Crystal structure of FOXM1 DNA binding domain to specific dsDNA substrate

entry_id	9xs1
deposition_date	2025-11-20
last_revision	2026-04-15
title	Crystal structure of FOXM1 DNA binding domain to specific dsDNA substrate
keywords	transcription factor, DNA-binding domain, DNA BINDING PROTEIN/DNA, DNA BINDING PROTEIN-DNA complex; DNA BINDING PROTEIN/DNA
method	X-RAY DIFFRACTION

rg_guinier	30.10 Å
rg_electron	28.77 Å
i0	84554400.00
molecular_weight	54382.0 kDa
excluded_volume	60099 ų
envelope_volume	89721 ų
shell_volume	27234 ų
envelope_diameter	97.2 Å
shell_rg	34.39 Å
envelope_rg	28.13 Å
shape_rg	28.66 Å
total_rg	29.44 Å
total_atoms	3717
n_residues	310
n_harmonics	20
q_range	— – 0.5000 Å−1
n_points	101
shell_type	directional
solvent_density	0.3340 e/ų
contrast_shell	0.0300 e/ų
crysol_version	4.1.3

dmax	92.5 Å
rg_real	30.01 Å
rg_real_error	0.75 Å
i0_real	8.4550e+07
i0_real_error	1.2580e+06
rg_reciprocal	30.05 Å
i0_reciprocal	84560000.0000
total_estimate	0.8954
solution_quality	GOOD a GOOD solution
n_peaks	2
r_peak_primary	45.4 Å
skewness	0.080
kurtosis	-0.636
angular_range	— – 0.2650 Å−1
current_alpha	0.0000
highest_alpha	3917000.0000
n_real_points	54
gnom_version	4.1.3
quality_criteria	AN1: 0.000; Oscil: 0.936; Stabil: 1.000; Sysdev: 1.000; Positv: 1.000; Valcen: 0.991; Smooth: 0.836

Unit Cell

length_a	72.210 Å
length_b	45.610 Å
length_c	213.494 Å
angle_alpha	90.00 °
angle_beta	95.82 °
angle_gamma	90.00 °
z_pdb	12

Symmetry

space_group	I 1 2 1
int_tables_number	5
crystal_system	—

Refinement

resolution	2.500 Å
resolution_low	30.400 Å
r_factor	0.2144
r_work	0.2126
r_free	0.2486

Diffraction

temperature

100.0 K

Files (7)

• pr_distribution /app/data/pr_computation/xs/9xs1/pr_distribution.json
• pr_output /app/data/pr_computation/xs/9xs1/9xs1.pr.out
• pr_plot /app/data/visualization/pr_computation/xs/9xs1/9xs1_pr_distribution.png
• saxs_curve_dat /app/data/saxs_computation/xs/9xs1/9xs1.dat
• saxs_fit /app/data/saxs_computation/xs/9xs1/9xs1.fit
• saxs_log /app/data/saxs_computation/xs/9xs1/9xs1.log
• saxs_plot /app/data/visualization/saxs_computation/xs/9xs1/9xs1_saxs_profile.png

Curves (3)

fit	/app/data/saxs_computation/xs/9xs1/9xs1.fit
pddf	/app/data/pr_computation/xs/9xs1/9xs1.pr.out
profile	/app/data/saxs_computation/xs/9xs1/9xs1.dat