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7ocd

Resting state GluA1/A2 heterotetramer in complex with auxiliary subunit TARP gamma 8 (LBD-TMD)

Method: ELECTRON MICROSCOPY
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1. Protein Identity and Related Structures Protein Identity & Related Structures

Isoform Flip of Glutamate receptor 1

Rattus norvegicus

UniProt P19490

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein heterocomplex Heteromer Protein 6 Glutamate receptor 2 × 2 （P19491） Voltage-dependent calcium channel gamma-8 subunit × 2 （Q8VHW5） 6-nitro-2,3-bis(oxidanylidene)-1,4-dihydrobenzo[f]quinoxaline-7-sulfonamide × 4 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE × 6 Consistent with protein count

Other States of the Same Protein in the Database

Monomer

None

Homodimer

None

Homotetramer

None

Other homooligomers

None

Heteromeric or nucleic-acid complex
3saj 3saj 6njl 6njn 6qkc 6qkz 7oca 7occ 7occ 7ocd 7oce 7ocf

35 assemblies; showing the first 12

View Construct and Data Evidence
UniProt name GRIA1_RAT
Isoform P19490-2
PDB entities 1
Chains and sequence ranges Author chain A； PDBConstruct 1–915； UniProt 1–907 Author chain C； PDBConstruct 1–915； UniProt 1–907

Glutamate receptor 2

Rattus norvegicus

UniProt P19491

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein heterocomplex Heteromer Protein 6 Isoform Flip of Glutamate receptor 1 × 2 （P19490） Voltage-dependent calcium channel gamma-8 subunit × 2 （Q8VHW5） 6-nitro-2,3-bis(oxidanylidene)-1,4-dihydrobenzo[f]quinoxaline-7-sulfonamide × 4 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE × 6 Consistent with protein count

Other States of the Same Protein in the Database

Monomer
1ftj 1ftj 1ftj 1ftk 1ftm 1ftm 1ftm 1fto 1fto 1fw0 1gr2 1lb8

57 assemblies; showing the first 12

Homodimer
1ftj 1ftl 1ftm 1m5b 1m5b 1m5c 1m5d 1m5e 1m5e 1m5f 1m5f 1mm6

242 assemblies; showing the first 12

Homotetramer
2i3v 4u1w 4u1x 4u1y 4u2p 4u2q 4u2r 4uq6 4uqj 4uqk 5jei 5kbv

48 assemblies; showing the first 12

Other homooligomers
1ftj 1ftm 1m5b 1m5e 1m5f 1ms7 1mxu 1mxv 1mxw 1mxx 1mxy 1mxz

21 assemblies; showing the first 12

Heteromeric or nucleic-acid complex
3h5v 3hsy 3kg2 4u4f 4u4g 4u5b 4u5c 4u5d 4u5e 4u5f 5fwx 5fwx

115 assemblies; showing the first 12

View Construct and Data Evidence
UniProt name GRIA2_RAT
Isoform P19491-2
PDB entities 2
Chains and sequence ranges Author chain B； PDBConstruct 1–860； UniProt 1–860 Author chain D； PDBConstruct 1–860； UniProt 1–860

Voltage-dependent calcium channel gamma-8 subunit

Rattus norvegicus

UniProt Q8VHW5

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein heterocomplex Heteromer Protein 6 Isoform Flip of Glutamate receptor 1 × 2 （P19490） Glutamate receptor 2 × 2 （P19491） 6-nitro-2,3-bis(oxidanylidene)-1,4-dihydrobenzo[f]quinoxaline-7-sulfonamide × 4 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE × 6 Consistent with protein count

Other States of the Same Protein in the Database

Monomer

None

Homodimer

None

Homotetramer

None

Other homooligomers

None

Heteromeric or nucleic-acid complex
6qkc 6qkz 7oca 7ocd 7oce 7ocf 7qhb 7qhh 8ayl 8aym 8ayn 8ayo

12 assemblies

View Construct and Data Evidence
UniProt name CCG8_RAT
Isoform —
PDB entities 3
Chains and sequence ranges Author chain I； PDBConstruct 2–417； UniProt 2–417 Author chain J； PDBConstruct 2–417； UniProt 2–417

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

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2. Structure Basics 2. Structure Basics

Entry ID entry_id7ocd
Deposition date deposition_date2021-04-26
Structure title titleResting state GluA1/A2 heterotetramer in complex with auxiliary subunit TARP gamma 8 (LBD-TMD)
Keywords keywordsAMPAR, ion channels, neurotransmission, MEMBRANE PROTEIN; MEMBRANE PROTEIN
Experimental Method methodELECTRON MICROSCOPY
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3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

7ocd__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

7ocd__assembly_1__model_1 | I(q)

10-2 10-1 106 107 108 q (1/Angstrom) I(q)
100 plotted points; both axes use logarithmic scales.

7ocd__assembly_1__model_1 | P(r) · Pending

The new assembly/model P(r) has not been calculated yet This placeholder does not display legacy data r (Angstrom) P(r)
P(r) will be calculated and displayed separately for the same assembly/model.
Rg（Guinier）43.20 Å
Rg (electron density)42.69 Å
Total Rg42.90 Å
Atom count13624
Residues1920
Excluded volume245980 ų
Maximum q0.500 Å⁻¹
Assembly Model Structure unit Oligomeric description Status CRYSOL Actions
1 1 7ocd__assembly_1__model_1 hexameric （6） Success 4.1.3-1-20251215 (887e7ef) View Download
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4. Crystallography and Experiment 4. Crystallography & Experiment

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5. Entities and Polymers Entities & Polymers (5)

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6. Fold Classification (SCOP + CATH) 2 domains

CATH v4.4 (2 domains)

Domain ID domain_id7ocdI01
Class class1 — Mainly Alpha
Architecture architecture20 — Up-down Bundle
Topology topology140 — Butyryl-CoA Dehydrogenase, subunit A; domain 3
Homologous superfamily homologous superfamily150 —
Domain ID domain_id7ocdJ01
Class class1 — Mainly Alpha
Architecture architecture20 — Up-down Bundle
Topology topology140 — Butyryl-CoA Dehydrogenase, subunit A; domain 3
Homologous superfamily homologous superfamily150 —
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7. Citations (1)