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8jce

Cryo-EM Structure of Chikungunya Virus Nonstructural Protein 1 with m7GpppAmU

Method: ELECTRON MICROSCOPY
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1. Protein Identity and Related Structures Protein Identity & Related Structures

mRNA-capping enzyme nsP1

Chikungunya virus strain S27-African prototype

UniProt Q8JUX6

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein homooligomer Homooligomer Protein 12 ZINC ION × 12 S-ADENOSYL-L-HOMOCYSTEINE × 12 ;[(2~{R},3~{R},4~{R},5~{R})-5-(6-azanyl-7,8-dihydropurin-9-yl)-2-[[[[[(2~{R},3~{S},4~{R},5~{R})-5-(2-azanyl-7-methyl-6-oxidanylidene-1,8-dihydropurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl]oxy-oxidanyl-phosphoryl]oxy-oxidanyl-phosphoryl]oxymethyl]-4-methoxy-oxolan-3-yl] [(2~{R},3~{S},4~{R},5~{S})-5-[2,4-bis(oxidanylidene)pyrimidin-1-yl]-3,4-bis(oxidanyl)oxolan-2-yl]methyl hydrogen phosphate ; × 12 MAGNESIUM ION × 12 water × 12 Consistent with protein count

Other States of the Same Protein in the Database

Monomer
3gpg 3gpg 3gpg 3gpg 3gpo 3gpo 3gpo 3gpo 3gpq 3gpq 4tu0 4tu0

585 assemblies; showing the first 12

Homodimer

None

Homotetramer

None

Other homooligomers
6z0u 6z0v 7dop 7fgg 7fgh 7x01 8aov 8aow 8aox 8apx 8axv 8jce

14 assemblies; showing the first 12

Heteromeric or nucleic-acid complex
3gpq 3gpq 4tu0 4tu0 7fgi 7y38

6 assemblies

View Construct and Data Evidence
UniProt name POLN_CHIKS
Isoform —
PDB entities 1
Chains and sequence ranges Author chain A； PDBConstruct 1–516； UniProt 1–516 Author chain B； PDBConstruct 1–516； UniProt 1–516 Author chain C； PDBConstruct 1–516； UniProt 1–516 Author chain D； PDBConstruct 1–516； UniProt 1–516 Author chain E； PDBConstruct 1–516； UniProt 1–516 Author chain F； PDBConstruct 1–516； UniProt 1–516 Author chain G； PDBConstruct 1–516； UniProt 1–516 Author chain H； PDBConstruct 1–516； UniProt 1–516 Author chain I； PDBConstruct 1–516； UniProt 1–516 Author chain J； PDBConstruct 1–516； UniProt 1–516 Author chain K； PDBConstruct 1–516； UniProt 1–516 Author chain L； PDBConstruct 1–516； UniProt 1–516

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

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2. Structure Basics 2. Structure Basics

Entry ID entry_id8jce
Deposition date deposition_date2023-05-11
Structure title titleCryo-EM Structure of Chikungunya Virus Nonstructural Protein 1 with m7GpppAmU
Keywords keywordsnonstructural protein, Chikungunya virus, RNA cap, replication, VIRAL PROTEIN; VIRAL PROTEIN
Experimental Method methodELECTRON MICROSCOPY
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3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

8jce__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

8jce__assembly_1__model_1 | I(q)

10-2 10-1 106 107 108 109 q (1/Angstrom) I(q)
100 plotted points; both axes use logarithmic scales.

8jce__assembly_1__model_1 | P(r) · Pending

The new assembly/model P(r) has not been calculated yet This placeholder does not display legacy data r (Angstrom) P(r)
P(r) will be calculated and displayed separately for the same assembly/model.
Rg（Guinier）72.31 Å
Rg (electron density)72.05 Å
Total Rg72.23 Å
Atom count43644
Residues5436
Excluded volume774710 ų
Maximum q0.500 Å⁻¹
Assembly Model Structure unit Oligomeric description Status CRYSOL Actions
1 1 8jce__assembly_1__model_1 dodecameric （12） Success 4.1.3-1-20251215 (887e7ef) View Download
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4. Crystallography and Experiment 4. Crystallography & Experiment

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5. Entities and Polymers Entities & Polymers (6)

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7. Citations (1)