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8bf1

High-resolution structure of unliganded PPAR gamma in complex with the peptide PGC-1 alpha

Method: X-RAY DIFFRACTION
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1. Protein Identity and Related Structures Protein Identity & Related Structures

Peroxisome proliferator-activated receptor gamma

Homo sapiens

UniProt P37231

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein heterocomplex Heteromer Protein 2 Peroxisome proliferator-activated receptor gamma coactivator 1-alpha × 1 （Q9UBK2） water × 2 Consistent with protein count

Other States of the Same Protein in the Database

Monomer
1i7i 1i7i 2f4b 2f4b 2om9 2om9 2om9 2om9 2prg 2qmv 2vsr 2vsr

158 assemblies; showing the first 12

Homodimer
1knu 1nyx 1prg 1zeo 2ath 2g0g 2i4j 2i4p 2i4z 2p4y 2pob 2q59

201 assemblies; showing the first 12

Homotetramer
2hwq 2hwr 4em9 4prg 9mah

5 assemblies

Other homooligomers

None

Heteromeric or nucleic-acid complex
1fm6 1fm6 1fm9 1k74 1rdt 1zgy 2fvj 2gtk 2prg 3b1m 3cs8 3cwd

137 assemblies; showing the first 12

View Construct and Data Evidence
UniProt name PPARG_HUMAN
Isoform —
PDB entities 1
Chains and sequence ranges Author chain A； PDBConstruct 12–283； UniProt 234–505

Peroxisome proliferator-activated receptor gamma coactivator 1-alpha

Homo sapiens

UniProt Q9UBK2

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein heterocomplex Heteromer Protein 2 Peroxisome proliferator-activated receptor gamma × 1 （P37231） water × 2 Consistent with protein count

Other States of the Same Protein in the Database

Monomer

None

Homodimer

None

Homotetramer

None

Other homooligomers

None

Heteromeric or nucleic-acid complex
1xb7 3b1m 3cs8 3d24 3d24 3d24 3u9q 3v9t 3v9v 4qjr 4qk4 5z5s

45 assemblies; showing the first 12

View Construct and Data Evidence
UniProt name PRGC1_HUMAN
Isoform —
PDB entities 2
Chains and sequence ranges Author chain B； PDBConstruct 1–19； UniProt 136–154

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

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2. Structure Basics 2. Structure Basics

Entry ID entry_id8bf1
Deposition date deposition_date2022-10-23
Structure title titleHigh-resolution structure of unliganded PPAR gamma in complex with the peptide PGC-1 alpha
Keywords keywordsPPAR gamma activation, co-activator peptide, ligand binding domain, nuclear receptor, NUCLEAR PROTEIN; NUCLEAR PROTEIN
Experimental Method methodX-RAY DIFFRACTION
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3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

8bf1__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

8bf1__assembly_1__model_1 | I(q)

10-2 10-1 105 106 107 q (1/Angstrom) I(q)
100 plotted points; both axes use logarithmic scales.

8bf1__assembly_1__model_1 | P(r) · Pending

The new assembly/model P(r) has not been calculated yet This placeholder does not display legacy data r (Angstrom) P(r)
P(r) will be calculated and displayed separately for the same assembly/model.
Rg（Guinier）20.27 Å
Rg (electron density)19.04 Å
Total Rg20.11 Å
Atom count4438
Residues273
Excluded volume39599 ų
Maximum q0.500 Å⁻¹
Assembly Model Structure unit Oligomeric description Status CRYSOL Actions
1 1 8bf1__assembly_1__model_1 dimeric （2） Success 4.1.3-1-20251215 (887e7ef) View Download
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4. Crystallography and Experiment 4. Crystallography & Experiment

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5. Entities and Polymers Entities & Polymers (3)

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7. Citations (1)