Full-length Caspase-1-CARD filament

Method: ELECTRON MICROSCOPY D_max: 82.5 Å Quality: EXCELLENT

SAXS Profile

P(r) Distribution

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1. Structure Basics

entry_id	9wz6
deposition_date	2025-09-29
last_revision	2025-12-10
title	Full-length Caspase-1-CARD filament
keywords	filament, PYD, CARD, IMMUNE SYSTEM; IMMUNE SYSTEM
method	ELECTRON MICROSCOPY

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Download Data

SAXS curve (.dat) P(r) distribution (.pr.out) Structure (CIF)

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2. SAXS Parameters (CRYSOL)

rg_guinier	28.47 Å
rg_electron	27.54 Å
i0	103426000.00
molecular_weight	79790.0 kDa
excluded_volume	100420 Å³
envelope_volume	130020 Å³
shell_volume	38364 Å³
envelope_diameter	89.2 Å
shell_rg	35.74 Å
envelope_rg	27.06 Å
shape_rg	27.53 Å
total_rg	28.46 Å
total_atoms	5544
n_residues	712
n_harmonics	20
q_range	— – 0.5000 Å⁻¹
n_points	101
shell_type	directional
solvent_density	0.3340 e/Å³
contrast_shell	0.0300 e/Å³
crysol_version	4.1.3

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3. P(r) Analysis (GNOM)

dmax	82.5 Å
rg_real	28.23 Å
rg_real_error	0.35 Å
i0_real	1.0340e+08
i0_real_error	1.4160e+06
rg_reciprocal	28.31 Å
i0_reciprocal	103400000.0000
total_estimate	0.9112
solution_quality	EXCELLENT a EXCELLENT solution
n_peaks	2
r_peak_primary	38.3 Å
skewness	0.069
kurtosis	-0.561
angular_range	— – 0.2800 Å⁻¹
current_alpha	0.0000
highest_alpha	89120000.0000
n_real_points	57
gnom_version	4.1.3
quality_criteria	AN1: 0.000; Oscil: 0.971; Stabil: 1.000; Sysdev: 1.000; Positv: 1.000; Valcen: 0.982; Smooth: 0.946

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4. Crystallography & Experiment

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5. Entities & Polymer Info (1)

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6. Citations (1)

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length_a	1.000 Å
length_b	1.000 Å
length_c	1.000 Å
angle_alpha	90.00 °
angle_beta	90.00 °
angle_gamma	90.00 °
z_pdb	—

space_group	P 1
int_tables_number	1
crystal_system	—

resolution	2.660 Å
resolution_low	— Å
r_factor	—
r_work	—
r_free	—

resolution	2.66 Å
resolution_method	—
num_particles	1565512

description	Caspase-1
formula_weight	45213.6 kDa
ec_number	3.4.22.36
src_method	man
entity_count	8

Full-length Caspase-1-CARD filament

SAXS Profile

P(r) Distribution

1. Structure Basics

Download Data

2. SAXS Parameters (CRYSOL)

3. P(r) Analysis (GNOM)

4. Crystallography & Experiment

Unit Cell

Symmetry

Refinement

EM 3D

5. Entities & Polymer Info (1)

Entity 1 polymer

Polymer

Source

6. Citations (1)

7. Files & Curves (10)

Files (7)

Curves (3)

organism	Homo sapiens
common_name	human
ncbi_taxonomy_id	9606
host_organism	Homo sapiens

fit	/app/data/saxs_computation/wz/9wz6/9wz6.fit
pddf	/app/data/pr_computation/wz/9wz6/9wz6.pr.out
profile	/app/data/saxs_computation/wz/9wz6/9wz6.dat

type	polypeptide(L)
strand_id	A,B,C,D,E,F,G,H
atom_count	5544