CJM112 Fv in complex with human IL-17A

entry_id	9sg0
deposition_date	2025-08-21
last_revision	2025-10-29
title	CJM112 Fv in complex with human IL-17A
keywords	MONOCLONAL ANTIBODY, CYTOKINE, THERAPEUTIC ANTIBODY, FV FRAGMENT; CYTOKINE
method	X-RAY DIFFRACTION

rg_guinier	22.29 Å
rg_electron	21.30 Å
i0	23217500.00
molecular_weight	35813.0 kDa
excluded_volume	44418 ų
envelope_volume	54213 ų
shell_volume	21715 ų
envelope_diameter	78.0 Å
shell_rg	27.74 Å
envelope_rg	21.87 Å
shape_rg	21.23 Å
total_rg	22.33 Å
total_atoms	2520
n_residues	320
n_harmonics	20
q_range	— – 0.5000 Å−1
n_points	101
shell_type	directional
solvent_density	0.3340 e/ų
contrast_shell	0.0300 e/ų
crysol_version	4.1.3

dmax	74.9 Å
rg_real	22.25 Å
rg_real_error	0.40 Å
i0_real	2.3220e+07
i0_real_error	2.9710e+05
rg_reciprocal	22.26 Å
i0_reciprocal	23220000.0000
total_estimate	0.6251
solution_quality	REASONABLE a REASONABLE solution
n_peaks	2
r_peak_primary	27.2 Å
skewness	0.281
kurtosis	-0.343
angular_range	— – 0.3550 Å−1
current_alpha	0.0000
highest_alpha	4858000.0000
n_real_points	67
gnom_version	4.1.3
quality_criteria	AN1: 0.000; Oscil: 0.854; Stabil: 1.000; Sysdev: 0.189; Positv: 1.000; Valcen: 0.994; Smooth: 0.000

Unit Cell

length_a	55.720 Å
length_b	87.030 Å
length_c	156.260 Å
angle_alpha	90.00 °
angle_beta	90.00 °
angle_gamma	90.00 °
z_pdb	8

Symmetry

space_group	C 2 2 21
int_tables_number	20
crystal_system	—

Refinement

resolution	2.650 Å
resolution_low	78.130 Å
r_factor	0.1980
r_work	0.1950
r_free	0.2560

Diffraction

temperature

100.0 K

Files (7)

• pr_distribution /app/data/pr_computation/sg/9sg0/pr_distribution.json
• pr_output /app/data/pr_computation/sg/9sg0/9sg0.pr.out
• pr_plot /app/data/visualization/pr_computation/sg/9sg0/9sg0_pr_distribution.png
• saxs_curve_dat /app/data/saxs_computation/sg/9sg0/9sg0.dat
• saxs_fit /app/data/saxs_computation/sg/9sg0/9sg0.fit
• saxs_log /app/data/saxs_computation/sg/9sg0/9sg0.log
• saxs_plot /app/data/visualization/saxs_computation/sg/9sg0/9sg0_saxs_profile.png

Curves (3)

fit	/app/data/saxs_computation/sg/9sg0/9sg0.fit
pddf	/app/data/pr_computation/sg/9sg0/9sg0.pr.out
profile	/app/data/saxs_computation/sg/9sg0/9sg0.dat