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8z4t

MERS-CoV S ectodomain trimer in complex with receptor DPP4-750E

Method: ELECTRON MICROSCOPY
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1. Protein Identity and Related Structures Protein Identity & Related Structures

Spike glycoprotein

Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012)

UniProt K9N5Q8

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein heterocomplex Heteromer Protein 5 Dipeptidyl peptidase 4 soluble form × 2 （P27487） Consistent with protein count

Other States of the Same Protein in the Database

Monomer
4zpw 4zpw

2 assemblies

Homodimer

None

Homotetramer

None

Other homooligomers
7x27 8z4o

2 assemblies

Heteromeric or nucleic-acid complex
4xak 4xak 4zpt 4zpt 4zpv 4zpv 6c6y 6c6y 7m55 8dgv 8dgx 8dgx

18 assemblies; showing the first 12

View Construct and Data Evidence
UniProt name SPIKE_MERS1
Isoform —
PDB entities 1
Chains and sequence ranges Author chain A； PDBConstruct 1–1206； UniProt 19–1224 Author chain B； PDBConstruct 1–1206； UniProt 19–1224 Author chain C； PDBConstruct 1–1206； UniProt 19–1224

Dipeptidyl peptidase 4 soluble form

Homo sapiens

UniProt P27487

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein heterocomplex Heteromer Protein 5 Spike glycoprotein × 3 （K9N5Q8） Consistent with protein count

Other States of the Same Protein in the Database

Monomer
2bub 2bub

2 assemblies

Homodimer
1j2e 1nu6 1pfq 1rwq 2ajl 2g5p 2g5t 2g63 2g63 2i03 2i03 2i78

44 assemblies; showing the first 12

Homotetramer

None

Other homooligomers

None

Heteromeric or nucleic-acid complex
1n1m 1nu8 1r9m 1r9m 1r9m 1r9m 1r9n 1r9n 1r9n 1tk3 1tkr 1u8e

124 assemblies; showing the first 12

View Construct and Data Evidence
UniProt name DPP4_HUMAN
Isoform —
PDB entities 2
Chains and sequence ranges Author chain D； PDBConstruct 1–728； UniProt 39–766 Author chain I； PDBConstruct 1–728； UniProt 39–766

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

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2. Structure Basics 2. Structure Basics

Entry ID entry_id8z4t
Deposition date deposition_date2024-04-17
Structure title titleMERS-CoV S ectodomain trimer in complex with receptor DPP4-750E
Keywords keywordsMERS-CoV, spike, DPP4, VIRAL PROTEIN; VIRAL PROTEIN
Experimental Method methodELECTRON MICROSCOPY
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3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

8z4t__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

8z4t__assembly_1__model_1 | I(q)

10-2 10-1 106 107 108 109 q (1/Angstrom) I(q)
100 plotted points; both axes use logarithmic scales.

8z4t__assembly_1__model_1 | P(r) · Pending

The new assembly/model P(r) has not been calculated yet This placeholder does not display legacy data r (Angstrom) P(r)
P(r) will be calculated and displayed separately for the same assembly/model.
Rg（Guinier）72.27 Å
Rg (electron density)72.48 Å
Total Rg72.28 Å
Atom count36433
Residues4687
Excluded volume643840 ų
Maximum q0.500 Å⁻¹
Assembly Model Structure unit Oligomeric description Status CRYSOL Actions
1 1 8z4t__assembly_1__model_1 pentameric （5） Success 4.1.3-1-20251215 (887e7ef) View Download
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4. Crystallography and Experiment 4. Crystallography & Experiment

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5. Entities and Polymers Entities & Polymers (2)

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7. Citations (1)