SAXSdb — 8piu

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1. Protein Identity and Related Structures Protein Identity & Related Structures

Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial

Homo sapiens

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein homooligomer	Homooligomer	Protein 60	No other associated polymer	Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	ODP2_HUMAN
Isoform	—
PDB entities	1
Chains and sequence ranges	Author chain A； PDBConstruct 2–562； UniProt 87–647 Author chain AA； PDBConstruct 2–562； UniProt 87–647 Author chain AB； PDBConstruct 2–562； UniProt 87–647 Author chain B； PDBConstruct 2–562； UniProt 87–647 Author chain BA； PDBConstruct 2–562； UniProt 87–647 Author chain BB； PDBConstruct 2–562； UniProt 87–647 Author chain C； PDBConstruct 2–562； UniProt 87–647 Author chain CA； PDBConstruct 2–562； UniProt 87–647 Author chain CB； PDBConstruct 2–562； UniProt 87–647 Author chain D； PDBConstruct 2–562； UniProt 87–647 Author chain DA； PDBConstruct 2–562； UniProt 87–647 Author chain DB； PDBConstruct 2–562； UniProt 87–647 Author chain E； PDBConstruct 2–562； UniProt 87–647 Author chain EA； PDBConstruct 2–562； UniProt 87–647 Author chain EB； PDBConstruct 2–562； UniProt 87–647 Author chain F； PDBConstruct 2–562； UniProt 87–647 Author chain FA； PDBConstruct 2–562； UniProt 87–647 Author chain FB； PDBConstruct 2–562； UniProt 87–647 Author chain G； PDBConstruct 2–562； UniProt 87–647 Author chain GA； PDBConstruct 2–562； UniProt 87–647 Author chain GB； PDBConstruct 2–562； UniProt 87–647 Author chain H； PDBConstruct 2–562； UniProt 87–647 Author chain HA； PDBConstruct 2–562； UniProt 87–647 Author chain HB； PDBConstruct 2–562； UniProt 87–647 Author chain I； PDBConstruct 2–562； UniProt 87–647 Author chain IA； PDBConstruct 2–562； UniProt 87–647 Author chain IB； PDBConstruct 2–562； UniProt 87–647 Author chain J； PDBConstruct 2–562； UniProt 87–647 Author chain JA； PDBConstruct 2–562； UniProt 87–647 Author chain K； PDBConstruct 2–562； UniProt 87–647 Author chain KA； PDBConstruct 2–562； UniProt 87–647 Author chain L； PDBConstruct 2–562； UniProt 87–647 Author chain LA； PDBConstruct 2–562； UniProt 87–647 Author chain M； PDBConstruct 2–562； UniProt 87–647 Author chain MA； PDBConstruct 2–562； UniProt 87–647 Author chain N； PDBConstruct 2–562； UniProt 87–647 Author chain NA； PDBConstruct 2–562； UniProt 87–647 Author chain O； PDBConstruct 2–562； UniProt 87–647 Author chain OA； PDBConstruct 2–562； UniProt 87–647 Author chain P； PDBConstruct 2–562； UniProt 87–647 Author chain PA； PDBConstruct 2–562； UniProt 87–647 Author chain Q； PDBConstruct 2–562； UniProt 87–647 Author chain QA； PDBConstruct 2–562； UniProt 87–647 Author chain R； PDBConstruct 2–562； UniProt 87–647 Author chain RA； PDBConstruct 2–562； UniProt 87–647 Author chain S； PDBConstruct 2–562； UniProt 87–647 Author chain SA； PDBConstruct 2–562； UniProt 87–647 Author chain T； PDBConstruct 2–562； UniProt 87–647 Author chain TA； PDBConstruct 2–562； UniProt 87–647 Author chain UA； PDBConstruct 2–562； UniProt 87–647 Author chain V； PDBConstruct 2–562； UniProt 87–647 Author chain VA； PDBConstruct 2–562； UniProt 87–647 Author chain W； PDBConstruct 2–562； UniProt 87–647 Author chain WA； PDBConstruct 2–562； UniProt 87–647 Author chain X； PDBConstruct 2–562； UniProt 87–647 Author chain XA； PDBConstruct 2–562； UniProt 87–647 Author chain Y； PDBConstruct 2–562； UniProt 87–647 Author chain YA； PDBConstruct 2–562； UniProt 87–647 Author chain Z； PDBConstruct 2–562； UniProt 87–647 Author chain ZA； PDBConstruct 2–562； UniProt 87–647

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

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2. Structure Basics 2. Structure Basics

Entry ID entry_id	8piu
Deposition date deposition_date	2023-06-22
Structure title title	60-meric complex of dihydrolipoamide acetyltransferase (E2) of the human pyruvate dehydrogenase complex
Keywords keywords	pyruvate dehydrogenase complex, PDHc, E2, cryo-EM, TRANSFERASE; TRANSFERASE
Experimental Method method	ELECTRON MICROSCOPY

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3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

8piu__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

8piu__assembly_1__model_1 | I(q)

100 plotted points; both axes use logarithmic scales.

8piu__assembly_1__model_1 | P(r) · Pending

P(r) will be calculated and displayed separately for the same assembly/model.

Rg（Guinier）	99.46 Å
Rg (electron density)	97.60 Å
Total Rg	97.58 Å
Atom count	106140
Residues	13860
Excluded volume	1914900 Å³
Maximum q	0.500 Å⁻¹

Assembly	Model	Structure unit	Oligomeric description	Status	CRYSOL	Actions
1	1	`8piu__assembly_1__model_1`	60-meric （60）	Success	4.1.3-1-20251215 (887e7ef)	View Download

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4. Crystallography and Experiment 4. Crystallography & Experiment

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5. Entities and Polymers Entities & Polymers (1)

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Unit-cell length a length_a	1.000 Å
Unit-cell length b length_b	1.000 Å
Unit-cell length c length_c	1.000 Å
Unit-cell angle α angle_alpha	90.00 °
Unit-cell angle β angle_beta	90.00 °
Unit-cell angle γ angle_gamma	90.00 °
Molecules per unit cell Z z_pdb	—

Space group space_group	P 1
Space-group number int_tables_number	1
Crystal system crystal_system	—

Resolution resolution	2.90 Å
Resolution测定Method resolution_method	—
颗粒数 num_particles	83959

Description description	Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial
Molecular weight formula_weight	59811.8 kDa
EC 编号 ec_number	2.3.1.12
Source method src_method	man
Copy count entity_count	60

Polymer type type	polypeptide(L)
Chain IDs strand_id	;B,AB,A,BB,CB,DB,EB,FB,GB,HB,IB,C,D,E,F,G,H,I,J,K,L,M,N,O,P,Q,R,BA,S,T,V,W,X,Y,Z,AA,CA,DA,EA,FA,GA,HA,IA,JA,KA,LA,MA,NA,OA,PA,QA,RA,SA,TA,UA,VA,WA,XA,YA,ZA ;
Atom count atom_count	106140

60-meric complex of dihydrolipoamide acetyltransferase (E2) of the human pyruvate dehydrogenase complex

1. Protein Identity and Related Structures Protein Identity & Related Structures

Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial

State in the Current Structure

Other States of the Same Protein in the Database

2. Structure Basics 2. Structure Basics

3. Official assembly/model SAXS Official SAXS Profiles

8piu__assembly_1__model_1

8piu__assembly_1__model_1 | I(q)

8piu__assembly_1__model_1 | P(r) · Pending

4. Crystallography and Experiment 4. Crystallography & Experiment

Unit cell Unit Cell

Symmetry Symmetry

冷冻电镜 EM 3D

5. Entities and Polymers Entities & Polymers (1)

Entity 1 Entity 1 polymer

Polymer Polymer

Source Source

7. Citations (1)

Source organism organism	Homo sapiens
Common name common_name	human
NCBI taxonomy ID ncbi_taxonomy_id	9606
Host organism host_organism	Escherichia coli BL21(DE3)

60-meric complex of dihydrolipoamide acetyltransferase (E2) of the human pyruvate dehydrogenase complex

1. Protein Identity and Related Structures Protein Identity & Related Structures

Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial

State in the Current Structure

Other States of the Same Protein in the Database

Monomer

Homodimer

Homotetramer

Other homooligomers

Heteromeric or nucleic-acid complex

2. Structure Basics 2. Structure Basics

3. Official assembly/model SAXS Official SAXS Profiles

8piu__assembly_1__model_1

8piu__assembly_1__model_1 | I(q)

8piu__assembly_1__model_1 | P(r) · Pending

4. Crystallography and Experiment 4. Crystallography & Experiment

Unit cell Unit Cell

Symmetry Symmetry

冷冻电镜 EM 3D

5. Entities and Polymers Entities & Polymers (1)

Entity 1 Entity 1 polymer

Polymer Polymer

Source Source

7. Citations (1)