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7srk

Single chain trimer HLA-A*24:02 (Y108C, A163C) with 8mer peptide YPPVPETF

Method: X-RAY DIFFRACTION Dmax: 103.8 Å Quality: GOOD
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1. Protein Identity and Related Structures Protein Identity & Related Structures

RPA-related protein RADX peptide,Beta-2-microglobulin,MHC class I antigen chimera

Homo sapiens

UniProt A0A411J078

State in the Current Structure

Assembly Oligomeric State Construct Mutations and Modifications Ligands, Ions and Associated Components Method and Experimental Conditions Structure Quality
1 Insufficient information Heteromer Protein × 2 PDB declaration: dimeric（2） Consistent with protein copy count Chain A； UniProt 25–299 Mutation：Y108C, A163C VHH × 1 X-RAY DIFFRACTION X-ray crystallization conditions：VAPOR DIFFUSION, HANGING DROP；295 K；100 mM MES, pH 6.0, 200 mM KSCN, 18% Peg 3350 Resolution 2.50 Å R-free 0.260
2 Insufficient information Heteromer Protein × 2 PDB declaration: dimeric（2） Consistent with protein copy count Chain C； UniProt 25–299 Mutation：Y108C, A163C VHH × 1 X-RAY DIFFRACTION X-ray crystallization conditions：VAPOR DIFFUSION, HANGING DROP；295 K；100 mM MES, pH 6.0, 200 mM KSCN, 18% Peg 3350 Resolution 2.50 Å R-free 0.260

Other States of the Same Protein in the Database

Each row is a biological assembly of the same UniProt protein in another PDB entry. The “Difference from current entry” column identifies evidence-level differences; no tag means the currently parsed fields agree.

Other PDB Difference from Current Entry 7SRK Assembly / Oligomeric State Construct Mutations and Modifications Ligands, Ions and Non-polymers Method and Experimental Conditions Structure Quality
6XQA Crystal Structure of HLA A*2402 in complex with TYQWVLKNL, an 9-mer epitope from Influenza B virus Deposited 2020-07-09 Different construct Different mutation/modification Different oligomeric state Different experimental conditions Different structure-quality metrics Assembly 1 Protein heterocomplex Heteromer；Protein × 3 PDB declaration: trimeric
Chain A 25–302（278 aa）
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 5.6；277 K；24% PEG8000, 0.1 HEPES pH 7.5, 2% isopropanol, 5% w/v Polyvinylpyrrolidone K15
Resolution 2.16 Å R-free 0.229
6XQA Crystal Structure of HLA A*2402 in complex with TYQWVLKNL, an 9-mer epitope from Influenza B virus Deposited 2020-07-09 Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 2 Protein heterocomplex Heteromer；Protein × 3 PDB declaration: trimeric
Chain D 25–302（278 aa）
Not recorded MG MAGNESIUM ION × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 5.6；277 K；24% PEG8000, 0.1 HEPES pH 7.5, 2% isopropanol, 5% w/v Polyvinylpyrrolidone K15
Resolution 2.16 Å R-free 0.229
7EJL Complex Structure of HLA-A*2402 with the Peptide from HCoV(CoV-2) spike protein Deposited 2021-04-02 Different construct Different mutation/modification Different oligomeric state Different experimental conditions Different structure-quality metrics Assembly 1 Protein heterocomplex Heteromer；Protein × 3 PDB declaration: trimeric
Chain A 25–298（274 aa）
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 8.2；293 K；Na/K phosphate
Resolution 1.89 Å R-free 0.255
7EJM Complex Structure of HLA-A*2402 with the Peptide from HCoV(CoV-229E) spike protein Deposited 2021-04-02 Different construct Different mutation/modification Different oligomeric state Different experimental conditions Different structure-quality metrics Assembly 1 Protein heterocomplex Heteromer；Protein × 3 PDB declaration: trimeric
Chain A 25–298（274 aa）
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；293 K；Na citrate, PEG 3350
Resolution 1.71 Å R-free 0.221
7EJN Complex Structure of HLA-A*2402 with the Peptide from HCoV(CoV-HKU1) spike protein Deposited 2021-04-02 Different construct Different mutation/modification Different oligomeric state Different experimental conditions Different structure-quality metrics Assembly 1 Protein heterocomplex Heteromer；Protein × 3 PDB declaration: trimeric
Chain A 25–298（274 aa）
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 8.5；293 K；PEG 3350, Tris-HCl
Resolution 2.11 Å R-free 0.264
7JYU Crystal Structure of HLA-A*2402 in complex with IYFSPIRVTF, an 10-mer epitope from Influenza B virus Deposited 2020-09-01 Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein heterocomplex Heteromer；Protein × 3 PDB declaration: trimeric
Chain A 25–302（278 aa）
Not recorded MG MAGNESIUM ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 5.6；277 K；20% PEG 8000, 0.2 MgCl2, 0.1 Tris-HCl pH 8.5
Resolution 2.75 Å R-free 0.259
7JYU Crystal Structure of HLA-A*2402 in complex with IYFSPIRVTF, an 10-mer epitope from Influenza B virus Deposited 2020-09-01 Different construct Different mutation/modification Different oligomeric state Different experimental conditions Different structure-quality metrics Assembly 2 Protein heterocomplex Heteromer；Protein × 3 PDB declaration: trimeric
Chain D 25–302（278 aa）
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 5.6；277 K；20% PEG 8000, 0.2 MgCl2, 0.1 Tris-HCl pH 8.5
Resolution 2.75 Å R-free 0.259
7JYV Crystal Structure of HLA A*2402 in complex with YFSPIRVTF, an 9-mer influenza epitope Deposited 2020-09-01 Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein heterocomplex Heteromer；Protein × 3 PDB declaration: trimeric
Chain A 25–302（278 aa）
Not recorded MG MAGNESIUM ION × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 5.6；277 K；19% PEG 3350, 0.2 MgCl2
Resolution 1.51 Å R-free 0.206
7JYW Crystal Structure of HLA A*2402 in complex with TYQWIIRNW, an 9-mer influenza epitope Deposited 2020-09-01 Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein heterocomplex Heteromer；Protein × 3 PDB declaration: trimeric
Chain A 25–302（278 aa）
Not recorded CA CALCIUM ION × 1 NA SODIUM ION × 2 NI NICKEL (II) ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 5.6；277 K；20% PEG3350, 0.2M Na acetate
Resolution 2.90 Å R-free 0.275
7JYX Crystal Structure of HLA A*2402 in complex with TYQWIIRNWET, an 11-mer epitope from Influenza Deposited 2020-09-01 Different construct Different mutation/modification Different oligomeric state Different experimental conditions Different structure-quality metrics Assembly 1 Protein heterocomplex Heteromer；Protein × 3 PDB declaration: trimeric
Chain A 25–302（278 aa）
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 5.6；277 K；24% PEG8000, 0.1 HEPES pH 7.5, 5% v/v Ethyl acetate
Resolution 2.95 Å R-free 0.275
7JYX Crystal Structure of HLA A*2402 in complex with TYQWIIRNWET, an 11-mer epitope from Influenza Deposited 2020-09-01 Different construct Different mutation/modification Different oligomeric state Different experimental conditions Different structure-quality metrics Assembly 2 Protein heterocomplex Heteromer；Protein × 3 PDB declaration: trimeric
Chain D 25–302（278 aa）
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 5.6；277 K；24% PEG8000, 0.1 HEPES pH 7.5, 5% v/v Ethyl acetate
Resolution 2.95 Å R-free 0.275
7K80 KIR3DL1*001 in complex with HLA-A*24:02 presenting the RYPLTFGW peptide Deposited 2020-09-24 Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein heterocomplex Heteromer；Protein × 4 PDB declaration: tetrameric
Chain A 25–300（276 aa）
Not recorded FMT FORMIC ACID × 1 ACT ACETATE ION × 1 NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 3 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 5.6；298 K；14% PEG 3350, 2% tacsimate, pH 5.0, and 0.1 M trisodium citrate, pH 5.6
Resolution 2.40 Å R-free 0.249
7K80 KIR3DL1*001 in complex with HLA-A*24:02 presenting the RYPLTFGW peptide Deposited 2020-09-24 Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 2 Protein heterocomplex Heteromer；Protein × 4 PDB declaration: tetrameric
Chain D 25–300（276 aa）
Not recorded ACT ACETATE ION × 4 NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 5.6；298 K；14% PEG 3350, 2% tacsimate, pH 5.0, and 0.1 M trisodium citrate, pH 5.6
Resolution 2.40 Å R-free 0.249
7K81 KIR3DL1*005 in complex with HLA-A*24:02 presenting the RYPLTFGW peptide Deposited 2020-09-24 Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein heterocomplex Heteromer；Protein × 4 PDB declaration: tetrameric
Chain A 25–300（276 aa）
Not recorded NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 4 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 5.6；298 K；14% PEG 3350, 2% tacsimate, pH 5.0, and 0.1 M trisodium citrate, pH 5.6
Resolution 2.00 Å R-free 0.243
7NMD Human Major Histocompatibility Complex A24 Allele presenting QLPRLFPLL Deposited 2021-02-23 Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein heterocomplex Heteromer；Protein × 3 PDB declaration: trimeric
Chain A 25–300（276 aa）
Not recorded EDO 1,2-ETHANEDIOL × 4 PEG DI(HYDROXYETHYL)ETHER × 4 SO4 SULFATE ION × 4 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；291 K；20% PEG 4000, 0.1 M TRIS (pH 7.5), 15% glycerol.
Resolution 2.25 Å R-free 0.265
7NMD Human Major Histocompatibility Complex A24 Allele presenting QLPRLFPLL Deposited 2021-02-23 Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 2 Protein heterocomplex Heteromer；Protein × 3 PDB declaration: trimeric
Chain D 25–300（276 aa）
Not recorded EDO 1,2-ETHANEDIOL × 4 PEG DI(HYDROXYETHYL)ETHER × 2 SO4 SULFATE ION × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；291 K；20% PEG 4000, 0.1 M TRIS (pH 7.5), 15% glycerol.
Resolution 2.25 Å R-free 0.265
7NME Human MHC Class I, A24 Allele presenting QLPRLFPLL, Complex with 4C6 TCR Deposited 2021-02-23 Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein heterocomplex Heteromer；Protein × 5 PDB declaration: pentameric
Chain A 25–300（276 aa）
Not recorded BTB 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL × 1 SO4 SULFATE ION × 1 EDO 1,2-ETHANEDIOL × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 9；291 K；Molecular Dimensions Pact Premier C06: 0.1M PCTCP buffer, 25% PEG 1500, pH 9.0
Resolution 2.20 Å R-free 0.274
7NMF Human MHC Class I, A24 Allele presenting QLPRLFPLL, Complex with 4C6 TCR, monoclinic form Deposited 2021-02-23 Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein heterocomplex Heteromer；Protein × 5 PDB declaration: pentameric
Chain A 25–300（276 aa）
Not recorded MES 2-(N-MORPHOLINO)-ETHANESULFONIC ACID × 1 EDO 1,2-ETHANEDIOL × 1 SO4 SULFATE ION × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 7.5；291 K；0.1M Sodium Bromide, 0.1 M bis-tris Propane, pH 7.5, 20% PEG 3350
Resolution 2.98 Å R-free 0.259
7NMG Human MHC Class I, A24 Allele presenting LWM, Complex with 4C6 TCR Deposited 2021-02-23 Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein heterocomplex Heteromer；Protein × 5 PDB declaration: pentameric
Chain A 25–300（276 aa）
Not recorded SO4 SULFATE ION × 3 EPE 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID × 1 EDO 1,2-ETHANEDIOL × 3 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；291 K；25% PEG 1500, 0.1M PCTP Buffer, pH 9.0
Resolution 2.48 Å R-free 0.271
7WT3 Crystal structure of HLA-A*2402 complexed with 4-mer lipopeptide Deposited 2022-02-03 Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein heterocomplex Heteromer；Protein × 3 PDB declaration: trimeric
Chain A 24–300（277 aa）
Not recorded TRS 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL × 1 ACT ACETATE ION × 2 ZN ZINC ION × 2 EDO 1,2-ETHANEDIOL × 26 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 8；277 K；2mM ZnCL2, 100mM Tris, 20% PEG 6000
Resolution 1.89 Å R-free 0.235
7WT3 Crystal structure of HLA-A*2402 complexed with 4-mer lipopeptide Deposited 2022-02-03 Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 2 Protein heterocomplex Heteromer；Protein × 3 PDB declaration: trimeric
Chain D 24–300（277 aa）
Not recorded ACT ACETATE ION × 1 ZN ZINC ION × 1 EDO 1,2-ETHANEDIOL × 11 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 8；277 K；2mM ZnCL2, 100mM Tris, 20% PEG 6000
Resolution 1.89 Å R-free 0.235
7WT4 Crystal structure of HLA-A*2402 complexed with 8-mer Influenza PB1 peptide Deposited 2022-02-03 Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein heterocomplex Heteromer；Protein × 3 PDB declaration: trimeric
Chain A 24–300（277 aa）
Not recorded EDO 1,2-ETHANEDIOL × 33 ZN ZINC ION × 2 TRS 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL × 2 ACT ACETATE ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 7.8；293 K；100mM Tris, 20% PEG 6000
Resolution 1.89 Å R-free 0.232
7WT4 Crystal structure of HLA-A*2402 complexed with 8-mer Influenza PB1 peptide Deposited 2022-02-03 Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 2 Protein heterocomplex Heteromer；Protein × 3 PDB declaration: trimeric
Chain D 24–300（277 aa）
Not recorded EDO 1,2-ETHANEDIOL × 13 ZN ZINC ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 7.8；293 K；100mM Tris, 20% PEG 6000
Resolution 1.89 Å R-free 0.232
8RJH HLA A*2402-NF9_6F pMHC complex Deposited 2023-12-21 Different construct Different mutation/modification Different oligomeric state Different experimental conditions Different structure-quality metrics Assembly 1 Protein heterocomplex Heteromer；Protein × 3 PDB declaration: trimeric
Chain A 25–300（276 aa）
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；298 K；Glycerol 15% v/v Polyethylene Glycol 4,000, 20% w/v MES, 0.1 M, pH7
Resolution 2.60 Å R-free 0.264
8RJH HLA A*2402-NF9_6F pMHC complex Deposited 2023-12-21 Different construct Different mutation/modification Different oligomeric state Different experimental conditions Different structure-quality metrics Assembly 2 Protein heterocomplex Heteromer；Protein × 3 PDB declaration: trimeric
Chain D 25–300（276 aa）
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；298 K；Glycerol 15% v/v Polyethylene Glycol 4,000, 20% w/v MES, 0.1 M, pH7
Resolution 2.60 Å R-free 0.264
8RJH HLA A*2402-NF9_6F pMHC complex Deposited 2023-12-21 Different construct Different mutation/modification Different oligomeric state Different experimental conditions Different structure-quality metrics Assembly 3 Protein heterocomplex Heteromer；Protein × 3 PDB declaration: trimeric
Chain G 25–300（276 aa）
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；298 K；Glycerol 15% v/v Polyethylene Glycol 4,000, 20% w/v MES, 0.1 M, pH7
Resolution 2.60 Å R-free 0.264
8RJH HLA A*2402-NF9_6F pMHC complex Deposited 2023-12-21 Different construct Different mutation/modification Different oligomeric state Different experimental conditions Different structure-quality metrics Assembly 4 Protein heterocomplex Heteromer；Protein × 3 PDB declaration: trimeric
Chain J 25–300（276 aa）
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；298 K；Glycerol 15% v/v Polyethylene Glycol 4,000, 20% w/v MES, 0.1 M, pH7
Resolution 2.60 Å R-free 0.264
8RJH HLA A*2402-NF9_6F pMHC complex Deposited 2023-12-21 Different construct Different mutation/modification Different oligomeric state Different experimental conditions Different structure-quality metrics Assembly 5 Protein heterocomplex Heteromer；Protein × 3 PDB declaration: trimeric
Chain M 25–300（276 aa）
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；298 K；Glycerol 15% v/v Polyethylene Glycol 4,000, 20% w/v MES, 0.1 M, pH7
Resolution 2.60 Å R-free 0.264
8RJH HLA A*2402-NF9_6F pMHC complex Deposited 2023-12-21 Different construct Different mutation/modification Different oligomeric state Different experimental conditions Different structure-quality metrics Assembly 6 Protein heterocomplex Heteromer；Protein × 3 PDB declaration: trimeric
Chain P 25–300（276 aa）
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；298 K；Glycerol 15% v/v Polyethylene Glycol 4,000, 20% w/v MES, 0.1 M, pH7
Resolution 2.60 Å R-free 0.264
8RJI HLA A*2402-NF9_5R pMHC complex Deposited 2023-12-21 Different construct Different mutation/modification Different oligomeric state Different experimental conditions Different structure-quality metrics Assembly 1 Protein heterocomplex Heteromer；Protein × 3 PDB declaration: trimeric
Chain A 25–300（276 aa）
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；298 K；Glycerol 15% v/v Polyethylene glycol 4000, 20% w/v Sodium Cacodylate, 0.1 M, pH 6
Resolution 2.30 Å R-free 0.265
8RJI HLA A*2402-NF9_5R pMHC complex Deposited 2023-12-21 Different construct Different mutation/modification Different oligomeric state Different experimental conditions Different structure-quality metrics Assembly 2 Protein heterocomplex Heteromer；Protein × 3 PDB declaration: trimeric
Chain D 25–300（276 aa）
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；298 K；Glycerol 15% v/v Polyethylene glycol 4000, 20% w/v Sodium Cacodylate, 0.1 M, pH 6
Resolution 2.30 Å R-free 0.265
8RJI HLA A*2402-NF9_5R pMHC complex Deposited 2023-12-21 Different construct Different mutation/modification Different oligomeric state Different experimental conditions Different structure-quality metrics Assembly 3 Protein heterocomplex Heteromer；Protein × 3 PDB declaration: trimeric
Chain G 25–300（276 aa）
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；298 K；Glycerol 15% v/v Polyethylene glycol 4000, 20% w/v Sodium Cacodylate, 0.1 M, pH 6
Resolution 2.30 Å R-free 0.265
8RJI HLA A*2402-NF9_5R pMHC complex Deposited 2023-12-21 Different construct Different mutation/modification Different oligomeric state Different experimental conditions Different structure-quality metrics Assembly 4 Protein heterocomplex Heteromer；Protein × 3 PDB declaration: trimeric
Chain J 25–300（276 aa）
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；298 K；Glycerol 15% v/v Polyethylene glycol 4000, 20% w/v Sodium Cacodylate, 0.1 M, pH 6
Resolution 2.30 Å R-free 0.265
8SBK Structure of HLA-A*24:02 in complex with peptide, LYLPVRVLI (ATG2A). Deposited 2023-04-03 Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein heterocomplex Heteromer；Protein × 3 PDB declaration: trimeric
Chain A 25–304（280 aa）
Not recorded EDO 1,2-ETHANEDIOL × 2 SO4 SULFATE ION × 3 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 6.5；294 K；2 M Ammonium sulfate, 0.1 M Sodium cacodylate pH 6.5
Resolution 1.80 Å R-free 0.219
8SBL Structure of HLA-A*24:02 in complex with peptide, LYLPVRVLI Deposited 2023-04-03 Different construct Different mutation/modification Different oligomeric state Different experimental conditions Different structure-quality metrics Assembly 1 Protein heterocomplex Heteromer；Protein × 3 PDB declaration: trimeric
Chain A 25–304（280 aa）
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 6.5；294 K；0.05M MES monohydrate pH 6.5, 22.5% Polyethylene Glycol w/v 3350
Resolution 3.00 Å R-free 0.270
8SBL Structure of HLA-A*24:02 in complex with peptide, LYLPVRVLI Deposited 2023-04-03 Different construct Different mutation/modification Different oligomeric state Different experimental conditions Different structure-quality metrics Assembly 2 Protein heterocomplex Heteromer；Protein × 3 PDB declaration: trimeric
Chain D 25–304（280 aa）
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 6.5；294 K；0.05M MES monohydrate pH 6.5, 22.5% Polyethylene Glycol w/v 3350
Resolution 3.00 Å R-free 0.270
8SBL Structure of HLA-A*24:02 in complex with peptide, LYLPVRVLI Deposited 2023-04-03 Different construct Different mutation/modification Different oligomeric state Different experimental conditions Different structure-quality metrics Assembly 3 Protein heterocomplex Heteromer；Protein × 3 PDB declaration: trimeric
Chain G 25–304（280 aa）
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 6.5；294 K；0.05M MES monohydrate pH 6.5, 22.5% Polyethylene Glycol w/v 3350
Resolution 3.00 Å R-free 0.270
8SBL Structure of HLA-A*24:02 in complex with peptide, LYLPVRVLI Deposited 2023-04-03 Different construct Different mutation/modification Different oligomeric state Different experimental conditions Different structure-quality metrics Assembly 4 Protein heterocomplex Heteromer；Protein × 3 PDB declaration: trimeric
Chain J 25–304（280 aa）
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 6.5；294 K；0.05M MES monohydrate pH 6.5, 22.5% Polyethylene Glycol w/v 3350
Resolution 3.00 Å R-free 0.270
9BL5 KIR3DL1*001 in complex with HLA-A*24:02 presenting the TW9 peptide Deposited 2024-04-29 Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein heterocomplex Heteromer；Protein × 4 PDB declaration: tetrameric
Chain A 25–300（276 aa）
Not recorded NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 5.6；294 K；16% PEG-3350, 2% tacsimate pH 5.0, 0.1 M tri-sodium citrate pH 5.6
Resolution 2.00 Å R-free 0.231
9BL6 KIR3DL1*114 in complex with HLA-A*24:02 presenting the TW9 peptide Deposited 2024-04-29 Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein heterocomplex Heteromer；Protein × 4 PDB declaration: tetrameric
Chain A 25–300（276 aa）
Not recorded NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 5.6；294 K；14% PEG 3550, 2% tacsimate pH 5.0, 0.1 M tri-sodium citrate pH 5.6
Resolution 2.40 Å R-free 0.256
9BL9 KIR3DL1*114 in complex with HLA-A*24:02 presenting the NEF peptide Deposited 2024-04-29 Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein heterocomplex Heteromer；Protein × 4 PDB declaration: tetrameric
Chain A 25–300（276 aa）
Not recorded NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 5.6；294 K；14% PEG 3350, 2% tacsimate pH 5.0, 0.1 M tri-sodium citrate pH 5.6
Resolution 2.60 Å R-free 0.246
9BLA KIR3DL1*086 in complex with HLA-A*24:02 presenting the NEF peptide Deposited 2024-04-30 Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein heterocomplex Heteromer；Protein × 4 PDB declaration: tetrameric
Chain A 25–300（276 aa）
Not recorded NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 5.6；294 K；14% PEG 3350, 2% tacsimate pH 5.0, 0.1 M tri-sodium citrate pH 5.6
Resolution 3.00 Å R-free 0.248

24 other PDB entries and 42 assemblies. Open the comparison page and filter oligomeric states

View Construct and Data Evidence
UniProt name A0A411J078_HUMAN
Isoform —
PDB entities 1
Chains and sequence ranges Author chain A； PDBConstruct 143–417； UniProt 25–299 Author chain C； PDBConstruct 143–417； UniProt 25–299

RPA-related protein RADX peptide,Beta-2-microglobulin,MHC class I antigen chimera

Homo sapiens

UniProt P16213

State in the Current Structure

Assembly Oligomeric State Construct Mutations and Modifications Ligands, Ions and Associated Components Method and Experimental Conditions Structure Quality
1 Insufficient information Heteromer Protein × 2 PDB declaration: dimeric（2） Consistent with protein copy count Chain A； UniProt 21–119 Mutation：Y108C, A163C VHH × 1 X-RAY DIFFRACTION X-ray crystallization conditions：VAPOR DIFFUSION, HANGING DROP；295 K；100 mM MES, pH 6.0, 200 mM KSCN, 18% Peg 3350 Resolution 2.50 Å R-free 0.260
2 Insufficient information Heteromer Protein × 2 PDB declaration: dimeric（2） Consistent with protein copy count Chain C； UniProt 21–119 Mutation：Y108C, A163C VHH × 1 X-RAY DIFFRACTION X-ray crystallization conditions：VAPOR DIFFUSION, HANGING DROP；295 K；100 mM MES, pH 6.0, 200 mM KSCN, 18% Peg 3350 Resolution 2.50 Å R-free 0.260

Other States of the Same Protein in the Database

Each row is a biological assembly of the same UniProt protein in another PDB entry. The “Difference from current entry” column identifies evidence-level differences; no tag means the currently parsed fields agree.

Other PDB Difference from Current Entry 7SRK Assembly / Oligomeric State Construct Mutations and Modifications Ligands, Ions and Non-polymers Method and Experimental Conditions Structure Quality
7SQP Single chain trimer HLA-A*02:01 (Y108C) with HPV.16 E7 peptide YMLDLQPETTDL Deposited 2021-11-05 Different mutation/modification Different experimental conditions Different structure-quality metrics Assembly 1 Insufficient information Heteromer；Protein × 2 PDB declaration: dimeric
Chain A 21–119（99 aa）
Mutation：Y108C No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；295 K；200 mM NH4Citrate, 20.0% PEG 3350
Resolution 2.53 Å R-free 0.260
7SQP Single chain trimer HLA-A*02:01 (Y108C) with HPV.16 E7 peptide YMLDLQPETTDL Deposited 2021-11-05 Different mutation/modification Different experimental conditions Different structure-quality metrics Assembly 2 Insufficient information Heteromer；Protein × 2 PDB declaration: dimeric
Chain C 21–119（99 aa）
Mutation：Y108C No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；295 K；200 mM NH4Citrate, 20.0% PEG 3350
Resolution 2.53 Å R-free 0.260
7SR0 Single chain trimer HLA-A*02:01 (H98L, Y108C) with HPV.16 E7 peptide YMLDLQPET Deposited 2021-11-07 Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Insufficient information Heteromer；Protein × 2 PDB declaration: dimeric
Chain A 21–119（99 aa）
Mutation：H98L, Y108C PO4 PHOSPHATE ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；295 K；200 mM HK2PO4, 20% PEG 3350
Resolution 2.54 Å R-free 0.242
7SR0 Single chain trimer HLA-A*02:01 (H98L, Y108C) with HPV.16 E7 peptide YMLDLQPET Deposited 2021-11-07 Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 2 Insufficient information Heteromer；Protein × 2 PDB declaration: dimeric
Chain C 21–119（99 aa）
Mutation：H98L, Y108C PO4 PHOSPHATE ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；295 K；200 mM HK2PO4, 20% PEG 3350
Resolution 2.54 Å R-free 0.242
7SR3 Single chain trimer HLA-A*02:01 (H98L, Y108C) with HPV.16 E7 peptide YMLDLQPETTDL Deposited 2021-11-07 Different mutation/modification Different experimental conditions Different structure-quality metrics Assembly 1 Insufficient information Heteromer；Protein × 2 PDB declaration: dimeric
Chain A 21–119（99 aa）
Mutation：H98L, Y108C No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；295 K；200 mM K2SO4, 17% PEG 3350
Resolution 2.49 Å R-free 0.248
7SR3 Single chain trimer HLA-A*02:01 (H98L, Y108C) with HPV.16 E7 peptide YMLDLQPETTDL Deposited 2021-11-07 Different mutation/modification Different experimental conditions Different structure-quality metrics Assembly 2 Insufficient information Heteromer；Protein × 2 PDB declaration: dimeric
Chain C 21–119（99 aa）
Mutation：H98L, Y108C No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；295 K；200 mM K2SO4, 17% PEG 3350
Resolution 2.49 Å R-free 0.248
7SR4 Single chain trimer HLA-A*02:01 (H98L, Y108C) with HPV.16 E7 peptide YMLDLQPETTDLYC Deposited 2021-11-07 Different mutation/modification Different experimental conditions Different structure-quality metrics Assembly 1 Insufficient information Heteromer；Protein × 2 PDB declaration: dimeric
Chain A 21–119（99 aa）
Mutation：H98L, Y108C No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；295 K；100 mM KCitrate, pH 6.5, 17.5% PEG 3350
Resolution 2.59 Å R-free 0.247
7SR4 Single chain trimer HLA-A*02:01 (H98L, Y108C) with HPV.16 E7 peptide YMLDLQPETTDLYC Deposited 2021-11-07 Different mutation/modification Different experimental conditions Different structure-quality metrics Assembly 2 Insufficient information Heteromer；Protein × 2 PDB declaration: dimeric
Chain C 21–119（99 aa）
Mutation：H98L, Y108C No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；295 K；100 mM KCitrate, pH 6.5, 17.5% PEG 3350
Resolution 2.59 Å R-free 0.247
7SR5 Single chain trimer HLA-A*02:01 (Y108C, A163C) with Wilms tumor protein peptide RMFPNAPYL Deposited 2021-11-07 Different experimental conditions Different structure-quality metrics Assembly 1 Insufficient information Heteromer；Protein × 2 PDB declaration: dimeric
Chain A 21–119（99 aa）
Mutation：Y108C, A163C No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；295 K；200 mM NH4Citrate, 14.5% PEG 3350
Resolution 2.35 Å R-free 0.248
7SR5 Single chain trimer HLA-A*02:01 (Y108C, A163C) with Wilms tumor protein peptide RMFPNAPYL Deposited 2021-11-07 Different experimental conditions Different structure-quality metrics Assembly 2 Insufficient information Heteromer；Protein × 2 PDB declaration: dimeric
Chain C 21–119（99 aa）
Mutation：Y108C, A163C No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；295 K；200 mM NH4Citrate, 14.5% PEG 3350
Resolution 2.35 Å R-free 0.248
7SSH Single chain trimer HLA-A*02:01 (Y108A) with HPV.16 E7 peptide YMLDLQPETTDLYC Deposited 2021-11-11 Different mutation/modification Different experimental conditions Different structure-quality metrics Assembly 1 Insufficient information Heteromer；Protein × 2 PDB declaration: dimeric
Chain A 21–119（99 aa）
Mutation：Y108A No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；295 K；200 mM NaCl, 100 mM HEPES, pH 7.0, 1.45 M (NH4)2SO4
Resolution 2.73 Å R-free 0.294
7SSH Single chain trimer HLA-A*02:01 (Y108A) with HPV.16 E7 peptide YMLDLQPETTDLYC Deposited 2021-11-11 Different mutation/modification Different experimental conditions Different structure-quality metrics Assembly 10 Insufficient information Heteromer；Protein × 2 PDB declaration: dimeric
Chain S 21–119（99 aa）
Mutation：Y108A No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；295 K；200 mM NaCl, 100 mM HEPES, pH 7.0, 1.45 M (NH4)2SO4
Resolution 2.73 Å R-free 0.294
7SSH Single chain trimer HLA-A*02:01 (Y108A) with HPV.16 E7 peptide YMLDLQPETTDLYC Deposited 2021-11-11 Different mutation/modification Different experimental conditions Different structure-quality metrics Assembly 11 Insufficient information Heteromer；Protein × 2 PDB declaration: dimeric
Chain U 21–119（99 aa）
Mutation：Y108A No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；295 K；200 mM NaCl, 100 mM HEPES, pH 7.0, 1.45 M (NH4)2SO4
Resolution 2.73 Å R-free 0.294
7SSH Single chain trimer HLA-A*02:01 (Y108A) with HPV.16 E7 peptide YMLDLQPETTDLYC Deposited 2021-11-11 Different mutation/modification Different experimental conditions Different structure-quality metrics Assembly 12 Insufficient information Heteromer；Protein × 2 PDB declaration: dimeric
Chain W 21–119（99 aa）
Mutation：Y108A No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；295 K；200 mM NaCl, 100 mM HEPES, pH 7.0, 1.45 M (NH4)2SO4
Resolution 2.73 Å R-free 0.294
7SSH Single chain trimer HLA-A*02:01 (Y108A) with HPV.16 E7 peptide YMLDLQPETTDLYC Deposited 2021-11-11 Different mutation/modification Different experimental conditions Different structure-quality metrics Assembly 13 Insufficient information Heteromer；Protein × 2 PDB declaration: dimeric
Chain Y 21–119（99 aa）
Mutation：Y108A No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；295 K；200 mM NaCl, 100 mM HEPES, pH 7.0, 1.45 M (NH4)2SO4
Resolution 2.73 Å R-free 0.294
7SSH Single chain trimer HLA-A*02:01 (Y108A) with HPV.16 E7 peptide YMLDLQPETTDLYC Deposited 2021-11-11 Different mutation/modification Different experimental conditions Different structure-quality metrics Assembly 14 Insufficient information Heteromer；Protein × 2 PDB declaration: dimeric
Chain a 21–119（99 aa）
Mutation：Y108A No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；295 K；200 mM NaCl, 100 mM HEPES, pH 7.0, 1.45 M (NH4)2SO4
Resolution 2.73 Å R-free 0.294
7SSH Single chain trimer HLA-A*02:01 (Y108A) with HPV.16 E7 peptide YMLDLQPETTDLYC Deposited 2021-11-11 Different mutation/modification Different experimental conditions Different structure-quality metrics Assembly 15 Insufficient information Heteromer；Protein × 2 PDB declaration: dimeric
Chain c 21–119（99 aa）
Mutation：Y108A No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；295 K；200 mM NaCl, 100 mM HEPES, pH 7.0, 1.45 M (NH4)2SO4
Resolution 2.73 Å R-free 0.294
7SSH Single chain trimer HLA-A*02:01 (Y108A) with HPV.16 E7 peptide YMLDLQPETTDLYC Deposited 2021-11-11 Different mutation/modification Different experimental conditions Different structure-quality metrics Assembly 16 Insufficient information Heteromer；Protein × 2 PDB declaration: dimeric
Chain e 21–119（99 aa）
Mutation：Y108A No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；295 K；200 mM NaCl, 100 mM HEPES, pH 7.0, 1.45 M (NH4)2SO4
Resolution 2.73 Å R-free 0.294
7SSH Single chain trimer HLA-A*02:01 (Y108A) with HPV.16 E7 peptide YMLDLQPETTDLYC Deposited 2021-11-11 Different mutation/modification Different experimental conditions Different structure-quality metrics Assembly 2 Insufficient information Heteromer；Protein × 2 PDB declaration: dimeric
Chain C 21–119（99 aa）
Mutation：Y108A No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；295 K；200 mM NaCl, 100 mM HEPES, pH 7.0, 1.45 M (NH4)2SO4
Resolution 2.73 Å R-free 0.294
7SSH Single chain trimer HLA-A*02:01 (Y108A) with HPV.16 E7 peptide YMLDLQPETTDLYC Deposited 2021-11-11 Different mutation/modification Different experimental conditions Different structure-quality metrics Assembly 3 Insufficient information Heteromer；Protein × 2 PDB declaration: dimeric
Chain E 21–119（99 aa）
Mutation：Y108A No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；295 K；200 mM NaCl, 100 mM HEPES, pH 7.0, 1.45 M (NH4)2SO4
Resolution 2.73 Å R-free 0.294
7SSH Single chain trimer HLA-A*02:01 (Y108A) with HPV.16 E7 peptide YMLDLQPETTDLYC Deposited 2021-11-11 Different mutation/modification Different experimental conditions Different structure-quality metrics Assembly 4 Insufficient information Heteromer；Protein × 2 PDB declaration: dimeric
Chain G 21–119（99 aa）
Mutation：Y108A No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；295 K；200 mM NaCl, 100 mM HEPES, pH 7.0, 1.45 M (NH4)2SO4
Resolution 2.73 Å R-free 0.294
7SSH Single chain trimer HLA-A*02:01 (Y108A) with HPV.16 E7 peptide YMLDLQPETTDLYC Deposited 2021-11-11 Different mutation/modification Different experimental conditions Different structure-quality metrics Assembly 5 Insufficient information Heteromer；Protein × 2 PDB declaration: dimeric
Chain I 21–119（99 aa）
Mutation：Y108A No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；295 K；200 mM NaCl, 100 mM HEPES, pH 7.0, 1.45 M (NH4)2SO4
Resolution 2.73 Å R-free 0.294
7SSH Single chain trimer HLA-A*02:01 (Y108A) with HPV.16 E7 peptide YMLDLQPETTDLYC Deposited 2021-11-11 Different mutation/modification Different experimental conditions Different structure-quality metrics Assembly 6 Insufficient information Heteromer；Protein × 2 PDB declaration: dimeric
Chain K 21–119（99 aa）
Mutation：Y108A No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；295 K；200 mM NaCl, 100 mM HEPES, pH 7.0, 1.45 M (NH4)2SO4
Resolution 2.73 Å R-free 0.294
7SSH Single chain trimer HLA-A*02:01 (Y108A) with HPV.16 E7 peptide YMLDLQPETTDLYC Deposited 2021-11-11 Different mutation/modification Different experimental conditions Different structure-quality metrics Assembly 7 Insufficient information Heteromer；Protein × 2 PDB declaration: dimeric
Chain M 21–119（99 aa）
Mutation：Y108A No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；295 K；200 mM NaCl, 100 mM HEPES, pH 7.0, 1.45 M (NH4)2SO4
Resolution 2.73 Å R-free 0.294
7SSH Single chain trimer HLA-A*02:01 (Y108A) with HPV.16 E7 peptide YMLDLQPETTDLYC Deposited 2021-11-11 Different mutation/modification Different experimental conditions Different structure-quality metrics Assembly 8 Insufficient information Heteromer；Protein × 2 PDB declaration: dimeric
Chain O 21–119（99 aa）
Mutation：Y108A No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；295 K；200 mM NaCl, 100 mM HEPES, pH 7.0, 1.45 M (NH4)2SO4
Resolution 2.73 Å R-free 0.294
7SSH Single chain trimer HLA-A*02:01 (Y108A) with HPV.16 E7 peptide YMLDLQPETTDLYC Deposited 2021-11-11 Different mutation/modification Different experimental conditions Different structure-quality metrics Assembly 9 Insufficient information Heteromer；Protein × 2 PDB declaration: dimeric
Chain Q 21–119（99 aa）
Mutation：Y108A No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；295 K；200 mM NaCl, 100 mM HEPES, pH 7.0, 1.45 M (NH4)2SO4
Resolution 2.73 Å R-free 0.294
7ST3 Consequences of HLA single chain trimer mutations on peptide presentation and binding affinity Deposited 2021-11-11 Different mutation/modification Different experimental conditions Different structure-quality metrics Assembly 1 Insufficient information Heteromer；Protein × 2 PDB declaration: dimeric
Chain A 21–119（99 aa）
Mutation：Y108C,A163C No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；295 K；100 mM Tris, pH 7.5, 200 mM Li2SO4, 1.6 M AmSO4
Resolution 2.78 Å R-free 0.275
7ST3 Consequences of HLA single chain trimer mutations on peptide presentation and binding affinity Deposited 2021-11-11 Different mutation/modification Different experimental conditions Different structure-quality metrics Assembly 10 Insufficient information Heteromer；Protein × 2 PDB declaration: dimeric
Chain S 21–119（99 aa）
Mutation：Y108C,A163C No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；295 K；100 mM Tris, pH 7.5, 200 mM Li2SO4, 1.6 M AmSO4
Resolution 2.78 Å R-free 0.275
7ST3 Consequences of HLA single chain trimer mutations on peptide presentation and binding affinity Deposited 2021-11-11 Different mutation/modification Different experimental conditions Different structure-quality metrics Assembly 11 Insufficient information Heteromer；Protein × 2 PDB declaration: dimeric
Chain U 21–119（99 aa）
Mutation：Y108C,A163C No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；295 K；100 mM Tris, pH 7.5, 200 mM Li2SO4, 1.6 M AmSO4
Resolution 2.78 Å R-free 0.275
7ST3 Consequences of HLA single chain trimer mutations on peptide presentation and binding affinity Deposited 2021-11-11 Different mutation/modification Different experimental conditions Different structure-quality metrics Assembly 12 Insufficient information Heteromer；Protein × 2 PDB declaration: dimeric
Chain W 21–119（99 aa）
Mutation：Y108C,A163C No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；295 K；100 mM Tris, pH 7.5, 200 mM Li2SO4, 1.6 M AmSO4
Resolution 2.78 Å R-free 0.275
7ST3 Consequences of HLA single chain trimer mutations on peptide presentation and binding affinity Deposited 2021-11-11 Different mutation/modification Different experimental conditions Different structure-quality metrics Assembly 13 Insufficient information Heteromer；Protein × 2 PDB declaration: dimeric
Chain Y 21–119（99 aa）
Mutation：Y108C,A163C No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；295 K；100 mM Tris, pH 7.5, 200 mM Li2SO4, 1.6 M AmSO4
Resolution 2.78 Å R-free 0.275
7ST3 Consequences of HLA single chain trimer mutations on peptide presentation and binding affinity Deposited 2021-11-11 Different mutation/modification Different experimental conditions Different structure-quality metrics Assembly 14 Insufficient information Heteromer；Protein × 2 PDB declaration: dimeric
Chain a 21–119（99 aa）
Mutation：Y108C,A163C No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；295 K；100 mM Tris, pH 7.5, 200 mM Li2SO4, 1.6 M AmSO4
Resolution 2.78 Å R-free 0.275
7ST3 Consequences of HLA single chain trimer mutations on peptide presentation and binding affinity Deposited 2021-11-11 Different mutation/modification Different experimental conditions Different structure-quality metrics Assembly 15 Insufficient information Heteromer；Protein × 2 PDB declaration: dimeric
Chain c 21–119（99 aa）
Mutation：Y108C,A163C No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；295 K；100 mM Tris, pH 7.5, 200 mM Li2SO4, 1.6 M AmSO4
Resolution 2.78 Å R-free 0.275
7ST3 Consequences of HLA single chain trimer mutations on peptide presentation and binding affinity Deposited 2021-11-11 Different mutation/modification Different experimental conditions Different structure-quality metrics Assembly 16 Insufficient information Heteromer；Protein × 2 PDB declaration: dimeric
Chain e 21–119（99 aa）
Mutation：Y108C,A163C No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；295 K；100 mM Tris, pH 7.5, 200 mM Li2SO4, 1.6 M AmSO4
Resolution 2.78 Å R-free 0.275
7ST3 Consequences of HLA single chain trimer mutations on peptide presentation and binding affinity Deposited 2021-11-11 Different mutation/modification Different experimental conditions Different structure-quality metrics Assembly 2 Insufficient information Heteromer；Protein × 2 PDB declaration: dimeric
Chain C 21–119（99 aa）
Mutation：Y108C,A163C No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；295 K；100 mM Tris, pH 7.5, 200 mM Li2SO4, 1.6 M AmSO4
Resolution 2.78 Å R-free 0.275
7ST3 Consequences of HLA single chain trimer mutations on peptide presentation and binding affinity Deposited 2021-11-11 Different mutation/modification Different experimental conditions Different structure-quality metrics Assembly 3 Insufficient information Heteromer；Protein × 2 PDB declaration: dimeric
Chain E 21–119（99 aa）
Mutation：Y108C,A163C No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；295 K；100 mM Tris, pH 7.5, 200 mM Li2SO4, 1.6 M AmSO4
Resolution 2.78 Å R-free 0.275
7ST3 Consequences of HLA single chain trimer mutations on peptide presentation and binding affinity Deposited 2021-11-11 Different mutation/modification Different experimental conditions Different structure-quality metrics Assembly 4 Insufficient information Heteromer；Protein × 2 PDB declaration: dimeric
Chain G 21–119（99 aa）
Mutation：Y108C,A163C No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；295 K；100 mM Tris, pH 7.5, 200 mM Li2SO4, 1.6 M AmSO4
Resolution 2.78 Å R-free 0.275
7ST3 Consequences of HLA single chain trimer mutations on peptide presentation and binding affinity Deposited 2021-11-11 Different mutation/modification Different experimental conditions Different structure-quality metrics Assembly 5 Insufficient information Heteromer；Protein × 2 PDB declaration: dimeric
Chain I 21–119（99 aa）
Mutation：Y108C,A163C No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；295 K；100 mM Tris, pH 7.5, 200 mM Li2SO4, 1.6 M AmSO4
Resolution 2.78 Å R-free 0.275
7ST3 Consequences of HLA single chain trimer mutations on peptide presentation and binding affinity Deposited 2021-11-11 Different mutation/modification Different experimental conditions Different structure-quality metrics Assembly 6 Insufficient information Heteromer；Protein × 2 PDB declaration: dimeric
Chain K 21–119（99 aa）
Mutation：Y108C,A163C No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；295 K；100 mM Tris, pH 7.5, 200 mM Li2SO4, 1.6 M AmSO4
Resolution 2.78 Å R-free 0.275
7ST3 Consequences of HLA single chain trimer mutations on peptide presentation and binding affinity Deposited 2021-11-11 Different mutation/modification Different experimental conditions Different structure-quality metrics Assembly 7 Insufficient information Heteromer；Protein × 2 PDB declaration: dimeric
Chain M 21–119（99 aa）
Mutation：Y108C,A163C No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；295 K；100 mM Tris, pH 7.5, 200 mM Li2SO4, 1.6 M AmSO4
Resolution 2.78 Å R-free 0.275
7ST3 Consequences of HLA single chain trimer mutations on peptide presentation and binding affinity Deposited 2021-11-11 Different mutation/modification Different experimental conditions Different structure-quality metrics Assembly 8 Insufficient information Heteromer；Protein × 2 PDB declaration: dimeric
Chain O 21–119（99 aa）
Mutation：Y108C,A163C No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；295 K；100 mM Tris, pH 7.5, 200 mM Li2SO4, 1.6 M AmSO4
Resolution 2.78 Å R-free 0.275
7ST3 Consequences of HLA single chain trimer mutations on peptide presentation and binding affinity Deposited 2021-11-11 Different mutation/modification Different experimental conditions Different structure-quality metrics Assembly 9 Insufficient information Heteromer；Protein × 2 PDB declaration: dimeric
Chain Q 21–119（99 aa）
Mutation：Y108C,A163C No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；295 K；100 mM Tris, pH 7.5, 200 mM Li2SO4, 1.6 M AmSO4
Resolution 2.78 Å R-free 0.275
7STG Consequences of HLA single chain trimer mutations on peptide presentation and binding affinity Deposited 2021-11-12 Different experimental conditions Different structure-quality metrics Assembly 1 Insufficient information Heteromer；Protein × 2 PDB declaration: dimeric
Chain A 21–119（99 aa）
Mutation：Y108C, A163C No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；295 K；100 mM Tris, pH 8.0, 200 mM Li2SO4, 1.1 M AmSO4
Resolution 2.70 Å R-free 0.276
7STG Consequences of HLA single chain trimer mutations on peptide presentation and binding affinity Deposited 2021-11-12 Different experimental conditions Different structure-quality metrics Assembly 10 Insufficient information Heteromer；Protein × 2 PDB declaration: dimeric
Chain S 21–119（99 aa）
Mutation：Y108C, A163C No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；295 K；100 mM Tris, pH 8.0, 200 mM Li2SO4, 1.1 M AmSO4
Resolution 2.70 Å R-free 0.276
7STG Consequences of HLA single chain trimer mutations on peptide presentation and binding affinity Deposited 2021-11-12 Different experimental conditions Different structure-quality metrics Assembly 11 Insufficient information Heteromer；Protein × 2 PDB declaration: dimeric
Chain U 21–119（99 aa）
Mutation：Y108C, A163C No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；295 K；100 mM Tris, pH 8.0, 200 mM Li2SO4, 1.1 M AmSO4
Resolution 2.70 Å R-free 0.276
7STG Consequences of HLA single chain trimer mutations on peptide presentation and binding affinity Deposited 2021-11-12 Different experimental conditions Different structure-quality metrics Assembly 12 Insufficient information Heteromer；Protein × 2 PDB declaration: dimeric
Chain W 21–119（99 aa）
Mutation：Y108C, A163C No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；295 K；100 mM Tris, pH 8.0, 200 mM Li2SO4, 1.1 M AmSO4
Resolution 2.70 Å R-free 0.276
7STG Consequences of HLA single chain trimer mutations on peptide presentation and binding affinity Deposited 2021-11-12 Different experimental conditions Different structure-quality metrics Assembly 13 Insufficient information Heteromer；Protein × 2 PDB declaration: dimeric
Chain Y 21–119（99 aa）
Mutation：Y108C, A163C No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；295 K；100 mM Tris, pH 8.0, 200 mM Li2SO4, 1.1 M AmSO4
Resolution 2.70 Å R-free 0.276
7STG Consequences of HLA single chain trimer mutations on peptide presentation and binding affinity Deposited 2021-11-12 Different experimental conditions Different structure-quality metrics Assembly 14 Insufficient information Heteromer；Protein × 2 PDB declaration: dimeric
Chain a 21–119（99 aa）
Mutation：Y108C, A163C No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；295 K；100 mM Tris, pH 8.0, 200 mM Li2SO4, 1.1 M AmSO4
Resolution 2.70 Å R-free 0.276
7STG Consequences of HLA single chain trimer mutations on peptide presentation and binding affinity Deposited 2021-11-12 Different experimental conditions Different structure-quality metrics Assembly 15 Insufficient information Heteromer；Protein × 2 PDB declaration: dimeric
Chain c 21–119（99 aa）
Mutation：Y108C, A163C No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；295 K；100 mM Tris, pH 8.0, 200 mM Li2SO4, 1.1 M AmSO4
Resolution 2.70 Å R-free 0.276
7STG Consequences of HLA single chain trimer mutations on peptide presentation and binding affinity Deposited 2021-11-12 Different experimental conditions Different structure-quality metrics Assembly 16 Insufficient information Heteromer；Protein × 2 PDB declaration: dimeric
Chain e 21–119（99 aa）
Mutation：Y108C, A163C No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；295 K；100 mM Tris, pH 8.0, 200 mM Li2SO4, 1.1 M AmSO4
Resolution 2.70 Å R-free 0.276
7STG Consequences of HLA single chain trimer mutations on peptide presentation and binding affinity Deposited 2021-11-12 Different experimental conditions Different structure-quality metrics Assembly 2 Insufficient information Heteromer；Protein × 2 PDB declaration: dimeric
Chain C 21–119（99 aa）
Mutation：Y108C, A163C No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；295 K；100 mM Tris, pH 8.0, 200 mM Li2SO4, 1.1 M AmSO4
Resolution 2.70 Å R-free 0.276
7STG Consequences of HLA single chain trimer mutations on peptide presentation and binding affinity Deposited 2021-11-12 Different experimental conditions Different structure-quality metrics Assembly 3 Insufficient information Heteromer；Protein × 2 PDB declaration: dimeric
Chain E 21–119（99 aa）
Mutation：Y108C, A163C No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；295 K；100 mM Tris, pH 8.0, 200 mM Li2SO4, 1.1 M AmSO4
Resolution 2.70 Å R-free 0.276
7STG Consequences of HLA single chain trimer mutations on peptide presentation and binding affinity Deposited 2021-11-12 Different experimental conditions Different structure-quality metrics Assembly 4 Insufficient information Heteromer；Protein × 2 PDB declaration: dimeric
Chain G 21–119（99 aa）
Mutation：Y108C, A163C No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；295 K；100 mM Tris, pH 8.0, 200 mM Li2SO4, 1.1 M AmSO4
Resolution 2.70 Å R-free 0.276
7STG Consequences of HLA single chain trimer mutations on peptide presentation and binding affinity Deposited 2021-11-12 Different experimental conditions Different structure-quality metrics Assembly 5 Insufficient information Heteromer；Protein × 2 PDB declaration: dimeric
Chain I 21–119（99 aa）
Mutation：Y108C, A163C No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；295 K；100 mM Tris, pH 8.0, 200 mM Li2SO4, 1.1 M AmSO4
Resolution 2.70 Å R-free 0.276
7STG Consequences of HLA single chain trimer mutations on peptide presentation and binding affinity Deposited 2021-11-12 Different experimental conditions Different structure-quality metrics Assembly 6 Insufficient information Heteromer；Protein × 2 PDB declaration: dimeric
Chain K 21–119（99 aa）
Mutation：Y108C, A163C No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；295 K；100 mM Tris, pH 8.0, 200 mM Li2SO4, 1.1 M AmSO4
Resolution 2.70 Å R-free 0.276
7STG Consequences of HLA single chain trimer mutations on peptide presentation and binding affinity Deposited 2021-11-12 Different experimental conditions Different structure-quality metrics Assembly 7 Insufficient information Heteromer；Protein × 2 PDB declaration: dimeric
Chain M 21–119（99 aa）
Mutation：Y108C, A163C No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；295 K；100 mM Tris, pH 8.0, 200 mM Li2SO4, 1.1 M AmSO4
Resolution 2.70 Å R-free 0.276
7STG Consequences of HLA single chain trimer mutations on peptide presentation and binding affinity Deposited 2021-11-12 Different experimental conditions Different structure-quality metrics Assembly 8 Insufficient information Heteromer；Protein × 2 PDB declaration: dimeric
Chain O 21–119（99 aa）
Mutation：Y108C, A163C No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；295 K；100 mM Tris, pH 8.0, 200 mM Li2SO4, 1.1 M AmSO4
Resolution 2.70 Å R-free 0.276
7STG Consequences of HLA single chain trimer mutations on peptide presentation and binding affinity Deposited 2021-11-12 Different experimental conditions Different structure-quality metrics Assembly 9 Insufficient information Heteromer；Protein × 2 PDB declaration: dimeric
Chain Q 21–119（99 aa）
Mutation：Y108C, A163C No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；295 K；100 mM Tris, pH 8.0, 200 mM Li2SO4, 1.1 M AmSO4
Resolution 2.70 Å R-free 0.276

8 other PDB entries and 58 assemblies. Open the comparison page and filter oligomeric states

View Construct and Data Evidence
UniProt name B2MG_PONPY
Isoform —
PDB entities 1
Chains and sequence ranges Author chain A； PDBConstruct 24–122； UniProt 21–119 Author chain C； PDBConstruct 24–122； UniProt 21–119

RPA-related protein RADX peptide,Beta-2-microglobulin,MHC class I antigen chimera

Homo sapiens

UniProt Q6NSI4

State in the Current Structure

Assembly Oligomeric State Construct Mutations and Modifications Ligands, Ions and Associated Components Method and Experimental Conditions Structure Quality
1 Insufficient information Heteromer Protein × 2 PDB declaration: dimeric（2） Consistent with protein copy count Chain A； UniProt 509–516 Mutation：Y108C, A163C VHH × 1 X-RAY DIFFRACTION X-ray crystallization conditions：VAPOR DIFFUSION, HANGING DROP；295 K；100 mM MES, pH 6.0, 200 mM KSCN, 18% Peg 3350 Resolution 2.50 Å R-free 0.260
2 Insufficient information Heteromer Protein × 2 PDB declaration: dimeric（2） Consistent with protein copy count Chain C； UniProt 509–516 Mutation：Y108C, A163C VHH × 1 X-RAY DIFFRACTION X-ray crystallization conditions：VAPOR DIFFUSION, HANGING DROP；295 K；100 mM MES, pH 6.0, 200 mM KSCN, 18% Peg 3350 Resolution 2.50 Å R-free 0.260

Other States of the Same Protein in the Database

Each row is a biological assembly of the same UniProt protein in another PDB entry. The “Difference from current entry” column identifies evidence-level differences; no tag means the currently parsed fields agree.

Other PDB Difference from Current Entry 7SRK Assembly / Oligomeric State Construct Mutations and Modifications Ligands, Ions and Non-polymers Method and Experimental Conditions Structure Quality
7STG Consequences of HLA single chain trimer mutations on peptide presentation and binding affinity Deposited 2021-11-12 Different experimental conditions Different structure-quality metrics Assembly 1 Insufficient information Heteromer；Protein × 2 PDB declaration: dimeric
Chain A 509–516（8 aa）
Mutation：Y108C, A163C No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；295 K；100 mM Tris, pH 8.0, 200 mM Li2SO4, 1.1 M AmSO4
Resolution 2.70 Å R-free 0.276
7STG Consequences of HLA single chain trimer mutations on peptide presentation and binding affinity Deposited 2021-11-12 Different experimental conditions Different structure-quality metrics Assembly 10 Insufficient information Heteromer；Protein × 2 PDB declaration: dimeric
Chain S 509–516（8 aa）
Mutation：Y108C, A163C No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；295 K；100 mM Tris, pH 8.0, 200 mM Li2SO4, 1.1 M AmSO4
Resolution 2.70 Å R-free 0.276
7STG Consequences of HLA single chain trimer mutations on peptide presentation and binding affinity Deposited 2021-11-12 Different experimental conditions Different structure-quality metrics Assembly 11 Insufficient information Heteromer；Protein × 2 PDB declaration: dimeric
Chain U 509–516（8 aa）
Mutation：Y108C, A163C No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；295 K；100 mM Tris, pH 8.0, 200 mM Li2SO4, 1.1 M AmSO4
Resolution 2.70 Å R-free 0.276
7STG Consequences of HLA single chain trimer mutations on peptide presentation and binding affinity Deposited 2021-11-12 Different experimental conditions Different structure-quality metrics Assembly 12 Insufficient information Heteromer；Protein × 2 PDB declaration: dimeric
Chain W 509–516（8 aa）
Mutation：Y108C, A163C No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；295 K；100 mM Tris, pH 8.0, 200 mM Li2SO4, 1.1 M AmSO4
Resolution 2.70 Å R-free 0.276
7STG Consequences of HLA single chain trimer mutations on peptide presentation and binding affinity Deposited 2021-11-12 Different experimental conditions Different structure-quality metrics Assembly 13 Insufficient information Heteromer；Protein × 2 PDB declaration: dimeric
Chain Y 509–516（8 aa）
Mutation：Y108C, A163C No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；295 K；100 mM Tris, pH 8.0, 200 mM Li2SO4, 1.1 M AmSO4
Resolution 2.70 Å R-free 0.276
7STG Consequences of HLA single chain trimer mutations on peptide presentation and binding affinity Deposited 2021-11-12 Different experimental conditions Different structure-quality metrics Assembly 14 Insufficient information Heteromer；Protein × 2 PDB declaration: dimeric
Chain a 509–516（8 aa）
Mutation：Y108C, A163C No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；295 K；100 mM Tris, pH 8.0, 200 mM Li2SO4, 1.1 M AmSO4
Resolution 2.70 Å R-free 0.276
7STG Consequences of HLA single chain trimer mutations on peptide presentation and binding affinity Deposited 2021-11-12 Different experimental conditions Different structure-quality metrics Assembly 15 Insufficient information Heteromer；Protein × 2 PDB declaration: dimeric
Chain c 509–516（8 aa）
Mutation：Y108C, A163C No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；295 K；100 mM Tris, pH 8.0, 200 mM Li2SO4, 1.1 M AmSO4
Resolution 2.70 Å R-free 0.276
7STG Consequences of HLA single chain trimer mutations on peptide presentation and binding affinity Deposited 2021-11-12 Different experimental conditions Different structure-quality metrics Assembly 16 Insufficient information Heteromer；Protein × 2 PDB declaration: dimeric
Chain e 509–516（8 aa）
Mutation：Y108C, A163C No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；295 K；100 mM Tris, pH 8.0, 200 mM Li2SO4, 1.1 M AmSO4
Resolution 2.70 Å R-free 0.276
7STG Consequences of HLA single chain trimer mutations on peptide presentation and binding affinity Deposited 2021-11-12 Different experimental conditions Different structure-quality metrics Assembly 2 Insufficient information Heteromer；Protein × 2 PDB declaration: dimeric
Chain C 509–516（8 aa）
Mutation：Y108C, A163C No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；295 K；100 mM Tris, pH 8.0, 200 mM Li2SO4, 1.1 M AmSO4
Resolution 2.70 Å R-free 0.276
7STG Consequences of HLA single chain trimer mutations on peptide presentation and binding affinity Deposited 2021-11-12 Different experimental conditions Different structure-quality metrics Assembly 3 Insufficient information Heteromer；Protein × 2 PDB declaration: dimeric
Chain E 509–516（8 aa）
Mutation：Y108C, A163C No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；295 K；100 mM Tris, pH 8.0, 200 mM Li2SO4, 1.1 M AmSO4
Resolution 2.70 Å R-free 0.276
7STG Consequences of HLA single chain trimer mutations on peptide presentation and binding affinity Deposited 2021-11-12 Different experimental conditions Different structure-quality metrics Assembly 4 Insufficient information Heteromer；Protein × 2 PDB declaration: dimeric
Chain G 509–516（8 aa）
Mutation：Y108C, A163C No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；295 K；100 mM Tris, pH 8.0, 200 mM Li2SO4, 1.1 M AmSO4
Resolution 2.70 Å R-free 0.276
7STG Consequences of HLA single chain trimer mutations on peptide presentation and binding affinity Deposited 2021-11-12 Different experimental conditions Different structure-quality metrics Assembly 5 Insufficient information Heteromer；Protein × 2 PDB declaration: dimeric
Chain I 509–516（8 aa）
Mutation：Y108C, A163C No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；295 K；100 mM Tris, pH 8.0, 200 mM Li2SO4, 1.1 M AmSO4
Resolution 2.70 Å R-free 0.276
7STG Consequences of HLA single chain trimer mutations on peptide presentation and binding affinity Deposited 2021-11-12 Different experimental conditions Different structure-quality metrics Assembly 6 Insufficient information Heteromer；Protein × 2 PDB declaration: dimeric
Chain K 509–516（8 aa）
Mutation：Y108C, A163C No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；295 K；100 mM Tris, pH 8.0, 200 mM Li2SO4, 1.1 M AmSO4
Resolution 2.70 Å R-free 0.276
7STG Consequences of HLA single chain trimer mutations on peptide presentation and binding affinity Deposited 2021-11-12 Different experimental conditions Different structure-quality metrics Assembly 7 Insufficient information Heteromer；Protein × 2 PDB declaration: dimeric
Chain M 509–516（8 aa）
Mutation：Y108C, A163C No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；295 K；100 mM Tris, pH 8.0, 200 mM Li2SO4, 1.1 M AmSO4
Resolution 2.70 Å R-free 0.276
7STG Consequences of HLA single chain trimer mutations on peptide presentation and binding affinity Deposited 2021-11-12 Different experimental conditions Different structure-quality metrics Assembly 8 Insufficient information Heteromer；Protein × 2 PDB declaration: dimeric
Chain O 509–516（8 aa）
Mutation：Y108C, A163C No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；295 K；100 mM Tris, pH 8.0, 200 mM Li2SO4, 1.1 M AmSO4
Resolution 2.70 Å R-free 0.276
7STG Consequences of HLA single chain trimer mutations on peptide presentation and binding affinity Deposited 2021-11-12 Different experimental conditions Different structure-quality metrics Assembly 9 Insufficient information Heteromer；Protein × 2 PDB declaration: dimeric
Chain Q 509–516（8 aa）
Mutation：Y108C, A163C No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；295 K；100 mM Tris, pH 8.0, 200 mM Li2SO4, 1.1 M AmSO4
Resolution 2.70 Å R-free 0.276
8U5Y human RADX trimer bound to ssDNA Deposited 2023-09-13 Different construct Different mutation/modification Different oligomeric state Different experimental method Different experimental conditions Different structure-quality metrics Assembly 1 Protein–DNA Homooligomer；Protein × 3 PDB declaration: tetrameric
Chain A 1–855（855 aa）
Chain B 1–855（855 aa）
Chain C 1–855（855 aa）
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 7.5
cryo-EM vitrification conditions Cryogen HELIUM
Resolution 3.01 Å
8U61 Human RADX tetramer bound to ssDNA Deposited 2023-09-13 Different construct Different mutation/modification Different oligomeric state Different experimental method Different experimental conditions Different structure-quality metrics Assembly 1 Protein–DNA Homooligomer；Protein × 4 PDB declaration: pentameric
Chain A 1–855（855 aa）
Chain B 1–855（855 aa）
Chain C 1–855（855 aa）
Chain D 1–855（855 aa）
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 7.5
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 4.00 Å

3 other PDB entries and 18 assemblies. Open the comparison page and filter oligomeric states

View Construct and Data Evidence
UniProt name RADX_HUMAN
Isoform —
PDB entities 1
Chains and sequence ranges Author chain A； PDBConstruct 1–8； UniProt 509–516 Author chain C； PDBConstruct 1–8； UniProt 509–516

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

SAXS scattering curve SAXS Profile

SAXS profile for 7srk

P(r) Distance Distribution P(r) Distribution

P(r) distribution for 7srk
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2. Structure Basics 2. Structure Basics

Entry ID entry_id7srk
Deposition date deposition_date2021-11-08
Structure title titleSingle chain trimer HLA-A*24:02 (Y108C, A163C) with 8mer peptide YPPVPETF
Keywords keywordsHLA, VHH, HPV, SCT, IMMUNE SYSTEM; IMMUNE SYSTEM
Experimental Method methodX-RAY DIFFRACTION
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3. SAXS Parameters (CRYSOL theoretical calculation) 3. SAXS Parameters (CRYSOL)

Radius of gyration Rg (Guinier) rg_guinier32.17 Å
Radius of gyration Rg (electron density) rg_electron31.34 Å
Forward intensity I(0) i0198560000.00
Molecular weight molecular_weight107720.0 kDa
Excluded volume excluded_volume132540 ų
Envelope volume envelope_volume174560 ų
Hydration-shell volume shell_volume45808 ų
Envelope diameter envelope_diameter108.6 Å
Shell Rg shell_rg38.82 Å
Envelope Rg envelope_rg31.13 Å
Shape Rg shape_rg31.33 Å
Total Rg total_rg31.98 Å
Total atoms total_atoms7602
Residues n_residues983
Spherical-harmonic order n_harmonics20
q range q_range— – 0.5000 Å−1
Data points n_points101
Shell type shell_typedirectional
Solvent electron density solvent_density0.3340 e/ų
Shell contrast contrast_shell0.0300 e/ų
CRYSOL version crysol_version4.1.3
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4. P(r) Distance Distribution (GNOM inversion) 4. P(r) Analysis (GNOM)

Maximum dimension Dmax dmax103.8 Å
Rg (real space) rg_real32.02 Å
Rg uncertainty (real space) rg_real_error0.76 Å
I(0) (real space) i0_real1.9860e+08
I(0) uncertainty (real space) i0_real_error2.9630e+06
Rg (reciprocal space) rg_reciprocal32.08 Å
I(0) (reciprocal space) i0_reciprocal198600000.0000
Solution quality estimate total_estimate0.8761
Solution quality rating solution_quality GOOD a GOOD solution
P(r) peaks n_peaks2
Primary peak position r_peak_primary42.4 Å
Skewness Skewness skewness0.241
Kurtosis Kurtosis kurtosis-0.196
Angular range angular_range— – 0.2450 Å−1
Current regularization parameter α current_alpha0.0000
Highest regularization parameter α highest_alpha24460000.0000
Real-space data points n_real_points50
GNOM version gnom_version4.1.3
Quality Criteria quality_criteria AN1: 0.000; Oscil: 0.843; Stabil: 1.000; Sysdev: 1.000; Positv: 1.000; Valcen: 0.990; Smooth: 0.867
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5. Crystallography and Experiment 5. Crystallography & Experiment

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6. Entities and Polymers Entities & Polymers (3)

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7. Fold Classification (SCOP + CATH) 2 domains

CATH v4.4 (2 domains)

Domain ID domain_id7srkB01
Class class2 — Mainly Beta
Architecture architecture60 — Sandwich
Topology topology40 — Immunoglobulin-like
Homologous superfamily homologous superfamily10 — Immunoglobulins
Domain ID domain_id7srkD01
Class class2 — Mainly Beta
Architecture architecture60 — Sandwich
Topology topology40 — Immunoglobulin-like
Homologous superfamily homologous superfamily10 — Immunoglobulins
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8. Citations (1)

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9. Files and Curves (10)