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9q6n

Human Serum Albumin in complex with four nanobodies: nb118, nb68, N30 & N23

Method: ELECTRON MICROSCOPY D_max: 100.7 Å Quality: EXCELLENT

SAXS Profile

P(r) Distribution

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1. Structure Basics

entry_id	9q6n
deposition_date	2025-08-22
title	Human Serum Albumin in complex with four nanobodies: nb118, nb68, N30 & N23
keywords	Nanobody, VHH, IMMUNE SYSTEM; IMMUNE SYSTEM
method	ELECTRON MICROSCOPY

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Download Data

SAXS curve (.dat) P(r) distribution (.pr.out) Structure (CIF)

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2. SAXS Parameters (CRYSOL)

rg_guinier	33.29 Å
rg_electron	32.36 Å
i0	235394000.00
molecular_weight	119730.0 kDa
excluded_volume	148390 Å³
envelope_volume	185380 Å³
shell_volume	46970 Å³
envelope_diameter	107.5 Å
shell_rg	39.94 Å
envelope_rg	32.20 Å
shape_rg	32.34 Å
total_rg	32.98 Å
total_atoms	8399
n_residues	1077
n_harmonics	20
q_range	— – 0.5000 Å⁻¹
n_points	101
shell_type	directional
solvent_density	0.3340 e/Å³
contrast_shell	0.0300 e/Å³
crysol_version	4.1.3

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3. P(r) Analysis (GNOM)

dmax	100.7 Å
rg_real	33.11 Å
rg_real_error	0.59 Å
i0_real	2.3540e+08
i0_real_error	3.3570e+06
rg_reciprocal	33.22 Å
i0_reciprocal	235400000.0000
total_estimate	0.9067
solution_quality	EXCELLENT a EXCELLENT solution
n_peaks	2
r_peak_primary	44.0 Å
skewness	0.063
kurtosis	-0.566
angular_range	— – 0.2400 Å⁻¹
current_alpha	0.0000
highest_alpha	24910000.0000
n_real_points	49
gnom_version	4.1.3
quality_criteria	AN1: 0.000; Oscil: 0.957; Stabil: 1.000; Sysdev: 1.000; Positv: 1.000; Valcen: 0.987; Smooth: 0.926

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4. Crystallography & Experiment

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5. Entities & Polymer Info (5)

Entity 1 polymer

description	Albumin
formula_weight	66458.1 kDa
src_method	man
entity_count	1

Polymer

type	polypeptide(L)
strand_id	A
atom_count	8399

DAHKSEVAHRFKDLGEENFKALVLIAFAQYLQQCPFEDHVKLVNEVTEFAKTCVADESAENCDKSLHTLFGDKLCTVATLRETYGEMADCCAKQEPERNECFLQHKDDNPNLPRLVRPEVDVMCTAFHDNEETFLKKYLYEIARRHPYFYAPELLFFAKRYKAAFTECCQAADKAACLLPKLDELRDEGKASSAKQRLKCASLQKFGERAFKAWAVARLSQRFPKAEFAEVSKLVTDLTKVHTECCHGDLLECADDRADLAKYICENQDSISSKLKECCEKPLLEKSHCIAEVENDEMPADLPSLAADFVESKDVCKNYAEAKDVFLGMFLYEYARRHPDYSVVLLLRLAKTYETTLEKCCAAADPHECYAKVFDEFKPLVEEPQNLIKQNCELFEQLGEYKFQNALLVRYTKKVPQVSTPTLVEVSRNLGKVGSKCCKHPEAKRMPCAEDYLSVVLNQLCVLHEKTPVSDRVTKCCTESLVNRRPCFSALEVDETYVPKEFNAETFTFHADICTLSEKERQIKKQTALVELVKHKPKATKEQLKAVMDDFAAFVEKCCKADDKETCFAEEGKKLVAASQAALG

Source

organism	Homo sapiens
common_name	human
ncbi_taxonomy_id	9606
host_organism	Homo sapiens

Entity 2 polymer

description	nb118
formula_weight	13906.3 kDa
src_method	man
entity_count	1

Polymer

type	polypeptide(L)
strand_id	B

AQVQLVESGGGLVQAGGSLRLSCAASGFSFSSYGMGWFRQAPGKEREFVAAIGWIGSRTSYADSVKGRFTISKDNAKNTVYLQMDSLRPEDTAVYTCAATSYLNPDSDYARSDRSYGYRGQGTQVTVSE

Source

organism	Lama glama
ncbi_taxonomy_id	9844
host_organism	Escherichia coli

Entity 3 polymer

description	nb68
formula_weight	13447.8 kDa
src_method	man
entity_count	1

Polymer

type	polypeptide(L)
strand_id	C

VQLVESGGGLVQAGSSLRLSCAASGSTFSSHGMGWFRQAPGKEREFVATVSLSGRTTSYGDSVKDRFTISRDNAKNTVYLHMNSLKLEDTAVYYCAATSGGYYSRYAYDYYYWGQGTQVTVSE

Source

organism	Lama glama
ncbi_taxonomy_id	9844
host_organism	Escherichia coli

Entity 4 polymer

description	N30
formula_weight	12995.4 kDa
src_method	man
entity_count	1

Polymer

type	polypeptide(L)
strand_id	D

QLVESGGGLAQAGGSLRLSCAASGGTFSNSCMGWFRQAPGMEREFVAIIRSTGHTTYADSVEGRFTVSRDIAKNTVYLEMNSLKPEDTAVYSCVAGVSDYGCYRTSGIKYWGQGTQVTVSSE

Source

organism	Lama glama
ncbi_taxonomy_id	9844
host_organism	Escherichia coli

Entity 5 polymer

description	N23
formula_weight	13099.5 kDa
src_method	man
entity_count	1

Polymer

type	polypeptide(L)
strand_id	E

AQVQLVESGGGLVQAGGSLRLSCAASGRTPYVMGWFRQAPGNEREFVASISWTYGYTNYANSVKGRFRISKDNAKNTVLLQMNSLKPEDTAVYYCAARRGEDPEYDYWGQGTQVTVSSE

Source

organism	Lama glama
ncbi_taxonomy_id	9844
host_organism	Escherichia coli

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6. Citations (1)

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length_a	1.000 Å
length_b	1.000 Å
length_c	1.000 Å
angle_alpha	90.00 °
angle_beta	90.00 °
angle_gamma	90.00 °
z_pdb	—

space_group	P 1
int_tables_number	1
crystal_system	—

resolution	2.800 Å
resolution_low	— Å
r_factor	—
r_work	—
r_free	—

resolution	2.80 Å
resolution_method	—
num_particles	774416

fit	/app/data/saxs_computation/q6/9q6n/9q6n.fit
pddf	/app/data/pr_computation/q6/9q6n/9q6n.pr.out
profile	/app/data/saxs_computation/q6/9q6n/9q6n.dat

Human Serum Albumin in complex with four nanobodies: nb118, nb68, N30 & N23

SAXS Profile

P(r) Distribution

1. Structure Basics

Download Data

2. SAXS Parameters (CRYSOL)

3. P(r) Analysis (GNOM)

4. Crystallography & Experiment

Unit Cell

Symmetry

Refinement

EM 3D

5. Entities & Polymer Info (5)

Entity 1 polymer

Polymer

Source

Entity 2 polymer

Polymer

Source

Entity 3 polymer

Polymer

Source

Entity 4 polymer

Polymer

Source

Entity 5 polymer

Polymer

Source

6. Citations (1)

7. Files & Curves (10)

Files (7)

Curves (3)