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9o7f

CHIP E3 ligase dimer in Symmetric state bound to 2 Fab H1

Method: ELECTRON MICROSCOPY
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1. Protein Identity and Related Structures Protein Identity & Related Structures

E3 ubiquitin-protein ligase CHIP

Homo sapiens

UniProt Q9UNE7

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein heterocomplex Heteromer Protein 6 H1 Fab heavy chain × 2 H1 Fab light chain × 2 Consistent with protein count

Other States of the Same Protein in the Database

Monomer
9qeu 9qf1 9qfs 9qfy

4 assemblies

Homodimer
9r1p

1 assemblies

Homotetramer

None

Other homooligomers

None

Heteromeric or nucleic-acid complex
4kbq 4kbq 6efk 6efk 6nsv 6nsv 7tb1 7tb1 8ehz 8ehz 8ei0 8f14

36 assemblies; showing the first 12

View Construct and Data Evidence
UniProt name CHIP_HUMAN
Isoform —
PDB entities 1
Chains and sequence ranges Author chain A； PDBConstruct 1–277； UniProt 27–303 Author chain B； PDBConstruct 1–277； UniProt 27–303

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

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2. Structure Basics 2. Structure Basics

Entry ID entry_id9o7f
Deposition date deposition_date2025-04-15
Structure title titleCHIP E3 ligase dimer in Symmetric state bound to 2 Fab H1
Keywords keywordsU-box E3 ligase, Fab, Cryo-EM, Protein degradation, LIGASE-IMMUNE SYSTEM complex; LIGASE/IMMUNE SYSTEM
Experimental Method methodELECTRON MICROSCOPY
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3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

9o7f__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

9o7f__assembly_1__model_1 | I(q)

10-2 10-1 106 107 108 q (1/Angstrom) I(q)
100 plotted points; both axes use logarithmic scales.

9o7f__assembly_1__model_1 | P(r) · Pending

The new assembly/model P(r) has not been calculated yet This placeholder does not display legacy data r (Angstrom) P(r)
P(r) will be calculated and displayed separately for the same assembly/model.
Rg（Guinier）44.87 Å
Rg (electron density)44.89 Å
Total Rg44.92 Å
Atom count8648
Residues1434
Excluded volume79138 ų
Maximum q0.500 Å⁻¹
Assembly Model Structure unit Oligomeric description Status CRYSOL Actions
1 1 9o7f__assembly_1__model_1 hexameric （6） Success 4.1.3-1-20251215 (887e7ef) View Download
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4. Crystallography and Experiment 4. Crystallography & Experiment

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5. Entities and Polymers Entities & Polymers (3)

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7. Citations (1)