Neutralizing monoclonal antibody Fab fragment bound to leptin

entry_id	9puo
deposition_date	2025-07-31
last_revision	2025-11-05
title	Neutralizing monoclonal antibody Fab fragment bound to leptin
keywords	Antibody, FAB, leptin, IMMUNE SYSTEM; IMMUNE SYSTEM
method	X-RAY DIFFRACTION

rg_guinier	42.34 Å
rg_electron	43.19 Å
i0	208680000.00
molecular_weight	115950.0 kDa
excluded_volume	144640 ų
envelope_volume	202570 ų
shell_volume	43954 ų
envelope_diameter	160.0 Å
shell_rg	41.31 Å
envelope_rg	43.77 Å
shape_rg	43.17 Å
total_rg	43.15 Å
total_atoms	16168
n_residues	1084
n_harmonics	20
q_range	— – 0.5000 Å−1
n_points	101
shell_type	directional
solvent_density	0.3340 e/ų
contrast_shell	0.0300 e/ų
crysol_version	4.1.3

dmax	152.4 Å
rg_real	43.02 Å
rg_real_error	1.90 Å
i0_real	2.0870e+08
i0_real_error	4.0070e+06
rg_reciprocal	42.34 Å
i0_reciprocal	208500000.0000
total_estimate	0.7395
solution_quality	REASONABLE a REASONABLE solution
n_peaks	1
r_peak_primary	37.1 Å
skewness	0.746
kurtosis	0.116
angular_range	— – 0.1850 Å−1
current_alpha	0.0000
highest_alpha	23880000.0000
n_real_points	38
gnom_version	4.1.3
quality_criteria	AN1: 0.000; Oscil: 0.580; Stabil: 1.000; Sysdev: 1.000; Positv: 1.000; Valcen: 0.599; Smooth: 0.270

Unit Cell

length_a	51.927 Å
length_b	48.534 Å
length_c	124.963 Å
angle_alpha	90.34 °
angle_beta	85.21 °
angle_gamma	70.42 °
z_pdb	2

Symmetry

space_group	P 1
int_tables_number	1
crystal_system	triclinic

Refinement

resolution	3.100 Å
resolution_low	40.170 Å
r_factor	0.2403
r_work	0.2363
r_free	0.2772

Diffraction

temperature

100.0 K

Files (7)

• pr_distribution /app/data/pr_computation/pu/9puo/pr_distribution.json
• pr_output /app/data/pr_computation/pu/9puo/9puo.pr.out
• pr_plot /app/data/visualization/pr_computation/pu/9puo/9puo_pr_distribution.png
• saxs_curve_dat /app/data/saxs_computation/pu/9puo/9puo.dat
• saxs_fit /app/data/saxs_computation/pu/9puo/9puo.fit
• saxs_log /app/data/saxs_computation/pu/9puo/9puo.log
• saxs_plot /app/data/visualization/saxs_computation/pu/9puo/9puo_saxs_profile.png

Curves (3)

fit	/app/data/saxs_computation/pu/9puo/9puo.fit
pddf	/app/data/pr_computation/pu/9puo/9puo.pr.out
profile	/app/data/saxs_computation/pu/9puo/9puo.dat