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9bw6

Human Vault Cage in complex with PARP4

Method: ELECTRON MICROSCOPY
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1. Protein Identity and Related Structures Protein Identity & Related Structures

Major vault protein

Homo sapiens

UniProt Q14764

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein heterocomplex Heteromer Protein 156 Protein mono-ADP-ribosyltransferase PARP4 × 78 （Q9UKK3） Consistent with protein count
2 Protein heterocomplex Heteromer Protein 4 Protein mono-ADP-ribosyltransferase PARP4 × 2 （Q9UKK3） Consistent with protein count

Other States of the Same Protein in the Database

Monomer
1y7x

1 assemblies

Homodimer
9mxj 9mxj 9mxv 9mxv

4 assemblies

Homotetramer

None

Other homooligomers
11dr 11dv 11ee 11eq 11fh 11jb 11jc 11jd 9bw5 9mxh 9mxj 9mxv

16 assemblies; showing the first 12

Heteromeric or nucleic-acid complex
11jf 9bw6 9bw6 9bw7 9bw7

5 assemblies

View Construct and Data Evidence
UniProt name MVP_HUMAN
Isoform —
PDB entities 1
Chains and sequence ranges Author chain A； PDBConstruct 1–893； UniProt 1–893 Author chain C； PDBConstruct 1–893； UniProt 1–893

Protein mono-ADP-ribosyltransferase PARP4

Homo sapiens

UniProt Q9UKK3

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein heterocomplex Heteromer Protein 156 Major vault protein × 78 （Q14764） Consistent with protein count
2 Protein heterocomplex Heteromer Protein 4 Major vault protein × 2 （Q14764） Consistent with protein count

Other States of the Same Protein in the Database

Monomer
8swy 8swy 8swy 8swz 8swz 8swz 8sx1 8sx1 8sx1 8sx1 8sx1 8sx1

21 assemblies; showing the first 12

Homodimer

None

Homotetramer

None

Other homooligomers

None

Heteromeric or nucleic-acid complex
11jf 9bw6 9bw6 9bw7 9bw7

5 assemblies

View Construct and Data Evidence
UniProt name PARP4_HUMAN
Isoform —
PDB entities 2
Chains and sequence ranges Author chain B； PDBConstruct 1–1724； UniProt 1–1724 Author chain D； PDBConstruct 1–1724； UniProt 1–1724

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

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2. Structure Basics 2. Structure Basics

Entry ID entry_id9bw6
Deposition date deposition_date2024-05-20
Structure title titleHuman Vault Cage in complex with PARP4
Keywords keywords;Vault, Vault Cage, MVP, Major Vault Protein, SPFH, PARP4, Poly(ADP-ribose)Polymerase 4, MINT, Poly(ADP-ribose)Polymerase, Ribonucleoprotein, Megadalton complex, TEP1, vault RNA, PROTEIN TRANSPORT ;; PROTEIN TRANSPORT
Experimental Method methodELECTRON MICROSCOPY
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3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

9bw6__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

9bw6__assembly_1__model_1 | I(q)

10-2 10-1 106 107 108 109 1010 1011 q (1/Angstrom) I(q)
100 plotted points; both axes use logarithmic scales.

9bw6__assembly_1__model_1 | P(r) · Pending

The new assembly/model P(r) has not been calculated yet This placeholder does not display legacy data r (Angstrom) P(r)
P(r) will be calculated and displayed separately for the same assembly/model.
Rg（Guinier）0.00 Å
Rg (electron density)221.50 Å
Total Rg221.80 Å
Atom count569556
Residues71682
Excluded volume10130000 ų
Maximum q0.500 Å⁻¹
Assembly Model Structure unit Oligomeric description Status CRYSOL Actions
1 1 9bw6__assembly_1__model_1 156-meric （156） Success 4.1.3-1-20251215 (887e7ef) View Download
2 1 9bw6__assembly_2__model_1 tetrameric （4） Excluded — —
Exclusion reason： Auxiliary symmetry representation; not a complete or representative biological assembly.
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4. Crystallography and Experiment 4. Crystallography & Experiment

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5. Entities and Polymers Entities & Polymers (2)

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7. Citations (4)