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Protein Structures and Oligomeric States

Enter a protein name, UniProt accession or PDB ID. Name searches ask you to confirm the protein identity before related structures are queried.

Current Protein Identity：A8MT69 New Search
17PDB entries
28Biological assembly
63chain/assembly records
Main Difference Dimensions in This Set
Different construct Different mutation/modification Different assembly state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics

Difference tags compare only the current result set; every original PDB and assembly record remains separate.

Related-Structure Differences

Each row represents one biological assembly in one PDB entry; multiple monomers of the same protein are listed separately.

PDB Entry Assembly / Oligomeric State Construct Mutations and Modifications Ligands, Ions and Non-polymers Experimental Method Experimental Conditions Structure Quality
28OP Structure of the human inner kinetochore CCAN and CENP-C bound to DNA Deposited 2026-02-11 Assembly 1 Insufficient information Heteromer；Protein × 16 PDB declaration: 18-meric（18） Consistent with all polymers
Chain X 1–81（81 aa）
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 7.4
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 2.70 Å
4DRA Crystal structure of MHF complex Deposited 2012-02-17 Assembly 1 Protein heterocomplex Heteromer；Protein × 4 PDB declaration: tetrameric（4） Consistent with protein count
Chain E 1–81（81 aa）
Chain H 1–81（81 aa）
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 6.8；285 K；0.1M HEPES-NaOH, pH 6.8, VAPOR DIFFUSION, HANGING DROP, temperature 285K
Resolution 2.41 Å R-free 0.242
4DRA Crystal structure of MHF complex Deposited 2012-02-17 Assembly 2 Protein heterocomplex Heteromer；Protein × 4 PDB declaration: tetrameric（4） Consistent with protein count
Chain F 1–81（81 aa）
Chain G 1–81（81 aa）
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 6.8；285 K；0.1M HEPES-NaOH, pH 6.8, VAPOR DIFFUSION, HANGING DROP, temperature 285K
Resolution 2.41 Å R-free 0.242
4DRB The crystal structure of FANCM bound MHF complex Deposited 2012-02-17 Assembly 1 Protein heterocomplex Heteromer；Protein × 5 PDB declaration: pentameric（5） Consistent with protein count
Chain J 1–81（81 aa）
Chain K 1–81（81 aa）
Non-standard monomer：Yes (specific site not provided by mmCIF) Non-standard monomer：Yes (specific site not provided by mmCIF) No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 8.5；285 K；0.1M Tris-HCl, pH 8.5, 0.2 M (NH4)2SO4, 25% PEG 3350 , VAPOR DIFFUSION, HANGING DROP, temperature 285K
Resolution 2.63 Å R-free 0.256
4DRB The crystal structure of FANCM bound MHF complex Deposited 2012-02-17 Assembly 2 Protein heterocomplex Heteromer；Protein × 5 PDB declaration: pentameric（5） Consistent with protein count
Chain L 1–81（81 aa）
Chain M 1–81（81 aa）
Non-standard monomer：Yes (specific site not provided by mmCIF) Non-standard monomer：Yes (specific site not provided by mmCIF) No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 8.5；285 K；0.1M Tris-HCl, pH 8.5, 0.2 M (NH4)2SO4, 25% PEG 3350 , VAPOR DIFFUSION, HANGING DROP, temperature 285K
Resolution 2.63 Å R-free 0.256
4DRB The crystal structure of FANCM bound MHF complex Deposited 2012-02-17 Assembly 3 Protein heterocomplex Heteromer；Protein × 5 PDB declaration: pentameric（5） Consistent with protein count
Chain N 1–81（81 aa）
Chain O 1–81（81 aa）
Non-standard monomer：Yes (specific site not provided by mmCIF) Non-standard monomer：Yes (specific site not provided by mmCIF) No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 8.5；285 K；0.1M Tris-HCl, pH 8.5, 0.2 M (NH4)2SO4, 25% PEG 3350 , VAPOR DIFFUSION, HANGING DROP, temperature 285K
Resolution 2.63 Å R-free 0.256
4E44 Crystal structure of the hMHF1/hMHF2 Histone-Fold Tetramer Deposited 2012-03-12 Assembly 1 Protein heterocomplex Heteromer；Protein × 4 PDB declaration: tetrameric（4） Consistent with protein count
Chain B 1–81（81 aa）
Chain D 1–81（81 aa）
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 7.8；298 K；Tracking Code C4, 0.1M Tris pH 7.8, 0.2M LiCl, 0.1M Na2SO4, 17.5% w/v PEG3350, 10% glycerol cryo., vapor diffusion, sitting drop, temperature 298K
Resolution 2.10 Å R-free 0.231
4E45 Crystal structure of the hMHF1/hMHF2 Histone-Fold Tetramer in Complex with Fanconi Anemia Associated Helicase hFANCM Deposited 2012-03-12 Assembly 1 Protein heterocomplex Heteromer；Protein × 5 PDB declaration: pentameric（5） Consistent with protein count
Chain B 1–81（81 aa）
Chain D 1–81（81 aa）
Not recorded GOL GLYCEROL × 1 ZN ZINC ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 7.8；298 K；Tracking Code C4, 0.1M Tris pH 7.8, 0.2M LiCl, 0.1M Na2SO4, 17.5% w/v PEG3350, 10% glycerol cryo., vapor diffusion, sitting drop, temperature 298K
Resolution 2.00 Å R-free 0.245
4E45 Crystal structure of the hMHF1/hMHF2 Histone-Fold Tetramer in Complex with Fanconi Anemia Associated Helicase hFANCM Deposited 2012-03-12 Assembly 2 Protein heterocomplex Heteromer；Protein × 5 PDB declaration: pentameric（5） Consistent with protein count
Chain G 1–81（81 aa）
Chain I 1–81（81 aa）
Not recorded GOL GLYCEROL × 1 ZN ZINC ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 7.8；298 K；Tracking Code C4, 0.1M Tris pH 7.8, 0.2M LiCl, 0.1M Na2SO4, 17.5% w/v PEG3350, 10% glycerol cryo., vapor diffusion, sitting drop, temperature 298K
Resolution 2.00 Å R-free 0.245
4E45 Crystal structure of the hMHF1/hMHF2 Histone-Fold Tetramer in Complex with Fanconi Anemia Associated Helicase hFANCM Deposited 2012-03-12 Assembly 3 Protein heterocomplex Heteromer；Protein × 5 PDB declaration: pentameric（5） Consistent with protein count
Chain L 1–81（81 aa）
Chain N 1–81（81 aa）
Not recorded ZN ZINC ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 7.8；298 K；Tracking Code C4, 0.1M Tris pH 7.8, 0.2M LiCl, 0.1M Na2SO4, 17.5% w/v PEG3350, 10% glycerol cryo., vapor diffusion, sitting drop, temperature 298K
Resolution 2.00 Å R-free 0.245
4NDY Human MHF1-MHF2 DNA complex Deposited 2013-10-28 Assembly 1 Protein–DNA Heteromer；Protein × 4 PDB declaration: hexameric（6） Consistent with all polymers
Chain M 8–81（74 aa）
Chain N 8–81（74 aa）
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions Micro-batch under oil；300 K；0.1-0.3M Ammonium Phosphate, Micro-batch under oil, temperature 300K
Resolution 7.00 Å R-free 0.279
4NDY Human MHF1-MHF2 DNA complex Deposited 2013-10-28 Assembly 2 Protein–DNA Heteromer；Protein × 4 PDB declaration: octameric（8） Consistent with all polymers
Chain L 8–81（74 aa）
Chain U 8–81（74 aa）
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions Micro-batch under oil；300 K；0.1-0.3M Ammonium Phosphate, Micro-batch under oil, temperature 300K
Resolution 7.00 Å R-free 0.279
4NDY Human MHF1-MHF2 DNA complex Deposited 2013-10-28 Assembly 3 Protein–DNA Heteromer；Protein × 4 PDB declaration: hexameric（6） Consistent with all polymers
Chain V 8–81（74 aa）
Chain W 8–81（74 aa）
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions Micro-batch under oil；300 K；0.1-0.3M Ammonium Phosphate, Micro-batch under oil, temperature 300K
Resolution 7.00 Å R-free 0.279
4NDY Human MHF1-MHF2 DNA complex Deposited 2013-10-28 Assembly 4 Protein heterocomplex Heteromer；Protein × 4 PDB declaration: tetrameric（4） Consistent with protein count
Chain B 8–81（74 aa）
Chain X 8–81（74 aa）
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions Micro-batch under oil；300 K；0.1-0.3M Ammonium Phosphate, Micro-batch under oil, temperature 300K
Resolution 7.00 Å R-free 0.279
4NDY Human MHF1-MHF2 DNA complex Deposited 2013-10-28 Assembly 5 Protein heterocomplex Heteromer；Protein × 4 PDB declaration: tetrameric（4） Consistent with protein count
Chain D 8–81（74 aa）
Chain H 8–81（74 aa）
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions Micro-batch under oil；300 K；0.1-0.3M Ammonium Phosphate, Micro-batch under oil, temperature 300K
Resolution 7.00 Å R-free 0.279
4NE1 Human MHF1 MHF2 DNA complexes Deposited 2013-10-28 Assembly 1 Protein–DNA Heteromer；Protein × 20 PDB declaration: 24-meric（24） Consistent with all polymers
Chain B 8–81（74 aa）
Chain D 8–81（74 aa）
Chain H 8–81（74 aa）
Chain L 8–81（74 aa）
Chain M 8–81（74 aa）
Chain N 8–81（74 aa）
Chain U 8–81（74 aa）
Chain V 8–81（74 aa）
Chain W 8–81（74 aa）
Chain X 8–81（74 aa）
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions Micro-batch under oil；300 K；0.1-0.3M ammonium phosphate, Micro-batch under oil, temperature 300K
Resolution 6.50 Å R-free 0.295
4NE1 Human MHF1 MHF2 DNA complexes Deposited 2013-10-28 Assembly 2 Protein–DNA Heteromer；Protein × 20 PDB declaration: 24-meric（24） Consistent with all polymers
Chain Z 8–81（74 aa）
Chain b 8–81（74 aa）
Chain d 8–81（74 aa）
Chain h 8–81（74 aa）
Chain i 8–81（74 aa）
Chain j 8–81（74 aa）
Chain o 8–81（74 aa）
Chain p 8–81（74 aa）
Chain q 8–81（74 aa）
Chain r 8–81（74 aa）
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions Micro-batch under oil；300 K；0.1-0.3M ammonium phosphate, Micro-batch under oil, temperature 300K
Resolution 6.50 Å R-free 0.295
4NE3 Human MHF1-MHF2 complex Deposited 2013-10-28 Assembly 1 Protein heterocomplex Heteromer；Protein × 4 PDB declaration: tetrameric（4） Consistent with protein count
Chain B 8–81（74 aa）
Non-standard monomer：Yes (specific site not provided by mmCIF) No recorded non-water small molecule X-RAY DIFFRACTION mmCIF provides none of the parsed conditions Resolution 1.80 Å R-free 0.252
4NE5 Human MHF1-MHF2 complex Deposited 2013-10-28 Assembly 1 Protein heterocomplex Heteromer；Protein × 4 PDB declaration: tetrameric（4） Consistent with protein count
Chain B 8–81（74 aa）
Chain F 8–81（74 aa）
Non-standard monomer：Yes (specific site not provided by mmCIF) Non-standard monomer：Yes (specific site not provided by mmCIF) No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions Micro-batch under oil；300 K；Micro-batch under oil, temperature 300K
Resolution 2.50 Å R-free 0.264
4NE5 Human MHF1-MHF2 complex Deposited 2013-10-28 Assembly 2 Protein heterocomplex Heteromer；Protein × 4 PDB declaration: tetrameric（4） Consistent with protein count
Chain D 8–81（74 aa）
Chain H 8–81（74 aa）
Non-standard monomer：Yes (specific site not provided by mmCIF) Non-standard monomer：Yes (specific site not provided by mmCIF) No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions Micro-batch under oil；300 K；Micro-batch under oil, temperature 300K
Resolution 2.50 Å R-free 0.264
4NE6 Human MHF1-MHF2 complex Deposited 2013-10-28 Assembly 1 Protein heterocomplex Heteromer；Protein × 4 PDB declaration: tetrameric（4） Consistent with protein count
Chain B 8–81（74 aa）
Chain D 8–81（74 aa）
Non-standard monomer：Yes (specific site not provided by mmCIF) Non-standard monomer：Yes (specific site not provided by mmCIF) No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions Micro-batch under oil；300 K；Micro-batch under oil, temperature 300K
Resolution 2.10 Å R-free 0.262
7R5S Structure of the human CCAN bound to alpha satellite DNA Deposited 2022-02-11 Assembly 1 Protein–DNA Heteromer；Protein × 15 PDB declaration: heptadecameric（17） Consistent with all polymers
Chain X 1–81（81 aa）
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 7.8
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 2.83 Å
7XHN Structure of human inner kinetochore CCAN-DNA complex Deposited 2022-04-09 Assembly 1 Protein–DNA Heteromer；Protein × 18 PDB declaration: eicosameric（20） Consistent with all polymers
Chain X 1–81（81 aa）
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 7.5
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 3.71 Å
7XHO Structure of human inner kinetochore CCAN complex Deposited 2022-04-09 Assembly 1 Protein heterocomplex Heteromer；Protein × 17 PDB declaration: heptadecameric（17） Consistent with protein count
Chain X 1–81（81 aa）
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 7.5
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 3.29 Å
7YWX Structure of the human CCAN CENP-A alpha-satellite complex Deposited 2022-02-14 Assembly 1 Protein–DNA Heteromer；Protein × 25 PDB declaration: 27-meric（27） Consistent with all polymers
Chain X 1–81（81 aa）
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 7.8
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 12.00 Å
9TAW Structure of the human inner kinetochore CCAN bound to DNA Deposited 2025-11-18 Assembly 1 Protein–DNA Heteromer；Protein × 16 PDB declaration: 18-meric（18） Consistent with all polymers
Chain X 1–81（81 aa）
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 7.8
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 3.54 Å
9TAX Structure of the human inner kinetochore CCAN bound to a mono-CENP-A nucleosome Deposited 2025-11-18 Assembly 1 Protein–DNA Heteromer；Protein × 25 PDB declaration: 27-meric（27） Consistent with all polymers
Chain X 1–81（81 aa）
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 7.4
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 4.50 Å
9TAY Structure of the human inner kinetochore CCAN bound to a di-CENP-A nucleosome Deposited 2025-11-18 Assembly 1 Insufficient information Heteromer；Protein × 35 PDB declaration: 37-meric（37） Consistent with all polymers
Chain X 1–81（81 aa）
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 7.4
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 15.50 Å

This page presents structural evidence recorded in PDB/mmCIF.“No recorded non-water small molecule” does not prove that the experimental sample was ligand-free; experimental conditions belong to the PDB experiment, while ligands and copy counts are shown for each biological assembly.