Cryo-EM structure of the inward-open choline-bound state of choline/ethanolamine transporter FLVCR2

Method: ELECTRON MICROSCOPY D_max: 75.3 Å Quality: GOOD

SAXS Profile

P(r) Distribution

▼

1. Structure Basics

entry_id	9qu4
deposition_date	2025-04-10
title	Cryo-EM structure of the inward-open choline-bound state of choline/ethanolamine transporter FLVCR2
keywords	Choline transporter, MEMBRANE PROTEIN; MEMBRANE PROTEIN
method	ELECTRON MICROSCOPY

▼

Download Data

SAXS curve (.dat) P(r) distribution (.pr.out) Structure (CIF)

▼

2. SAXS Parameters (CRYSOL)

rg_guinier	21.96 Å
rg_electron	21.08 Å
i0	26758100.00
molecular_weight	44440.0 kDa
excluded_volume	57628 Å³
envelope_volume	64441 Å³
shell_volume	24930 Å³
envelope_diameter	77.4 Å
shell_rg	28.43 Å
envelope_rg	21.52 Å
shape_rg	21.10 Å
total_rg	22.01 Å
total_atoms	6379
n_residues	402
n_harmonics	20
q_range	— – 0.5000 Å⁻¹
n_points	101
shell_type	directional
solvent_density	0.3340 e/Å³
contrast_shell	0.0300 e/Å³
crysol_version	4.1.3

▼

3. P(r) Analysis (GNOM)

dmax	75.3 Å
rg_real	21.89 Å
rg_real_error	0.52 Å
i0_real	2.6760e+07
i0_real_error	3.4250e+05
rg_reciprocal	21.90 Å
i0_reciprocal	26760000.0000
total_estimate	0.8697
solution_quality	GOOD a GOOD solution
n_peaks	2
r_peak_primary	25.9 Å
skewness	0.293
kurtosis	-0.295
angular_range	— – 0.3600 Å⁻¹
current_alpha	0.0000
highest_alpha	7023000.0000
n_real_points	68
gnom_version	4.1.3
quality_criteria	AN1: 0.000; Oscil: 0.783; Stabil: 1.000; Sysdev: 1.000; Positv: 1.000; Valcen: 0.978; Smooth: 0.975

▶

4. Crystallography & Experiment

▶

5. Entities & Polymer Info (2)

▶

6. Citations (1)

▶

length_a	1.000 Å
length_b	1.000 Å
length_c	1.000 Å
angle_alpha	90.00 °
angle_beta	90.00 °
angle_gamma	90.00 °
z_pdb	—

space_group	P 1
int_tables_number	1
crystal_system	triclinic

resolution	3.39 Å
resolution_method	—
num_particles	271101

description	Immunoglobulin G-binding protein A,Choline/ethanolamine transporter FLVCR2
formula_weight	66364.5 kDa
src_method	man
entity_count	1

type	polypeptide(L)
strand_id	A
atom_count	6379

Cryo-EM structure of the inward-open choline-bound state of choline/ethanolamine transporter FLVCR2

SAXS Profile

P(r) Distribution

1. Structure Basics

Download Data

2. SAXS Parameters (CRYSOL)

3. P(r) Analysis (GNOM)

4. Crystallography & Experiment

Unit Cell

Symmetry

EM 3D

5. Entities & Polymer Info (2)

Entity 1 polymer

Polymer

Source

Entity 2 non-polymer

6. Citations (1)

7. Files & Curves (10)

Files (7)

Curves (3)

organism	Homo sapiens
common_name	human
ncbi_taxonomy_id	9606
host_organism	Saccharomyces cerevisiae

description	CHOLINE ION
formula_weight	104.2 kDa
src_method	syn
entity_count	1

fit	/app/data/saxs_computation/qu/9qu4/9qu4.fit
pddf	/app/data/pr_computation/qu/9qu4/9qu4.pr.out
profile	/app/data/saxs_computation/qu/9qu4/9qu4.dat