|
22TU
Human 80S ribosome in complex with DHX29
Deposited 2026-01-22
|
Different oligomeric state
Different ligand/ion
Different experimental conditions
Different structure-quality metrics
|
Assembly 1
Protein–RNA
Heteromer；Protein × 77
PDB declaration: 83-meric
|
Chain SN
1–151（151 aa）
|
Not recorded
|
MG MAGNESIUM ION × 191
ZN ZINC ION × 8
|
ELECTRON MICROSCOPY
cryo-EM buffer
pH 7.5
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 3.00 Å
|
|
28LN
XBP1u-stalled RPL4 RNC in complex with NAC
Deposited 2026-02-05
|
Different oligomeric state
Different ligand/ion
Different experimental conditions
Different structure-quality metrics
|
Assembly 1
Protein–RNA
Heteromer；Protein × 80
PDB declaration: 86-meric
|
Chain AN
1–151（151 aa）
|
Not recorded
|
No recorded non-water small molecule
|
ELECTRON MICROSCOPY
mmCIF provides none of the parsed conditions
|
Resolution 2.70 Å
|
|
28ZU
human 48S PIC with Kozak mRNA and eIF1A W70A mutant
Deposited 2026-03-03
|
Different oligomeric state
Different ligand/ion
Different experimental conditions
Different structure-quality metrics
|
Assembly 1
Protein–RNA
Heteromer；Protein × 38
PDB declaration: 41-meric
|
Chain SN
1–151（151 aa）
|
Not recorded
|
No recorded non-water small molecule
|
ELECTRON MICROSCOPY
mmCIF provides none of the parsed conditions
|
Resolution 3.20 Å
|
|
28ZV
human 48S PIC with mRNA (non-Kozak)
Deposited 2026-03-03
|
Different oligomeric state
Different ligand/ion
Different experimental conditions
Different structure-quality metrics
|
Assembly 1
Protein–RNA
Heteromer；Protein × 38
PDB declaration: 41-meric
|
Chain SN
1–151（151 aa）
|
Not recorded
|
No recorded non-water small molecule
|
ELECTRON MICROSCOPY
mmCIF provides none of the parsed conditions
|
Resolution 2.90 Å
|
|
28ZX
human 48S PIC with mRNA (Kozak_1)
Deposited 2026-03-03
|
Different oligomeric state
Different ligand/ion
Different experimental conditions
Different structure-quality metrics
|
Assembly 1
Protein–RNA
Heteromer；Protein × 47
PDB declaration: 50-meric
|
Chain SN
1–151（151 aa）
|
Not recorded
|
No recorded non-water small molecule
|
ELECTRON MICROSCOPY
mmCIF provides none of the parsed conditions
|
Resolution 2.80 Å
|
|
28ZY
human 48S PIC with mRNA (Kozak_2)
Deposited 2026-03-03
|
Different oligomeric state
Different ligand/ion
Different experimental conditions
Different structure-quality metrics
|
Assembly 1
Protein–RNA
Heteromer；Protein × 47
PDB declaration: 50-meric
|
Chain SN
1–151（151 aa）
|
Not recorded
|
No recorded non-water small molecule
|
ELECTRON MICROSCOPY
mmCIF provides none of the parsed conditions
|
Resolution 3.00 Å
|
|
4UG0
STRUCTURE OF THE HUMAN 80S RIBOSOME
Deposited 2015-03-20
|
Different oligomeric state
Different ligand/ion
Different experimental conditions
Different structure-quality metrics
|
Assembly 1
Protein–RNA
Heteromer；Protein × 76
PDB declaration: 89-meric
|
Chain SN
1–151（151 aa）
|
Not recorded
|
MG MAGNESIUM ION × 239
ZN ZINC ION × 6
|
ELECTRON MICROSCOPY
cryo-EM buffer
pH 7.6
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 3.60 Å
|
|
4V6X
Structure of the human 80S ribosome
Deposited 2013-02-27
|
Different oligomeric state
Different ligand/ion
Different experimental conditions
Different structure-quality metrics
|
Assembly 1
Protein–RNA
Heteromer；Protein × 84
PDB declaration: 89-meric
|
Chain AN
1–151（151 aa）
|
Not recorded
|
No recorded non-water small molecule
|
ELECTRON MICROSCOPY
cryo-EM buffer
pH 7.5
cryo-EM vitrification conditions
Cryogen ETHANE；Blot for 3 seconds using two pieces of filter paper, then plunge into liquid ethane (FEI VITROBOT MARK IV).
|
Resolution 5.00 Å
|
|
5A2Q
Structure of the HCV IRES bound to the human ribosome
Deposited 2015-05-21
|
Different oligomeric state
Different ligand/ion
Different experimental conditions
Different structure-quality metrics
|
Assembly 1
Protein–RNA
Heteromer；Protein × 36
PDB declaration: 38-meric
|
Chain N
1–151（151 aa）
|
Not recorded
|
MG MAGNESIUM ION × 98
ZN ZINC ION × 3
|
ELECTRON MICROSCOPY
cryo-EM buffer
20MM HEPES, 100 MM KCL, 5 MM MGCL2；pH 7.6；20MM HEPES, 100 MM KCL, 5 MM MGCL2
cryo-EM vitrification conditions
Cryogen ETHANE-PROPANE；FROZEN ON 200 MESH QUANTIFOIL R 2 2 HOLEY CARBON GRIDS WITH A THIN CONTINUOUS CARBON SUPPORT FILM APPLIED IN ETHANE PROPANE MIX
|
Resolution 3.90 Å
|
|
5AJ0
Cryo electron microscopy of actively translating human polysomes (POST state).
Deposited 2015-02-19
|
Different oligomeric state
Different ligand/ion
Different experimental conditions
Different structure-quality metrics
|
Assembly 1
Protein–RNA
Heteromer；Protein × 79
PDB declaration: 86-meric
|
Chain BN
1–151（151 aa）
|
Not recorded
|
MG MAGNESIUM ION × 326
ZN ZINC ION × 5
|
ELECTRON MICROSCOPY
cryo-EM buffer
20 MM HEPES-KOH, PH 7.5, 100 MM KCL, 1.5 MM MGCL2, 0.5 MM SPERMIDINE, 0.04 MM SPERMINE, 1 MM DTT；pH 7.5；20 MM HEPES-KOH, PH 7.5, 100 MM KCL, 1.5 MM MGCL2, 0.5 MM SPERMIDINE, 0.04 MM SPERMINE, 1 MM DTT
cryo-EM vitrification conditions
Cryogen ETHANE；VITRIFICATION 1 -- CRYOGEN- ETHANE, HUMIDITY- 100, TEMPERATURE- 93, INSTRUMENT- FEI VITROBOT MARK II, METHOD- BLOT FOR 2-4 SECONDS BEFORE PLUNGING,
|
Resolution 3.50 Å
|
|
5FLX
Mammalian 40S HCV-IRES complex
Deposited 2015-10-28
|
Different oligomeric state
Different ligand/ion
Different experimental conditions
Different structure-quality metrics
|
Assembly 1
Protein–RNA
Heteromer；Protein × 33
PDB declaration: 35-meric
|
Chain N
1–151（151 aa）
|
Not recorded
|
MG MAGNESIUM ION × 74
ZN ZINC ION × 2
|
ELECTRON MICROSCOPY
cryo-EM buffer
20MM TRIS-HCL, 7.5MM MGCL2, 100MM KCL, 0.2MM SPERMIDINE, 2MM DTT；pH 7.6；20MM TRIS-HCL, 7.5MM MGCL2, 100MM KCL, 0.2MM SPERMIDINE, 2MM DTT
cryo-EM vitrification conditions
Cryogen ETHANE；VITRIFICATION 1 -- CRYOGEN- ETHANE, HUMIDITY- 100, TEMPERATURE- 93, INSTRUMENT- FEI VITROBOT MARK I, METHOD- BLOT FOR 2-4 SECONDS BEFORE PLUNGING,
|
Resolution 3.90 Å
|
|
5LKS
Structure-function insights reveal the human ribosome as a cancer target for antibiotics
Deposited 2016-07-23
|
Different oligomeric state
Different ligand/ion
Different experimental conditions
Different structure-quality metrics
|
Assembly 1
Protein–RNA
Heteromer；Protein × 76
PDB declaration: 80-meric
|
Chain SN
1–151（151 aa）
|
Not recorded
|
3HE 4-{(2R)-2-[(1S,3S,5S)-3,5-dimethyl-2-oxocyclohexyl]-2-hydroxyethyl}piperidine-2,6-dione × 1
MG MAGNESIUM ION × 224
ZN ZINC ION × 8
|
ELECTRON MICROSCOPY
cryo-EM buffer
pH 7.5
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 3.60 Å
|
|
5OA3
Human 40S-eIF2D-re-initiation complex
Deposited 2017-06-20
|
Different oligomeric state
Different ligand/ion
Different experimental conditions
Different structure-quality metrics
|
Assembly 1
Protein–RNA
Heteromer；Protein × 35
PDB declaration: 38-meric
|
Chain N
1–151（151 aa）
|
Not recorded
|
ZN ZINC ION × 3
|
ELECTRON MICROSCOPY
cryo-EM buffer
pH 7.6
cryo-EM vitrification conditions
Cryogen ETHANE-PROPANE
|
Resolution 4.20 Å
R-free 0.325
|
|
5T2C
CryoEM structure of the human ribosome at 3.6 Angstrom resolution
Deposited 2016-08-23
|
Different oligomeric state
Different ligand/ion
Different experimental conditions
Different structure-quality metrics
|
Assembly 1
Protein–RNA
Heteromer；Protein × 76
PDB declaration: 81-meric
|
Chain AN
1–151（151 aa）
|
Not recorded
|
No recorded non-water small molecule
|
ELECTRON MICROSCOPY
cryo-EM buffer
pH 7.6
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 3.60 Å
|
|
5VYC
Crystal structure of the human 40S ribosomal subunit in complex with DENR-MCT-1.
Deposited 2017-05-24
|
Different oligomeric state
Different ligand/ion
Different experimental method
Different experimental conditions
Different structure-quality metrics
|
Assembly 1
Protein–RNA
Heteromer；Protein × 36
PDB declaration: 37-meric
|
Chain N1
1–151（151 aa）
|
Not recorded
|
ZN ZINC ION × 1
|
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 8.1；298.15 K；50 mM HEPES-NaOH, 50 mM NH4 acetate, 50 mM NH4Cl, 1 mM Mg acetate, 2 mM CaCl2, 3% PEG 20000, 3% PEG 3350, 2 mM TCEP, pH 8.1
|
Resolution 6.00 Å
R-free 0.321
|
|
5VYC
Crystal structure of the human 40S ribosomal subunit in complex with DENR-MCT-1.
Deposited 2017-05-24
|
Different oligomeric state
Different ligand/ion
Different experimental method
Different experimental conditions
Different structure-quality metrics
|
Assembly 2
Protein–RNA
Heteromer；Protein × 36
PDB declaration: 37-meric
|
Chain N2
1–151（151 aa）
|
Not recorded
|
ZN ZINC ION × 1
|
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 8.1；298.15 K；50 mM HEPES-NaOH, 50 mM NH4 acetate, 50 mM NH4Cl, 1 mM Mg acetate, 2 mM CaCl2, 3% PEG 20000, 3% PEG 3350, 2 mM TCEP, pH 8.1
|
Resolution 6.00 Å
R-free 0.321
|
|
5VYC
Crystal structure of the human 40S ribosomal subunit in complex with DENR-MCT-1.
Deposited 2017-05-24
|
Different oligomeric state
Different ligand/ion
Different experimental method
Different experimental conditions
Different structure-quality metrics
|
Assembly 3
Protein–RNA
Heteromer；Protein × 36
PDB declaration: 37-meric
|
Chain N3
1–151（151 aa）
|
Not recorded
|
ZN ZINC ION × 1
|
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 8.1；298.15 K；50 mM HEPES-NaOH, 50 mM NH4 acetate, 50 mM NH4Cl, 1 mM Mg acetate, 2 mM CaCl2, 3% PEG 20000, 3% PEG 3350, 2 mM TCEP, pH 8.1
|
Resolution 6.00 Å
R-free 0.321
|
|
5VYC
Crystal structure of the human 40S ribosomal subunit in complex with DENR-MCT-1.
Deposited 2017-05-24
|
Different oligomeric state
Different ligand/ion
Different experimental method
Different experimental conditions
Different structure-quality metrics
|
Assembly 4
Protein–RNA
Heteromer；Protein × 36
PDB declaration: 37-meric
|
Chain N4
1–151（151 aa）
|
Not recorded
|
ZN ZINC ION × 1
|
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 8.1；298.15 K；50 mM HEPES-NaOH, 50 mM NH4 acetate, 50 mM NH4Cl, 1 mM Mg acetate, 2 mM CaCl2, 3% PEG 20000, 3% PEG 3350, 2 mM TCEP, pH 8.1
|
Resolution 6.00 Å
R-free 0.321
|
|
5VYC
Crystal structure of the human 40S ribosomal subunit in complex with DENR-MCT-1.
Deposited 2017-05-24
|
Different oligomeric state
Different ligand/ion
Different experimental method
Different experimental conditions
Different structure-quality metrics
|
Assembly 5
Protein–RNA
Heteromer；Protein × 36
PDB declaration: 37-meric
|
Chain N5
1–151（151 aa）
|
Not recorded
|
ZN ZINC ION × 1
|
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 8.1；298.15 K；50 mM HEPES-NaOH, 50 mM NH4 acetate, 50 mM NH4Cl, 1 mM Mg acetate, 2 mM CaCl2, 3% PEG 20000, 3% PEG 3350, 2 mM TCEP, pH 8.1
|
Resolution 6.00 Å
R-free 0.321
|
|
5VYC
Crystal structure of the human 40S ribosomal subunit in complex with DENR-MCT-1.
Deposited 2017-05-24
|
Different oligomeric state
Different ligand/ion
Different experimental method
Different experimental conditions
Different structure-quality metrics
|
Assembly 6
Protein–RNA
Heteromer；Protein × 36
PDB declaration: 37-meric
|
Chain N6
1–151（151 aa）
|
Not recorded
|
ZN ZINC ION × 1
|
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 8.1；298.15 K；50 mM HEPES-NaOH, 50 mM NH4 acetate, 50 mM NH4Cl, 1 mM Mg acetate, 2 mM CaCl2, 3% PEG 20000, 3% PEG 3350, 2 mM TCEP, pH 8.1
|
Resolution 6.00 Å
R-free 0.321
|
|
6FEC
Human cap-dependent 48S pre-initiation complex
Deposited 2017-12-31
|
Different construct
Different oligomeric state
Different ligand/ion
Different experimental conditions
Different structure-quality metrics
|
Assembly 1
Protein–RNA
Heteromer；Protein × 47
PDB declaration: 50-meric
|
Chain Z
2–151（150 aa）
|
Not recorded
|
No recorded non-water small molecule
|
ELECTRON MICROSCOPY
cryo-EM buffer
pH 7.5；20 mM Tris HCl,
50 mM KOAc,
2.5 mM MgCl2,
2 mM DTT,
0.25 mM spermidine
0.25 mM GMPPNP
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 6.30 Å
|
|
6G18
Cryo-EM structure of a late human pre-40S ribosomal subunit - State C
Deposited 2018-03-20
|
Different oligomeric state
Different ligand/ion
Different experimental conditions
Different structure-quality metrics
|
Assembly 1
Protein–RNA
Heteromer；Protein × 34
PDB declaration: 35-meric
|
Chain N
1–151（151 aa）
|
Not recorded
|
ZN ZINC ION × 2
|
ELECTRON MICROSCOPY
cryo-EM buffer
pH 7.6
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 3.60 Å
|
|
6G4S
Cryo-EM structure of a late human pre-40S ribosomal subunit - State B
Deposited 2018-03-28
|
Different oligomeric state
Different ligand/ion
Different experimental conditions
Different structure-quality metrics
|
Assembly 1
Protein–RNA
Heteromer；Protein × 32
PDB declaration: 33-meric
|
Chain N
1–151（151 aa）
|
Not recorded
|
No recorded non-water small molecule
|
ELECTRON MICROSCOPY
cryo-EM buffer
pH 7.6
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 4.00 Å
|
|
6G4W
Cryo-EM structure of a late human pre-40S ribosomal subunit - State A
Deposited 2018-03-28
|
Different oligomeric state
Different ligand/ion
Different experimental conditions
Different structure-quality metrics
|
Assembly 1
Protein–RNA
Heteromer；Protein × 30
PDB declaration: 31-meric
|
Chain N
1–151（151 aa）
|
Not recorded
|
No recorded non-water small molecule
|
ELECTRON MICROSCOPY
cryo-EM buffer
pH 7.6
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 4.50 Å
|
|
6G51
Cryo-EM structure of a late human pre-40S ribosomal subunit - State D
Deposited 2018-03-28
|
Different oligomeric state
Different ligand/ion
Different experimental conditions
Different structure-quality metrics
|
Assembly 1
Protein–RNA
Heteromer；Protein × 37
PDB declaration: 38-meric
|
Chain N
1–151（151 aa）
|
Not recorded
|
No recorded non-water small molecule
|
ELECTRON MICROSCOPY
cryo-EM buffer
pH 7.6
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 4.10 Å
|
|
6G53
Cryo-EM structure of a late human pre-40S ribosomal subunit - State E
Deposited 2018-03-28
|
Different oligomeric state
Different ligand/ion
Different experimental conditions
Different structure-quality metrics
|
Assembly 1
Protein–RNA
Heteromer；Protein × 36
PDB declaration: 38-meric
|
Chain N
1–151（151 aa）
|
Not recorded
|
No recorded non-water small molecule
|
ELECTRON MICROSCOPY
cryo-EM buffer
pH 7.6
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 4.50 Å
|
|
6G5H
Cryo-EM structure of a late human pre-40S ribosomal subunit - Mature
Deposited 2018-03-29
|
Different oligomeric state
Different ligand/ion
Different experimental conditions
Different structure-quality metrics
|
Assembly 1
Protein–RNA
Heteromer；Protein × 34
PDB declaration: 35-meric
|
Chain N
1–151（151 aa）
|
Not recorded
|
ZN ZINC ION × 3
|
ELECTRON MICROSCOPY
cryo-EM buffer
pH 7.6
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 3.60 Å
|
|
6G5I
Cryo-EM structure of a late human pre-40S ribosomal subunit - State R
Deposited 2018-03-29
|
Different oligomeric state
Different ligand/ion
Different experimental conditions
Different structure-quality metrics
|
Assembly 1
Protein–RNA
Heteromer；Protein × 35
PDB declaration: 36-meric
|
Chain N
1–151（151 aa）
|
Not recorded
|
ZN ZINC ION × 3
|
ELECTRON MICROSCOPY
cryo-EM buffer
pH 7.6
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 3.50 Å
|
|
6IP5
Cryo-EM structure of the CMV-stalled human 80S ribosome (Structure ii)
Deposited 2018-11-02
|
Different oligomeric state
Different ligand/ion
Different experimental conditions
Different structure-quality metrics
|
Assembly 1
Protein–RNA
Heteromer；Protein × 77
PDB declaration: 84-meric
|
Chain 3K
1–151（151 aa）
|
Not recorded
|
No recorded non-water small molecule
|
ELECTRON MICROSCOPY
cryo-EM buffer
pH 7.5
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 3.90 Å
|
|
6IP6
Cryo-EM structure of the CMV-stalled human 80S ribosome with HCV IRES (Structure iii)
Deposited 2018-11-02
|
Different oligomeric state
Different ligand/ion
Different experimental conditions
Different structure-quality metrics
|
Assembly 1
Protein–RNA
Heteromer；Protein × 76
PDB declaration: 83-meric
|
Chain 3K
1–151（151 aa）
|
Not recorded
|
No recorded non-water small molecule
|
ELECTRON MICROSCOPY
cryo-EM buffer
pH 7.5
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 4.50 Å
|
|
6IP8
Cryo-EM structure of the HCV IRES dependently initiated CMV-stalled 80S ribosome (Structure iv)
Deposited 2018-11-02
|
Different oligomeric state
Different ligand/ion
Different experimental conditions
Different structure-quality metrics
|
Assembly 1
Protein–RNA
Heteromer；Protein × 77
PDB declaration: 84-meric
|
Chain 3K
1–151（151 aa）
|
Not recorded
|
No recorded non-water small molecule
|
ELECTRON MICROSCOPY
cryo-EM buffer
pH 7.5
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 3.90 Å
|
|
6OLE
Human ribosome nascent chain complex (CDH1-RNC) stalled by a drug-like molecule with AP and PE tRNAs
Deposited 2019-04-16
|
Different construct
Different oligomeric state
Different ligand/ion
Different experimental conditions
Different structure-quality metrics
|
Assembly 1
Protein–RNA
Heteromer；Protein × 76
PDB declaration: 83-meric
|
Chain SN
2–151（150 aa）
|
Not recorded
|
MG MAGNESIUM ION × 31
ZN ZINC ION × 6
MVM N-(3-chloropyridin-2-yl)-N-[(3R)-piperidin-3-yl]-4-(3H-[1,2,3]triazolo[4,5-b]pyridin-3-yl)benzamide × 1
|
ELECTRON MICROSCOPY
cryo-EM buffer
pH 7.5
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 3.10 Å
|
|
6OLF
Human ribosome nascent chain complex (CDH1-RNC) stalled by a drug-like molecule with AA and PE tRNAs
Deposited 2019-04-16
|
Different construct
Different oligomeric state
Different ligand/ion
Different experimental conditions
Different structure-quality metrics
|
Assembly 1
Protein–RNA
Heteromer；Protein × 76
PDB declaration: 83-meric
|
Chain SN
2–151（150 aa）
|
Not recorded
|
ZN ZINC ION × 6
MG MAGNESIUM ION × 31
MVM N-(3-chloropyridin-2-yl)-N-[(3R)-piperidin-3-yl]-4-(3H-[1,2,3]triazolo[4,5-b]pyridin-3-yl)benzamide × 1
|
ELECTRON MICROSCOPY
cryo-EM buffer
pH 7.5
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 3.90 Å
|
|
6OLG
Human ribosome nascent chain complex stalled by a drug-like small molecule (CDH1_RNC with PP tRNA)
Deposited 2019-04-16
|
Different construct
Different oligomeric state
Different ligand/ion
Different experimental conditions
|
Assembly 1
Protein–RNA
Heteromer；Protein × 79
PDB declaration: 85-meric
|
Chain BN
2–150（149 aa）
|
Not recorded
|
MG MAGNESIUM ION × 326
ZN ZINC ION × 5
MVM N-(3-chloropyridin-2-yl)-N-[(3R)-piperidin-3-yl]-4-(3H-[1,2,3]triazolo[4,5-b]pyridin-3-yl)benzamide × 1
|
ELECTRON MICROSCOPY
cryo-EM buffer
pH 7.5
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 3.40 Å
|
|
6OLI
Structure of human ribosome nascent chain complex selectively stalled by a drug-like small molecule (USO1-RNC)
Deposited 2019-04-16
|
Different construct
Different oligomeric state
Different ligand/ion
Different experimental conditions
Different structure-quality metrics
|
Assembly 1
Protein–RNA
Heteromer；Protein × 76
PDB declaration: 83-meric
|
Chain SN
2–151（150 aa）
|
Not recorded
|
MG MAGNESIUM ION × 31
ZN ZINC ION × 6
MVM N-(3-chloropyridin-2-yl)-N-[(3R)-piperidin-3-yl]-4-(3H-[1,2,3]triazolo[4,5-b]pyridin-3-yl)benzamide × 1
|
ELECTRON MICROSCOPY
cryo-EM buffer
pH 7.5
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 3.50 Å
|
|
6OLZ
Human ribosome nascent chain complex (PCSK9-RNC) stalled by a drug-like molecule with PP tRNA
Deposited 2019-04-17
|
Different construct
Different oligomeric state
Different ligand/ion
Different experimental conditions
Different structure-quality metrics
|
Assembly 1
Protein–RNA
Heteromer；Protein × 76
PDB declaration: 82-meric
|
Chain BN
2–150（149 aa）
|
Not recorded
|
MG MAGNESIUM ION × 326
ZN ZINC ION × 5
MVM N-(3-chloropyridin-2-yl)-N-[(3R)-piperidin-3-yl]-4-(3H-[1,2,3]triazolo[4,5-b]pyridin-3-yl)benzamide × 1
|
ELECTRON MICROSCOPY
cryo-EM buffer
pH 7.5
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 3.90 Å
|
|
6OM0
Human ribosome nascent chain complex (PCSK9-RNC) stalled by a drug-like molecule with AP and PE tRNAs
Deposited 2019-04-17
|
Different construct
Different oligomeric state
Different ligand/ion
Different experimental conditions
Different structure-quality metrics
|
Assembly 1
Protein–RNA
Heteromer；Protein × 76
PDB declaration: 83-meric
|
Chain SN
2–151（150 aa）
|
Not recorded
|
MG MAGNESIUM ION × 31
ZN ZINC ION × 6
MVM N-(3-chloropyridin-2-yl)-N-[(3R)-piperidin-3-yl]-4-(3H-[1,2,3]triazolo[4,5-b]pyridin-3-yl)benzamide × 1
|
ELECTRON MICROSCOPY
cryo-EM buffer
pH 7.5
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 3.10 Å
|
|
6OM7
Human ribosome nascent chain complex (PCSK9-RNC) stalled by a drug-like small molecule with AA and PE tRNAs
Deposited 2019-04-18
|
Different construct
Different oligomeric state
Different ligand/ion
Different experimental conditions
Different structure-quality metrics
|
Assembly 1
Protein–RNA
Heteromer；Protein × 76
PDB declaration: 83-meric
|
Chain SN
2–151（150 aa）
|
Not recorded
|
ZN ZINC ION × 6
MG MAGNESIUM ION × 31
MVM N-(3-chloropyridin-2-yl)-N-[(3R)-piperidin-3-yl]-4-(3H-[1,2,3]triazolo[4,5-b]pyridin-3-yl)benzamide × 1
|
ELECTRON MICROSCOPY
cryo-EM buffer
pH 7.5
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 3.70 Å
|
|
6QZP
High-resolution cryo-EM structure of the human 80S ribosome
Deposited 2019-03-12
|
Different construct
Different oligomeric state
Different ligand/ion
Different experimental conditions
Different structure-quality metrics
|
Assembly 1
Protein–RNA
Heteromer；Protein × 76
PDB declaration: 81-meric
|
Chain SN
2–151（150 aa）
|
Not recorded
|
MG MAGNESIUM ION × 438
HMT (3beta)-O~3~-[(2R)-2,6-dihydroxy-2-(2-methoxy-2-oxoethyl)-6-methylheptanoyl]cephalotaxine × 1
ZN ZINC ION × 8
HYG HYGROMYCIN B × 1
|
ELECTRON MICROSCOPY
cryo-EM buffer
pH 7.5
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 2.90 Å
|
|
6XA1
Structure of a drug-like compound stalled human translation termination complex
Deposited 2020-06-03
|
Different construct
Different oligomeric state
Different ligand/ion
Different experimental conditions
Different structure-quality metrics
|
Assembly 1
Protein–RNA
Heteromer；Protein × 77
PDB declaration: 83-meric
|
Chain SN
2–151（150 aa）
|
Not recorded
|
MG MAGNESIUM ION × 190
MVM N-(3-chloropyridin-2-yl)-N-[(3R)-piperidin-3-yl]-4-(3H-[1,2,3]triazolo[4,5-b]pyridin-3-yl)benzamide × 1
ZN ZINC ION × 8
K POTASSIUM ION × 2
|
ELECTRON MICROSCOPY
cryo-EM buffer
pH 7.6
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 2.80 Å
|
|
6Y0G
Structure of human ribosome in classical-PRE state
Deposited 2020-02-07
|
Different oligomeric state
Different ligand/ion
Different experimental conditions
Different structure-quality metrics
|
Assembly 1
Protein–RNA
Heteromer；Protein × 76
PDB declaration: 83-meric
|
Chain SN
1–151（151 aa）
|
Not recorded
|
MG MAGNESIUM ION × 72
3HE 4-{(2R)-2-[(1S,3S,5S)-3,5-dimethyl-2-oxocyclohexyl]-2-hydroxyethyl}piperidine-2,6-dione × 1
ZN ZINC ION × 7
|
ELECTRON MICROSCOPY
cryo-EM buffer
pH 7.6
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 3.20 Å
|
|
6Y2L
Structure of human ribosome in POST state
Deposited 2020-02-16
|
Different oligomeric state
Different ligand/ion
Different experimental conditions
Different structure-quality metrics
|
Assembly 1
Protein–RNA
Heteromer；Protein × 74
PDB declaration: 80-meric
|
Chain SN
1–151（151 aa）
|
Not recorded
|
MG MAGNESIUM ION × 193
3HE 4-{(2R)-2-[(1S,3S,5S)-3,5-dimethyl-2-oxocyclohexyl]-2-hydroxyethyl}piperidine-2,6-dione × 1
ZN ZINC ION × 7
|
ELECTRON MICROSCOPY
cryo-EM buffer
pH 7.6
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 3.00 Å
|
|
6Y57
Structure of human ribosome in hybrid-PRE state
Deposited 2020-02-25
|
Different oligomeric state
Different ligand/ion
Different experimental conditions
Different structure-quality metrics
|
Assembly 1
Protein–RNA
Heteromer；Protein × 75
PDB declaration: 82-meric
|
Chain SN
1–151（151 aa）
|
Not recorded
|
MG MAGNESIUM ION × 160
ZN ZINC ION × 7
|
ELECTRON MICROSCOPY
cryo-EM buffer
pH 7.6
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 3.50 Å
|
|
6YBD
Structure of a human 48S translational initiation complex - eIF3
Deposited 2020-03-16
|
Different oligomeric state
Different ligand/ion
Different experimental conditions
Different structure-quality metrics
|
Assembly 1
Protein heterocomplex
Heteromer；Protein × 19
PDB declaration: nonadecameric
|
Chain I
1–151（151 aa）
|
Not recorded
|
No recorded non-water small molecule
|
ELECTRON MICROSCOPY
cryo-EM buffer
pH 7.4
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 3.30 Å
|
|
6YBW
Structure of a human 48S translational initiation complex - 40S body
Deposited 2020-03-18
|
Different oligomeric state
Different ligand/ion
Different experimental conditions
Different structure-quality metrics
|
Assembly 1
Protein–RNA
Heteromer；Protein × 24
PDB declaration: 26-meric
|
Chain I
1–151（151 aa）
|
Not recorded
|
MG MAGNESIUM ION × 60
ZN ZINC ION × 1
|
ELECTRON MICROSCOPY
cryo-EM buffer
pH 7.4
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 3.10 Å
|
|
6Z6L
Cryo-EM structure of human CCDC124 bound to 80S ribosomes
Deposited 2020-05-28
|
Different oligomeric state
Different ligand/ion
Different experimental conditions
Different structure-quality metrics
|
Assembly 1
Protein–RNA
Heteromer；Protein × 78
PDB declaration: 83-meric
|
Chain SN
1–151（151 aa）
|
Not recorded
|
MG MAGNESIUM ION × 256
ZN ZINC ION × 8
|
ELECTRON MICROSCOPY
cryo-EM buffer
pH 7.4
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 3.00 Å
|
|
6Z6M
Cryo-EM structure of human 80S ribosomes bound to EBP1, eEF2 and SERBP1
Deposited 2020-05-28
|
Different oligomeric state
Different ligand/ion
Different experimental conditions
Different structure-quality metrics
|
Assembly 1
Protein–RNA
Heteromer；Protein × 79
PDB declaration: 84-meric
|
Chain SN
1–151（151 aa）
|
Not recorded
|
MG MAGNESIUM ION × 256
ZN ZINC ION × 8
|
ELECTRON MICROSCOPY
cryo-EM buffer
pH 7.4
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 3.10 Å
|
|
6Z6N
Cryo-EM structure of human EBP1-80S ribosomes (focus on EBP1)
Deposited 2020-05-28
|
Different oligomeric state
Different ligand/ion
Different experimental conditions
Different structure-quality metrics
|
Assembly 1
Protein–RNA
Heteromer；Protein × 79
PDB declaration: 84-meric
|
Chain SN
1–151（151 aa）
|
Not recorded
|
MG MAGNESIUM ION × 256
ZN ZINC ION × 8
|
ELECTRON MICROSCOPY
cryo-EM buffer
pH 7.4
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 2.90 Å
|
|
6ZLW
SARS-CoV-2 Nsp1 bound to the human 40S ribosomal subunit
Deposited 2020-07-01
|
Different oligomeric state
Different ligand/ion
Different experimental conditions
Different structure-quality metrics
|
Assembly 1
Protein–RNA
Heteromer；Protein × 35
PDB declaration: 36-meric
|
Chain N
1–151（151 aa）
|
Not recorded
|
ZN ZINC ION × 3
|
ELECTRON MICROSCOPY
cryo-EM buffer
pH 7.5
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 2.60 Å
|
|
6ZM7
SARS-CoV-2 Nsp1 bound to the human CCDC124-80S-EBP1 ribosome complex
Deposited 2020-07-01
|
Different oligomeric state
Different ligand/ion
Different experimental conditions
Different structure-quality metrics
|
Assembly 1
Protein–RNA
Heteromer；Protein × 81
PDB declaration: 86-meric
|
Chain SN
1–151（151 aa）
|
Not recorded
|
MG MAGNESIUM ION × 256
ZN ZINC ION × 8
|
ELECTRON MICROSCOPY
cryo-EM buffer
pH 7.5
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 2.70 Å
|
|
6ZME
SARS-CoV-2 Nsp1 bound to the human CCDC124-80S-eERF1 ribosome complex
Deposited 2020-07-02
|
Different oligomeric state
Different ligand/ion
Different experimental conditions
Different structure-quality metrics
|
Assembly 1
Protein–RNA
Heteromer；Protein × 83
PDB declaration: 88-meric
|
Chain SN
1–151（151 aa）
|
Not recorded
|
MG MAGNESIUM ION × 256
ZN ZINC ION × 8
SF4 IRON/SULFUR CLUSTER × 2
ADP ADENOSINE-5'-DIPHOSPHATE × 1
|
ELECTRON MICROSCOPY
cryo-EM buffer
pH 7.5
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 3.00 Å
|
|
6ZMI
SARS-CoV-2 Nsp1 bound to the human LYAR-80S ribosome complex
Deposited 2020-07-02
|
Different oligomeric state
Different ligand/ion
Different experimental conditions
Different structure-quality metrics
|
Assembly 1
Protein–RNA
Heteromer；Protein × 81
PDB declaration: 86-meric
|
Chain SN
1–151（151 aa）
|
Not recorded
|
MG MAGNESIUM ION × 256
ZN ZINC ION × 8
|
ELECTRON MICROSCOPY
cryo-EM buffer
pH 7.5
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 2.60 Å
|
|
6ZMO
SARS-CoV-2 Nsp1 bound to the human LYAR-80S-eEF1a ribosome complex
Deposited 2020-07-03
|
Different oligomeric state
Different ligand/ion
Different experimental conditions
Different structure-quality metrics
|
Assembly 1
Protein–RNA
Heteromer；Protein × 82
PDB declaration: 88-meric
|
Chain SN
1–151（151 aa）
|
Not recorded
|
MG MAGNESIUM ION × 256
ZN ZINC ION × 8
|
ELECTRON MICROSCOPY
cryo-EM buffer
pH 7.5
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 3.10 Å
|
|
6ZMT
SARS-CoV-2 Nsp1 bound to a pre-40S-like ribosome complex
Deposited 2020-07-03
|
Different oligomeric state
Different ligand/ion
Different experimental conditions
Different structure-quality metrics
|
Assembly 1
Protein–RNA
Heteromer；Protein × 34
PDB declaration: 35-meric
|
Chain N
1–151（151 aa）
|
Not recorded
|
ZN ZINC ION × 2
|
ELECTRON MICROSCOPY
cryo-EM buffer
pH 7.5
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 3.00 Å
|
|
6ZMW
Structure of a human 48S translational initiation complex
Deposited 2020-07-04
|
Different oligomeric state
Different ligand/ion
Different experimental conditions
Different structure-quality metrics
|
Assembly 1
Protein–RNA
Heteromer；Protein × 54
PDB declaration: 57-meric
|
Chain I
1–151（151 aa）
|
Not recorded
|
ZN ZINC ION × 2
MG MAGNESIUM ION × 89
|
ELECTRON MICROSCOPY
cryo-EM buffer
pH 7.4
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 3.70 Å
|
|
6ZN5
SARS-CoV-2 Nsp1 bound to a pre-40S-like ribosome complex - state 2
Deposited 2020-07-06
|
Different construct
Different oligomeric state
Different ligand/ion
Different experimental conditions
Different structure-quality metrics
|
Assembly 1
Protein–RNA
Heteromer；Protein × 35
PDB declaration: 36-meric
|
Chain N
2–150（149 aa）
|
Not recorded
|
ZN ZINC ION × 3
|
ELECTRON MICROSCOPY
cryo-EM buffer
pH 7.5
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 3.20 Å
|
|
6ZOJ
SARS-CoV-2-Nsp1-40S complex, composite map
Deposited 2020-07-07
|
Different oligomeric state
Different ligand/ion
Different experimental conditions
Different structure-quality metrics
|
Assembly 1
Protein–RNA
Heteromer；Protein × 35
PDB declaration: 36-meric
|
Chain N
1–151（151 aa）
|
Not recorded
|
MG MAGNESIUM ION × 166
ZN ZINC ION × 3
|
ELECTRON MICROSCOPY
cryo-EM buffer
pH 7.6
cryo-EM vitrification conditions
Cryogen ETHANE-PROPANE
|
Resolution 2.80 Å
|
|
6ZOK
SARS-CoV-2-Nsp1-40S complex, focused on body
Deposited 2020-07-07
|
Different oligomeric state
Different ligand/ion
Different experimental conditions
Different structure-quality metrics
|
Assembly 1
Protein–RNA
Heteromer；Protein × 21
PDB declaration: 22-meric
|
Chain N
1–151（151 aa）
|
Not recorded
|
MG MAGNESIUM ION × 109
ZN ZINC ION × 1
|
ELECTRON MICROSCOPY
cryo-EM buffer
pH 7.6
cryo-EM vitrification conditions
Cryogen ETHANE-PROPANE
|
Resolution 2.80 Å
|
|
6ZON
SARS-CoV-2 Nsp1 bound to a human 43S preinitiation ribosome complex - state 1
Deposited 2020-07-07
|
Different oligomeric state
Different ligand/ion
Different experimental conditions
Different structure-quality metrics
|
Assembly 1
Protein–RNA
Heteromer；Protein × 47
PDB declaration: 48-meric
|
Chain m
1–151（151 aa）
|
Not recorded
|
ZN ZINC ION × 3
|
ELECTRON MICROSCOPY
cryo-EM buffer
pH 7.5
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 3.00 Å
|
|
6ZP4
SARS-CoV-2 Nsp1 bound to a human 43S preinitiation ribosome complex - state 2
Deposited 2020-07-08
|
Different oligomeric state
Different ligand/ion
Different experimental conditions
Different structure-quality metrics
|
Assembly 1
Protein–RNA
Heteromer；Protein × 52
PDB declaration: 54-meric
|
Chain m
1–151（151 aa）
|
Not recorded
|
ZN ZINC ION × 4
GTP GUANOSINE-5'-TRIPHOSPHATE × 1
MG MAGNESIUM ION × 1
|
ELECTRON MICROSCOPY
cryo-EM buffer
pH 7.5
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 2.90 Å
|
|
6ZUO
Human RIO1(kd)-StHA late pre-40S particle, structural state A (pre 18S rRNA cleavage)
Deposited 2020-07-23
|
Different oligomeric state
Different ligand/ion
Different experimental conditions
Different structure-quality metrics
|
Assembly 1
Protein–RNA
Heteromer；Protein × 34
PDB declaration: 35-meric
|
Chain N
1–151（151 aa）
|
Not recorded
|
ZN ZINC ION × 3
|
ELECTRON MICROSCOPY
cryo-EM buffer
pH 7.6
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 3.10 Å
|
|
6ZV6
Human RIO1(kd)-StHA late pre-40S particle, structural state B (post 18S rRNA cleavage)
Deposited 2020-07-24
|
Different oligomeric state
Different ligand/ion
Different experimental conditions
Different structure-quality metrics
|
Assembly 1
Protein–RNA
Heteromer；Protein × 34
PDB declaration: 35-meric
|
Chain N
1–151（151 aa）
|
Not recorded
|
MG MAGNESIUM ION × 3
ZN ZINC ION × 1
ADP ADENOSINE-5'-DIPHOSPHATE × 1
|
ELECTRON MICROSCOPY
cryo-EM buffer
pH 7.6
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 2.90 Å
|
|
6ZVH
EDF1-ribosome complex
Deposited 2020-07-24
|
Different construct
Different oligomeric state
Different ligand/ion
Different experimental conditions
Different structure-quality metrics
|
Assembly 1
Protein–RNA
Heteromer；Protein × 35
PDB declaration: 37-meric
|
Chain N
2–151（150 aa）
|
Not recorded
|
MG MAGNESIUM ION × 30
ZN ZINC ION × 3
|
ELECTRON MICROSCOPY
cryo-EM buffer
pH 7.5
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 2.90 Å
|
|
6ZVJ
Structure of a human ABCE1-bound 43S pre-initiation complex - State II
Deposited 2020-07-24
|
Different construct
Different oligomeric state
Different ligand/ion
Different experimental conditions
Different structure-quality metrics
|
Assembly 1
Protein–RNA
Heteromer；Protein × 50
PDB declaration: 51-meric
|
Chain m
2–150（149 aa）
|
Not recorded
|
ZN ZINC ION × 3
SF4 IRON/SULFUR CLUSTER × 2
ADP ADENOSINE-5'-DIPHOSPHATE × 1
MG MAGNESIUM ION × 2
ATP ADENOSINE-5'-TRIPHOSPHATE × 1
|
ELECTRON MICROSCOPY
cryo-EM buffer
pH 7.6
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 3.80 Å
|
|
6ZXD
Cryo-EM structure of a late human pre-40S ribosomal subunit - State F1
Deposited 2020-07-29
|
Different oligomeric state
Different ligand/ion
Different experimental conditions
Different structure-quality metrics
|
Assembly 1
Protein–RNA
Heteromer；Protein × 36
PDB declaration: 37-meric
|
Chain N
1–151（151 aa）
|
Not recorded
|
ZN ZINC ION × 2
|
ELECTRON MICROSCOPY
cryo-EM buffer
pH 7.6
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 3.20 Å
|
|
6ZXE
Cryo-EM structure of a late human pre-40S ribosomal subunit - State F2
Deposited 2020-07-29
|
Different oligomeric state
Different ligand/ion
Different experimental conditions
Different structure-quality metrics
|
Assembly 1
Protein–RNA
Heteromer；Protein × 36
PDB declaration: 37-meric
|
Chain N
1–151（151 aa）
|
Not recorded
|
ZN ZINC ION × 2
|
ELECTRON MICROSCOPY
cryo-EM buffer
pH 7.6
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 3.00 Å
|
|
6ZXF
Cryo-EM structure of a late human pre-40S ribosomal subunit - State G
Deposited 2020-07-29
|
Different oligomeric state
Different ligand/ion
Different experimental conditions
Different structure-quality metrics
|
Assembly 1
Protein–RNA
Heteromer；Protein × 36
PDB declaration: 37-meric
|
Chain N
1–151（151 aa）
|
Not recorded
|
ZN ZINC ION × 3
MG MAGNESIUM ION × 2
ATP ADENOSINE-5'-TRIPHOSPHATE × 1
|
ELECTRON MICROSCOPY
cryo-EM buffer
pH 7.6
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 3.70 Å
|
|
6ZXG
Cryo-EM structure of a late human pre-40S ribosomal subunit - State H1
Deposited 2020-07-29
|
Different oligomeric state
Different ligand/ion
Different experimental conditions
Different structure-quality metrics
|
Assembly 1
Protein–RNA
Heteromer；Protein × 36
PDB declaration: 37-meric
|
Chain N
1–151（151 aa）
|
Not recorded
|
MG MAGNESIUM ION × 131
ZN ZINC ION × 3
ASP ASPARTIC ACID × 1
ATP ADENOSINE-5'-TRIPHOSPHATE × 1
|
ELECTRON MICROSCOPY
cryo-EM buffer
pH 7.6
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 2.60 Å
|
|
6ZXH
Cryo-EM structure of a late human pre-40S ribosomal subunit - State H2
Deposited 2020-07-29
|
Different oligomeric state
Different ligand/ion
Different experimental conditions
Different structure-quality metrics
|
Assembly 1
Protein–RNA
Heteromer；Protein × 35
PDB declaration: 36-meric
|
Chain N
1–151（151 aa）
|
Not recorded
|
ASP ASPARTIC ACID × 1
MG MAGNESIUM ION × 131
ZN ZINC ION × 3
ATP ADENOSINE-5'-TRIPHOSPHATE × 1
|
ELECTRON MICROSCOPY
cryo-EM buffer
pH 7.6
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 2.70 Å
|
|
7A09
Structure of a human ABCE1-bound 43S pre-initiation complex - State III
Deposited 2020-08-07
|
Different oligomeric state
Different ligand/ion
Different experimental conditions
Different structure-quality metrics
|
Assembly 1
Protein–RNA
Heteromer；Protein × 52
PDB declaration: 54-meric
|
Chain m
1–151（151 aa）
|
Not recorded
|
ZN ZINC ION × 4
SF4 IRON/SULFUR CLUSTER × 2
ADP ADENOSINE-5'-DIPHOSPHATE × 1
MG MAGNESIUM ION × 3
ATP ADENOSINE-5'-TRIPHOSPHATE × 1
MET METHIONINE × 1
GTP GUANOSINE-5'-TRIPHOSPHATE × 1
|
ELECTRON MICROSCOPY
cryo-EM buffer
pH 7.6
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 3.50 Å
|
|
7K5I
SARS-COV-2 nsp1 in complex with human 40S ribosome
Deposited 2020-09-16
|
Different oligomeric state
Different ligand/ion
Different experimental conditions
Different structure-quality metrics
|
Assembly 1
Protein–RNA
Heteromer；Protein × 35
PDB declaration: 36-meric
|
Chain N
1–151（151 aa）
|
Not recorded
|
MG MAGNESIUM ION × 1
ZN ZINC ION × 3
|
ELECTRON MICROSCOPY
cryo-EM buffer
pH 7.4
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 2.90 Å
|
|
7MQ8
Cryo-EM structure of the human SSU processome, state pre-A1
Deposited 2021-05-05
|
Different oligomeric state
Different ligand/ion
Different experimental conditions
Different structure-quality metrics
|
Assembly 1
Protein–RNA
Heteromer；Protein × 71
PDB declaration: 75-meric
|
Chain NF
1–151（151 aa）
|
Not recorded
|
MG MAGNESIUM ION × 22
ATP ADENOSINE-5'-TRIPHOSPHATE × 2
ZN ZINC ION × 3
GTP GUANOSINE-5'-TRIPHOSPHATE × 1
SAH S-ADENOSYL-L-HOMOCYSTEINE × 2
|
ELECTRON MICROSCOPY
cryo-EM buffer
pH 7.6
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 3.60 Å
|
|
7MQ9
Cryo-EM structure of the human SSU processome, state pre-A1*
Deposited 2021-05-05
|
Different oligomeric state
Different ligand/ion
Different experimental conditions
Different structure-quality metrics
|
Assembly 1
Protein–RNA
Heteromer；Protein × 70
PDB declaration: 74-meric
|
Chain NF
1–151（151 aa）
|
Not recorded
|
MG MAGNESIUM ION × 22
ZN ZINC ION × 3
GTP GUANOSINE-5'-TRIPHOSPHATE × 1
SAH S-ADENOSYL-L-HOMOCYSTEINE × 2
ATP ADENOSINE-5'-TRIPHOSPHATE × 2
|
ELECTRON MICROSCOPY
cryo-EM buffer
pH 7.6
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 3.87 Å
|
|
7MQA
Cryo-EM structure of the human SSU processome, state post-A1
Deposited 2021-05-05
|
Different oligomeric state
Different ligand/ion
Different experimental conditions
Different structure-quality metrics
|
Assembly 1
Protein–RNA
Heteromer；Protein × 69
PDB declaration: 72-meric
|
Chain NF
1–151（151 aa）
|
Not recorded
|
MG MAGNESIUM ION × 64
ATP ADENOSINE-5'-TRIPHOSPHATE × 1
ZN ZINC ION × 3
GTP GUANOSINE-5'-TRIPHOSPHATE × 1
SAH S-ADENOSYL-L-HOMOCYSTEINE × 2
|
ELECTRON MICROSCOPY
cryo-EM buffer
pH 7.6
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 2.70 Å
|
|
7QP6
Structure of the human 48S initiation complex in open state (h48S AUG open)
Deposited 2022-01-03
|
Different oligomeric state
Different ligand/ion
Different experimental conditions
Different structure-quality metrics
|
Assembly 1
Protein–RNA
Heteromer；Protein × 50
PDB declaration: 53-meric
|
Chain I
1–151（151 aa）
|
Not recorded
|
ZN ZINC ION × 2
MG MAGNESIUM ION × 2
|
ELECTRON MICROSCOPY
cryo-EM buffer
pH 7.5；20 mM Hepes, pH 7.5,
95 mM KOAc, 3.75 mM Mg(OAc)2, 1 mM ATP, 0.5 mM GTP, 0.25 mM spermidine, 2 mM DTT,
0.4 U/uL RiboLock RNase inhibitor
cryo-EM vitrification conditions
Cryogen ETHANE；Cryo-EM grids were prepared by
floating home-made continuous carbon on 40 ul sample in the wells of teflon block (custom-made). The sample-covered carbon was then adsorbed to an EM grid.
|
Resolution 4.70 Å
|
|
7QP7
Structure of the human 48S initiation complex in closed state (h48S AUG closed)
Deposited 2022-01-03
|
Different oligomeric state
Different ligand/ion
Different experimental conditions
Different structure-quality metrics
|
Assembly 1
Protein–RNA
Heteromer；Protein × 48
PDB declaration: 51-meric
|
Chain I
1–151（151 aa）
|
Not recorded
|
ZN ZINC ION × 2
|
ELECTRON MICROSCOPY
cryo-EM buffer
pH 7.5；20 mM Hepes, pH 7.5,
95 mM KOAc, 3.75 mM Mg(OAc)2, 1 mM ATP, 0.5 mM GTP, 0.25 mM spermidine, 2 mM DTT,
0.4 U/uL RiboLock RNase inhibitor
cryo-EM vitrification conditions
Cryogen ETHANE；Cryo-EM grids were prepared by
floating home-made continuous carbon on 40 ul sample in the wells of teflon block (custom-made). The sample-covered carbon was then adsorbed to an EM grid.
|
Resolution 3.70 Å
|
|
7R4X
Cryo-EM reconstruction of the human 40S ribosomal subunit - Full map
Deposited 2022-02-09
|
Different oligomeric state
Different ligand/ion
Different experimental conditions
Different structure-quality metrics
|
Assembly 1
Protein–RNA
Heteromer；Protein × 34
PDB declaration: 35-meric
|
Chain N
1–151（151 aa）
|
Not recorded
|
K POTASSIUM ION × 82
MG MAGNESIUM ION × 88
ZN ZINC ION × 3
|
ELECTRON MICROSCOPY
cryo-EM buffer
pH 7.5
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 2.15 Å
|
|
7WTS
Cryo-EM structure of a human pre-40S ribosomal subunit - State UTP14
Deposited 2022-02-05
|
Different oligomeric state
Different ligand/ion
Different experimental conditions
Different structure-quality metrics
|
Assembly 1
Protein–RNA
Heteromer；Protein × 22
PDB declaration: 23-meric
|
Chain N
1–151（151 aa）
|
Not recorded
|
No recorded non-water small molecule
|
ELECTRON MICROSCOPY
cryo-EM buffer
pH 7.4
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 3.20 Å
|
|
7WTT
Cryo-EM structure of a human pre-40S ribosomal subunit - State RRP12-A1 (with CK1)
Deposited 2022-02-05
|
Different oligomeric state
Different ligand/ion
Different experimental conditions
Different structure-quality metrics
|
Assembly 1
Protein–RNA
Heteromer；Protein × 33
PDB declaration: 34-meric
|
Chain N
1–151（151 aa）
|
Not recorded
|
SAH S-ADENOSYL-L-HOMOCYSTEINE × 1
ZN ZINC ION × 1
|
ELECTRON MICROSCOPY
cryo-EM buffer
pH 7.4
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 3.10 Å
|
|
7WTU
Cryo-EM structure of a human pre-40S ribosomal subunit - State RRP12-A1 (without CK1)
Deposited 2022-02-05
|
Different oligomeric state
Different ligand/ion
Different experimental conditions
Different structure-quality metrics
|
Assembly 1
Protein–RNA
Heteromer；Protein × 32
PDB declaration: 33-meric
|
Chain N
1–151（151 aa）
|
Not recorded
|
SAH S-ADENOSYL-L-HOMOCYSTEINE × 1
ZN ZINC ION × 1
|
ELECTRON MICROSCOPY
cryo-EM buffer
pH 7.4
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 3.00 Å
|
|
7WTV
Cryo-EM structure of a human pre-40S ribosomal subunit - State RRP12-A2
Deposited 2022-02-05
|
Different oligomeric state
Different ligand/ion
Different experimental conditions
Different structure-quality metrics
|
Assembly 1
Protein–RNA
Heteromer；Protein × 34
PDB declaration: 35-meric
|
Chain N
1–151（151 aa）
|
Not recorded
|
ZN ZINC ION × 1
SAH S-ADENOSYL-L-HOMOCYSTEINE × 1
|
ELECTRON MICROSCOPY
cryo-EM buffer
pH 7.4
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 3.50 Å
|
|
7WTW
Cryo-EM structure of a human pre-40S ribosomal subunit - State RRP12-A3
Deposited 2022-02-05
|
Different oligomeric state
Different ligand/ion
Different experimental conditions
Different structure-quality metrics
|
Assembly 1
Protein–RNA
Heteromer；Protein × 36
PDB declaration: 37-meric
|
Chain N
1–151（151 aa）
|
Not recorded
|
ZN ZINC ION × 2
|
ELECTRON MICROSCOPY
cryo-EM buffer
pH 7.4
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 3.20 Å
|
|
7WTX
Cryo-EM structure of a human pre-40S ribosomal subunit - State RRP12-B1
Deposited 2022-02-05
|
Different oligomeric state
Different ligand/ion
Different experimental conditions
Different structure-quality metrics
|
Assembly 1
Protein–RNA
Heteromer；Protein × 33
PDB declaration: 34-meric
|
Chain N
1–151（151 aa）
|
Not recorded
|
ZN ZINC ION × 2
|
ELECTRON MICROSCOPY
cryo-EM buffer
pH 7.4
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 3.10 Å
|
|
7WTZ
Cryo-EM structure of a human pre-40S ribosomal subunit - State RRP12-B2
Deposited 2022-02-05
|
Different oligomeric state
Different ligand/ion
Different experimental conditions
Different structure-quality metrics
|
Assembly 1
Protein–RNA
Heteromer；Protein × 33
PDB declaration: 34-meric
|
Chain N
1–151（151 aa）
|
Not recorded
|
ZN ZINC ION × 2
|
ELECTRON MICROSCOPY
cryo-EM buffer
pH 7.4
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 3.00 Å
|
|
7WU0
Cryo-EM structure of a human pre-40S ribosomal subunit - State RRP12-B3
Deposited 2022-02-05
|
Different oligomeric state
Different ligand/ion
Different experimental conditions
Different structure-quality metrics
|
Assembly 1
Protein–RNA
Heteromer；Protein × 34
PDB declaration: 35-meric
|
Chain N
1–151（151 aa）
|
Not recorded
|
ZN ZINC ION × 2
|
ELECTRON MICROSCOPY
cryo-EM buffer
pH 7.4
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 3.30 Å
|
|
7XNX
High resolution cry-EM structure of the human 80S ribosome from SNORD127+/+ Kasumi-1 cells
Deposited 2022-04-30
|
Different oligomeric state
Different ligand/ion
Different experimental conditions
Different structure-quality metrics
|
Assembly 1
Protein–RNA
Heteromer；Protein × 76
PDB declaration: 81-meric
|
Chain SN
1–151（151 aa）
|
Not recorded
|
MG MAGNESIUM ION × 421
K POTASSIUM ION × 12
ZN ZINC ION × 9
|
ELECTRON MICROSCOPY
cryo-EM buffer
pH 7.4
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 2.70 Å
|
|
7XNY
High resolution cry-EM structure of the human 80S ribosome from SNORD127+/- Kasumi-1 cells
Deposited 2022-04-30
|
Different oligomeric state
Different ligand/ion
Different experimental conditions
Different structure-quality metrics
|
Assembly 1
Protein–RNA
Heteromer；Protein × 75
PDB declaration: 79-meric
|
Chain SN
1–151（151 aa）
|
Not recorded
|
MG MAGNESIUM ION × 421
K POTASSIUM ION × 12
ZN ZINC ION × 9
|
ELECTRON MICROSCOPY
cryo-EM buffer
pH 7.4
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 2.50 Å
|
|
8G5Y
mRNA decoding in human is kinetically and structurally distinct from bacteria (IC state)
Deposited 2023-02-14
|
Different oligomeric state
Different ligand/ion
Different experimental conditions
Different structure-quality metrics
|
Assembly 1
Protein–RNA
Heteromer；Protein × 77
PDB declaration: 83-meric
|
Chain SN
1–151（151 aa）
|
Not recorded
|
SPD SPERMIDINE × 13
PUT 1,4-DIAMINOBUTANE × 11
K POTASSIUM ION × 77
MG MAGNESIUM ION × 524
ANM ANISOMYCIN × 1
3H3 4-{(2R,5S,6E)-2-hydroxy-5-methyl-7-[(2R,3S,4E,6Z,10E)-3-methyl-12-oxooxacyclododeca-4,6,10-trien-2-yl]-4-oxooct-6-en-1-yl}piperidine-2,6-dione × 1
ZN ZINC ION × 8
MET METHIONINE × 1
|
ELECTRON MICROSCOPY
cryo-EM buffer
pH 7
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 2.29 Å
|
|
8G5Z
mRNA decoding in human is kinetically and structurally distinct from bacteria (GA state)
Deposited 2023-02-14
|
Different construct
Different oligomeric state
Different ligand/ion
Different experimental conditions
Different structure-quality metrics
|
Assembly 1
Protein–RNA
Heteromer；Protein × 80
PDB declaration: 87-meric
|
Chain SN
2–151（150 aa）
|
Not recorded
|
SPD SPERMIDINE × 10
K POTASSIUM ION × 45
MG MAGNESIUM ION × 433
ANM ANISOMYCIN × 1
PUT 1,4-DIAMINOBUTANE × 8
3H3 4-{(2R,5S,6E)-2-hydroxy-5-methyl-7-[(2R,3S,4E,6Z,10E)-3-methyl-12-oxooxacyclododeca-4,6,10-trien-2-yl]-4-oxooct-6-en-1-yl}piperidine-2,6-dione × 1
ZN ZINC ION × 8
PHE PHENYLALANINE × 1
MET METHIONINE × 1
GSP 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE × 1
ZIY plitidepsin × 1
|
ELECTRON MICROSCOPY
cryo-EM buffer
pH 7.5
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 2.64 Å
|
|
8G60
mRNA decoding in human is kinetically and structurally distinct from bacteria (CR state)
Deposited 2023-02-14
|
Different oligomeric state
Different ligand/ion
Different experimental conditions
Different structure-quality metrics
|
Assembly 1
Protein–RNA
Heteromer；Protein × 79
PDB declaration: 86-meric
|
Chain SN
1–151（151 aa）
|
Not recorded
|
SPD SPERMIDINE × 8
PUT 1,4-DIAMINOBUTANE × 10
MG MAGNESIUM ION × 461
ANM ANISOMYCIN × 1
3H3 4-{(2R,5S,6E)-2-hydroxy-5-methyl-7-[(2R,3S,4E,6Z,10E)-3-methyl-12-oxooxacyclododeca-4,6,10-trien-2-yl]-4-oxooct-6-en-1-yl}piperidine-2,6-dione × 1
K POTASSIUM ION × 10
ZN ZINC ION × 7
PHE PHENYLALANINE × 1
MET METHIONINE × 1
GSP 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE × 1
ZIY plitidepsin × 1
|
ELECTRON MICROSCOPY
cryo-EM buffer
pH 7
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 2.54 Å
|
|
8G61
mRNA decoding in human is kinetically and structurally distinct from bacteria (AC state)
Deposited 2023-02-14
|
Different oligomeric state
Different ligand/ion
Different experimental conditions
Different structure-quality metrics
|
Assembly 1
Protein–RNA
Heteromer；Protein × 77
PDB declaration: 84-meric
|
Chain SN
1–151（151 aa）
|
Not recorded
|
PUT 1,4-DIAMINOBUTANE × 4
K POTASSIUM ION × 16
MG MAGNESIUM ION × 326
ANM ANISOMYCIN × 1
SPD SPERMIDINE × 5
3H3 4-{(2R,5S,6E)-2-hydroxy-5-methyl-7-[(2R,3S,4E,6Z,10E)-3-methyl-12-oxooxacyclododeca-4,6,10-trien-2-yl]-4-oxooct-6-en-1-yl}piperidine-2,6-dione × 1
ZN ZINC ION × 8
MET METHIONINE × 1
|
ELECTRON MICROSCOPY
cryo-EM buffer
pH 7
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 2.94 Å
|
|
8G6J
mRNA decoding in human is kinetically and structurally distinct from bacteria (GA state 2)
Deposited 2023-02-15
|
Different oligomeric state
Different ligand/ion
Different experimental conditions
Different structure-quality metrics
|
Assembly 1
Protein–RNA
Heteromer；Protein × 79
PDB declaration: 86-meric
|
Chain SN
1–151（151 aa）
|
Not recorded
|
SPD SPERMIDINE × 10
K POTASSIUM ION × 34
MG MAGNESIUM ION × 337
PUT 1,4-DIAMINOBUTANE × 8
3HE 4-{(2R)-2-[(1S,3S,5S)-3,5-dimethyl-2-oxocyclohexyl]-2-hydroxyethyl}piperidine-2,6-dione × 1
HMT (3beta)-O~3~-[(2R)-2,6-dihydroxy-2-(2-methoxy-2-oxoethyl)-6-methylheptanoyl]cephalotaxine × 1
ZN ZINC ION × 8
PHE PHENYLALANINE × 1
MET METHIONINE × 1
GSP 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE × 1
YRB (3R,6R,9S,12S,15S,18S,20R,24aR)-6-[(2S)-butan-2-yl]-3,12-bis[(1R)-1-hydroxy-2-methylpropyl]-8,9,11,17,18-pentamethyl-15-[(2S)-2-methylbutyl]hexadecahydropyrido[1,2-a][1,4,7,10,13,16,19]heptaazacyclohenicosine-1,4,7,10,13,16,19(21H)-heptone × 1
|
ELECTRON MICROSCOPY
cryo-EM buffer
pH 7
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 2.80 Å
|
|
8GLP
mRNA decoding in human is kinetically and structurally distinct from bacteria (Consensus LSU focused refined structure)
Deposited 2023-03-22
|
Different oligomeric state
Different ligand/ion
Different experimental conditions
Different structure-quality metrics
|
Assembly 1
Protein–RNA
Heteromer；Protein × 75
PDB declaration: 81-meric
|
Chain SN
1–151（151 aa）
|
Not recorded
|
SPD SPERMIDINE × 15
PUT 1,4-DIAMINOBUTANE × 9
K POTASSIUM ION × 152
MG MAGNESIUM ION × 671
ANM ANISOMYCIN × 1
3H3 4-{(2R,5S,6E)-2-hydroxy-5-methyl-7-[(2R,3S,4E,6Z,10E)-3-methyl-12-oxooxacyclododeca-4,6,10-trien-2-yl]-4-oxooct-6-en-1-yl}piperidine-2,6-dione × 1
TRS 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL × 2
ZN ZINC ION × 8
MET METHIONINE × 1
|
ELECTRON MICROSCOPY
cryo-EM buffer
pH 7
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 1.67 Å
|
|
8IFD
Dibekacin-added human 80S ribosome
Deposited 2023-02-17
|
Different oligomeric state
Different ligand/ion
Different experimental conditions
Different structure-quality metrics
|
Assembly 1
Protein–RNA
Heteromer；Protein × 76
PDB declaration: 80-meric
|
Chain 3K
1–151（151 aa）
|
Not recorded
|
84D Dibekacin × 24
MG MAGNESIUM ION × 397
ZN ZINC ION × 4
|
ELECTRON MICROSCOPY
cryo-EM buffer
pH 7.4
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 2.59 Å
|
|
8IFE
Arbekacin-added human 80S ribosome
Deposited 2023-02-17
|
Different oligomeric state
Different ligand/ion
Different experimental conditions
Different structure-quality metrics
|
Assembly 1
Protein–RNA
Heteromer；Protein × 76
PDB declaration: 80-meric
|
Chain 3K
1–151（151 aa）
|
Not recorded
|
84G Arbekacin × 23
MG MAGNESIUM ION × 410
ZN ZINC ION × 6
|
ELECTRON MICROSCOPY
cryo-EM buffer
pH 7.4
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 2.57 Å
|
|
8JDJ
Structure of the Human cytoplasmic Ribosome with human tRNA Asp(Q34) and mRNA(GAU)
Deposited 2023-05-14
|
Different oligomeric state
Different ligand/ion
Different experimental conditions
Different structure-quality metrics
|
Assembly 1
Protein–RNA
Heteromer；Protein × 73
PDB declaration: 80-meric
|
Chain 9
1–151（151 aa）
|
Not recorded
|
MG MAGNESIUM ION × 539
ZN ZINC ION × 6
|
ELECTRON MICROSCOPY
cryo-EM buffer
pH 7.4；The Buffer pH was adjusted to 7.4 using KOH.
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 2.50 Å
|
|
8JDK
Structure of the Human cytoplasmic Ribosome with human tRNA Asp(ManQ34) and mRNA(GAU)
Deposited 2023-05-14
|
Different oligomeric state
Different ligand/ion
Different experimental conditions
Different structure-quality metrics
|
Assembly 1
Protein–RNA
Heteromer；Protein × 73
PDB declaration: 80-meric
|
Chain 9
1–151（151 aa）
|
Not recorded
|
MG MAGNESIUM ION × 539
MAN alpha-D-mannopyranose × 2
ZN ZINC ION × 6
|
ELECTRON MICROSCOPY
cryo-EM buffer
pH 7.4；The Buffer pH was adjusted to 7.4 using KOH.
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 2.26 Å
|
|
8JDL
Structure of the Human cytoplasmic Ribosome with human tRNA Tyr(GalQ34) and mRNA(UAU) (non-rotated state)
Deposited 2023-05-14
|
Different oligomeric state
Different ligand/ion
Different experimental conditions
Different structure-quality metrics
|
Assembly 1
Protein–RNA
Heteromer；Protein × 73
PDB declaration: 79-meric
|
Chain 9
1–151（151 aa）
|
Not recorded
|
MG MAGNESIUM ION × 539
GAL beta-D-galactopyranose × 1
ZN ZINC ION × 6
|
ELECTRON MICROSCOPY
cryo-EM buffer
pH 7.4；The Buffer pH was adjusted to 7.4 using KOH.
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 2.42 Å
|
|
8JDM
Structure of the Human cytoplasmic Ribosome with human tRNA Tyr(GalQ34) and mRNA(UAU) (rotated state)
Deposited 2023-05-14
|
Different oligomeric state
Different ligand/ion
Different experimental conditions
Different structure-quality metrics
|
Assembly 1
Protein–RNA
Heteromer；Protein × 73
PDB declaration: 80-meric
|
Chain 9
1–151（151 aa）
|
Not recorded
|
GAL beta-D-galactopyranose × 2
MG MAGNESIUM ION × 520
ZN ZINC ION × 6
|
ELECTRON MICROSCOPY
cryo-EM buffer
pH 7.4；The Buffer pH was adjusted to 7.4 using KOH.
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 2.67 Å
|
|
8K2C
Cryo-EM structure of the human 80S ribosome with Tigecycline
Deposited 2023-07-12
|
Different oligomeric state
Different ligand/ion
Different experimental conditions
Different structure-quality metrics
|
Assembly 1
Protein–RNA
Heteromer；Protein × 81
PDB declaration: 86-meric
|
Chain SN
1–151（151 aa）
|
Not recorded
|
MG MAGNESIUM ION × 259
T1C TIGECYCLINE × 9
ZN ZINC ION × 8
|
ELECTRON MICROSCOPY
cryo-EM buffer
pH 7.4
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 2.40 Å
|
|
8OZ0
Structure of a human 48S translation initiation complex with eIF4F and eIF4A
Deposited 2023-05-06
|
Different oligomeric state
Different ligand/ion
Different experimental conditions
Different structure-quality metrics
|
Assembly 1
Protein–RNA
Heteromer；Protein × 54
PDB declaration: 57-meric
|
Chain V
1–151（151 aa）
|
Not recorded
|
ZN ZINC ION × 2
MG MAGNESIUM ION × 89
|
ELECTRON MICROSCOPY
cryo-EM buffer
pH 7.4
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 3.50 Å
|
|
8PJ1
Structure of human 48S translation initiation complex in open codon scanning state (48S-1)
Deposited 2023-06-22
|
Different oligomeric state
Different ligand/ion
|
Assembly 1
Protein–RNA
Heteromer；Protein × 51
PDB declaration: 54-meric
|
Chain I
1–151（151 aa）
|
Not recorded
|
MG MAGNESIUM ION × 90
ZN ZINC ION × 3
GTP GUANOSINE-5'-TRIPHOSPHATE × 1
MET METHIONINE × 1
|
ELECTRON MICROSCOPY
cryo-EM buffer
pH 7.5
cryo-EM vitrification conditions
Cryogen ETHANE；Manual blotting & plunge-freezing
|
Resolution 3.40 Å
|
|
8PJ2
Structure of human 48S translation initiation complex in AUG recognition state after eIF5-induced GTP hydrolysis by eIF2 (48S-2)
Deposited 2023-06-22
|
Different oligomeric state
Different ligand/ion
|
Assembly 1
Protein–RNA
Heteromer；Protein × 46
PDB declaration: 49-meric
|
Chain I
1–151（151 aa）
|
Not recorded
|
MG MAGNESIUM ION × 87
ZN ZINC ION × 2
|
ELECTRON MICROSCOPY
cryo-EM buffer
pH 7.5
cryo-EM vitrification conditions
Cryogen ETHANE；Manual blotting & plunge-freezing
|
Resolution 3.40 Å
|
|
8PJ3
Structure of human 48S translation initiation complex upon transfer of initiator tRNA to eIF5B (48S-3)
Deposited 2023-06-22
|
Different oligomeric state
Different ligand/ion
Different structure-quality metrics
|
Assembly 1
Protein–RNA
Heteromer；Protein × 51
PDB declaration: 54-meric
|
Chain I
1–151（151 aa）
|
Not recorded
|
GTP GUANOSINE-5'-TRIPHOSPHATE × 1
NA SODIUM ION × 1
MG MAGNESIUM ION × 89
ZN ZINC ION × 2
|
ELECTRON MICROSCOPY
cryo-EM buffer
pH 7.5
cryo-EM vitrification conditions
Cryogen ETHANE；Manual blotting & plunge-freezing
|
Resolution 3.70 Å
|
|
8PJ4
Structure of human 48S translation initiation complex after eIF5 release (48S-4)
Deposited 2023-06-22
|
Different oligomeric state
Different ligand/ion
Different structure-quality metrics
|
Assembly 1
Protein–RNA
Heteromer；Protein × 50
PDB declaration: 53-meric
|
Chain I
1–151（151 aa）
|
Not recorded
|
GTP GUANOSINE-5'-TRIPHOSPHATE × 1
NA SODIUM ION × 1
MG MAGNESIUM ION × 89
ZN ZINC ION × 2
|
ELECTRON MICROSCOPY
cryo-EM buffer
pH 7.5
cryo-EM vitrification conditions
Cryogen ETHANE；Manual blotting & plunge-freezing
|
Resolution 3.20 Å
|
|
8PJ5
Structure of human 48S translation initiation complex after eIF2 release prior 60S subunit joining (48S-5)
Deposited 2023-06-22
|
Different oligomeric state
Different ligand/ion
Different structure-quality metrics
|
Assembly 1
Protein–RNA
Heteromer；Protein × 48
PDB declaration: 51-meric
|
Chain I
1–151（151 aa）
|
Not recorded
|
MG MAGNESIUM ION × 91
GTP GUANOSINE-5'-TRIPHOSPHATE × 1
ZN ZINC ION × 2
|
ELECTRON MICROSCOPY
cryo-EM buffer
pH 7.5
cryo-EM vitrification conditions
Cryogen ETHANE；Manual blotting & plunge-freezing
|
Resolution 2.90 Å
|
|
8PJ6
Structure of human 48S translation initiation complex with initiator tRNA, eIF1A and eIF3 (off-pathway)
Deposited 2023-06-22
|
Different oligomeric state
Different ligand/ion
Different structure-quality metrics
|
Assembly 1
Protein–RNA
Heteromer；Protein × 47
PDB declaration: 50-meric
|
Chain I
1–151（151 aa）
|
Not recorded
|
MG MAGNESIUM ION × 87
ZN ZINC ION × 2
|
ELECTRON MICROSCOPY
cryo-EM buffer
pH 7.5
cryo-EM vitrification conditions
Cryogen ETHANE；Manual blotting & plunge-freezing
|
Resolution 2.90 Å
|
|
8PPK
Bat-Hp-CoV Nsp1 and eIF1 bound to the human 40S small ribosomal subunit
Deposited 2023-07-07
|
Different oligomeric state
Different ligand/ion
Different experimental conditions
Different structure-quality metrics
|
Assembly 1
Protein–RNA
Heteromer；Protein × 36
PDB declaration: 37-meric
|
Chain N
1–151（151 aa）
|
Not recorded
|
UNX UNKNOWN LIGAND × 117
MG MAGNESIUM ION × 111
ZN ZINC ION × 3
|
ELECTRON MICROSCOPY
cryo-EM buffer
pH 7.4
cryo-EM vitrification conditions
Cryogen ETHANE-PROPANE
|
Resolution 2.98 Å
|
|
8PPL
MERS-CoV Nsp1 bound to the human 43S pre-initiation complex
Deposited 2023-07-07
|
Different oligomeric state
Different ligand/ion
Different experimental conditions
Different structure-quality metrics
|
Assembly 1
Protein–RNA
Heteromer；Protein × 50
PDB declaration: 52-meric
|
Chain AN
1–151（151 aa）
|
Not recorded
|
ZN ZINC ION × 4
GTP GUANOSINE-5'-TRIPHOSPHATE × 1
MG MAGNESIUM ION × 116
MET METHIONINE × 1
UNX UNKNOWN LIGAND × 129
|
ELECTRON MICROSCOPY
cryo-EM buffer
pH 7.4
cryo-EM vitrification conditions
Cryogen ETHANE-PROPANE
|
Resolution 2.65 Å
|
|
8QOI
Structure of the human 80S ribosome at 1.9 A resolution - the molecular role of chemical modifications and ions in RNA
Deposited 2023-09-29
|
Different oligomeric state
Different ligand/ion
Different experimental conditions
Different structure-quality metrics
|
Assembly 1
Protein–RNA
Heteromer；Protein × 75
PDB declaration: 79-meric
|
Chain SN
1–151（151 aa）
|
Not recorded
|
MG MAGNESIUM ION × 292
K POTASSIUM ION × 108
SPD SPERMIDINE × 2
ZN ZINC ION × 8
|
ELECTRON MICROSCOPY
cryo-EM buffer
pH 7.6；Titan Krios sample is prepared with Sodium cacodylate buffer.
CryoARM 300 sample is prepared with Hepes buffer.
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 1.90 Å
|
|
8T4S
MERS-CoV Nsp1 protein bound to the Human 40S Ribosomal subunit
Deposited 2023-06-09
|
Different oligomeric state
Different ligand/ion
Different experimental conditions
Different structure-quality metrics
|
Assembly 1
Protein–RNA
Heteromer；Protein × 35
PDB declaration: 36-meric
|
Chain N
1–151（151 aa）
|
Not recorded
|
MG MAGNESIUM ION × 97
ZN ZINC ION × 3
|
ELECTRON MICROSCOPY
cryo-EM buffer
pH 7.5
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 2.60 Å
|
|
8UKB
In situ HHT and CHX treated human hibernating state without E-tRNA 80S ribosome
Deposited 2023-10-12
|
Different construct
Different oligomeric state
Different ligand/ion
Different experimental conditions
Different structure-quality metrics
|
Assembly 1
Protein–RNA
Heteromer；Protein × 80
PDB declaration: 84-meric
|
Chain SN
2–151（150 aa）
|
Not recorded
|
MG MAGNESIUM ION × 255
HMT (3beta)-O~3~-[(2R)-2,6-dihydroxy-2-(2-methoxy-2-oxoethyl)-6-methylheptanoyl]cephalotaxine × 1
WV3 4-{(2R)-2-[(1R,3S,5S)-3,5-dimethyl-2-oxocyclohexyl]-2-hydroxyethyl}piperidine-2,6-dione × 1
ZN ZINC ION × 6
|
ELECTRON MICROSCOPY
cryo-EM buffer
pH 7.4
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 3.05 Å
|
|
8XP2
Cryo-EM structure of the human 40S ribosome with LARP1
Deposited 2024-01-02
|
Different oligomeric state
Different ligand/ion
Different experimental conditions
Different structure-quality metrics
|
Assembly 1
Protein–RNA
Heteromer；Protein × 35
PDB declaration: 36-meric
|
Chain SN
1–151（151 aa）
|
Not recorded
|
ZN ZINC ION × 4
|
ELECTRON MICROSCOPY
cryo-EM buffer
pH 7.4
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 3.20 Å
|
|
8XP3
Cryo-EM structure of the human 40S ribosome with LARP1 and LRRC47
Deposited 2024-01-02
|
Different oligomeric state
Different ligand/ion
Different experimental conditions
|
Assembly 1
Protein–RNA
Heteromer；Protein × 36
PDB declaration: 37-meric
|
Chain SN
1–151（151 aa）
|
Not recorded
|
ZN ZINC ION × 4
|
ELECTRON MICROSCOPY
cryo-EM buffer
pH 7.4
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 3.40 Å
|
|
8XSX
Cryo-EM structure of the human 80S ribosome with Tigecycline, E-tRNA, SERBP1 and eEF2
Deposited 2024-01-10
|
Different oligomeric state
Different ligand/ion
Different experimental conditions
Different structure-quality metrics
|
Assembly 1
Protein–RNA
Heteromer；Protein × 81
PDB declaration: 86-meric
|
Chain SN
1–151（151 aa）
|
Not recorded
|
MG MAGNESIUM ION × 259
T1C TIGECYCLINE × 7
ZN ZINC ION × 8
ADP ADENOSINE-5'-DIPHOSPHATE × 1
|
ELECTRON MICROSCOPY
cryo-EM buffer
pH 7.4
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 2.40 Å
|
|
8XSY
Cryo-EM structure of the human 80S ribosome with Tigecycline, e-tRNA and CCDC124 (40S head Swivelled)
Deposited 2024-01-10
|
Different oligomeric state
Different ligand/ion
Different experimental conditions
Different structure-quality metrics
|
Assembly 1
Protein–RNA
Heteromer；Protein × 81
PDB declaration: 86-meric
|
Chain SN
1–151（151 aa）
|
Not recorded
|
MG MAGNESIUM ION × 255
T1C TIGECYCLINE × 8
ZN ZINC ION × 8
|
ELECTRON MICROSCOPY
cryo-EM buffer
pH 7.4
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 3.00 Å
|
|
8XSZ
Cryo-EM structure of the human 80S ribosome with Tigecycline, E-tRNA and P-tRNA
Deposited 2024-01-10
|
Different oligomeric state
Different ligand/ion
Different experimental conditions
Different structure-quality metrics
|
Assembly 1
Protein–RNA
Heteromer；Protein × 79
PDB declaration: 86-meric
|
Chain SN
1–151（151 aa）
|
Not recorded
|
MG MAGNESIUM ION × 248
T1C TIGECYCLINE × 5
ZN ZINC ION × 8
|
ELECTRON MICROSCOPY
cryo-EM buffer
pH 7.4
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 3.20 Å
|
|
8XXL
Cryo-EM structure of the human 40S ribosome with PDCD4
Deposited 2024-01-18
|
Different oligomeric state
Different ligand/ion
Different experimental conditions
Different structure-quality metrics
|
Assembly 1
Protein–RNA
Heteromer；Protein × 35
PDB declaration: 36-meric
|
Chain SN
1–151（151 aa）
|
Not recorded
|
MG MAGNESIUM ION × 22
ZN ZINC ION × 3
|
ELECTRON MICROSCOPY
cryo-EM buffer
pH 7.4
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 2.90 Å
|
|
8XXM
Cryo-EM structure of the human 40S ribosome with PDCD4 and eIF3G
Deposited 2024-01-18
|
Different oligomeric state
Different ligand/ion
Different experimental conditions
Different structure-quality metrics
|
Assembly 1
Protein–RNA
Heteromer；Protein × 36
PDB declaration: 37-meric
|
Chain SN
1–151（151 aa）
|
Not recorded
|
MG MAGNESIUM ION × 23
ZN ZINC ION × 3
|
ELECTRON MICROSCOPY
cryo-EM buffer
pH 7.4
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 3.20 Å
|
|
8XXN
Cryo-EM structure of the human 43S ribosome with PDCD4
Deposited 2024-01-18
|
Different oligomeric state
Different ligand/ion
Different experimental conditions
Different structure-quality metrics
|
Assembly 1
Protein–RNA
Heteromer；Protein × 49
PDB declaration: 50-meric
|
Chain SN
1–151（151 aa）
|
Not recorded
|
MG MAGNESIUM ION × 23
ZN ZINC ION × 3
|
ELECTRON MICROSCOPY
cryo-EM buffer
pH 7.4
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 3.60 Å
|
|
8Y0W
dormant ribosome with eIF5A, eEF2 and SERBP1
Deposited 2024-01-23
|
Different oligomeric state
Different ligand/ion
Different experimental conditions
|
Assembly 1
Protein–RNA
Heteromer；Protein × 77
PDB declaration: 81-meric
|
Chain SN
1–151（151 aa）
|
Not recorded
|
MG MAGNESIUM ION × 226
ZN ZINC ION × 5
|
ELECTRON MICROSCOPY
cryo-EM buffer
pH 7.5；50mM HEPES, pH7.5, 100mM KOAc, 5mM Mg(OAc)2, 1mM DTT
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 3.40 Å
|
|
8Y0X
Dormant ribosome with SERBP1
Deposited 2024-01-23
|
Different oligomeric state
Different ligand/ion
Different experimental conditions
Different structure-quality metrics
|
Assembly 1
Protein–RNA
Heteromer；Protein × 75
PDB declaration: 80-meric
|
Chain SN
1–151（151 aa）
|
Not recorded
|
MG MAGNESIUM ION × 255
ZN ZINC ION × 7
|
ELECTRON MICROSCOPY
cryo-EM buffer
pH 7.4；50mM HEPES, pH7.4, 100mM KoAc, 5mM Mg(OAc)2, 1mM DTT
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 3.30 Å
|
|
8YOO
Cryo-EM structure of the human 80S ribosome with 100 um Tigecycline
Deposited 2024-03-13
|
Different oligomeric state
Different ligand/ion
Different experimental conditions
Different structure-quality metrics
|
Assembly 1
Protein–RNA
Heteromer；Protein × 77
PDB declaration: 81-meric
|
Chain SN
1–151（151 aa）
|
Not recorded
|
MG MAGNESIUM ION × 257
T1C TIGECYCLINE × 6
ZN ZINC ION × 8
|
ELECTRON MICROSCOPY
cryo-EM buffer
pH 7.4
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 2.00 Å
|
|
8YOP
Cryo-EM structure of the human 80S ribosome with 4 um Tigecycline
Deposited 2024-03-13
|
Different oligomeric state
Different ligand/ion
Different experimental conditions
Different structure-quality metrics
|
Assembly 1
Protein–RNA
Heteromer；Protein × 78
PDB declaration: 82-meric
|
Chain SN
1–151（151 aa）
|
Not recorded
|
MG MAGNESIUM ION × 255
ZN ZINC ION × 8
|
ELECTRON MICROSCOPY
cryo-EM buffer
pH 7.4
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 2.20 Å
|
|
8ZDB
Cryo-EM structure of the human ubiquitylated 40S ribosome with RIOK3
Deposited 2024-05-01
|
Different oligomeric state
Different ligand/ion
Different experimental conditions
Different structure-quality metrics
|
Assembly 1
Protein–RNA
Heteromer；Protein × 37
PDB declaration: 38-meric
|
Chain N
1–151（151 aa）
|
Not recorded
|
ZN ZINC ION × 2
|
ELECTRON MICROSCOPY
cryo-EM buffer
pH 7.4
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 3.60 Å
|
|
8ZDC
Cryo-EM structure of the human ubiquitylated pre-40S ribosome with RIOK3
Deposited 2024-05-01
|
Different oligomeric state
Different ligand/ion
Different experimental conditions
Different structure-quality metrics
|
Assembly 1
Protein–RNA
Heteromer；Protein × 37
PDB declaration: 38-meric
|
Chain N
1–151（151 aa）
|
Not recorded
|
ZN ZINC ION × 2
|
ELECTRON MICROSCOPY
cryo-EM buffer
pH 7.4
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 3.80 Å
|
|
8ZDD
Cryo-EM structure of the human ubiquitylated pre-40S ribosome with RIOK3 (without NOB1)
Deposited 2024-05-01
|
Different oligomeric state
Different ligand/ion
Different experimental conditions
Different structure-quality metrics
|
Assembly 1
Protein–RNA
Heteromer；Protein × 36
PDB declaration: 37-meric
|
Chain N
1–151（151 aa）
|
Not recorded
|
ZN ZINC ION × 1
|
ELECTRON MICROSCOPY
cryo-EM buffer
pH 7.4
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 3.70 Å
|
|
9B0P
In situ human Hibernating class1 80S ribosome
Deposited 2024-03-12
|
Different construct
Different oligomeric state
Different ligand/ion
Different experimental conditions
Different structure-quality metrics
|
Assembly 1
Protein–RNA
Heteromer；Protein × 80
PDB declaration: 85-meric
|
Chain SN
2–151（150 aa）
|
Not recorded
|
MG MAGNESIUM ION × 255
ZN ZINC ION × 6
|
ELECTRON MICROSCOPY
cryo-EM buffer
pH 7.4
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 2.82 Å
|
|
9B0Q
In situ human top-back di-ribosome structure (Composite map)
Deposited 2024-03-12
|
Different construct
Different mutation/modification
Different oligomeric state
Different ligand/ion
Different experimental conditions
Different structure-quality metrics
|
Assembly 1
Protein–RNA
Heteromer；Protein × 160
PDB declaration: 172-meric
|
Chain SN
2–151（150 aa）
Chain sN
2–151（150 aa）
|
Not recorded
|
ZN ZINC ION × 12
MG MAGNESIUM ION × 510
|
ELECTRON MICROSCOPY
cryo-EM buffer
pH 7.4
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 3.20 Å
|
|
9B0S
In situ human top-top di-ribosome structure (Composite map)
Deposited 2024-03-12
|
Different construct
Different mutation/modification
Different oligomeric state
Different ligand/ion
Different experimental conditions
Different structure-quality metrics
|
Assembly 1
Protein–RNA
Heteromer；Protein × 158
PDB declaration: 171-meric
|
Chain SN
2–151（150 aa）
Chain sN
2–151（150 aa）
|
Not recorded
|
ZN ZINC ION × 12
MG MAGNESIUM ION × 510
|
ELECTRON MICROSCOPY
cryo-EM buffer
pH 7.4
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 3.80 Å
|
|
9BKD
The structure of human Pdcd4 bound to the 40S small ribosomal subunit
Deposited 2024-04-27
|
Different oligomeric state
Different ligand/ion
Different experimental conditions
Different structure-quality metrics
|
Assembly 1
Protein–RNA
Heteromer；Protein × 35
PDB declaration: 36-meric
|
Chain I
1–151（151 aa）
|
Not recorded
|
ZN ZINC ION × 3
K POTASSIUM ION × 19
MG MAGNESIUM ION × 88
SPD SPERMIDINE × 1
|
ELECTRON MICROSCOPY
cryo-EM buffer
pH 7.5
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 2.60 Å
|
|
9BLN
The structure of human Pdcd4 bound to the 40S-eIF4A-eIF3-eIF1 complex
Deposited 2024-04-30
|
Different oligomeric state
Different ligand/ion
Different experimental conditions
Different structure-quality metrics
|
Assembly 1
Protein–RNA
Heteromer；Protein × 49
PDB declaration: 50-meric
|
Chain I
1–151（151 aa）
|
Not recorded
|
MG MAGNESIUM ION × 88
K POTASSIUM ION × 19
SPD SPERMIDINE × 1
ZN ZINC ION × 3
ACY ACETIC ACID × 1
|
ELECTRON MICROSCOPY
cryo-EM buffer
pH 7.4
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 3.90 Å
|
|
9C3H
Structure of the CNOT3-bound human 80S ribosome with tRNA-ARG in the P-site.
Deposited 2024-06-01
|
Different oligomeric state
Different ligand/ion
Different experimental conditions
Different structure-quality metrics
|
Assembly 1
Protein–RNA
Heteromer；Protein × 77
PDB declaration: 83-meric
|
Chain SN
1–151（151 aa）
|
Not recorded
|
MG MAGNESIUM ION × 326
K POTASSIUM ION × 94
B3P 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL × 1
ZN ZINC ION × 8
|
ELECTRON MICROSCOPY
cryo-EM buffer
pH 7.5
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 2.00 Å
|
|
9ED0
Human LARP1 bound to the 40S small ribosomal subunit
Deposited 2024-11-15
|
Different oligomeric state
Different ligand/ion
Different experimental conditions
Different structure-quality metrics
|
Assembly 1
Protein–RNA
Heteromer；Protein × 35
PDB declaration: 36-meric
|
Chain N
1–151（151 aa）
|
Not recorded
|
K POTASSIUM ION × 71
MG MAGNESIUM ION × 92
ZN ZINC ION × 3
|
ELECTRON MICROSCOPY
cryo-EM buffer
pH 7.4
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 2.80 Å
|
|
9FQZ
CRYO-EM STRUCTURE OF HCT15 POLYSOMES BOUND TO EEF2, EBP1, AND SERBP1
Deposited 2024-06-17
|
Different oligomeric state
Different ligand/ion
Different experimental conditions
Different structure-quality metrics
|
Assembly 1
Protein–RNA
Heteromer；Protein × 79
PDB declaration: 84-meric
|
Chain SN
1–151（151 aa）
|
Not recorded
|
GDP GUANOSINE-5'-DIPHOSPHATE × 1
MG MAGNESIUM ION × 271
K POTASSIUM ION × 104
ZN ZINC ION × 8
PUT 1,4-DIAMINOBUTANE × 7
HYG HYGROMYCIN B × 1
SPD SPERMIDINE × 8
3HE 4-{(2R)-2-[(1S,3S,5S)-3,5-dimethyl-2-oxocyclohexyl]-2-hydroxyethyl}piperidine-2,6-dione × 1
ANM ANISOMYCIN × 1
NA SODIUM ION × 1
|
ELECTRON MICROSCOPY
cryo-EM buffer
pH 7.6
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 2.85 Å
|
|
9G8M
human 80S ribosome bound by a SKI2-exosome complex
Deposited 2024-07-23
|
Different oligomeric state
Different ligand/ion
Different experimental conditions
Different structure-quality metrics
|
Assembly 1
Insufficient information
Heteromer；Protein × 87
PDB declaration: 92-meric
|
Chain SN
1–151（151 aa）
|
Not recorded
|
MG MAGNESIUM ION × 232
ZN ZINC ION × 6
|
ELECTRON MICROSCOPY
cryo-EM buffer
pH 7.5
cryo-EM vitrification conditions
Cryogen ETHANE-PROPANE
|
Resolution 3.30 Å
|
|
9G8O
human 40S ribosome bound by a SKI238-exosome complex
Deposited 2024-07-23
|
Different oligomeric state
Different ligand/ion
Different experimental conditions
|
Assembly 1
Protein–RNA
Heteromer；Protein × 49
PDB declaration: 51-meric
|
Chain SN
1–151（151 aa）
|
Not recorded
|
No recorded non-water small molecule
|
ELECTRON MICROSCOPY
cryo-EM buffer
pH 7.4
cryo-EM vitrification conditions
Cryogen ETHANE-PROPANE
|
Resolution 3.40 Å
|
|
9I14
CRYO-EM STRUCTURE OF HCT15 POLYSOMES IN HYBRID-PRE STATE
Deposited 2025-01-15
|
Different oligomeric state
Different ligand/ion
Different experimental conditions
Different structure-quality metrics
|
Assembly 1
Protein–RNA
Heteromer；Protein × 75
PDB declaration: 82-meric
|
Chain SN
1–151（151 aa）
|
Not recorded
|
K POTASSIUM ION × 40
MG MAGNESIUM ION × 267
NA SODIUM ION × 23
SPD SPERMIDINE × 1
PUT 1,4-DIAMINOBUTANE × 1
ZN ZINC ION × 7
HYG HYGROMYCIN B × 1
|
ELECTRON MICROSCOPY
cryo-EM buffer
pH 7.6
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 3.34 Å
|
|
9I2D
NMT1-NAC bound human RNC with 10 amino acid ARF1-linker
Deposited 2025-01-20
|
Different oligomeric state
Different ligand/ion
Different experimental conditions
Different structure-quality metrics
|
Assembly 1
Protein–RNA
Heteromer；Protein × 82
PDB declaration: 88-meric
|
Chain SN
1–151（151 aa）
|
Not recorded
|
MG MAGNESIUM ION × 191
ZN ZINC ION × 8
|
ELECTRON MICROSCOPY
cryo-EM buffer
pH 7.5
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 2.19 Å
|
|
9I2E
NMT1-NAC bound human ribosome (combined translational states)
Deposited 2025-01-20
|
Different oligomeric state
Different ligand/ion
Different experimental conditions
Different structure-quality metrics
|
Assembly 1
Protein–RNA
Heteromer；Protein × 81
PDB declaration: 86-meric
|
Chain SN
1–151（151 aa）
|
Not recorded
|
MG MAGNESIUM ION × 256
ZN ZINC ION × 8
|
ELECTRON MICROSCOPY
cryo-EM buffer
pH 7.5
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 2.95 Å
|
|
9KKF
Structure of the human 40S ribosome complexed with HCV IRES and eIF3
Deposited 2024-11-13
|
Different oligomeric state
Different ligand/ion
Different experimental conditions
Different structure-quality metrics
|
Assembly 1
Protein–RNA
Heteromer；Protein × 43
PDB declaration: 45-meric
|
Chain SN
1–151（151 aa）
|
Not recorded
|
ZN ZINC ION × 2
MG MAGNESIUM ION × 8
|
ELECTRON MICROSCOPY
cryo-EM buffer
pH 7.5
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 3.30 Å
|
|
9KMT
Bat SARSr-CoV RaTG15 Nsp1 bound to the Human 40S Ribosomal subunit-State1
Deposited 2024-11-18
|
Different oligomeric state
Different ligand/ion
Different experimental conditions
Different structure-quality metrics
|
Assembly 1
Protein–RNA
Heteromer；Protein × 35
PDB declaration: 36-meric
|
Chain N
1–151（151 aa）
|
Not recorded
|
No recorded non-water small molecule
|
ELECTRON MICROSCOPY
cryo-EM buffer
pH 8
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 2.81 Å
|
|
9KMU
Bat SARSr-CoV RaTG15 Nsp1 bound to the Human 40S Ribosomal subunit-State2
Deposited 2024-11-18
|
Different oligomeric state
Different ligand/ion
Different experimental conditions
Different structure-quality metrics
|
Assembly 1
Protein–RNA
Heteromer；Protein × 35
PDB declaration: 36-meric
|
Chain N
1–151（151 aa）
|
Not recorded
|
No recorded non-water small molecule
|
ELECTRON MICROSCOPY
cryo-EM buffer
pH 8
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 2.87 Å
|
|
9KMV
SARSr-MpCoV-GX Nsp1 bound to the Human 40S Ribosomal subunit-State1
Deposited 2024-11-18
|
Different oligomeric state
Different ligand/ion
Different experimental conditions
Different structure-quality metrics
|
Assembly 1
Protein–RNA
Heteromer；Protein × 35
PDB declaration: 36-meric
|
Chain N
1–151（151 aa）
|
Not recorded
|
No recorded non-water small molecule
|
ELECTRON MICROSCOPY
cryo-EM buffer
pH 8
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 2.65 Å
|
|
9KMW
SARSr-MpCoV-GX Nsp1 bound to the Human 40S Ribosomal subunit-State2
Deposited 2024-11-18
|
Different oligomeric state
Different ligand/ion
Different experimental conditions
Different structure-quality metrics
|
Assembly 1
Protein–RNA
Heteromer；Protein × 35
PDB declaration: 36-meric
|
Chain N
1–151（151 aa）
|
Not recorded
|
No recorded non-water small molecule
|
ELECTRON MICROSCOPY
cryo-EM buffer
pH 8
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 2.73 Å
|
|
9KMX
Bat MERSr-CoV NeoCoV Nsp1 bound to the Human 40S Ribosomal subunit-State1
Deposited 2024-11-18
|
Different oligomeric state
Different ligand/ion
Different experimental conditions
Different structure-quality metrics
|
Assembly 1
Protein–RNA
Heteromer；Protein × 35
PDB declaration: 36-meric
|
Chain N
1–151（151 aa）
|
Not recorded
|
No recorded non-water small molecule
|
ELECTRON MICROSCOPY
cryo-EM buffer
pH 8
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 2.89 Å
|
|
9KMY
Bat MERSr-CoV NeoCoV Nsp1 bound to the Human 40S Ribosomal subunit-State2
Deposited 2024-11-18
|
Different oligomeric state
Different ligand/ion
Different experimental conditions
Different structure-quality metrics
|
Assembly 1
Protein–RNA
Heteromer；Protein × 35
PDB declaration: 36-meric
|
Chain N
1–151（151 aa）
|
Not recorded
|
No recorded non-water small molecule
|
ELECTRON MICROSCOPY
cryo-EM buffer
pH 8
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 2.70 Å
|
|
9KMZ
Bat MERSr-CoV NL140422 Nsp1 bound to the Human 40S Ribosomal subunit-State1
Deposited 2024-11-18
|
Different oligomeric state
Different ligand/ion
Different experimental conditions
Different structure-quality metrics
|
Assembly 1
Protein–RNA
Heteromer；Protein × 35
PDB declaration: 36-meric
|
Chain N
1–151（151 aa）
|
Not recorded
|
No recorded non-water small molecule
|
ELECTRON MICROSCOPY
cryo-EM buffer
pH 8
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 2.78 Å
|
|
9KN0
Bat MERSr-CoV NL140422 Nsp1 bound to the Human 40S Ribosomal subunit-State2
Deposited 2024-11-18
|
Different oligomeric state
Different ligand/ion
Different experimental conditions
Different structure-quality metrics
|
Assembly 1
Protein–RNA
Heteromer；Protein × 35
PDB declaration: 36-meric
|
Chain N
1–151（151 aa）
|
Not recorded
|
No recorded non-water small molecule
|
ELECTRON MICROSCOPY
cryo-EM buffer
pH 8
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 2.65 Å
|
|
9KN5
Structure of the human 40S ribosome complexed with HCV IRES, eIF1A and eIF3
Deposited 2024-11-18
|
Different oligomeric state
Different ligand/ion
Different experimental conditions
Different structure-quality metrics
|
Assembly 1
Protein–RNA
Heteromer；Protein × 44
PDB declaration: 46-meric
|
Chain SN
1–151（151 aa）
|
Not recorded
|
ZN ZINC ION × 2
MG MAGNESIUM ION × 8
|
ELECTRON MICROSCOPY
cryo-EM buffer
pH 7.5
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 3.20 Å
|
|
9KN6
Structure of the HCV IRES-dependent pre-48S translation initiation complex with eIF1A, eIF5B, and eIF3
Deposited 2024-11-18
|
Different oligomeric state
Different ligand/ion
Different experimental conditions
Different structure-quality metrics
|
Assembly 1
Protein–RNA
Heteromer；Protein × 45
PDB declaration: 48-meric
|
Chain SN
1–151（151 aa）
|
Not recorded
|
MG MAGNESIUM ION × 8
GTP GUANOSINE-5'-TRIPHOSPHATE × 1
ZN ZINC ION × 2
|
ELECTRON MICROSCOPY
cryo-EM buffer
pH 7.5
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 3.30 Å
|
|
9KRP
Structure of the HCV IRES-dependent 48S translation initiation complex with eIF5B and eIF3
Deposited 2024-11-28
|
Different oligomeric state
Different ligand/ion
Different experimental conditions
Different structure-quality metrics
|
Assembly 1
Protein–RNA
Heteromer；Protein × 44
PDB declaration: 47-meric
|
Chain SN
1–151（151 aa）
|
Not recorded
|
ZN ZINC ION × 2
MG MAGNESIUM ION × 9
GTP GUANOSINE-5'-TRIPHOSPHATE × 1
|
ELECTRON MICROSCOPY
cryo-EM buffer
pH 7.5
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 3.20 Å
|
|
9KZU
Cryo-EM structure of the HCV IRES-dependently initiated CMV-stalled 80S ribosome (non-rotated state) in complexed with eIF3
Deposited 2024-12-11
|
Different oligomeric state
Different ligand/ion
Different experimental conditions
Different structure-quality metrics
|
Assembly 1
Protein–RNA
Heteromer；Protein × 85
PDB declaration: 92-meric
|
Chain SN
1–151（151 aa）
|
Not recorded
|
MG MAGNESIUM ION × 81
ZN ZINC ION × 7
|
ELECTRON MICROSCOPY
cryo-EM buffer
pH 7.5
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 3.00 Å
|
|
9KZX
Cryo-EM structure of the HCV IRES-dependently initiated CMV-stalled 80S ribosome (rotated state) in complexed with eIF3
Deposited 2024-12-11
|
Different oligomeric state
Different ligand/ion
Different experimental conditions
Different structure-quality metrics
|
Assembly 1
Protein–RNA
Heteromer；Protein × 85
PDB declaration: 93-meric
|
Chain SN
1–151（151 aa）
|
Not recorded
|
MG MAGNESIUM ION × 66
ZN ZINC ION × 7
|
ELECTRON MICROSCOPY
cryo-EM buffer
pH 7.5
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 3.30 Å
|
|
9M0P
Cryo-EM structure of human 80S ribosome in complex with montanine
Deposited 2025-02-25
|
Different oligomeric state
Different ligand/ion
Different experimental conditions
Different structure-quality metrics
|
Assembly 1
Protein–RNA
Heteromer；Protein × 73
PDB declaration: 78-meric
|
Chain SN
1–151（151 aa）
|
Not recorded
|
MG MAGNESIUM ION × 291
ZN ZINC ION × 6
A1L8F (1S,13S,15S,16S)-16-methoxy-5,7-dioxa-12-azapentacyclo[10.6.1.02,10.04,8.013,18]nonadeca-2,4(8),9,17-tetraen-15-ol × 1
|
ELECTRON MICROSCOPY
cryo-EM buffer
pH 7.4
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 2.78 Å
|
|
9O3V
Human 80S ribosome stalled on MYC nascent chain
Deposited 2025-04-07
|
Different oligomeric state
Different ligand/ion
Different experimental conditions
Different structure-quality metrics
|
Assembly 1
Protein–RNA
Heteromer；Protein × 76
PDB declaration: 82-meric
|
Chain SN
1–151（151 aa）
|
Not recorded
|
MG MAGNESIUM ION × 352
K POTASSIUM ION × 165
SPD SPERMIDINE × 14
PUT 1,4-DIAMINOBUTANE × 7
TRS 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL × 2
ZN ZINC ION × 8
|
ELECTRON MICROSCOPY
cryo-EM buffer
pH 7.5；20mM Tris, 100mM KOAc, 7.5mM MgOAc, 0.25mM Spermidine, 2mM DTT, 0.05% w/v b-OG
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 2.20 Å
|
|
9O3W
Human 80S ribosome bound to IDB-001 stalled on MYC nascent chain
Deposited 2025-04-07
|
Different oligomeric state
Different ligand/ion
Different experimental conditions
Different structure-quality metrics
|
Assembly 1
Protein–RNA
Heteromer；Protein × 76
PDB declaration: 82-meric
|
Chain SN
1–151（151 aa）
|
Not recorded
|
K POTASSIUM ION × 170
PUT 1,4-DIAMINOBUTANE × 7
SPD SPERMIDINE × 14
A1B75 (2R,3S,4S)-4-hydroxy-2-[(4-methoxyphenyl)methyl]pyrrolidin-3-yl {2-[(2S)-pyrrolidin-2-yl]ethyl}carbamate × 1
TRS 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL × 2
MG MAGNESIUM ION × 371
ZN ZINC ION × 8
|
ELECTRON MICROSCOPY
cryo-EM buffer
pH 7.5；20mM Tris, 100mM KOAc, 7.5mM MgOAc, 0.25mM Spermidine, 2mM DTT, 0.05% w/v b-OG, 50uM IDB-001
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 1.90 Å
|
|
9O3Y
Human 80S ribosome bound to IDB-002 stalled on FPAK-containing nascent chain
Deposited 2025-04-07
|
Different oligomeric state
Different ligand/ion
Different experimental conditions
Different structure-quality metrics
|
Assembly 1
Protein–RNA
Heteromer；Protein × 76
PDB declaration: 82-meric
|
Chain SN
1–151（151 aa）
|
Not recorded
|
K POTASSIUM ION × 168
SPD SPERMIDINE × 14
PUT 1,4-DIAMINOBUTANE × 7
TRS 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL × 2
MG MAGNESIUM ION × 332
A1B76 (2R,3S,4S)-4-hydroxy-2-[(4-methoxyphenyl)methyl]pyrrolidin-3-yl [(3-fluorophenyl)methyl]carbamate × 1
ZN ZINC ION × 8
|
ELECTRON MICROSCOPY
cryo-EM buffer
pH 7.5；20mM Tris, 100mM KOAc, 7.5mM MgOAc, 0.25mM Spermidine, 2mM DTT, 0.05% w/v b-OG, 50uM IDB-001
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 2.20 Å
|
|
9P6Z
In situ human P-Z state 80S ribosome
Deposited 2025-06-20
|
Different construct
Different oligomeric state
Different ligand/ion
Different experimental conditions
Different structure-quality metrics
|
Assembly 1
Protein–RNA
Heteromer；Protein × 78
PDB declaration: 84-meric
|
Chain SN
2–151（150 aa）
|
Not recorded
|
MG MAGNESIUM ION × 219
SPM SPERMINE × 7
SPD SPERMIDINE × 10
ZN ZINC ION × 6
|
ELECTRON MICROSCOPY
cryo-EM buffer
pH 7.4
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 2.97 Å
|
|
9P72
In situ human P-E state 80S ribosome
Deposited 2025-06-20
|
Different construct
Different oligomeric state
Different ligand/ion
Different experimental conditions
Different structure-quality metrics
|
Assembly 1
Protein–RNA
Heteromer；Protein × 78
PDB declaration: 84-meric
|
Chain SN
2–151（150 aa）
|
Not recorded
|
MG MAGNESIUM ION × 219
SPM SPERMINE × 7
SPD SPERMIDINE × 10
ZN ZINC ION × 6
|
ELECTRON MICROSCOPY
cryo-EM buffer
pH 7.4
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 2.80 Å
|
|
9P73
In situ human eEF2-A/P-P/E state 80S ribosome
Deposited 2025-06-20
|
Different construct
Different oligomeric state
Different ligand/ion
Different experimental conditions
Different structure-quality metrics
|
Assembly 1
Protein–RNA
Heteromer；Protein × 79
PDB declaration: 85-meric
|
Chain SN
2–151（150 aa）
|
Not recorded
|
MG MAGNESIUM ION × 218
ZN ZINC ION × 6
SPM SPERMINE × 7
SPD SPERMIDINE × 10
|
ELECTRON MICROSCOPY
cryo-EM buffer
pH 7.4
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 2.66 Å
|
|
9P76
In situ human eEF1A-A/T-P state 80S ribosome
Deposited 2025-06-20
|
Different construct
Different oligomeric state
Different ligand/ion
Different experimental conditions
Different structure-quality metrics
|
Assembly 1
Protein–RNA
Heteromer；Protein × 79
PDB declaration: 85-meric
|
Chain SN
2–151（150 aa）
|
Not recorded
|
MG MAGNESIUM ION × 219
SPM SPERMINE × 7
SPD SPERMIDINE × 10
ZN ZINC ION × 6
|
ELECTRON MICROSCOPY
cryo-EM buffer
pH 7.4
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 2.83 Å
|
|
9P78
In situ human Hibernating rotate 3 with E-site tRNA state 80S ribosome
Deposited 2025-06-20
|
Different construct
Different oligomeric state
Different ligand/ion
Different experimental conditions
Different structure-quality metrics
|
Assembly 1
Protein–RNA
Heteromer；Protein × 81
PDB declaration: 86-meric
|
Chain SN
2–151（150 aa）
|
Not recorded
|
MG MAGNESIUM ION × 218
SPM SPERMINE × 7
SPD SPERMIDINE × 10
ZN ZINC ION × 6
|
ELECTRON MICROSCOPY
cryo-EM buffer
pH 7.4
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 2.90 Å
|
|
9P79
In situ human Hibernating rotate3 with Z site tRNA state 80S ribosome
Deposited 2025-06-20
|
Different construct
Different oligomeric state
Different ligand/ion
Different experimental conditions
Different structure-quality metrics
|
Assembly 1
Protein–RNA
Heteromer；Protein × 81
PDB declaration: 86-meric
|
Chain SN
2–151（150 aa）
|
Not recorded
|
MG MAGNESIUM ION × 218
SPM SPERMINE × 7
SPD SPERMIDINE × 10
ZN ZINC ION × 6
|
ELECTRON MICROSCOPY
cryo-EM buffer
pH 7.4
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 3.10 Å
|
|
9P7A
In situ human hibernating class2 80S ribosome
Deposited 2025-06-20
|
Different construct
Different oligomeric state
Different ligand/ion
Different experimental conditions
Different structure-quality metrics
|
Assembly 1
Protein–RNA
Heteromer；Protein × 81
PDB declaration: 86-meric
|
Chain SN
2–151（150 aa）
|
Not recorded
|
MG MAGNESIUM ION × 218
SPM SPERMINE × 7
SPD SPERMIDINE × 10
ZN ZINC ION × 6
|
ELECTRON MICROSCOPY
cryo-EM buffer
pH 7.4
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 2.81 Å
|
|
9P7C
In situ human Hibernating class3 80S ribosome
Deposited 2025-06-20
|
Different construct
Different oligomeric state
Different ligand/ion
Different experimental conditions
Different structure-quality metrics
|
Assembly 1
Protein–RNA
Heteromer；Protein × 81
PDB declaration: 86-meric
|
Chain SN
2–151（150 aa）
|
Not recorded
|
MG MAGNESIUM ION × 218
SPM SPERMINE × 7
SPD SPERMIDINE × 10
ZN ZINC ION × 6
|
ELECTRON MICROSCOPY
cryo-EM buffer
pH 7.4
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 2.78 Å
|
|
9P7D
In situ human Hibernating class4 80S ribosome
Deposited 2025-06-20
|
Different construct
Different oligomeric state
Different ligand/ion
Different experimental conditions
Different structure-quality metrics
|
Assembly 1
Protein–RNA
Heteromer；Protein × 81
PDB declaration: 86-meric
|
Chain SN
2–151（150 aa）
|
Not recorded
|
MG MAGNESIUM ION × 218
SPM SPERMINE × 7
SPD SPERMIDINE × 10
ZN ZINC ION × 6
|
ELECTRON MICROSCOPY
cryo-EM buffer
pH 7.4
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 2.57 Å
|
|
9P7E
In situ human Hibernating class5 80S ribosome
Deposited 2025-06-20
|
Different construct
Different oligomeric state
Different ligand/ion
Different experimental conditions
Different structure-quality metrics
|
Assembly 1
Protein–RNA
Heteromer；Protein × 81
PDB declaration: 86-meric
|
Chain SN
2–151（150 aa）
|
Not recorded
|
MG MAGNESIUM ION × 218
SPM SPERMINE × 7
SPD SPERMIDINE × 10
ZN ZINC ION × 6
|
ELECTRON MICROSCOPY
cryo-EM buffer
pH 7.4
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 2.59 Å
|
|
9P7F
In situ HHT and CHX treated A-P state 80S ribosome
Deposited 2025-06-20
|
Different construct
Different oligomeric state
Different ligand/ion
Different experimental conditions
Different structure-quality metrics
|
Assembly 1
Protein–RNA
Heteromer；Protein × 78
PDB declaration: 84-meric
|
Chain SN
2–151（150 aa）
|
Not recorded
|
ZN ZINC ION × 6
MG MAGNESIUM ION × 219
SPM SPERMINE × 7
SPD SPERMIDINE × 10
3HE 4-{(2R)-2-[(1S,3S,5S)-3,5-dimethyl-2-oxocyclohexyl]-2-hydroxyethyl}piperidine-2,6-dione × 1
HMT (3beta)-O~3~-[(2R)-2,6-dihydroxy-2-(2-methoxy-2-oxoethyl)-6-methylheptanoyl]cephalotaxine × 1
|
ELECTRON MICROSCOPY
cryo-EM buffer
pH 7.4
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 3.56 Å
|
|
9P7G
In situ HHT and CHX treated A-P-Z state 80S ribosome
Deposited 2025-06-20
|
Different construct
Different oligomeric state
Different ligand/ion
Different experimental conditions
Different structure-quality metrics
|
Assembly 1
Protein–RNA
Heteromer；Protein × 78
PDB declaration: 85-meric
|
Chain SN
2–151（150 aa）
|
Not recorded
|
MG MAGNESIUM ION × 219
ZN ZINC ION × 6
SPM SPERMINE × 7
SPD SPERMIDINE × 10
3HE 4-{(2R)-2-[(1S,3S,5S)-3,5-dimethyl-2-oxocyclohexyl]-2-hydroxyethyl}piperidine-2,6-dione × 1
HMT (3beta)-O~3~-[(2R)-2,6-dihydroxy-2-(2-methoxy-2-oxoethyl)-6-methylheptanoyl]cephalotaxine × 1
|
ELECTRON MICROSCOPY
cryo-EM buffer
pH 7.4
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 3.54 Å
|
|
9P7H
In situ HHT and CHX treated human eEF1A-A/T-P state 80S ribosome
Deposited 2025-06-20
|
Different construct
Different oligomeric state
Different ligand/ion
Different experimental conditions
Different structure-quality metrics
|
Assembly 1
Protein–RNA
Heteromer；Protein × 79
PDB declaration: 85-meric
|
Chain SN
2–151（150 aa）
|
Not recorded
|
MG MAGNESIUM ION × 219
SPM SPERMINE × 7
SPD SPERMIDINE × 10
HMT (3beta)-O~3~-[(2R)-2,6-dihydroxy-2-(2-methoxy-2-oxoethyl)-6-methylheptanoyl]cephalotaxine × 1
3HE 4-{(2R)-2-[(1S,3S,5S)-3,5-dimethyl-2-oxocyclohexyl]-2-hydroxyethyl}piperidine-2,6-dione × 1
ZN ZINC ION × 6
|
ELECTRON MICROSCOPY
cryo-EM buffer
pH 7.4
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 3.68 Å
|
|
9P7I
In situ HHT and CHX treated human eEF1A-A/T-P-Z state 80S ribosome
Deposited 2025-06-20
|
Different construct
Different oligomeric state
Different ligand/ion
Different experimental conditions
Different structure-quality metrics
|
Assembly 1
Protein–RNA
Heteromer；Protein × 79
PDB declaration: 86-meric
|
Chain SN
2–151（150 aa）
|
Not recorded
|
MG MAGNESIUM ION × 219
SPM SPERMINE × 7
SPD SPERMIDINE × 10
3HE 4-{(2R)-2-[(1S,3S,5S)-3,5-dimethyl-2-oxocyclohexyl]-2-hydroxyethyl}piperidine-2,6-dione × 1
HMT (3beta)-O~3~-[(2R)-2,6-dihydroxy-2-(2-methoxy-2-oxoethyl)-6-methylheptanoyl]cephalotaxine × 1
ZN ZINC ION × 6
|
ELECTRON MICROSCOPY
cryo-EM buffer
pH 7.4
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 3.69 Å
|
|
9P7J
In situ HHT and CHX treated human P state 80S ribosome
Deposited 2025-06-20
|
Different construct
Different oligomeric state
Different ligand/ion
Different experimental conditions
Different structure-quality metrics
|
Assembly 1
Protein–RNA
Heteromer；Protein × 78
PDB declaration: 83-meric
|
Chain SN
2–151（150 aa）
|
Not recorded
|
MG MAGNESIUM ION × 219
SPM SPERMINE × 7
SPD SPERMIDINE × 10
HMT (3beta)-O~3~-[(2R)-2,6-dihydroxy-2-(2-methoxy-2-oxoethyl)-6-methylheptanoyl]cephalotaxine × 1
3HE 4-{(2R)-2-[(1S,3S,5S)-3,5-dimethyl-2-oxocyclohexyl]-2-hydroxyethyl}piperidine-2,6-dione × 1
ZN ZINC ION × 6
|
ELECTRON MICROSCOPY
cryo-EM buffer
pH 7.4
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 3.91 Å
|
|
9P7K
In situ human post eEF1A-A/T-P-E state 80S ribosome
Deposited 2025-06-20
|
Different construct
Different oligomeric state
Different ligand/ion
Different experimental conditions
Different structure-quality metrics
|
Assembly 1
Protein–RNA
Heteromer；Protein × 79
PDB declaration: 86-meric
|
Chain SN
2–151（150 aa）
|
Not recorded
|
MG MAGNESIUM ION × 219
SPM SPERMINE × 7
SPD SPERMIDINE × 10
ZN ZINC ION × 6
|
ELECTRON MICROSCOPY
cryo-EM buffer
pH 7.4
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 2.80 Å
|
|
9P7L
In situ human Post-eEF1A-AT-P state 80S ribosome
Deposited 2025-06-20
|
Different construct
Different oligomeric state
Different ligand/ion
Different experimental conditions
Different structure-quality metrics
|
Assembly 1
Protein–RNA
Heteromer；Protein × 79
PDB declaration: 85-meric
|
Chain SN
2–151（150 aa）
|
Not recorded
|
MG MAGNESIUM ION × 219
SPM SPERMINE × 7
SPD SPERMIDINE × 10
ZN ZINC ION × 6
|
ELECTRON MICROSCOPY
cryo-EM buffer
pH 7.4
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 2.92 Å
|
|
9P7N
In situ human Post-eEF1A-A/T-P-Z state 80S ribosome
Deposited 2025-06-20
|
Different construct
Different oligomeric state
Different ligand/ion
Different experimental conditions
Different structure-quality metrics
|
Assembly 1
Protein–RNA
Heteromer；Protein × 79
PDB declaration: 86-meric
|
Chain SN
2–151（150 aa）
|
Not recorded
|
MG MAGNESIUM ION × 219
SPM SPERMINE × 7
SPD SPERMIDINE × 10
ZN ZINC ION × 6
|
ELECTRON MICROSCOPY
cryo-EM buffer
pH 7.4
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 2.83 Å
|
|
9P7O
In situ human AT-P-Z state ribosome
Deposited 2025-06-20
|
Different construct
Different oligomeric state
Different ligand/ion
Different experimental conditions
Different structure-quality metrics
|
Assembly 1
Protein–RNA
Heteromer；Protein × 79
PDB declaration: 86-meric
|
Chain SN
2–151（150 aa）
|
Not recorded
|
MG MAGNESIUM ION × 219
SPM SPERMINE × 7
SPD SPERMIDINE × 10
ZN ZINC ION × 6
|
ELECTRON MICROSCOPY
cryo-EM buffer
pH 7.4
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 2.65 Å
|
|
9P7W
In situ human A-P state 80S ribosome
Deposited 2025-06-22
|
Different construct
Different oligomeric state
Different ligand/ion
Different experimental conditions
Different structure-quality metrics
|
Assembly 1
Protein–RNA
Heteromer；Protein × 78
PDB declaration: 84-meric
|
Chain SN
2–151（150 aa）
|
Not recorded
|
MG MAGNESIUM ION × 219
ZN ZINC ION × 6
SPM SPERMINE × 7
SPD SPERMIDINE × 10
|
ELECTRON MICROSCOPY
cryo-EM buffer
pH 7.4
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 2.93 Å
|
|
9P7X
In situ human A-P-Z state 80S ribosome
Deposited 2025-06-22
|
Different construct
Different oligomeric state
Different ligand/ion
Different experimental conditions
Different structure-quality metrics
|
Assembly 1
Protein–RNA
Heteromer；Protein × 78
PDB declaration: 85-meric
|
Chain SN
2–151（150 aa）
|
Not recorded
|
ZN ZINC ION × 6
MG MAGNESIUM ION × 219
SPM SPERMINE × 7
SPD SPERMIDINE × 10
|
ELECTRON MICROSCOPY
cryo-EM buffer
pH 7.4
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 2.83 Å
|
|
9P7Y
In situ human A-P-E state 80S ribosome
Deposited 2025-06-22
|
Different construct
Different oligomeric state
Different ligand/ion
Different experimental conditions
Different structure-quality metrics
|
Assembly 1
Protein–RNA
Heteromer；Protein × 78
PDB declaration: 85-meric
|
Chain SN
2–151（150 aa）
|
Not recorded
|
MG MAGNESIUM ION × 219
ZN ZINC ION × 6
SPM SPERMINE × 7
SPD SPERMIDINE × 10
|
ELECTRON MICROSCOPY
cryo-EM buffer
pH 7.4
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 2.75 Å
|
|
9P8B
In situ human eEF1A-A/T-P-E state 80S ribosome
Deposited 2025-06-22
|
Different construct
Different oligomeric state
Different ligand/ion
Different experimental conditions
Different structure-quality metrics
|
Assembly 1
Protein–RNA
Heteromer；Protein × 79
PDB declaration: 86-meric
|
Chain SN
2–151（150 aa）
|
Not recorded
|
MG MAGNESIUM ION × 219
SPM SPERMINE × 7
SPD SPERMIDINE × 10
ZN ZINC ION × 6
|
ELECTRON MICROSCOPY
cryo-EM buffer
pH 7.4
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 2.48 Å
|
|
9P8C
In situ human Hibernating class1 (rotate3) without E tRNA state 80S ribosome
Deposited 2025-06-22
|
Different construct
Different oligomeric state
Different ligand/ion
Different experimental conditions
Different structure-quality metrics
|
Assembly 1
Protein–RNA
Heteromer；Protein × 81
PDB declaration: 85-meric
|
Chain SN
2–151（150 aa）
|
Not recorded
|
MG MAGNESIUM ION × 218
SPM SPERMINE × 7
SPD SPERMIDINE × 10
ZN ZINC ION × 6
|
ELECTRON MICROSCOPY
cryo-EM buffer
pH 7.4
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 3.11 Å
|
|
9P8H
In situ human A/P-P/E state 80S ribosome
Deposited 2025-06-23
|
Different construct
Different oligomeric state
Different ligand/ion
Different experimental conditions
Different structure-quality metrics
|
Assembly 1
Protein–RNA
Heteromer；Protein × 78
PDB declaration: 84-meric
|
Chain SN
2–151（150 aa）
|
Not recorded
|
MG MAGNESIUM ION × 218
ZN ZINC ION × 6
SPM SPERMINE × 7
SPD SPERMIDINE × 10
|
ELECTRON MICROSCOPY
cryo-EM buffer
pH 7.4
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 2.98 Å
|
|
9P8I
In situ HHT and CHX treated human P-Z state 80S ribosome
Deposited 2025-06-23
|
Different construct
Different oligomeric state
Different ligand/ion
Different experimental conditions
Different structure-quality metrics
|
Assembly 1
Protein–RNA
Heteromer；Protein × 78
PDB declaration: 84-meric
|
Chain SN
2–151（150 aa）
|
Not recorded
|
MG MAGNESIUM ION × 219
SPM SPERMINE × 7
SPD SPERMIDINE × 10
3HE 4-{(2R)-2-[(1S,3S,5S)-3,5-dimethyl-2-oxocyclohexyl]-2-hydroxyethyl}piperidine-2,6-dione × 1
HMT (3beta)-O~3~-[(2R)-2,6-dihydroxy-2-(2-methoxy-2-oxoethyl)-6-methylheptanoyl]cephalotaxine × 1
ZN ZINC ION × 6
|
ELECTRON MICROSCOPY
cryo-EM buffer
pH 7.4
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 3.89 Å
|
|
9P9H
In situ human unrotated hibernating with CCDC124 state 80S ribosome
Deposited 2025-06-24
|
Different construct
Different oligomeric state
Different ligand/ion
Different experimental conditions
Different structure-quality metrics
|
Assembly 1
Protein–RNA
Heteromer；Protein × 80
PDB declaration: 85-meric
|
Chain SN
2–151（150 aa）
|
Not recorded
|
MG MAGNESIUM ION × 219
SPM SPERMINE × 7
SPD SPERMIDINE × 10
ZN ZINC ION × 6
|
ELECTRON MICROSCOPY
cryo-EM buffer
pH 7.4
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 2.84 Å
|
|
9P9I
In situ human unrotated hibernating without CCDC124 state 80S ribosome
Deposited 2025-06-24
|
Different construct
Different oligomeric state
Different ligand/ion
Different experimental conditions
Different structure-quality metrics
|
Assembly 1
Protein–RNA
Heteromer；Protein × 79
PDB declaration: 84-meric
|
Chain SN
2–151（150 aa）
|
Not recorded
|
MG MAGNESIUM ION × 219
SPM SPERMINE × 7
SPD SPERMIDINE × 10
ZN ZINC ION × 6
|
ELECTRON MICROSCOPY
cryo-EM buffer
pH 7.4
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 2.77 Å
|
|
9PA7
In situ human 80S consensus ribosome with EBP1
Deposited 2025-06-25
|
Different construct
Different oligomeric state
Different ligand/ion
Different experimental conditions
Different structure-quality metrics
|
Assembly 1
Protein–RNA
Heteromer；Protein × 81
PDB declaration: 87-meric
|
Chain SN
2–151（150 aa）
|
Not recorded
|
MG MAGNESIUM ION × 225
SPM SPERMINE × 8
SPD SPERMIDINE × 12
K POTASSIUM ION × 75
ZN ZINC ION × 7
PUT 1,4-DIAMINOBUTANE × 1
|
ELECTRON MICROSCOPY
cryo-EM buffer
pH 7.4
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 2.67 Å
|
|
9PBE
In situ human 80S ribosome (composite map)
Deposited 2025-06-26
|
Different construct
Different oligomeric state
Different ligand/ion
Different experimental conditions
Different structure-quality metrics
|
Assembly 1
Protein–RNA
Heteromer；Protein × 79
PDB declaration: 84-meric
|
Chain SN
2–151（150 aa）
|
Not recorded
|
MG MAGNESIUM ION × 225
SPM SPERMINE × 8
SPD SPERMIDINE × 12
K POTASSIUM ION × 75
ZN ZINC ION × 7
PUT 1,4-DIAMINOBUTANE × 1
|
ELECTRON MICROSCOPY
cryo-EM buffer
pH 7.4
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 2.19 Å
|
|
9PKG
In situ human P state 80S ribosome
Deposited 2025-07-14
|
Different construct
Different oligomeric state
Different ligand/ion
Different experimental conditions
Different structure-quality metrics
|
Assembly 1
Protein–RNA
Heteromer；Protein × 78
PDB declaration: 83-meric
|
Chain SN
2–151（150 aa）
|
Not recorded
|
MG MAGNESIUM ION × 219
SPM SPERMINE × 7
SPD SPERMIDINE × 10
ZN ZINC ION × 6
|
ELECTRON MICROSCOPY
cryo-EM buffer
pH 7.4
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 3.26 Å
|
|
9QLO
NMT1-NAC bound human RNC with full length ARF1 - State 1
Deposited 2025-03-21
|
Different oligomeric state
Different ligand/ion
Different experimental conditions
Different structure-quality metrics
|
Assembly 1
Protein–RNA
Heteromer；Protein × 82
PDB declaration: 88-meric
|
Chain SN
1–151（151 aa）
|
Not recorded
|
MG MAGNESIUM ION × 191
G3D GUANOSINE-3'-MONOPHOSPHATE-5'-DIPHOSPHATE × 1
ZN ZINC ION × 8
|
ELECTRON MICROSCOPY
cryo-EM buffer
pH 7.5
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 2.47 Å
|
|
9QLP
NMT1-NAC bound human RNC with full length ARF1 - State 2
Deposited 2025-03-21
|
Different oligomeric state
Different ligand/ion
Different experimental conditions
Different structure-quality metrics
|
Assembly 1
Protein–RNA
Heteromer；Protein × 82
PDB declaration: 88-meric
|
Chain SN
1–151（151 aa）
|
Not recorded
|
MG MAGNESIUM ION × 191
G3D GUANOSINE-3'-MONOPHOSPHATE-5'-DIPHOSPHATE × 1
ZN ZINC ION × 8
|
ELECTRON MICROSCOPY
cryo-EM buffer
pH 7.5
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 2.75 Å
|
|
9QLQ
NMT1-NAC bound human RNC with full length ARF1 - alternative State
Deposited 2025-03-21
|
Different oligomeric state
Different ligand/ion
Different experimental conditions
Different structure-quality metrics
|
Assembly 1
Protein–RNA
Heteromer；Protein × 82
PDB declaration: 88-meric
|
Chain SN
1–151（151 aa）
|
Not recorded
|
MG MAGNESIUM ION × 191
ZN ZINC ION × 8
|
ELECTRON MICROSCOPY
cryo-EM buffer
pH 7.5
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 2.57 Å
|
|
9RPV
Structure of the ZAK-bound human disome
Deposited 2025-06-25
|
Different construct
Different mutation/modification
Different oligomeric state
Different ligand/ion
Different experimental conditions
Different structure-quality metrics
|
Assembly 1
Protein–RNA
Heteromer；Protein × 154
PDB declaration: 168-meric
|
Chain RN
1–151（151 aa）
Chain SN
1–151（151 aa）
|
Not recorded
|
MG MAGNESIUM ION × 830
ZN ZINC ION × 7
ANM ANISOMYCIN × 1
|
ELECTRON MICROSCOPY
cryo-EM buffer
pH 7.5
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 2.35 Å
|
|
9RU7
WT-HEK 80S ribosome bound to Kozak mRNA (WT-Kozak)
Deposited 2025-07-03
|
Different oligomeric state
Different ligand/ion
Different experimental conditions
Different structure-quality metrics
|
Assembly 1
Protein–RNA
Heteromer；Protein × 75
PDB declaration: 82-meric
|
Chain SN
1–151（151 aa）
|
Not recorded
|
K POTASSIUM ION × 17
MG MAGNESIUM ION × 74
C CYTIDINE-5'-MONOPHOSPHATE × 2
NA SODIUM ION × 7
ZN ZINC ION × 5
HYG HYGROMYCIN B × 1
|
ELECTRON MICROSCOPY
cryo-EM buffer
pH 7.5
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 3.00 Å
|
|
9RU8
WT-HEK 80S ribosome bound to TISU mRNA (WT-TISU)
Deposited 2025-07-03
|
Different oligomeric state
Different ligand/ion
Different experimental conditions
Different structure-quality metrics
|
Assembly 1
Protein–RNA
Heteromer；Protein × 73
PDB declaration: 80-meric
|
Chain SN
1–151（151 aa）
|
Not recorded
|
No recorded non-water small molecule
|
ELECTRON MICROSCOPY
mmCIF provides none of the parsed conditions
|
Resolution 3.00 Å
|
|
9RU9
RPS26dC HEK mutant 80S ribosome bound to Kozak mRNA (RPS26dC-Kozak)
Deposited 2025-07-03
|
Different oligomeric state
Different ligand/ion
Different experimental conditions
Different structure-quality metrics
|
Assembly 1
Protein–RNA
Heteromer；Protein × 75
PDB declaration: 82-meric
|
Chain SN
1–151（151 aa）
|
Not recorded
|
No recorded non-water small molecule
|
ELECTRON MICROSCOPY
mmCIF provides none of the parsed conditions
|
Resolution 2.97 Å
|
|
9RUA
RPS26dC HEK mutant 80S ribosome bound to TISU mRNA (RPS26dC-TISU)
Deposited 2025-07-03
|
Different oligomeric state
Different ligand/ion
Different experimental conditions
Different structure-quality metrics
|
Assembly 1
Protein–RNA
Heteromer；Protein × 73
PDB declaration: 80-meric
|
Chain SN
1–151（151 aa）
|
Not recorded
|
No recorded non-water small molecule
|
ELECTRON MICROSCOPY
mmCIF provides none of the parsed conditions
|
Resolution 2.90 Å
|
|
9RUC
WT-HEK 80S ribosome bound to H2B mRNA (WT-H2B)
Deposited 2025-07-03
|
Different oligomeric state
Different ligand/ion
Different experimental conditions
Different structure-quality metrics
|
Assembly 1
Protein–RNA
Heteromer；Protein × 73
PDB declaration: 80-meric
|
Chain SN
1–151（151 aa）
|
Not recorded
|
MG MAGNESIUM ION × 223
K POTASSIUM ION × 51
NA SODIUM ION × 8
ZN ZINC ION × 6
HYG HYGROMYCIN B × 1
SPD SPERMIDINE × 3
|
ELECTRON MICROSCOPY
cryo-EM buffer
pH 7.5
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 2.50 Å
|
|
9S3B
NMT1-NAC bound human RNC with 58 amino acid ARF1-linker - State 1
Deposited 2025-07-24
|
Different oligomeric state
Different ligand/ion
Different experimental conditions
Different structure-quality metrics
|
Assembly 1
Protein–RNA
Heteromer；Protein × 82
PDB declaration: 88-meric
|
Chain SN
1–151（151 aa）
|
Not recorded
|
MG MAGNESIUM ION × 191
ZN ZINC ION × 8
|
ELECTRON MICROSCOPY
cryo-EM buffer
pH 7.5
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 2.38 Å
|
|
9S3C
NMT1-NAC bound human RNC with 58 amino acid ARF1-linker - State 2
Deposited 2025-07-24
|
Different oligomeric state
Different ligand/ion
Different experimental conditions
Different structure-quality metrics
|
Assembly 1
Protein–RNA
Heteromer；Protein × 82
PDB declaration: 88-meric
|
Chain SN
1–151（151 aa）
|
Not recorded
|
MG MAGNESIUM ION × 191
ZN ZINC ION × 8
|
ELECTRON MICROSCOPY
cryo-EM buffer
pH 7.5
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 2.42 Å
|
|
9S3D
NAC bound human RNC with 58 amino acid ARF1-linker
Deposited 2025-07-24
|
Different oligomeric state
Different ligand/ion
Different experimental conditions
Different structure-quality metrics
|
Assembly 1
Protein–RNA
Heteromer；Protein × 81
PDB declaration: 87-meric
|
Chain SN
1–151（151 aa）
|
Not recorded
|
MG MAGNESIUM ION × 191
ZN ZINC ION × 8
|
ELECTRON MICROSCOPY
cryo-EM buffer
pH 7.5
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 2.32 Å
|
|
9SPF
CRYO-EM STRUCTURE OF HUMAN 80S RIBOSOME WITH A/P/E-SITE TRNA AND MRNA CONTAINING N1-METHYLPSEUDOURIDINE
Deposited 2025-09-17
|
Different oligomeric state
Different ligand/ion
Different experimental conditions
Different structure-quality metrics
|
Assembly 1
Protein–RNA
Heteromer；Protein × 75
PDB declaration: 83-meric
|
Chain SN
1–151（151 aa）
|
Not recorded
|
K POTASSIUM ION × 151
MG MAGNESIUM ION × 225
NA SODIUM ION × 35
SPD SPERMIDINE × 19
PUT 1,4-DIAMINOBUTANE × 9
ZN ZINC ION × 7
HYG HYGROMYCIN B × 1
|
ELECTRON MICROSCOPY
cryo-EM buffer
pH 7.6
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 2.40 Å
|
|
9SPI
CRYO-EM STRUCTURE OF HUMAN 80S RIBOSOME WITH A/P/E-SITE TRNA AND MRNA CONTAINING URIDINE
Deposited 2025-09-17
|
Different oligomeric state
Different ligand/ion
Different experimental conditions
Different structure-quality metrics
|
Assembly 1
Protein–RNA
Heteromer；Protein × 75
PDB declaration: 83-meric
|
Chain SN
1–151（151 aa）
|
Not recorded
|
PUT 1,4-DIAMINOBUTANE × 8
SPD SPERMIDINE × 18
MG MAGNESIUM ION × 195
K POTASSIUM ION × 75
ZN ZINC ION × 7
HYG HYGROMYCIN B × 1
|
ELECTRON MICROSCOPY
cryo-EM buffer
pH 7.6
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 2.40 Å
|
|
9SYR
Human quaternary complex of a translating 80S ribosome, NAC, MetAP1 and NatD
Deposited 2025-10-13
|
Different oligomeric state
Different ligand/ion
Different experimental conditions
Different structure-quality metrics
|
Assembly 1
Insufficient information
Heteromer；Protein × 80
PDB declaration: 86-meric
|
Chain SF
1–151（151 aa）
|
Not recorded
|
ZN ZINC ION × 10
COA COENZYME A × 1
GTP GUANOSINE-5'-TRIPHOSPHATE × 1
|
ELECTRON MICROSCOPY
cryo-EM buffer
pH 7.4
cryo-EM vitrification conditions
Cryogen ETHANE-PROPANE
|
Resolution 3.55 Å
|
