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8ifo

Crystal structure of estrogen related receptor-gamma DNA binding domain complexed with Pla2g12b promoter

Method: X-RAY DIFFRACTION
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1. Protein Identity and Related Structures Protein Identity & Related Structures

Estrogen-related receptor gamma

Homo sapiens

UniProt P62508

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–DNA Homooligomer Protein 2 DNA 2 ;DNA (5'-D(*GP*AP*GP*GP*AP*CP*AP*AP*AP*GP*GP*TP*GP*AP*AP*AP*C)-3') ; × 1 ;DNA (5'-D(*GP*TP*TP*TP*CP*AP*CP*CP*TP*TP*TP*GP*TP*CP*CP*TP*C)-3') ; × 1 ZINC ION × 5 MALONATE ION × 2 water × 4 Consistent with all polymers
2 Protein–DNA Monomer Protein 1 DNA 2 ;DNA (5'-D(*GP*AP*GP*GP*AP*CP*AP*AP*AP*GP*GP*TP*GP*AP*AP*AP*C)-3') ; × 1 ;DNA (5'-D(*GP*TP*TP*TP*CP*AP*CP*CP*TP*TP*TP*GP*TP*CP*CP*TP*C)-3') ; × 1 ZINC ION × 2 MALONATE ION × 1 water × 3 Consistent with all polymers

Other States of the Same Protein in the Database

Monomer
2p7a 2p7g 2p7z 5yso 5yso 5yso 6a6k 6a6k 6a6k 6knr 6knr

11 assemblies

Homodimer
2e2r 2ewp 2ewp 2ewp 2gp7 2gp7 2gpu 2zas 2zbs 2zkc 6i61 6i62

18 assemblies; showing the first 12

Homotetramer

None

Other homooligomers

None

Heteromeric or nucleic-acid complex
1kv6 1tfc 2gpo 2gpp 2gpv 2gpv 8b4q 8bjg 8bjn 8bm5 8ifo 8ifo

17 assemblies; showing the first 12

View Construct and Data Evidence
UniProt name ERR3_HUMAN
Isoform —
PDB entities 1
Chains and sequence ranges Author chain A； PDBConstruct 1–97； UniProt 123–219 Author chain B； PDBConstruct 1–97； UniProt 123–219 Author chain F； PDBConstruct 1–97； UniProt 123–219

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

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2. Structure Basics 2. Structure Basics

Entry ID entry_id8ifo
Deposition date deposition_date2023-02-19
Structure title titleCrystal structure of estrogen related receptor-gamma DNA binding domain complexed with Pla2g12b promoter
Keywords keywordsnuclear receptor, ERR3, PLA2G12B, DR1, TRANSCRIPTION; TRANSCRIPTION
Experimental Method methodX-RAY DIFFRACTION
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3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

8ifo__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

8ifo__assembly_1__model_1 | I(q)

10-2 10-1 105 106 107 q (1/Angstrom) I(q)
100 plotted points; both axes use logarithmic scales.

8ifo__assembly_1__model_1 | P(r) · Pending

The new assembly/model P(r) has not been calculated yet This placeholder does not display legacy data r (Angstrom) P(r)
P(r) will be calculated and displayed separately for the same assembly/model.
Rg（Guinier）20.27 Å
Rg (electron density)20.04 Å
Total Rg20.80 Å
Atom count1925
Residues190
Excluded volume32271 ų
Maximum q0.500 Å⁻¹
Assembly Model Structure unit Oligomeric description Status CRYSOL Actions
1 1 8ifo__assembly_1__model_1 tetrameric （4） Success 4.1.3-1-20251215 (887e7ef) View Download
2 1 8ifo__assembly_2__model_1 trimeric （3） Success 4.1.3-1-20251215 (887e7ef) View Download
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4. Crystallography and Experiment 4. Crystallography & Experiment

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5. Entities and Polymers Entities & Polymers (6)

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7. Citations (1)