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9ck0

Cocrystal of PPARg LBD and NFKBIB / IKBB peptide with agonist GW1929

Method: X-RAY DIFFRACTION
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1. Protein Identity and Related Structures Protein Identity & Related Structures

Peroxisome proliferator-activated receptor gamma

Homo sapiens

UniProt P37231

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein heterocomplex Heteromer Protein 2 NF-kappa-B inhibitor beta × 1 （Q15653） (2~{S})-3-[4-[2-[methyl(pyridin-2-yl)amino]ethoxy]phenyl]-2-[[2-(phenylcarbonyl)phenyl]amino]propanoic acid × 1 Consistent with protein count

Other States of the Same Protein in the Database

Monomer
1i7i 1i7i 2f4b 2f4b 2om9 2om9 2om9 2om9 2prg 2qmv 2vsr 2vsr

158 assemblies; showing the first 12

Homodimer
1knu 1nyx 1prg 1zeo 2ath 2g0g 2i4j 2i4p 2i4z 2p4y 2pob 2q59

201 assemblies; showing the first 12

Homotetramer
2hwq 2hwr 4em9 4prg 9mah

5 assemblies

Other homooligomers

None

Heteromeric or nucleic-acid complex
1fm6 1fm6 1fm9 1k74 1rdt 1zgy 2fvj 2gtk 2prg 3b1m 3cs8 3cwd

137 assemblies; showing the first 12

View Construct and Data Evidence
UniProt name PPARG_HUMAN
Isoform —
PDB entities 1
Chains and sequence ranges Author chain A； PDBConstruct 2–276； UniProt 231–505

NF-kappa-B inhibitor beta

OrganismNot specified

UniProt Q15653

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein heterocomplex Heteromer Protein 2 Peroxisome proliferator-activated receptor gamma × 1 （P37231） (2~{S})-3-[4-[2-[methyl(pyridin-2-yl)amino]ethoxy]phenyl]-2-[[2-(phenylcarbonyl)phenyl]amino]propanoic acid × 1 Consistent with protein count

Other States of the Same Protein in the Database

Monomer

None

Homodimer

None

Homotetramer

None

Other homooligomers

None

Heteromeric or nucleic-acid complex
9ck0

1 assemblies

View Construct and Data Evidence
UniProt name IKBB_HUMAN
Isoform —
PDB entities 2
Chains and sequence ranges Author chain B； PDBConstruct 1–23； UniProt 277–299

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

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2. Structure Basics 2. Structure Basics

Entry ID entry_id9ck0
Deposition date deposition_date2024-07-08
Last revision last_revision2024-07-17
Structure title titleCocrystal of PPARg LBD and NFKBIB / IKBB peptide with agonist GW1929
Keywords keywordsNuclear Receptor, PPARg, PPAR gamma, Alpha Helix, NFKB, NFKB inhibitor, inflammation, type II diabetes, DNA BINDING PROTEIN; DNA BINDING PROTEIN
Experimental Method methodX-RAY DIFFRACTION
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3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

9ck0__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

9ck0__assembly_1__model_1 | I(q)

10-2 10-1 105 106 107 q (1/Angstrom) I(q)
100 plotted points; both axes use logarithmic scales.

9ck0__assembly_1__model_1 | P(r) · Pending

The new assembly/model P(r) has not been calculated yet This placeholder does not display legacy data r (Angstrom) P(r)
P(r) will be calculated and displayed separately for the same assembly/model.
Rg（Guinier）20.34 Å
Rg (electron density)19.00 Å
Total Rg20.08 Å
Atom count2265
Residues281
Excluded volume41070 ų
Maximum q0.500 Å⁻¹
Assembly Model Structure unit Oligomeric description Status CRYSOL Actions
1 1 9ck0__assembly_1__model_1 dimeric （2） Success 4.1.3-1-20251215 (887e7ef) View Download
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4. Crystallography and Experiment 4. Crystallography & Experiment

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5. Entities and Polymers Entities & Polymers (3)

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7. Citations (1)