8eas

Yeast VO in complex with Vma12-22p

Method: ELECTRON MICROSCOPY
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1. Protein Identity and Related Structures Protein Identity & Related Structures

Vacuolar ATPase assembly protein VMA22

OrganismNot specified

UniProt P38784

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein heterocomplex Heteromer Protein 18 V-type proton ATPase assembly factor Vma12p × 1 V-type proton ATPase subunit F × 1 (A0A6A5PYF6) V-type proton ATPase subunit a, vacuolar isoform × 1 (P32563) V0 assembly protein 1 × 1 (P53262) ;V-type proton ATPase subunit c'' ; × 1 (P23968) V-type proton ATPase subunit d × 1 (P32366) V-type proton ATPase subunit e × 1 (Q3E7B6) Yeast V-ATPase subunit f × 1 (P0C5R9) V-type proton ATPase subunit c × 8 (P25515) ;V-type proton ATPase subunit c' ; × 1 (P32842) Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name VMA22_YEAST
Isoform —
PDB entities 1
Chains and sequence ranges Author chain A; PDBConstruct 1–181; UniProt 1–181

V-type proton ATPase subunit F

OrganismNot specified

UniProt A0A6A5PYF6

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein heterocomplex Heteromer Protein 18 Vacuolar ATPase assembly protein VMA22 × 1 (P38784) V-type proton ATPase assembly factor Vma12p × 1 V-type proton ATPase subunit a, vacuolar isoform × 1 (P32563) V0 assembly protein 1 × 1 (P53262) ;V-type proton ATPase subunit c'' ; × 1 (P23968) V-type proton ATPase subunit d × 1 (P32366) V-type proton ATPase subunit e × 1 (Q3E7B6) Yeast V-ATPase subunit f × 1 (P0C5R9) V-type proton ATPase subunit c × 8 (P25515) ;V-type proton ATPase subunit c' ; × 1 (P32842) Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name A0A6A5PYF6_YEASX
Isoform —
PDB entities 3
Chains and sequence ranges Author chain F; PDBConstruct 1–118; UniProt 1–118

V-type proton ATPase subunit a, vacuolar isoform

OrganismNot specified

UniProt P32563

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein heterocomplex Heteromer Protein 18 Vacuolar ATPase assembly protein VMA22 × 1 (P38784) V-type proton ATPase assembly factor Vma12p × 1 V-type proton ATPase subunit F × 1 (A0A6A5PYF6) V0 assembly protein 1 × 1 (P53262) ;V-type proton ATPase subunit c'' ; × 1 (P23968) V-type proton ATPase subunit d × 1 (P32366) V-type proton ATPase subunit e × 1 (Q3E7B6) Yeast V-ATPase subunit f × 1 (P0C5R9) V-type proton ATPase subunit c × 8 (P25515) ;V-type proton ATPase subunit c' ; × 1 (P32842) Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name VPH1_YEAST
Isoform —
PDB entities 4
Chains and sequence ranges Author chain a; PDBConstruct 1–840; UniProt 1–840

V0 assembly protein 1

OrganismNot specified

UniProt P53262

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein heterocomplex Heteromer Protein 18 Vacuolar ATPase assembly protein VMA22 × 1 (P38784) V-type proton ATPase assembly factor Vma12p × 1 V-type proton ATPase subunit F × 1 (A0A6A5PYF6) V-type proton ATPase subunit a, vacuolar isoform × 1 (P32563) ;V-type proton ATPase subunit c'' ; × 1 (P23968) V-type proton ATPase subunit d × 1 (P32366) V-type proton ATPase subunit e × 1 (Q3E7B6) Yeast V-ATPase subunit f × 1 (P0C5R9) V-type proton ATPase subunit c × 8 (P25515) ;V-type proton ATPase subunit c' ; × 1 (P32842) Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name VOA1_YEAST
Isoform —
PDB entities 5
Chains and sequence ranges Author chain b; PDBConstruct 1–265; UniProt 1–265

;V-type proton ATPase subunit c'' ;

OrganismNot specified

UniProt P23968

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein heterocomplex Heteromer Protein 18 Vacuolar ATPase assembly protein VMA22 × 1 (P38784) V-type proton ATPase assembly factor Vma12p × 1 V-type proton ATPase subunit F × 1 (A0A6A5PYF6) V-type proton ATPase subunit a, vacuolar isoform × 1 (P32563) V0 assembly protein 1 × 1 (P53262) V-type proton ATPase subunit d × 1 (P32366) V-type proton ATPase subunit e × 1 (Q3E7B6) Yeast V-ATPase subunit f × 1 (P0C5R9) V-type proton ATPase subunit c × 8 (P25515) ;V-type proton ATPase subunit c' ; × 1 (P32842) Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name VATO_YEAST
Isoform —
PDB entities 6
Chains and sequence ranges Author chain c; PDBConstruct 1–213; UniProt 1–213

V-type proton ATPase subunit d

OrganismNot specified

UniProt P32366

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein heterocomplex Heteromer Protein 18 Vacuolar ATPase assembly protein VMA22 × 1 (P38784) V-type proton ATPase assembly factor Vma12p × 1 V-type proton ATPase subunit F × 1 (A0A6A5PYF6) V-type proton ATPase subunit a, vacuolar isoform × 1 (P32563) V0 assembly protein 1 × 1 (P53262) ;V-type proton ATPase subunit c'' ; × 1 (P23968) V-type proton ATPase subunit e × 1 (Q3E7B6) Yeast V-ATPase subunit f × 1 (P0C5R9) V-type proton ATPase subunit c × 8 (P25515) ;V-type proton ATPase subunit c' ; × 1 (P32842) Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name VA0D_YEAST
Isoform —
PDB entities 7
Chains and sequence ranges Author chain d; PDBConstruct 1–345; UniProt 1–345

V-type proton ATPase subunit e

OrganismNot specified

UniProt Q3E7B6

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein heterocomplex Heteromer Protein 18 Vacuolar ATPase assembly protein VMA22 × 1 (P38784) V-type proton ATPase assembly factor Vma12p × 1 V-type proton ATPase subunit F × 1 (A0A6A5PYF6) V-type proton ATPase subunit a, vacuolar isoform × 1 (P32563) V0 assembly protein 1 × 1 (P53262) ;V-type proton ATPase subunit c'' ; × 1 (P23968) V-type proton ATPase subunit d × 1 (P32366) Yeast V-ATPase subunit f × 1 (P0C5R9) V-type proton ATPase subunit c × 8 (P25515) ;V-type proton ATPase subunit c' ; × 1 (P32842) Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name VA0E_YEAST
Isoform —
PDB entities 8
Chains and sequence ranges Author chain e; PDBConstruct 1–73; UniProt 1–73

Yeast V-ATPase subunit f

OrganismNot specified

UniProt P0C5R9

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein heterocomplex Heteromer Protein 18 Vacuolar ATPase assembly protein VMA22 × 1 (P38784) V-type proton ATPase assembly factor Vma12p × 1 V-type proton ATPase subunit F × 1 (A0A6A5PYF6) V-type proton ATPase subunit a, vacuolar isoform × 1 (P32563) V0 assembly protein 1 × 1 (P53262) ;V-type proton ATPase subunit c'' ; × 1 (P23968) V-type proton ATPase subunit d × 1 (P32366) V-type proton ATPase subunit e × 1 (Q3E7B6) V-type proton ATPase subunit c × 8 (P25515) ;V-type proton ATPase subunit c' ; × 1 (P32842) Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name YP17B_YEAST
Isoform —
PDB entities 9
Chains and sequence ranges Author chain f; PDBConstruct 1–85; UniProt 1–85

V-type proton ATPase subunit c

OrganismNot specified

UniProt P25515

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein heterocomplex Heteromer Protein 18 Vacuolar ATPase assembly protein VMA22 × 1 (P38784) V-type proton ATPase assembly factor Vma12p × 1 V-type proton ATPase subunit F × 1 (A0A6A5PYF6) V-type proton ATPase subunit a, vacuolar isoform × 1 (P32563) V0 assembly protein 1 × 1 (P53262) ;V-type proton ATPase subunit c'' ; × 1 (P23968) V-type proton ATPase subunit d × 1 (P32366) V-type proton ATPase subunit e × 1 (Q3E7B6) Yeast V-ATPase subunit f × 1 (P0C5R9) ;V-type proton ATPase subunit c' ; × 1 (P32842) Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name VATL1_YEAST
Isoform —
PDB entities 10
Chains and sequence ranges Author chain g; PDBConstruct 1–160; UniProt 1–160 Author chain h; PDBConstruct 1–160; UniProt 1–160 Author chain i; PDBConstruct 1–160; UniProt 1–160 Author chain j; PDBConstruct 1–160; UniProt 1–160 Author chain k; PDBConstruct 1–160; UniProt 1–160 Author chain l; PDBConstruct 1–160; UniProt 1–160 Author chain m; PDBConstruct 1–160; UniProt 1–160 Author chain n; PDBConstruct 1–160; UniProt 1–160

;V-type proton ATPase subunit c' ;

OrganismNot specified

UniProt P32842

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein heterocomplex Heteromer Protein 18 Vacuolar ATPase assembly protein VMA22 × 1 (P38784) V-type proton ATPase assembly factor Vma12p × 1 V-type proton ATPase subunit F × 1 (A0A6A5PYF6) V-type proton ATPase subunit a, vacuolar isoform × 1 (P32563) V0 assembly protein 1 × 1 (P53262) ;V-type proton ATPase subunit c'' ; × 1 (P23968) V-type proton ATPase subunit d × 1 (P32366) V-type proton ATPase subunit e × 1 (Q3E7B6) Yeast V-ATPase subunit f × 1 (P0C5R9) V-type proton ATPase subunit c × 8 (P25515) Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name VATL2_YEAST
Isoform —
PDB entities 11
Chains and sequence ranges Author chain o; PDBConstruct 1–164; UniProt 1–164

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

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2. Structure Basics 2. Structure Basics

Entry ID entry_id8eas
Deposition date deposition_date2022-08-29
Structure title titleYeast VO in complex with Vma12-22p
Keywords keywordsV-type, ATPase, assembly, proton, MEMBRANE PROTEIN; MEMBRANE PROTEIN
Experimental Method methodELECTRON MICROSCOPY
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3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

8eas__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

8eas__assembly_1__model_1 | I(q)

10-2 10-1 106 107 108 109 q (1/Angstrom) I(q)
100 plotted points; both axes use logarithmic scales.

8eas__assembly_1__model_1 | P(r) · Pending

The new assembly/model P(r) has not been calculated yet This placeholder does not display legacy data r (Angstrom) P(r)
P(r) will be calculated and displayed separately for the same assembly/model.
Rg(Guinier)46.58 Å
Rg (electron density)45.97 Å
Total Rg46.23 Å
Atom count24802
Residues3280
Excluded volume450710 ų
Maximum q0.500 Å⁻¹
Assembly Model Structure unit Oligomeric description Status CRYSOL Actions
1 1 8eas__assembly_1__model_1 octadecameric (18) Success 4.1.3-1-20251215 (887e7ef) View Download
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4. Crystallography and Experiment 4. Crystallography & Experiment

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5. Entities and Polymers Entities & Polymers (11)

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6. Fold Classification (SCOP + CATH) 1 domains

CATH v4.4 (1 domains)

Domain ID domain_id8easo01
Class class1 — Mainly Alpha
Architecture architecture20 — Up-down Bundle
Topology topology120 — Four Helix Bundle (Hemerythrin (Met), subunit A)
Homologous superfamily homologous superfamily610 — lithium bound rotor ring of v- atpase
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7. Citations (2)