BRCA1 BRCT tandem repeat with RNA polymerase II pSer5-CTD peptide

Method: X-RAY DIFFRACTION D_max: 132.6 Å Quality: GOOD

SAXS Profile

P(r) Distribution

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1. Structure Basics

entry_id	9qpx
deposition_date	2025-03-30
last_revision	2026-01-14
title	BRCA1 BRCT tandem repeat with RNA polymerase II pSer5-CTD peptide
keywords	BRCA BRCT repeat, RNA polymerase II, transcription regulation, DNA repair, PROTEIN BINDING; PROTEIN BINDING
method	X-RAY DIFFRACTION

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Download Data

SAXS curve (.dat) P(r) distribution (.pr.out) Structure (CIF)

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2. SAXS Parameters (CRYSOL)

rg_guinier	36.57 Å
rg_electron	36.17 Å
i0	144670000.00
molecular_weight	97122.0 kDa
excluded_volume	121480 Å³
envelope_volume	168310 Å³
shell_volume	39451 Å³
envelope_diameter	116.3 Å
shell_rg	42.13 Å
envelope_rg	35.24 Å
shape_rg	36.18 Å
total_rg	36.59 Å
total_atoms	6819
n_residues	868
n_harmonics	20
q_range	— – 0.5000 Å⁻¹
n_points	101
shell_type	directional
solvent_density	0.3340 e/Å³
contrast_shell	0.0300 e/Å³
crysol_version	4.1.3

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3. P(r) Analysis (GNOM)

dmax	132.6 Å
rg_real	36.50 Å
rg_real_error	1.47 Å
i0_real	1.4470e+08
i0_real_error	2.7530e+06
rg_reciprocal	36.55 Å
i0_reciprocal	144700000.0000
total_estimate	0.7748
solution_quality	GOOD a GOOD solution
n_peaks	2
r_peak_primary	46.2 Å
skewness	0.118
kurtosis	-0.814
angular_range	— – 0.2150 Å⁻¹
current_alpha	0.0000
highest_alpha	15450000.0000
n_real_points	44
gnom_version	4.1.3
quality_criteria	AN1: 0.000; Oscil: 0.755; Stabil: 1.000; Sysdev: 1.000; Positv: 1.000; Valcen: 0.803; Smooth: 0.000

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4. Crystallography & Experiment

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5. Entities & Polymer Info (2)

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6. Citations (1)

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length_a	112.827 Å
length_b	134.762 Å
length_c	180.381 Å
angle_alpha	90.00 °
angle_beta	90.00 °
angle_gamma	90.00 °
z_pdb	32

space_group	C 2 2 21
int_tables_number	20
crystal_system	—

resolution	3.000 Å
resolution_low	49.370 Å
r_factor	—
r_work	0.2551
r_free	0.3120

description	Breast cancer type 1 susceptibility protein
formula_weight	24602.3 kDa
ec_number	2.3.2.27
src_method	man
entity_count	4

type	polypeptide(L)
strand_id	A,D,B,C
atom_count	6819

BRCA1 BRCT tandem repeat with RNA polymerase II pSer5-CTD peptide

SAXS Profile

P(r) Distribution

1. Structure Basics

Download Data

2. SAXS Parameters (CRYSOL)

3. P(r) Analysis (GNOM)

4. Crystallography & Experiment

Unit Cell

Symmetry

Refinement

Diffraction

5. Entities & Polymer Info (2)

Entity 1 polymer

Polymer

Source

Entity 2 polymer

Polymer

6. Citations (1)

7. Files & Curves (10)

Files (7)

Curves (3)

organism	Homo sapiens
common_name	human
ncbi_taxonomy_id	9606
host_organism	Escherichia coli

description	DNA-directed RNA polymerase II subunit RPB1
formula_weight	1617.5 kDa
ec_number	2.7.7.6,3.1.13.-,2.7.7.48
src_method	syn
entity_count	3

fit	/app/data/saxs_computation/qp/9qpx/9qpx.fit
pddf	/app/data/pr_computation/qp/9qpx/9qpx.pr.out
profile	/app/data/saxs_computation/qp/9qpx/9qpx.dat