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7z4o

Influenza A/H7N9 polymerase core dimer with Pol II pSer5 CTD peptide mimic bound in site 2A

Method: X-RAY DIFFRACTION
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1. Protein Identity and Related Structures Protein Identity & Related Structures

Polymerase acidic protein

Influenza A virus

UniProt M9TI86

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Heteromer Protein 4 RNA 1 RNA-directed RNA polymerase catalytic subunit × 1 （A0A024E3M6） Polymerase basic protein 2 × 1 （X5F427） SER-TYR-SER-PRO-THR-SEP-PRO-SER-TYR-SER × 1 ;RNA (5'-R(P*AP*GP*UP*AP*GP*UP*AP*AP*CP*AP*AP*G)-3') ; × 1 MAGNESIUM ION × 1 Consistent with all polymers
2 Protein–RNA Heteromer Protein 4 RNA 1 RNA-directed RNA polymerase catalytic subunit × 1 （A0A024E3M6） Polymerase basic protein 2 × 1 （X5F427） SER-TYR-SER-PRO-THR-SEP-PRO-SER-TYR-SER × 1 ;RNA (5'-R(P*AP*GP*UP*AP*GP*UP*AP*AP*CP*AP*AP*G)-3') ; × 1 MAGNESIUM ION × 1 Consistent with all polymers

Other States of the Same Protein in the Database

Monomer

None

Homodimer

None

Homotetramer

None

Other homooligomers

None

Heteromeric or nucleic-acid complex
6tu5 7qtl 7r0e 7z4o 7z4o 7zpl 7zpm 8bek 8pm0 8pnp 8pnq 8poh

23 assemblies; showing the first 12

View Construct and Data Evidence
UniProt name M9TI86_9INFA
Isoform —
PDB entities 1
Chains and sequence ranges Author chain AAA； PDBConstruct 2–517； UniProt 201–716 Author chain DDD； PDBConstruct 2–517； UniProt 201–716

RNA-directed RNA polymerase catalytic subunit

Influenza A virus

UniProt A0A024E3M6

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Heteromer Protein 4 RNA 1 Polymerase acidic protein × 1 （M9TI86） Polymerase basic protein 2 × 1 （X5F427） SER-TYR-SER-PRO-THR-SEP-PRO-SER-TYR-SER × 1 ;RNA (5'-R(P*AP*GP*UP*AP*GP*UP*AP*AP*CP*AP*AP*G)-3') ; × 1 MAGNESIUM ION × 1 Consistent with all polymers
2 Protein–RNA Heteromer Protein 4 RNA 1 Polymerase acidic protein × 1 （M9TI86） Polymerase basic protein 2 × 1 （X5F427） SER-TYR-SER-PRO-THR-SEP-PRO-SER-TYR-SER × 1 ;RNA (5'-R(P*AP*GP*UP*AP*GP*UP*AP*AP*CP*AP*AP*G)-3') ; × 1 MAGNESIUM ION × 1 Consistent with all polymers

Other States of the Same Protein in the Database

Monomer

None

Homodimer

None

Homotetramer

None

Other homooligomers

None

Heteromeric or nucleic-acid complex
7z4o 7z4o

2 assemblies

View Construct and Data Evidence
UniProt name A0A024E3M6_9INFA
Isoform —
PDB entities 2
Chains and sequence ranges Author chain BBB； PDBConstruct 1–757； UniProt 1–757 Author chain EEE； PDBConstruct 1–757； UniProt 1–757

Polymerase basic protein 2

Influenza A virus

UniProt X5F427

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Heteromer Protein 4 RNA 1 Polymerase acidic protein × 1 （M9TI86） RNA-directed RNA polymerase catalytic subunit × 1 （A0A024E3M6） SER-TYR-SER-PRO-THR-SEP-PRO-SER-TYR-SER × 1 ;RNA (5'-R(P*AP*GP*UP*AP*GP*UP*AP*AP*CP*AP*AP*G)-3') ; × 1 MAGNESIUM ION × 1 Consistent with all polymers
2 Protein–RNA Heteromer Protein 4 RNA 1 Polymerase acidic protein × 1 （M9TI86） RNA-directed RNA polymerase catalytic subunit × 1 （A0A024E3M6） SER-TYR-SER-PRO-THR-SEP-PRO-SER-TYR-SER × 1 ;RNA (5'-R(P*AP*GP*UP*AP*GP*UP*AP*AP*CP*AP*AP*G)-3') ; × 1 MAGNESIUM ION × 1 Consistent with all polymers

Other States of the Same Protein in the Database

Monomer

None

Homodimer

None

Homotetramer

None

Other homooligomers

None

Heteromeric or nucleic-acid complex
6tu5 7qtl 7r0e 7z4o 7z4o 7zpl 7zpm 8bek 8pm0 8pnp 8pnq 8poh

21 assemblies; showing the first 12

View Construct and Data Evidence
UniProt name X5F427_9INFA
Isoform —
PDB entities 3
Chains and sequence ranges Author chain CCC； PDBConstruct 1–128； UniProt 1–128 Author chain FFF； PDBConstruct 1–128； UniProt 1–128

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

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2. Structure Basics 2. Structure Basics

Entry ID entry_id7z4o
Deposition date deposition_date2022-03-04
Structure title titleInfluenza A/H7N9 polymerase core dimer with Pol II pSer5 CTD peptide mimic bound in site 2A
Keywords keywordsInfluenza RNA-dependent RNA polymerase, transcription, cap-snatching, Pol II CTD, RNA BINDING PROTEIN; RNA BINDING PROTEIN
Experimental Method methodX-RAY DIFFRACTION
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3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

7z4o__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

7z4o__assembly_1__model_1 | I(q)

10-2 10-1 106 107 108 q (1/Angstrom) I(q)
100 plotted points; both axes use logarithmic scales.

7z4o__assembly_1__model_1 | P(r) · Pending

The new assembly/model P(r) has not been calculated yet This placeholder does not display legacy data r (Angstrom) P(r)
P(r) will be calculated and displayed separately for the same assembly/model.
Rg（Guinier）33.79 Å
Rg (electron density)33.01 Å
Total Rg33.59 Å
Atom count9976
Residues1226
Excluded volume176720 ų
Maximum q0.500 Å⁻¹
Assembly Model Structure unit Oligomeric description Status CRYSOL Actions
1 1 7z4o__assembly_1__model_1 pentameric （5） Success 4.1.3-1-20251215 (887e7ef) View Download
2 1 7z4o__assembly_2__model_1 pentameric （5） Success 4.1.3-1-20251215 (887e7ef) View Download
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4. Crystallography and Experiment 4. Crystallography & Experiment

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5. Entities and Polymers Entities & Polymers (6)

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7. Citations (1)