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8h7a

Crystal structure of the dimer form KAT6A WH domain with its bound double stranded DNA

Method: X-RAY DIFFRACTION
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1. Protein Identity and Related Structures Protein Identity & Related Structures

Histone acetyltransferase KAT6A

Homo sapiens

UniProt Q92794

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–DNA Homooligomer Protein 2 DNA 2 ;DNA (5'-D(*GP*GP*TP*CP*CP*GP*AP*CP*GP*GP*AP*CP*C)-3') ; × 1 ;DNA (5'-D(*GP*GP*TP*CP*CP*GP*TP*CP*GP*GP*AP*CP*C)-3') ; × 1 MAGNESIUM ION × 2 water × 4 Consistent with all polymers
2 Protein–DNA Homooligomer Protein 2 DNA 2 ;DNA (5'-D(*GP*GP*TP*CP*CP*GP*AP*CP*GP*GP*AP*CP*C)-3') ; × 1 ;DNA (5'-D(*GP*GP*TP*CP*CP*GP*TP*CP*GP*GP*AP*CP*C)-3') ; × 1 MAGNESIUM ION × 2 water × 4 Consistent with all polymers

Other States of the Same Protein in the Database

Monomer
1m36 2ln0 2ozu 2rc4 4ljn 8dd5

6 assemblies

Homodimer
9fkr

1 assemblies

Homotetramer

None

Other homooligomers

None

Heteromeric or nucleic-acid complex
3v43 4lk9 4lka 4llb 4llb 5b75 5b76 5b77 5b78 6lsb 7y43 8h7a

17 assemblies; showing the first 12

View Construct and Data Evidence
UniProt name KAT6A_HUMAN
Isoform —
PDB entities 1
Chains and sequence ranges Author chain A； PDBConstruct 2–86； UniProt 1–85 Author chain B； PDBConstruct 2–86； UniProt 1–85 Author chain E； PDBConstruct 2–86； UniProt 1–85 Author chain F； PDBConstruct 2–86； UniProt 1–85

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

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2. Structure Basics 2. Structure Basics

Entry ID entry_id8h7a
Deposition date deposition_date2022-10-19
Structure title titleCrystal structure of the dimer form KAT6A WH domain with its bound double stranded DNA
Keywords keywordsCpG islands, Winged-helix domain, acetyltransferase, DNA BINDING PROTEIN-DNA COMPLEX; DNA BINDING PROTEIN/DNA
Experimental Method methodX-RAY DIFFRACTION
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3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

8h7a__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

8h7a__assembly_1__model_1 | I(q)

10-2 10-1 105 106 107 q (1/Angstrom) I(q)
100 plotted points; both axes use logarithmic scales.

8h7a__assembly_1__model_1 | P(r) · Pending

The new assembly/model P(r) has not been calculated yet This placeholder does not display legacy data r (Angstrom) P(r)
P(r) will be calculated and displayed separately for the same assembly/model.
Rg（Guinier）18.34 Å
Rg (electron density)17.79 Å
Total Rg18.63 Å
Atom count1743
Residues180
Excluded volume29485 ų
Maximum q0.500 Å⁻¹
Assembly Model Structure unit Oligomeric description Status CRYSOL Actions
1 1 8h7a__assembly_1__model_1 tetrameric （4） Success 4.1.3-1-20251215 (887e7ef) View Download
2 1 8h7a__assembly_2__model_1 tetrameric （4） Success 4.1.3-1-20251215 (887e7ef) View Download
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4. Crystallography and Experiment 4. Crystallography & Experiment

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5. Entities and Polymers Entities & Polymers (5)

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7. Citations (1)