isoform	—
PDB entities	3
Chains and sequence ranges	Author chain CCC； PDBConstruct 1–9； UniProt 275–283

TCR Gag:02-alpha,TCR Gag:02-alpha,TCR Gag:02-alpha

Homo sapiens

UniProt A0A075B6U7

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Insufficient information	Heteromer	Protein 5	HLA class I histocompatibility antigen, alpha chain E × 1 （P13747） Beta-2-microglobulin × 1 （P61769） Gag6V × 1 （B6S6I4） ;T cell receptor beta variable 7-9,M1-specific T cell receptor beta chain,T cell receptor beta variable 7-9,M1-specific T cell receptor beta chain,T cell receptor beta variable 7-9,M1-specific T cell receptor beta chain ; × 1 （A0A0J9YX06,K7N5M4,P04435） water × 4	Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	A0A075B6U7_HUMAN
Isoform	—
PDB entities	4
Chains and sequence ranges	Author chain DDD； PDBConstruct 96–113； UniProt 4–21

TCR Gag:02-alpha,TCR Gag:02-alpha,TCR Gag:02-alpha

Homo sapiens

UniProt A0A0B4J268

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Insufficient information	Heteromer	Protein 5	HLA class I histocompatibility antigen, alpha chain E × 1 （P13747） Beta-2-microglobulin × 1 （P61769） Gag6V × 1 （B6S6I4） ;T cell receptor beta variable 7-9,M1-specific T cell receptor beta chain,T cell receptor beta variable 7-9,M1-specific T cell receptor beta chain,T cell receptor beta variable 7-9,M1-specific T cell receptor beta chain ; × 1 （A0A0J9YX06,K7N5M4,P04435） water × 4	Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	TVA4_HUMAN
Isoform	—
PDB entities	4
Chains and sequence ranges	Author chain DDD； PDBConstruct 2–92； UniProt 18–108

TCR Gag:02-alpha,TCR Gag:02-alpha,TCR Gag:02-alpha

Homo sapiens

UniProt P0DSE1

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Insufficient information	Heteromer	Protein 5	HLA class I histocompatibility antigen, alpha chain E × 1 （P13747） Beta-2-microglobulin × 1 （P61769） Gag6V × 1 （B6S6I4） ;T cell receptor beta variable 7-9,M1-specific T cell receptor beta chain,T cell receptor beta variable 7-9,M1-specific T cell receptor beta chain,T cell receptor beta variable 7-9,M1-specific T cell receptor beta chain ; × 1 （A0A0J9YX06,K7N5M4,P04435） water × 4	Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	TRAR1_HUMAN
Isoform	—
PDB entities	4
Chains and sequence ranges	Author chain DDD； PDBConstruct 115–199； UniProt 129–213

;T cell receptor beta variable 7-9,M1-specific T cell receptor beta chain,T cell receptor beta variable 7-9,M1-specific T cell receptor beta chain,T cell receptor beta variable 7-9,M1-specific T cell receptor beta chain ;

Homo sapiens

UniProt A0A0J9YX06

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Insufficient information	Heteromer	Protein 5	HLA class I histocompatibility antigen, alpha chain E × 1 （P13747） Beta-2-microglobulin × 1 （P61769） Gag6V × 1 （B6S6I4） TCR Gag:02-alpha,TCR Gag:02-alpha,TCR Gag:02-alpha × 1 （A0A075B6U7,A0A0B4J268,P0DSE1） water × 4	Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	TJB12_HUMAN
Isoform	—
PDB entities	5
Chains and sequence ranges	Author chain EEE； PDBConstruct 101–114； UniProt 2–15

;T cell receptor beta variable 7-9,M1-specific T cell receptor beta chain,T cell receptor beta variable 7-9,M1-specific T cell receptor beta chain,T cell receptor beta variable 7-9,M1-specific T cell receptor beta chain ;

Homo sapiens

UniProt K7N5M4

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Insufficient information	Heteromer	Protein 5	HLA class I histocompatibility antigen, alpha chain E × 1 （P13747） Beta-2-microglobulin × 1 （P61769） Gag6V × 1 （B6S6I4） TCR Gag:02-alpha,TCR Gag:02-alpha,TCR Gag:02-alpha × 1 （A0A075B6U7,A0A0B4J268,P0DSE1） water × 4	Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	K7N5M4_HUMAN
Isoform	—
PDB entities	5
Chains and sequence ranges	Author chain EEE； PDBConstruct 115–244； UniProt 120–249

;T cell receptor beta variable 7-9,M1-specific T cell receptor beta chain,T cell receptor beta variable 7-9,M1-specific T cell receptor beta chain,T cell receptor beta variable 7-9,M1-specific T cell receptor beta chain ;

Homo sapiens

UniProt P04435

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Insufficient information	Heteromer	Protein 5	HLA class I histocompatibility antigen, alpha chain E × 1 （P13747） Beta-2-microglobulin × 1 （P61769） Gag6V × 1 （B6S6I4） TCR Gag:02-alpha,TCR Gag:02-alpha,TCR Gag:02-alpha × 1 （A0A075B6U7,A0A0B4J268,P0DSE1） water × 4	Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	TVB79_HUMAN
Isoform	—
PDB entities	5
Chains and sequence ranges	Author chain EEE； PDBConstruct 2–97； UniProt 20–115

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

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2. Structure Basics 2. Structure Basics

Entry ID entry_id	7ndq
Deposition date deposition_date	2021-02-02
Structure title title	Gag:02 TCR in complex with HLA-E.
Keywords keywords	TCR-pHLA complex, non-natural amino acid, IMMUNE SYSTEM; IMMUNE SYSTEM
Experimental Method method	X-RAY DIFFRACTION

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3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

7ndq__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

7ndq__assembly_1__model_1 | I(q)

100 plotted points; both axes use logarithmic scales.

7ndq__assembly_1__model_1 | P(r) · Pending

P(r) will be calculated and displayed separately for the same assembly/model.

Rg（Guinier）	37.25 Å
Rg (electron density)	37.49 Å
Total Rg	37.63 Å
Atom count	6544
Residues	811
Excluded volume	114560 Å³
Maximum q	0.500 Å⁻¹

Assembly	Model	Structure unit	Oligomeric description	Status	CRYSOL	Actions
1	1	`7ndq__assembly_1__model_1`	pentameric （5）	Success	4.1.3-1-20251215 (887e7ef)	View Download

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4. Crystallography and Experiment 4. Crystallography & Experiment

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5. Entities and Polymers Entities & Polymers (6)

Entity 1 Entity 1 polymer

Description description	HLA class I histocompatibility antigen, alpha chain E
Molecular weight formula_weight	31955.2 kDa
Source method src_method	man
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	AAA
Atom count atom_count	6573

MGSHSLKYFHTSVSRPGRGEPRFISVGYVDDTQFVRFDNDAASPRMVPRAPWMEQEGSEYWDRETRSARDTAQIFRVNLRTLRGYYNQSEAGSHTLQWMHGCELGPDGRFLRGYEQFAYDGKDYLTLNEDLRSWTAVDTAAQISEQKSNDASEAEHQRAYLEDTCVEWLHKYLEKGKETLLHLEPPKTHVTHHPISDHEATLRCWALGFYPAEITLTWQQDGEGHTQDTELVETRPAGDGTFQKWAAVVVPSGEEQRYTCHVQHEGLPEPVTLRWKP

Source Source

Source organism organism	Homo sapiens
Common name common_name	Human
NCBI taxonomy ID ncbi_taxonomy_id	9606
Host organism host_organism	Escherichia coli

Entity 2 Entity 2 polymer

Description description	Beta-2-microglobulin
Molecular weight formula_weight	11879.4 kDa
Source method src_method	man
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	BBB

MIQRTPKIQVYSRHPAENGKSNFLNCYVSGFHPSDIEVDLLKNGERIEKVEHSDLSFSKDWSFYLLYYTEFTPTEKDEYACRVNHVTLSQPKIVKWDRDM

Source Source

Source organism organism	Homo sapiens
Common name common_name	Human
NCBI taxonomy ID ncbi_taxonomy_id	9606
Host organism host_organism	Escherichia coli

Entity 3 Entity 3 polymer

Description description	Gag6V
Molecular weight formula_weight	1066.3 kDa
Source method src_method	syn
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	CCC

RMYSPVSIL

Entity 4 Entity 4 polymer

Description description	TCR Gag:02-alpha,TCR Gag:02-alpha,TCR Gag:02-alpha
Molecular weight formula_weight	22074.5 kDa
Source method src_method	man
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	DDD

MLAKTTQPISMDSYEGQEVNITCSHNNIATNDYITWYQQFPSQGPRFIIQGYKTKVTNEVASLFIPADRKSSTLSLPRVSLSDTAVYYCLVGSSFNQGGKLIFGQGTELSVKPNIQNPDPAVYQLRDSKSSDKSVCLFTDFDSQTNVSQSKDSDVYITDKCVLDMRSMDFKSNSAVAWSNKSDFACANAFNNSIIPEDT

Source Source

Source organism organism	Homo sapiens
Common name common_name	Human
NCBI taxonomy ID ncbi_taxonomy_id	9606
Host organism host_organism	Escherichia coli

Entity 5 Entity 5 polymer

Description description	;T cell receptor beta variable 7-9,M1-specific T cell receptor beta chain,T cell receptor beta variable 7-9,M1-specific T cell receptor beta chain,T cell receptor beta variable 7-9,M1-specific T cell receptor beta chain ;
Molecular weight formula_weight	27914.0 kDa
Source method src_method	man
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	EEE

MDTGVSQNPRHKITKRGQNVTFRCDPISEHNRLYWYRQTLGQGPEFLTYFQNEAQLEKSRLLSDRFSAERPKGSFSTLEIQRTEQGDSAMYLCASSLGREYGYTFGSGTRLTVVEDLNKVFPPEVAVFEPSEAEISHTQKATLVCLATGFYPDHVELSWWVNGKEVHSGVCTDPQPLKEQPALNDSRYALSSRLRVSATFWQDPRNHFRCQVQFYGLSENDEWTQDRAKPVTQIVSAEAWGRAD

Source Source

Source organism organism	Homo sapiens
Common name common_name	Human
NCBI taxonomy ID ncbi_taxonomy_id	9606
Host organism host_organism	Escherichia coli

Entity 6 Entity 6 water

Description description	water
Molecular weight formula_weight	18.0 kDa
Source method src_method	nat
Copy count entity_count	13

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Unit-cell length a length_a	89.391 Å
Unit-cell length b length_b	89.391 Å
Unit-cell length c length_c	293.298 Å
Unit-cell angle α angle_alpha	90.00 °
Unit-cell angle β angle_beta	90.00 °
Unit-cell angle γ angle_gamma	90.00 °
Molecules per unit cell Z z_pdb	8

Space group space_group	P 43 21 2
Space-group number int_tables_number	96
Crystal system crystal_system	—

Resolution resolution	2.551 Å
Low-resolution limit resolution_low	76.445 Å
R factor r_factor	—
R_work r_work	0.2397
R_free r_free	0.2963

Gag:02 TCR in complex with HLA-E.

1. Protein Identity and Related Structures Protein Identity & Related Structures

HLA class I histocompatibility antigen, alpha chain E

State in the Current Structure

Other States of the Same Protein in the Database

Monomer

Homodimer

Homotetramer

Other homooligomers

Heteromeric or nucleic-acid complex

Beta-2-microglobulin

State in the Current Structure

Other States of the Same Protein in the Database

Monomer

Homodimer

Homotetramer

Other homooligomers

Heteromeric or nucleic-acid complex

Gag6V

State in the Current Structure

Other States of the Same Protein in the Database

Monomer

Homodimer

Homotetramer

Other homooligomers

Heteromeric or nucleic-acid complex

TCR Gag:02-alpha,TCR Gag:02-alpha,TCR Gag:02-alpha

State in the Current Structure

Other States of the Same Protein in the Database

Monomer

Homodimer

Homotetramer

Other homooligomers

Heteromeric or nucleic-acid complex

TCR Gag:02-alpha,TCR Gag:02-alpha,TCR Gag:02-alpha

State in the Current Structure

Other States of the Same Protein in the Database

Monomer

Homodimer

Homotetramer

Other homooligomers

Heteromeric or nucleic-acid complex

TCR Gag:02-alpha,TCR Gag:02-alpha,TCR Gag:02-alpha

State in the Current Structure

Other States of the Same Protein in the Database

Monomer

Homodimer

Homotetramer

Other homooligomers

Heteromeric or nucleic-acid complex

;T cell receptor beta variable 7-9,M1-specific T cell receptor beta chain,T cell receptor beta variable 7-9,M1-specific T cell receptor beta chain,T cell receptor beta variable 7-9,M1-specific T cell receptor beta chain ;

State in the Current Structure

Other States of the Same Protein in the Database

Monomer

Homodimer

Homotetramer

Other homooligomers

Heteromeric or nucleic-acid complex

;T cell receptor beta variable 7-9,M1-specific T cell receptor beta chain,T cell receptor beta variable 7-9,M1-specific T cell receptor beta chain,T cell receptor beta variable 7-9,M1-specific T cell receptor beta chain ;

State in the Current Structure

Other States of the Same Protein in the Database

Monomer

Homodimer

Homotetramer

Other homooligomers

Heteromeric or nucleic-acid complex

;T cell receptor beta variable 7-9,M1-specific T cell receptor beta chain,T cell receptor beta variable 7-9,M1-specific T cell receptor beta chain,T cell receptor beta variable 7-9,M1-specific T cell receptor beta chain ;

State in the Current Structure

Other States of the Same Protein in the Database

Monomer

Homodimer

Homotetramer

Other homooligomers

Heteromeric or nucleic-acid complex

2. Structure Basics 2. Structure Basics

3. Official assembly/model SAXS Official SAXS Profiles

7ndq__assembly_1__model_1

7ndq__assembly_1__model_1 | I(q)

7ndq__assembly_1__model_1 | P(r) · Pending

4. Crystallography and Experiment 4. Crystallography & Experiment