9me1

hCXCR4-CXCL12 complex with 1:1 stoichiometry

Method: ELECTRON MICROSCOPY
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1. Protein Identity and Related Structures Protein Identity & Related Structures

C-X-C chemokine receptor type 4

Homo sapiens

UniProt P61073

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein heterocomplex Heteromer Protein 16 Stromal cell-derived factor 1 × 8 (P48061) Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name CXCR4_HUMAN
Isoform —
PDB entities 1
Chains and sequence ranges Author chain A; PDBConstruct 1–352; UniProt 1–352 Author chain B; PDBConstruct 1–352; UniProt 1–352 Author chain C; PDBConstruct 1–352; UniProt 1–352 Author chain D; PDBConstruct 1–352; UniProt 1–352 Author chain E; PDBConstruct 1–352; UniProt 1–352 Author chain I; PDBConstruct 1–352; UniProt 1–352 Author chain K; PDBConstruct 1–352; UniProt 1–352 Author chain L; PDBConstruct 1–352; UniProt 1–352

Stromal cell-derived factor 1

Homo sapiens

UniProt P48061

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein heterocomplex Heteromer Protein 16 C-X-C chemokine receptor type 4 × 8 (P61073) Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name SDF1_HUMAN
Isoform —
PDB entities 2
Chains and sequence ranges Author chain F; PDBConstruct 1–72; UniProt 22–93 Author chain G; PDBConstruct 1–72; UniProt 22–93 Author chain H; PDBConstruct 1–72; UniProt 22–93 Author chain J; PDBConstruct 1–72; UniProt 22–93 Author chain M; PDBConstruct 1–72; UniProt 22–93 Author chain N; PDBConstruct 1–72; UniProt 22–93 Author chain O; PDBConstruct 1–72; UniProt 22–93 Author chain P; PDBConstruct 1–72; UniProt 22–93

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

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2. Structure Basics 2. Structure Basics

Entry ID entry_id9me1
Deposition date deposition_date2024-12-05
Structure title titlehCXCR4-CXCL12 complex with 1:1 stoichiometry
Keywords keywordsHIV block, GPCR, SIGNALING PROTEIN; SIGNALING PROTEIN
Experimental Method methodELECTRON MICROSCOPY
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3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

9me1__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

9me1__assembly_1__model_1 | I(q)

10-2 10-1 106 107 108 109 q (1/Angstrom) I(q)
100 plotted points; both axes use logarithmic scales.

9me1__assembly_1__model_1 | P(r) · Pending

The new assembly/model P(r) has not been calculated yet This placeholder does not display legacy data r (Angstrom) P(r)
P(r) will be calculated and displayed separately for the same assembly/model.
Rg(Guinier)50.77 Å
Rg (electron density)51.74 Å
Total Rg52.21 Å
Atom count21155
Residues2768
Excluded volume383900 ų
Maximum q0.500 Å⁻¹
Assembly Model Structure unit Oligomeric description Status CRYSOL Actions
1 1 9me1__assembly_1__model_1 hexadecameric (16) Success 4.1.3-1-20251215 (887e7ef) View Download
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4. Crystallography and Experiment 4. Crystallography & Experiment

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5. Entities and Polymers Entities & Polymers (2)

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7. Citations (1)