← Back to search
8cua

Human excitatory amino acid transporter 3 (EAAT3) with bound potassium in an intermediate outward facing state

Method: ELECTRON MICROSCOPY
▼

1. Protein Identity and Related Structures Protein Identity & Related Structures

Excitatory amino acid transporter 3

Homo sapiens

UniProt P43005

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein homooligomer Homooligomer Protein 3 POTASSIUM ION × 3 MERCURY (II) ION × 3 water × 3 Consistent with protein count

Other States of the Same Protein in the Database

Monomer
6x2z 8ctd 8cud 8cuj 8cv3 9d68 9d69 9d6a 9p4x 9p4y 9p4z

11 assemblies

Homodimer

None

Homotetramer

None

Other homooligomers
6s3q 6x2l 6x3e 6x3f 7nsg 8ctc 8cua 8cui 8cv2 9d66 9d67

11 assemblies

Heteromeric or nucleic-acid complex

None

View Construct and Data Evidence
UniProt name EAA3_HUMAN
Isoform —
PDB entities 1
Chains and sequence ranges Author chain A； PDBConstruct 3–526； UniProt 1–524 Author chain B； PDBConstruct 3–526； UniProt 1–524 Author chain C； PDBConstruct 3–526； UniProt 1–524

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

▼

2. Structure Basics 2. Structure Basics

Entry ID entry_id8cua
Deposition date deposition_date2022-05-17
Structure title titleHuman excitatory amino acid transporter 3 (EAAT3) with bound potassium in an intermediate outward facing state
Keywords keywordsTRANSPORT PROTEIN; TRANSPORT PROTEIN
Experimental Method methodELECTRON MICROSCOPY
▼

3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

8cua__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

8cua__assembly_1__model_1 | I(q)

10-2 10-1 106 107 108 q (1/Angstrom) I(q)
100 plotted points; both axes use logarithmic scales.

8cua__assembly_1__model_1 | P(r) · Pending

The new assembly/model P(r) has not been calculated yet This placeholder does not display legacy data r (Angstrom) P(r)
P(r) will be calculated and displayed separately for the same assembly/model.
Rg（Guinier）34.03 Å
Rg (electron density)33.26 Å
Total Rg33.95 Å
Atom count9504
Residues1248
Excluded volume175450 ų
Maximum q0.500 Å⁻¹
Assembly Model Structure unit Oligomeric description Status CRYSOL Actions
1 1 8cua__assembly_1__model_1 trimeric （3） Success 4.1.3-1-20251215 (887e7ef) View Download
▶

4. Crystallography and Experiment 4. Crystallography & Experiment

▶

5. Entities and Polymers Entities & Polymers (4)

▼

6. Fold Classification (SCOP + CATH) 3 domains

CATH v4.4 (3 domains)

Domain ID domain_id8cuaA01
Class class1 — Mainly Alpha
Architecture architecture10 — Orthogonal Bundle
Topology topology3860 — Proton glutamate symport protein
Homologous superfamily homologous superfamily10 — Sodium:dicarboxylate symporter
Domain ID domain_id8cuaB01
Class class1 — Mainly Alpha
Architecture architecture10 — Orthogonal Bundle
Topology topology3860 — Proton glutamate symport protein
Homologous superfamily homologous superfamily10 — Sodium:dicarboxylate symporter
Domain ID domain_id8cuaC01
Class class1 — Mainly Alpha
Architecture architecture10 — Orthogonal Bundle
Topology topology3860 — Proton glutamate symport protein
Homologous superfamily homologous superfamily10 — Sodium:dicarboxylate symporter
▶

7. Citations (1)